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Research Project: IDENTIFICATION, VALIDATION AND FINE-MAPPING OF QUANTITATIVE TRAIT LOCI IN DAIRY CATTLE

Location: Bovine Functional Genomics

Publications

Mapping of quantitative trait loci controlling tick [Riphicephalus (Boophilus) microplus] resistance on bovine cjrp,psp,es 5, 7 and 14 - (Peer Reviewed Journal)
Gasparin, G., Miyata, L.L., Coutinho, L.L., Martinez, M.L., Teodoro, R.L., Furlong, J., Machado, M.A., Silva, M.V., Campos, A.L., Sonstegard, T.S., Regitano, L.C. 2007. Mapping of quantitative trait loci controlling parasite resistance in a F2 experimental bovine population. Animal Genetics. 38(5):453-459.
Creation of a Gene Atlas in cattle using sequence-based transcriptional profiling - (Abstract)
Sonstegard, T.S., Keele, J.W., Harhay, G.P., Smith, T.P., Matukumalli, L.K., Van Tassell, C.P., Liu, G., Alexander, L.J. 2007. Creation of a Gene Atlas in cattle using sequence-based transcriptional profiling. [abstract] Joint Abstracts of the American Dairy Science and Society of Animal Science.
Applied bovine genomics: New opportunities for managing disease and intensifying production - (Proceedings/Symposium)
Sonstegard, T.S., Matukumalli, L.K., Gasbarre, L.C., Silva, M.V., Van Tassell, C.P. 2007. Applied bovine genomics: New opportunities for managing disease and intensifying production. [abstract]. Meeting Proceedings.
Discovery and Profiling of Bovine Micrornas from Immune Related and Embryonic Tissues - (Peer Reviewed Journal)
Coutinho, L.L., Matukumalli, L.K., Sonstegard, T.S., Van Tassell, C.P., Gasbarre, L.C., Capuco, A.V., Smith, T.P. 2007. Discovery and profiling of bovine micrornas from immune related and embryonic tissues. Physiological Genomics. 29(1):35-43.
A second generation radiation hybrid map to aid the assembly of the bovine genome sequence - (Peer Reviewed Journal)
Jann, O.C., Aerts, J., Jones, M., Hastings, N., Law, A., Mckay, S., Marques, E., Prasad, A., Yu, J., Moore, S.S., Florita, S., Mahe, M., Eggen, A., Silveri, L., Negrini, R., Milanesi, E., Ajmone-Marsan, P., Vakebtubu, A., Marchitelli, C., Janitz, M., Herwig, R., Hennig, S., Savarese, M., Gorni, C., Connor, E.E., Sonstegard, T.S., Smith, T.P., Drogemuller, C., Williams, J. 2006. A second generation radiation hybrid map to aid the assembly of the bovine genome sequence. BMC Genomics. 7:283-298.
Qtl Mapping for Birth Weight on Bovine Chromosome 14 - (Peer Reviewed Journal)
Miyata, M., Gasparin, G., Coutinho, L.L., Martinez, M.L., Machado, M.A., Da Silva, M.V., Campos, A.L., Sonstegard, T.S., Do Rosario, M.F., Regitano, L.C. 2007. Quantitative trait loci (QTL) mapping for birth weight on bovine chromosome 14. Genetics and Molecular Biology, Vol 30, No.2, pp 364-369.
Estimates of Genetic Parameters Using Random Regression Models for Gastrointestinal Helminthoid Data in Angus Cattle - (Peer Reviewed Journal)
Silva, M.V., Van Tassell, C.P., Sonstegard, T.S., Cobuci, J.A., Gasbarre, L.C. 2006. Estimates of genetic parameters using random regression models for gastrointestinal helminthoid data in angus cattle. World Congress of Genetics Applied in Livestock Production. 8:15-34.
Estimates of Genetic Parameters Using Random Regression Models for Gastrointestinal Helminthoid Data in Cattle - (Proceedings/Symposium)
Silva, M.V., Van Tassell, C.P., Sonstegard, T.S., Cobuci, J.A., Gasbarre, L.C. 2006. Estimates of genetic parameters using random regression models for gastrointestinal helminthoid data in cattle. Brazilian Animal Science Society. CD-Rom - MEL036. pp. 105.
