Development and Application of the DORIAN (Dose-Response Information Analysis) System
EPA Grant Number: R832721C001Subproject: this is subproject number 001 , established and managed by the Center Director under grant R832721
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
Center: New Jersey Research Center for Environmental Bioinformatics and Computational Toxicology
Center Director: Welsh, William J.
Title: Development and Application of the DORIAN (Dose-Response Information Analysis) System
Investigators: Georgopoulos, Panos G. , Tong, Weida
Current Investigators: Georgopoulos, Panos G. , Androulakis, Ioannis , Floudas, Christodoulos , Ierapetritou, Marianthi , Rabitz, Herschel , Tong, Weida , Welsh, William J.
Institution: Rutgers University , U.S. Food and Drug Administration
Current Institution: Princeton University , Rutgers University , U.S. Food and Drug Administration , University of Medicine and Dentistry of New Jersey
EPA Project Officer: Mustra, David
Project Period: October 1, 2005 through September 30, 2010
RFA: Computational Toxicology: Environmental Bioinformatics Research Center (2004)
Research Category: Computational Toxicology
Description:
Objective:The aims of this project have not changed from the original application; original objectives for the report period have been met. However, specific collaborative case studies have been defined during the report period to facilitate testing and evaluating of the accomplishment of these aims.
Publications and Presentations:Publications have been submitted on this subproject: View all 7 publications for this subproject | View all 103 publications for this center
Supplemental Keywords:computational toxicology, toxicogenomics, bioinformatics, toxicoinformatics, proteomics, metabonomics, physiomics, cytomics, genomics, transcriptomics, enviroinformatics, cheminformatics, biologically based dose-response modeling, cross-species extrapolation, risk assessment,
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ENVIRONMENTAL MANAGEMENT, Geographic Area, Scientific Discipline, Health, Risk Assessment, Biology, Risk Assessments, Biochemistry, Environmental Monitoring, State, exposure assessment, biochemical research, chemical composition, ecological risk assessment, toxicologic assessment, bioinformatics, human health risk, biopollution, toxicology, environmental risks, risk, outreach and training, computational toxicology, New Jersey (NJ)
Progress and Final Reports:
2006 Progress Report
2007 Progress Report
Main Center Abstract and Reports:
R832721 New Jersey Research Center for Environmental Bioinformatics and Computational Toxicology
Subprojects under this Center:
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R832721C001 Development and Application of the DORIAN (Dose-Response Information Analysis) System
R832721C002 Hepatocyte Metabolism Model for Xenobiotics
R832721C003 Development of Computational Tools for Optimal Identification of Biological Networks
R832721C004 Cheminformatics Tools for Toxicant Characterization
R832721C005 Optimization Tools for In Silico Structural Proteomics