|
|
Funding Agency:
Department of Veterans Affairs (VA)
On-going Research Projects:
This project will study how amyotrophic lateral sclerosis (ALS) develops in mice.
This study will interview and examine groups of Gulf War veterans with and without unexplained illnesses, in order to determine whether abnormalities in the brain imaging of Gulf War veterans occur independently of posttraumatic stress disorder, alcohol dependence and depression.
This study will review how stress may effect memory.
These animal projects will study potential causes of nervous system diseases such as amyotrophic lateral sclerosis (ALS), Parkinson's disease, and Alzheimer's disease.
This project will study how leishmaniasis infects the cells of the body.
This study will review the effects of mental trauma on normal brain functioning in women with post-traumatic stress disorder.
This project will determine if Risperidone reduces PTSD symptoms, relative to a placebo, in veterans with military service related chronic PTSD who have been partial or non-responders to antidepressant medications.
This animal study will look at the potential role of chemical changes in the body as they might lead to amyotrophic lateral sclerosis (ALS).
This group of projects will look at new ways to development treatments for diseases like amyotrophic lateral sclerosis (ALS).
This study will test the ability to deliver cognitive-behavioral techniques (CBT) over the telephone.
Completed Research Projects:
This study tracked the health status of Gulf War veterans over a five-year period.
This study tested the ability of magnetic fields to treat individuals with depression.
This study tested individuals from reserve units involved in Operation Desert Storm for symptoms related to post-traumatic stress disorder.
This study compared the ability of two types of treatment for mental and emotional disorders for women with military-related posttraumatic stress disorder.
This project studied Gulf War veterans who had unexplained chronic medical symptoms such as pain, fatigue, and/or cognitive difficulties.
This study was designed to determine whether or not veterans are at an increased risk of amyotrophic lateral sclerosis mortality.
This study measured levels of three enzymes among Gulf War deployed and era veterans to determine if mood and anxiety disorders are related to these enzymes.
This study was an epidemiologic investigation into the occurrence of ALS (Lou Gehrig's disease) among veterans of the Gulf War.
This study was designed to evaluate the brain functions in patients with post-traumatic stress disorder.
This study tested whether a 12-month course of doxycycline treatment in deployed mycoplasma-positive Gulf War veterans could improve functional status.
This study looked at combat veterans to determine if prior combat experience lead to learning and memory loss.
This project studied how the brain's connections to intestine functions may lead to chronic pain in the midsection.
These studies attempted to develop a sensitive test to detect ALS early.
This study compared the treatment and patient statisfaction between Primary Care Clinics and Gulf War Special Emphasis Clinics.
The primary purpose was to support pilot projects focused on Gulf War veterans health issues.
This series of studies were conducted by the Boston Environmental Hazards Research Center, which is located at the Boston VA Medical Center. The studies focused on environmental health, neuroscience, and neurocognitive methodologies related to the health of Gulf War veterans.
This project studied how low blood pressure may contribute to chronic fatigue in Gulf War veterans.
This study tested new approaches to health care delivery for Gulf War veterans suffering from undiagnosed and ill-defined illnesses and disability.
This project was designed to determine the cause of abdominal pain and diarrhea experienced by a subset of Gulf War veterans.
This project reviewed potential treatments for irritable bowel syndrome (IBS).
This study investigated how the brain shifts between sleep and wakefulness.
This study surveyed a sample of Gulf War veterans from a National Guard unit and found these veterans were more likely to report a variety of digestive problems than non-deployed members from the same unit.
This project was designed to develop a blood test for leishmaniasis and determine the number of Gulf War veterans infected.
This study reviewed the relationship between Gulf War service and the development of fibromyalgia.
This was a multi-year study to evaluate the relationships between exposures and unexplained illnesses in Gulf War veterans.
This study was designed to evaluate the effects of repeated exposures to various chemicals and noise on body functions and behaviors of Gulf War veterans.
This study evaluated the long-term effects of chemical weapon exposure on nervous and non-nervous system tissue.