Detection of a QTL associated with tick resistance on bovine chromosome 7 (BTA7) using a F2 experimental population - (Proceedings/Symposium)
Gasparin, G., Miyata, M., Coutinho, L.L., Martinez, M.L., Machado, M.A., Silva, M., Campos, A.L., Sonstegard, T.S., Regitano, L. 2006. Detection of a QTL associated with tick resistance on bovine chromosome 7 (BTA7) using a F2 experimental population. Proceedings of 8th World Congress of Genetics Applied in Livestock Production 8(21-15):1-4.
A Qtl for Resistance to Boophilus Microplus Maps to Bovine Chromosome 14 - (Proceedings/Symposium)
Regitano, L., Miyata, M., Gasparin, G., Coutinho, L.L., Martinez, M.L., Machado, M.A., Silva, M., Campos, A.L., Sonstegard, T.S. 2006. A QTL for resistance to Boophilus microplus maps to bovine chromosome 14. Proceedings of 8th World Congress of Genetics Applied in Livestock Production 8(15-32):1-4.
Use of Box-Cox Transformation in Analysis of Fecal Egg Count Data - (Peer Reviewed Journal)
Sonstegard, T.S., Marcos, D., Gasbarre, L.C., Van Tassell, C.P. 2006. Use of box-cox transformation in analysis of fecal egg count data. World Congress of Genetics Applied in Livestock Production. 8(15-35):1-4.
Comprehensive Search of Bovine Micrornas Expressed in Immune and Gut Tissues by Deep Sequencing - (Abstract)
Sonstegard, T.S., Matukumalli, L.K., Coutinho, L.L., Liu, G., Gasbarre, L.C., Smith, T.P. 2006. Comprehensive search of bovine micrornas expressed in immune and gut tissues by deep sequencing [abstract]. International Conference on Animal Genetics. pp. C354.
Identification and Profiling of Bovine Micrornas from Immune Related and Embryonic Tissues. - (Abstract)
Coutinho, L.L., Matukumalli, L.K., Sonstegard, T.S., Van Tassell, C.P., Gasbarre, L.C., Capuco, A.V., Smith, T.P. 2006. Identification and profiling of bovine micrornas from immune related and embryonic tissues [abstract]. 17th Annual BARC Poster Day, Beltsville, MD. No 6.
Detection of Quantitatiave Trait Loci Affecting Growth and Reproductive Traits in Bos Indicus Beef Cattle (Nellore) - (Abstract)
Avelar, G.A., Neto, L.R., Teixeira, L.A., Sonstegard, T.S., Van Tassell, C.P., Garcia, J.F. 2006. Detection of quantitatiave trait loci affecting growth and reproductive traits in bos indicus beef cattle (nellore) [abstract]. Animal Genetics International Conference Proceedings. pp 180.
High Density Ests Based Bovine Physical Maps and Their Use to Construct Comparative Maps and Inform the Bovine Genome Sequence Assembly - (Abstract)
Williams, J.L., Aerts, J., Law, A., Jann, O., Janitz, M., Hennig, S., Eggen, A., Floriot, S., Ajmone-Marsan, P., Milanse, E., Valentini, A., Marchitelli, C., Mckay, S., Prasad, A., Yu, J., Moore, S.S., Drogemuller, C., Connor, E.E., Sonstegard, T.S., Stone, R.T., Smith, T.P. 2006. High density ESTs based bovine physical maps and their use to construct comparative maps and inform the bovine genome sequence assembly[abstracat]. Plant and Animal Genome XIV:55. Number W214.
Towards Identification of the Genetic Control of Resistance to Gastrointestinal Helminth Infections in Sheep and Mice. - (Abstract)
Iraqi, F.A., Mugambi, J.M., Sonstegard, T.S., Garcia, F.J., Van Tassell, C.P., Hanotte, O., Nagda, S., Wakelin, D., Gibson, J.P., Behnke, J.M., Baker, L.R. 2005. Towards identification of the genetic control of resistance to gastrointestinal helminth infections in sheep and mice. Fourth All African Conference on Animal Agriculture. Tanzania, Abstract 45.
