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Organophosphate Pesticides

This subject was discussed at the following meeting(s):

June 26-27, 2002: Determination of the Appropriate FQPA Safety Factor(s) in the Organophosphorus Pesticide Cumulative Risk Assessment: Susceptibility and Sensitivity to the Common Mechanism, Acetylcholinesterase Inhibitions

Final Report (PDF) (30 pp, 214K, About PDF)
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February 5-8, 2002: Organophosphate Pesticides: Preliminary OP Cumulative Risk Assessment

Final Report (PDF) (94 pp, 203K, About PDF)
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September 5-6, 2001: Preliminary Cumulative Hazard and Dose-response Assessment for Organophosphorus Pesticides: "Determination of Relative Potency and Points of Departure for Cholinesterase Inhibition"

Final Report
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September 26-29, 2000: Test Guidelines for Chronic Inhalation Toxicity and Carcinogenicity of Fibrous Particles; Cumulative Hazard Assessment of Organophosphorus Pesticides; Components and Methodologies of the Calendex™, Lifeline™, and REx Models as Tools for Dietary and Residential Pesticide Exposure and Risk Assessments; and Assessment of Pesticide Concentrations in Drinking Water and Water Treatment Effects on Pesticide Removal and Transformation

Final Reports

Session I - Test Guidelines for Chronic Inhalation Toxicity and Carcinogenicity of Fibrous Particles (PDF) (25 pp, 106K, About PDF)

Session II End Point Selection And Determination Of Relative Potency In Cumulative Hazard Assessment: A Pilot Study Of Organophosphorus Pesticide Chemicals (PDF) (34 pp, 210K, About PDF)

Sessions III-V (PDF) (35 pp, 80K, About PDF)

Session VI -Progress Report on Estimating Pesticide Concentrations in Drinking Water and Assessing Water Treatment Effects on Pesticide Removal and Transformation: A Consultation (PDF) (24 pp, 65K, About PDF)

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August 17-18, 2000: Assessment of Human Carcinogenic Potential of Malathion

Final Report (PDF) (21 pp, 52K, About PDF)
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December 7-8, 2000: Case Study of the Cumulative Risk of 24 Organophosphate Pesticides; Cumulative Risk Assessment Method for Dietary (Food) Exposure; Cumulative Risk Assessment for Residential Exposure; Cumulative Risk Assessment for Drinking Water; Integrated Cumulative Risk Assessment

Final Report (PDF) (41 pp, 94K, About PDF)
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March 24-25, 1998: Common Mechanism of Action of Organophosphates, Policy for Review of Monte Carlo Analysis for Dietary and Residential Exposure Scenarios, Suggested Probabilistic Risk Assessment Methodology for Evaluating Pesticides that exhibit a Common Mechanism of Action, Use of FQPA 10x Safety Factor to Address Special Sensitivity of Infants and Children to Pesticides, and Post Application Exposure Guidelines

Final Report
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March 19-20, 1997: Toxicology Endpoint Selection Process; Inhalation Risk Assessments and the Combining of Margin of Exposures; Aggregate Exposure Methodology Issues; Common Mechanism of Action; Visual System Toxicity Testing of Organophosphates

Final Report (PDF) (35 pp, 167K, About PDF)
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