This demonstration project was to measure the treatment's ability to successfully help Gulf War veterans with multiple physical symptoms.
This project examined patterns of readjustment of Gulf War veterans following their return from the Gulf region.
The purpose of this study was to develop a checklist to compare past exposure to chemical substances to current medical disorders.
This study utilized adult rats to assess changes in brain function and gene expression after exposure to alcohol.
This study compared patients with irritable bowel syndrome to patients with diarrhea that suddenly began while serving in the Persian Gulf.
This study included several projects related to disorders (seizures, psychiatric, and behavioral) affecting thousands of veterans.
The objective of this study was to determine whether vulnerability to environmental exposure may result from defects in the expression of certain gene products.
This animal project studied whether mice with a certain gene variation were more sensitive to exposures.
This project reviewed the effects of stress and pyridostigmine bromide on rats.
The primary purpose of this core project was to provide support to VA projects (VA-5A through VA-5D) concerned with Gulf War veterans health issues.
This project's aim was to test the effects of exposure to diesel fumes and physical stress on Persian Gulf War Veterans.
This animal project was to determine if genetic vulnerability to stress increased the effects of exposures to pyridostigmine bromide and oil well fires.
This project reviewed cancer registries in several states to determine whether or not there is an increase cancer risk associated with the 1991 Gulf War.
This project evaluated cognitive, social and behavoiral functioning among Gulf War veterans experiencing health problems after their return.
This project reviewed self-reported health complaints and environmental exposures in the Persian Gulf region.
This project evaluated central nervous system functioning in returning Gulf War veterans.
This study aimed to determine the relationship between respiratory illness and exposure to oil well fires in Gulf War veterans.
This project attempted to increase the understanding of chronic multisymptom illness (CMI).
This project was designed to begin looking at new treatment methods for leishmaniasis.
The primary goal of this study was to examine the relationship between fibromyalgia and mental disorders within families.
This study was done to determine if it was possible to follow up on soldiers exposed to chemical agents.
The purpose of this study was to continue to examine mental illness and brain function in Gulf War veterans with and without PTSD.
This study used a brain scan to examine the brain activities of Gulf War veterans with unexplained pain.
This study looked at ways to examine the effects of lead on brain function and behavior in adults.
This study conducted gene expression and protein characterization of brain tissue collected post-mortem from subjects with schizophrenia, bipolar disorder and major depression.
This project reviewed the potential relationship between Gulf War illness and PTSD.
This study examined the pattern of cancer cases in Gulf War and Vietnam veterans from New England.
Not available.
This study was designed to evaluate the brain functions in men and women with chronic post-traumatic stress disorder.
The project's aim was to survey some Persian Gulf War veterans to determine risk factors and their relationships to symptoms that could represent health problems for Gulf War Veterans.
This study reviewed how the brain regulates natural sleep and waking.
This program established a research center to evaluate, recognize and treat sleep disorders of Gulf War veterans.
This study evaluated changes in the immune system of Gulf War veterans to determine if those changes contributed to unexplained illness in these veterans.
This project established innovative clinical programs for Gulf War veterans in the VA medical centers Portland and Seattle.
This study reviewed the impact of a low-intensity care management program on outcomes of patients with major depression.
This animal study tested several therapies for the treatment of brain and spinal cord cancers.
This animal study tested the effects of stress and pyriodstigmine bromide on rats.
This animal study compared the relationship between reflexes and learned responses after PB had been given.
This project studied the potential of stem cells in treating amyotrophic lateral sclerosis (ALS).
This project compared two groups of PTSD sufferers (one Vietnam-era, one Gulf War era) to a group of veterans with no PTSD symptoms.
This study compared death rates in Gulf War veterans to veterans who did not serve in the Gulf.
This study compared joint pain and swelling symptoms reported by Gulf War veterans to veterans of other deployments.
This study compared a number of symptoms and other health outcomes in Gulf War veterans to veterans who did not serve in the Gulf.