Identification of Quantitative Trait Loci Affecting Parasite Indicator Traits in a Double Backcross Population of Sheep. - (Abstract)
Sonstegard, T.S., Iraqi, F., Mugambi, J., Van Tassell, C.P., Garcia, F., Hanotte, O., Nagda, S., Gibson, J., Baker, L. 2005. Identification of quantitative trait loci affecting parasite indicator traits in a double backcross population of sheep. [abstract]. ADSA/ASAS Joint Meeting, Minneapolis, MN, number 252.
Fetal Losses and Pathologic Findings of Clones Derived from serum-Starved Versus Serum-Fed Bovine Ovarian Granulosa Cells. - (Peer Reviewed Journal)
Lawrence, J.L., Schrick, F., Hopkins, F.M., Welborn, M.G., Mccracken, M.D., Sonstegard, T.S., Wilson, T.J., Edwards, J. 2005. Fetal losses and pathologic findings of clones derived from serum-starved versus serum-fed bovine ovarian granulosa cells. Reproductive Biology. 5(2):171-184.
Characterization of Fezl Effects on Scs in a Sample of North American Holsteins - (Abstract)
Sonstegard, T.S., Van Tassell, C.P. 2005. Characterization of fezl effects on scs in a sample of north american Holsteins [abstract]. ADSA/ASAS Joint Meeting. p. 248.
Whole Genome Scan to Detect Qtl for Milk Production, Conformation and Functional Traits in Two U.S. Holstein Families - (Peer Reviewed Journal)
Schnabel, R.D., Sonstegard, T.S., Taylor, J.F., Ashwell, M.S. 2005. Whole genome scan to detect QTL for milk production, conformation and functional traits in two U.S. Holstein families. Animal Genetics. 36(5):408-416.
Characterization of the Infection-Responsive Bovine Lactoferrin Promoter - (Peer Reviewed Journal)
Zheng, J., Ather, J.L., Sonstegard, T.S., Kerr, D.E. 2005. Characterization of the infection-responsive bovine lactoferrin promoter. Gene. 353:107-17.
Comparative Mapping of Bovine Chromosome 27 with Human Chromosome 8 Near a Dairy Form Qtl in Cattle - (Peer Reviewed Journal)
Connor, E.E., Ashwell, M.S., Schnabel, R., Williams, J.L. 2006. Comparative mapping of bovine chromosome 27 with human chromosome 8 near a dairy form QTL in cattle. Cytogenetics and Genome Research. 112:98-102.
Fine-Mapping Milk Production Quantitative Trait Loci on Bta6: Analysis of the Bovine Osteopontin Gene. - (Peer Reviewed Journal)
Schnabel, R.D., Jong-Joo, K., Ashwell, M.S., Sonstegard, T.S., Van Tassell, C.P., Connor, E.E., Taylor, J.F. 2005. Fine-mapping milk production quantitative trait loci on bta6: analysis of the bovine osteopontin gene. Proceedings of the National Academy of Sciences. 102:6896-6901.
Immunogenomics and the Transition Dairy Cow: Physiological Insights and Future Possibilities for Improving Animal Health. - (Abstract)
Burton, J.L., Madsen, S.A., Chang, L.C., Weber, P.S., Coussens, P.M., Rosa, G., Matukumalli, L.K., Sonstegard, T.S., Smith, T.P. 2005. Immunogenomics and the transition dairy cow: physiological insights and future possibilities for improving animal health. ADSA/ASAS Joint Meeting, Cincinnati, OH, Abstract 17
Expression Profiles and Snp Analysis of Genes That Regulate Neutrophil Apoptosis, Endothelial Adhesion, and Extracellular Matrix Remodeling at Parturition in Dairy Cows - (Abstract)
Burton, J.L., Madsen, S.A., Chang, L., Weber, P.S., Rosa, G.J., Matukumalli, L.K., Sonstegard, T.S. 2005. Expression profiles and snp analysis of genes that regulate neutrophil apoptosis, endothelial adhesion, and extracellular matrix remodeling at parturition in dairy cows. Plant and Animal Genome XIII,204, pp. 694. San Diego, CA [Abstract].
