Carbon disulfide Quickview (CASRN 75-15-0)

Status of Data for Carbon disulfide

File First On-Line: 09/30/1987; Last Significant Revision: 08/01/1995

Category (section)	Status	Last Revised
Oral RfD Assessment	On-line	09/01/1990
Inhalation RfC Assessment	On-line	08/01/1995
Carcinogenicity Assessment	No data

Synonyms

75-15-0 Carbon bisulfide Carbon bisulphide Carbon disulfide Carbon disulphide

Carbone (sufure de) Carbonio (solfuro di) Carbon sulfide Carbon sulphide more...

Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect	Point of Departure*	UF	MF	RfD
Fetal toxicity/ malformations	NOEL : 11 mg/kg-day	100	1	1 x10-1 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

• Principal and Supporting Studies (Oral RfD)
  • Rabbit inhalation teratogenic study, Hardin et al., 1981
• Confidence in the Oral RfD
  • Study -- Medium
  • Database -- Medium
  • RfD -- Medium

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Critical Effect	Point of Departure*	UF	MF	RfC
Peripheral nervous system dysfunction	BMC10 (HEC): 19.7 mg/m3	30	1	7x10-1 mg/m3

* The Point of Departure listed serves as a basis from which the Inhalation RfC was derived. See Discussion of Conversion Factors and Assumptions for more details.

• Principal and Supporting Studies (Inhalation RfC)
  • Occupational study, Johnson et al., 1983
• Confidence in the Inhalation RfC
  • Study -- Medium
  • Database -- Medium
  • RfC -- Medium

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Carcinogenicity Assessment for Lifetime Exposure

• Weight-of-Evidence Characterization
  • Not Assessed under the IRIS Program.

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Quantitative Estimate of Carcinogenic Risk from Oral Exposure

• Not Assessed under the IRIS Program.

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Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

• Not Assessed under the IRIS Program.