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Biomarker Core

EPA Grant Number: R827355C010
Subproject: this is subproject number 010 , established and managed by the Center Director under grant R827355
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).

Center: Airborne PM - Northwest Research Center for Particulate Air Pollution and Health
Center Director: Koenig, Jane Q.
Title: Biomarker Core
Investigators: Kalman, Dave , Dills, Russell , Katz, Bethany , Paulsen, Michael , Simpson, Chris
Current Investigators: Kalman, Dave , Dills, Russell , Simpson, Chris
Institution: University of Washington
EPA Project Officer: Stacey Katz/Gail Robarge,
Project Period: June 1, 1999 through May 31, 2004 (Extended to May 31, 2006)
RFA: Airborne Particulate Matter (PM) Centers (1999)
Research Category: Particulate Matter

Description:

Objective:

The objective of this research project is to develop analytical methods for the determination of organic tracers of woodsmoke, and polycyclic aromatic hydrocarbon (PAH) contribution to particulate matter (PM) in urine and isoprostanes in urine and breath.

Publications and Presentations:

Publications have been submitted on this subproject: View all 19 publications for this subprojectView all 191 publications for this center

Journal Articles:

Journal Articles have been submitted on this subproject: View all 12 journal articles for this subprojectView all 94 journal articles for this center

Supplemental Keywords:

air pollution, air pollutants, particulate matter, PM, polycyclic aromatic hydrocarbons, PAHs, isoprostanes in urine, isoprostanes in breath, woodsmoke, organic tracers, methoxyphenols, levoglucosan, Seattle, Washington, WA, indoor exposure, outdoor exposure, biomarker, urinary methoxyphenol biomarker, high biomass smoke, dithiothreitol assay, oxidative potential of PM, ELISA, isoprostanes, health effects, fine particles. , ENVIRONMENTAL MANAGEMENT, Air, Geographic Area, Scientific Discipline, Health, RFA, PHYSICAL ASPECTS, Susceptibility/Sensitive Population/Genetic Susceptibility, Toxicology, Risk Assessment, Risk Assessments, Air Pollutants, genetic susceptability, Northwest, Health Risk Assessment, Physical Processes, Epidemiology, Air Pollution Effects, air toxics, Atmospheric Sciences, Biochemistry, particulate matter, Environmental Chemistry, State, aerosols, exposure assessment, California (CA), exposure and effects, environmental hazard exposures, ambient air quality, cardiovascular disease, health effects, inhalation, mortality, epidemelogy, air quality, cardiopulmonary response, hazardous air pollutants, atmospheric aerosols, cardiopulmonary responses, human health risk, particle exposure, toxics, mortality studies, biomarker based exposure inference, acute cardiovascular effects, biostatistics, dose-response, human health effects, particulates, sensitive populations, ambient particle health effects, air pollution, atmospheric chemistry, exposure, biomarker, human susceptibility, ambient aerosol, health risks, human exposure, Human Health Risk Assessment, morbidity

Progress and Final Reports:
2002 Progress Report
2003 Progress Report
Final Report


Main Center Abstract and Reports:
R827355    Airborne PM - Northwest Research Center for Particulate Air Pollution and Health

Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R827355C001 Epidemiologic Study of Particulate Matter and Cardiopulmonary Mortality
R827355C002 Health Effects
R827355C003 Personal PM Exposure Assessment
R827355C004 Characterization of Fine Particulate Matter
R827355C005 Mechanisms of Toxicity of Particulate Matter Using Transgenic Mouse Strains
R827355C006 Toxicology Project -- Controlled Exposure Facility
R827355C007 Health Effects Research Core
R827355C008 Exposure Core
R827355C009 Statistics and Data Core
R827355C010 Biomarker Core
R827355C011 Oxidation Stress Makers

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.


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