Fine-Mapping Milk Production Qtl on Bta6: Analysis of the Bovine Osteopontin Gene - (Abstract)
Schnabel, R.D., Ashwell, M.S., Sonstegard, T.S., Connor, E.E., Van Tassell, C.P., Kim, J., Taylor, J.F. 2005. Fine-mapping milk production qtl on bta6: analysis of the bovine osteopont [abstract]. Plant and Animal Genome XIII. p. 532.
Alignment Genomes Across Species - (Abstract)
Williams, J.L., Hastings, N., Jann, O., Law, A., Stone, R.T., Snelling, W.M., Connor, E.E., Sonstegard, T.S., Smith, T.P. 2005. Alignment genomes across species [abstract]. Plant and Animal Genome XVII. p. 241.
Physical Mapping of Eif4ebp1 and Leprotl1 Genes in Cattle - (Germplasm Release)
Connor, E.E. 2004. Physical mapping of eif4ebp1 and leprotl1 genes in cattle. Germplasm Release. Accession numbers BV209032-BV209035.
Sequencing and Mapping of the Bovine Thyroid Hormone Response Element (Spot14) Gene - (Germplasm Release)
Sonstegard, T.S., Connor, E.E. 2004. Sequencing and mapping of the bovine thyroid hormone response element (spot14) gene. Germplasm Release. Accession number AY656814.
Bovine Bac End Sequences from Rpci-42 Library - (Germplasm Release)
Aycock, M.M., Najar, F.Z., Gasbarre, L.C., Van Tassell, C.P., Sonstegard, T.S., Connor, E.E., Capuco, A.V., Roe, B.A. 2004. Bovine bac end sequences from rpci-42 library. Germplasm Release.
Sequence Analysis of Ests Unique to the Bos Taurus Gene Index - (Germplasm Release)
Connor, E.E., Sonstegard, T.S., Van Tassell, C.P., Matukumalli, L.K. 2004. Sequence analysis of ests unique to the bos taurus gene index. Germplasm Release. Accession numbers CN779616-CN779642.
Production of Est from Cdna Libraries Derived from Immunologically Activated Bovine Abomasum - (Germplasm Release)
Sonstegard, T.S., Van Tassell, C.P., Matukumalli, L.K., Harhay, G.P., Bosak, S., Rubenfield, M., Gasbarre, L.C. 2004. Production of est from cdna libraries derived from immunologically activated bovine abomasum. Germplasm Release.
Production of Est from Cdna Libraries Derived from Immunologically Activated Bovine Small Intestine - (Germplasm Release)
Sonstegard, T.S., Van Tassell, C.P., Matukumalli, L.K., Harhay, G.P., Bosak, S., Rubenfield, M., Gasbarre, L.C. 2004. Production of est from cdna libraries derived from immunologically activated bovine small intestine. Germplasm Release.
Bovine Genomics Update: Making a Cow Jump over the Moon - (Review Article)
Sonstegard, T.S., Van Tassell, C.P. 2004. Bovine genomics update: making a cow jump over the moon. Genetical Research 84, pp. 3-9.
An Expanded Comparative Map of Bovine Chromosome 27 Targeting Dairy Form Qtl Regions - (Peer Reviewed Journal)
Connor, E.E., Sonstegard, T.S., Ashwell, M.S., Bennett, G.L., Williams, J.L. 2004. An expanded comparative map of bovine chromosome 27 targeting dairy form QTL regions. Animal Genetics. 35:265-269.
Detection of Quantitative Trait Loci Affecting Conformation Traits in Holstein Cattle - (Abstract)
Ashwell, M.S., Heyen, D.W., Sonstegard, T.S., Van Tassell, C.P., Lewin, H.A. 2005. Detection of quantitative trait loci affecting conformation traits in holstein cattle [abstract]. American Dairy Science Association.
