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Research Project:
BT MODE OF ACTION IN COLEOPTERAN PESTS
Location: Biological Research
Project Number: 5430-43000-026-06
Project Type:
Nonfunded Cooperative Agreement
Start Date: Jan 02, 2007
End Date: Jan 02, 2009
Objective:
To identify and characterize proteins in the midgut of coleopteran pests that interact with coleopteran-specific Bacillus thuringiensis toxins, so that the efficacy and host range of coleopteran-specific Bt toxins can be expanded in storage pest control.
Approach:
We will use a proteomics and genomics approach to identify proteins in the coleopteran midgut that interact with Bt toxins. Techniques include 1- and 2-D SDS Page analysis, MALDI-TOF and MS/MS, immunoprecipitation, RNAi, microarray analysis, and genetic cloning and engineering.
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Last Modified: 11/08/2008
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