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Agricultural Research Service United States Department of Agriculture
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Allen D Smith
Diet, Genomics and Immunology Lab
Research Virologist

Phone: (301) 504-8577 ext. 280
Fax: (301) 504-9062
Room 228
10300 BALTIMORE AVENUE
BLDG 307-C BARC-EAST
307 BARC-EAST
BELTSVILLE, MD, 20705-2350

Projects
IMPACT OF NUTRITIONAL STATUS ON IMMUNE-INDUCED CHANGES IN GUT FUNCTION
Appropriated (D)
  Accession Number: 408279
EFFECT OF DIETARY INDUCED OXIDATIVE STRESS ON INTESTINAL PHYSIOLOGY AND THE DEVELOPMENT OF MUCOSAL IMMUNITY TO ENTERIC PATHOGENS
Appropriated (D)
  Accession Number: 408041

Publications
Copper deficiency increases the virulence of amyocarditic and myocarditic strains of cocksackievirus B3 in Mice - (Peer Reviewed Journal)
Smith, A.D., Botero, S., Levander, O. 2008. Copper deficiency increases the virulence of amyocarditic and myocarditic strains of cocksackievirus B3 in mice. Journal of Nutrition. 138(5):849-55.
Intestinal inflammation caused by magnesium deficiency alters basal and oxidative stress-induced intestinal function - (Peer Reviewed Journal)
Scanlan, B.J., Tuft, B., Elfrey, J.E., Smith, A., Zhao, A., Morimoto, M., Chmielinska, J.J., Tejero-Taldo, M.I., Mak, I.T., Weglicki, W.B., and Shea-Donohue, T. 2007. Intestinal inflammation caused by magnesium deficiency alters basal and oxidative stress-induced intestinal function. Molecular and Cellular Biochemistry. Jul27;[Epub ahead of print].
Selenium (Se) deficiency alters intestinal diaphorase activity in mice infected with the intestinal parasitic worm Heligmosomoides polygyrus - (Abstract)
Urban Jr, J.F., Smith, A.D., Botero, S., Dawson, H.D., Anthony, R., Gause, W., Shea-Donohue, T. 2007. Selenium (Se) deficiency alters intestinal diaphorase activity in mice infected with the intestinal parasitic worm Heligmosomoides polygyrus. Experimental Biology.
COPPER DEFICIENCY INCREASES THE VIRULENCE OF COXSACKIEVIRUS B3 INFECTIONS IN MICE. - (Abstract)
Smith, A.D., Botero, S., Levander, O.A. 2006. Copper deficiency increases the virulence of coxsackievirus B3 infections in mice [abstract]. Federation of American Societies for Experimental Biology Conference. 20(4):A554.
GLUTATHIONE IS REQUIRED FOR EFFICIENT PRODUCTION OF INFECTIOUS PICORNAVIRUSES VIRIONS - (Peer Reviewed Journal)
Smith, A.D., Dawson, H.D. 2006. Glutathione is required for efficient production of infectious picornavirus virions. Electronic Virology. Available: http://www.sciencedirect.com/
EFFECT OF PHYSICAL RESTRAINT ON OXIDATIVE STRESS IN MICE FED A SELENIUM AND VITAMIN E DEFICIENT DIET - (Abstract)
South, P., Smith, A.D., Guidry, C.A., Levander, O.A. 2006. Effect of physical restraint on oxidative stress in mice fed a selenium and vitamin e deficient diet[abstract]. Biological Trace Element Research. 109(3):293-300.
EFFECT OF PHYSICAL RESTRAINT ON OXIDATIVE STRESS IN MICE FED A SELENIUM AND VITAMIN E DEFICIENT DIET - (Peer Reviewed Journal)
South, P.K., Smith, A.D., Guidry, C.A., Levander, O.A. 2006. Effect of physical restraint on oxidative stress in mice fed a selenium and vitamin E deficient diet. Biological Trace Element Research. 109(3):293-300.
PRETREATMENT OF HELA CELLS WITH THE GLUTATHIONE SYNTHESIS INHIBITOR, L-BUTHIONINE-SULFOXIMINE (BSO), INHIBITS REPLICATION OF PICORNAVIRUSES - (Abstract)
Smith, A.D. 2005. Pretreatment of hela cells with the glutathione synthesis inhibitor, l-buthionine-sulfoximine (bso), inhibits replication of picornaviruses. Federation of American Societies for Experimental Biology Conference.
EFFECT OF SELENIUM AND/OR VITAMIN E DEFICIENCIES ON HELIGMOSOMOIDES POLYGYRUS INFECTIONS IN MICE - (Peer Reviewed Journal)
Smith, A.D., Madden, K. B., Au Yeung, K., Zhao, A., Elfrey, J., Finkelman, F., Levander, O.A., Shea Donohue, P.T., and Urban Jr, J.F. 2005. Effect of selenium and/or vitamin E deficiencies on Heligmosomoides polygyrus infections in mice. Journal of Nutrition. 135:830-836.
IMPACT OF VITAMIN E OR SELENIUM DEFICIENCY ON NEMATODE-INDUCED ALERATIONS IN MURINE INTESTINAL FUNCTION - (Peer Reviewed Journal)
Auyeung, K., Smith, A.D., Zhao, A., Madden, K., Elfrey, J., Sullivan, C., Levander, O.A., Urban Jr, J.F., Shea Donohue, P.T. 2005. Impact of vitamin E or selenium deficiency on nematode-induced alerations in murine intestinal function. Experimental Parasitology. 109:201-208.
MEMBRANE-DERIVED OLIGOSACCHARIDES OF SALMONELLA ENTERICA SEROVAR TYPHIMURIUM - (Abstract)
Jun, W., Bhagwat, A.A., Gross, K.C., Smith, A.D., Angle, S.J. 2004. Membrane-derived oligosaccharides of Salmonella enterica serovar Typhimurium. American Society for Microbiology Annual Meeting. p. 107.
SELENIUM (SE) AND VITAMIN E (VE) DEFICIENCIES IMPAIR INTESTINAL FUNCTION AND RESULT IN PERSISTENT INFECTION WITH HELIGMOSOMOIDES POLYGYRUS - (Abstract)
Smith, A.D., Madden, K., Zhao, A., Auyeung, K., Levander, O.A., Finkelman, F., Urban Jr, J.F., Shea Donohue, P.T. 2004. Selenium (se) and vitamin E (ve) deficiencies impair intestinal function and result in persistent infection with heligmosomoides polygyrus [abstract]. Federation of American Society of Experimental Biology Journal. 18(4):A9.
STUDY OF THE EFFECT OF COPPER DEFICIENCY ON CVB3/0 AND CVB3/20 INFECTIONS: THE LIGHT MICROSCOPIC EVALUATION OF THE PANCREATA AND HEARTS OF C3H/HEJ MICE - (Abstract)
Nelva, B., Levander, O.A., Hines, F., Smith, A.D. 2004. Study of the effect of copper deficiency on cvb3/0 and cvb3/20 infections: The light microscopic evaluation of the pancreata and hearts of c3h/hej mice [abstract]. Toxicologic Pathology. 32(1):146.

   
 
Last Modified: 11/04/2008
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