Long Days Do Not Alter Mammary Growth in Prepubertal Heifers - (Abstract)
Connor, E.E., Rius, A.G., Auchtung, T.L., Wood, D.L., Kendall, P.E., Dahl, G.E., Capuco, A.V. 2004. Long days do not alter mammary growth in prepubertal heifers [abstract]. Journal of Animal Science Supplement. 82(Suppl. 1): 206.
Use of Serial Analysis of Gene Expression (Sage) for Gene Transcript Profiling in Lactating Bovine Mammary Gland - (Abstract)
Connor, E.E., Capuco, A.V., Sonstegard, T.S. 2004. Use of serial analysis of gene expression (sage) for gene transcript profiling in lactating bovine mammary gland [abstract]. Journal of Animal Science Supplement. 82(Suppl. 1):131.
Long Days That Hasten Puberty Do Not Reduce Lean Body Growth in Heifers - (Abstract)
Rius, A.G., Kendall, P.E., Auchtung, T.L., Capuco, A.V., Connor, E.E., Dahl, G.E. 2004. Long days that hasten puberty do not reduce lean body growth in heifers. Abstract. Joint Abstracts of the American Dairy Science and Society of Animal Science, p. 500.
Chromosomal Mapping of 12 Gene-Associated Markers in Cattle Identifies Novel Regions of Conserved Synteny Between the Human and Bovine Gen0mes - (Proceedings/Symposium)
Connor, E.E., Sonstegard, T.S., Ashwell, M.S., Bennett, G.L., Williams, J.L. 2004. Chromosomal mapping of 12 gene-associated markers in cattle identifies novel regions of conserved synteny between the human and bovine genomes. Plant and Animal Genome XII:228. Abstract P630.
Comparative Mapping of a Chromosomal Region Associated with a Conformational Trait Locus in Dairy Cattle - (Germplasm Release)
Connor, E.E., Sonstegard, T.S., Ashwell, M.S., Matukamalli, L.K., Philpot, J.C., Shade, L.L., Bennett, G.L., Williams, J.L. 2003. Comparative mapping of a chromosomal region associated with a conformational trait locus in dairy cattle. Germplasm Release. Accession numbers. CG695835-CG699931, CG706319-CG706518, BV096721-BV096734.
Using Host Genomics to Control Nematode Infections - (Abstract)
GASBARRE, L.C., SONSTEGARD, T.S., VAN TASSELL, C.P., PADILHA, T. USING HOST GENOMICS TO CONTROL NEMATODE INFECTIONS. World Association for the Advancement of Veterinary Parasitology. pp. 119, 2003.
Molecular Cloning, Sequencing, and Sequence Analysis of Bovine Lactoferrin 5' Flanking Region - (Germplasm Release)
Zheng, J., Ather, J.L., Sonstegard, T.S., Kerr, D.E. 2003. Molecular cloning, sequencing, and sequence analysis of bovine lactoferrin 5' flanking region. Genbank.
Characterization of Orestes Cdna Libraries Generated from Mammary Gland Tissues of Holstein (Bos Taurus) and Gir (Bos Indicus) Cattle. - (Abstract)
Mota, A.F., Sonstegard, T.S., Van Tassell, C.P., Shade, L.L., Matukumalli, L., Wood, D.L., Capuco, A.V., Brito, M.A., Martinez, M.L., Connor, E.E. 2003. Characterization of ORESTES cDNA libraries generated from mammary gland tissues of Holstein (Bos taurus) and Gir (Bos indicus) cattle [abstract]. Animal Production World Conference Proceedings.
Physical and Linkage Mapping of Mammary-Derived Expressed Sequence Tags in Cattle. - (Peer Reviewed Journal)
Connor, E.E., Sonstegard, T.S., Keele, J.W., Bennett, G.L., Williams, J.L., Papworth, R., Van Tassell, C.P., Ashwell, M.S. 2004. Physical and lindage mapping of mammary-derived expressed sequence tags (EST) in cattle. Genomics. vol. 83, pp.148-152.
Ontogenetic Regulation of Progesterone Receptor (Pr) Expression in Bovine Mammary Gland - (Abstract)
Connor, E.E., Capuco, A.V., Wood, D.L., Sonstegard, T.S., Mota, A.F. 2003. Ontogenetic regulation of progesterone receptor (pr) expression in bovine mammary gland [abstract]. Journal of Animal Science Supplement. 81 (Suppl. 1): 302.
Quantitative Analysis of Estrogen-Related Receptor A, Estrogen Receptor a and Estrogen Receptor B Throughout Bovine Mammary Gland Development - (Abstract)
Connor, E.E., Capuco, A.V., Sonstegard, T.S., Mota, A.F., Wood, D.L., Garrett, W.M., Bennett, G.L., Williams, J.L. 2003. Quantitative analysis of estrogen-related receptor a, estrogen receptor a and estrogen receptor b throughout bovine mammary gland development [abstract]. Journal of Animal Science Supplement. 81 (Suppl. 1):118.
Detection of Quantitative Trait Loci Affecting Milk Production, Health, and Reproductive Traits in Holstein Cattle - (Peer Reviewed Journal)
Ashwell, M.S., Heyen, D.W., Sonstegard, T.S., Van Tassell, C.P., Da, Y., Van Raden, P.M., Ron, M., Weller, J.I., Lewin, H.A. 2004. Detection of quantitative trait loci affecting milk production,health, and reproductive traits in Holstein cattle. Journal of Dairy Science. vol. 87(2): pp. 468-75.
Genetic Diversity and Background Linkage Disequilibrium in North American Holstein Cattle Population - (Peer Reviewed Journal)
VALLEJO, R.L., LI, Y.L., ROGERS, G.W., ASHWELL, M.S. GENETIC DIVERSITY AND BACKGROUND LINKAGE DISEQUILIBRIUM IN NORTH AMERICAN HOLSTEIN CATTLE POPULATION. JOURNAL OF DAIRY SCIENCE 020639.R2, 2003.
Characterization of Immune Response Gene Expression Patterns in Cattle Selected for Resistance Or Suscptibility to Gastrointestinal Parasites. - (Abstract)
Sonstegard, T.S., Araujo, R.N., Zarlenga, D.S., Padilha, T., Lima, W.S., Nascimento, E., Gasbarre, L.C. 2003. Characterization of immune response gene expression patterns in cattle selected for resistance or suscptibility to gastrointestinal parasites. Meeting Abstract.
The Bovine Type I 5'-Deiodinase (Dio1) Gene Maps to Chromosome 3 - (Research Notes)
CONNOR, E.E., SONSTEGARD, T.S., KAHL, S., BENNETT, G.L., SNELLING, W.M. THE BOVINE TYPE I 5'-DEIODINASE (DIO1) GENE MAPS TO CHROMOSOME 3. ANIMAL GENETICS. vol. 34, pp. 232-240, 2003.
Sequencing of Expressed Sequence Tags (Ests) Unique to the Bos Taurus Gene Index - (Germplasm Release)
Connor, E.E., Sonstegard, T.S., Van Tassell, C.P. 2002. Sequencing of expressed sequence tags (ests) unique to the bos taurus gene index. Germplasm Release. Accession Numbers CA923315-CA923384.
Mapping of Gene-Associated Sequence Tagged Sites (Stss) to the Bovine Linkage and Radiation Hybrid Maps - (Germplasm Release)
Connor, E.E., Sonstegard, T.S., Keele, J.W., Bennett, G.L., Williams, J., Papworth, R., Van Tassell, C.P., Ashwell, M.S. 2003. Mapping of gene-associated sequence tagged sites (stss) to the bovine linkage and radiation hybrid maps. Germplasm Release. Accession Numbers BV005755-BV005814.
Linkage Mapping of Bovine Type I 5' Deiodinase Gene (Dio1) - (Germplasm Release)
Connor, E.E., Sonstegard, T.S., Kahl, S., Bennett, G.L., Snelling, W.M. 2003. Linkage mapping of bovine type i 5' deiodinase gene (dio1). Germplasm Release. Accession Numbers BV005735-36.

   

 
Project Team
Sonstegard, Tad
Li, Robert
Van Tassell, Curtis - Curt
 
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Last Modified: 05/14/2009
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