This project provided a mechanism for the VA to inform veterans with amyotrophic lateral sclerosis (ALS) about clinical trials and other studies they may be eligible for.
These animal studies tested possible treatments for amyotrophic lateral sclerosis (ALS).
This pilot study collected brain function data on 50 Gulf War veterans with social and mental health complaints.
This study reviewed the brain activity of rodents given pyridostigmine bromide (PB) while under stressful conditions.
This project looked at gene expression profiles in two groups of rats.
This study was designed to better understand the cognitive health of Gulf War veterans.
This project compared learning, memory, and attention performances in groups of Gulf War returnees with and without PTSD diagnosis.
This preliminary study was designed to do a comprehensive neurological and psychological evaluations of a group of Gulf War veterans.
This animal study evaluated the effects of environmental pollutants and long-term exposure to pyridostigmine bromide on the spinal cord.
This study investigated the possible genetic link between amyotrophic lateral sclerosis (ALS) and organophosphates (insecticides) negative health effects.
This study was to investigate olfactory (sense of smell) functioning in deployed and non-deployed Gulf War veterans to determine whether there was a potential association with post-traumatic stress disorder.
This project studied pain and pain-related data among Gulf War veterans to assist in the development of a treatment.
This study evaluated Gulf War veterans with unexplained muscle, joint, and bone pain.
This study reviewed the genetic profiles of individuals identified as suffering from multisymptom illness who participated in the 1990-91 Gulf War.
This study examined combat veterans from the Vietnam and Persian Gulf Wars with and without post traumatic stress disorder.
The project's aim was to determine if unexplained illnesses in some Gulf War Veterans is similar to Chronic Fatigue Syndrome (CFS) or Multiple Chemical Sensitivity (MCS) in civilian populations.
This project tried to determine if a cause of chronic fatigue syndrome is when the body's normal reaction to stress does not work.
This project was for a multiyear study designed to evaluate the relationships between exposures (including chemical, physical, and stress) and unexplained illnesses in Gulf War veterans.
This study reviewed various data sources to determine if Gulf War veterans are at an increased risk of death due to neurologic diseases such as ALS and MS.
This project looked at new treatments for cancer.
This animal study evaluated the mouse immune system response after being infected by leishmania.
This study was designed to evaluate the relationship between post-traumatic stress disorder and physical symptoms in Gulf War veterans.
This study looked at the mental health effects of military service in Operations Desert Shield/Desert Storm.
This study compared post-war mental health symptoms between a group of Gulf War returnees to a group of troops from the same units who did not deploy.
This project was designed to learn more about mental stress and physical symptoms experienced by Gulf War veterans.
This study was designed to determine if veterans had developed neurobehavioral or mental health effects from service in the Gulf War.
This study compared a number of visual and spatial tests for people with different types of brain damage to determine which of these tests helps to identify the specific sites of damage in the brain.
This animal study looked at mouse genes to determine which ones are responsible for how the internal clock controls sleep.
This study reviewed the possible relationship between exposure to mustard gas and reproductive health problems.
This study measured several enzyme levels to determine if these chemical substances in the body were associated with either physical or mental diseases in Gulf War veterans or their spouses.
These studies conducted by the San Antonio Environmental Hazards Research Center used mouse models to identify genetic deficiencies which may increase the animals sensitivity to environmental hazards.
This project investigated how seizures disrupt brain function and memory processing.
This animal project studied the long-term effects of pyridostigmine bromide on body functions and behaviors in rats.
This program authorized the VA to provide examinations and care for any spouse or children of a Gulf War veteran who is or was suffering from an illness.
This study tested individuals from reserve units for symptoms related to post-traumatic stress disorder.
This animal study was designed to increase the understanding of how military personnel cope under the extreme stress of deployment.
This study examined brain characteristics and functions of Gulf War veterans.
This project studied chemical agents that may reduce the risk of hearing loss in some patients receiving chemotherapy treatment for brain cancer.
This animal study examined the effects of multiple vaccinations on the immune system.
This animal study was designed to determine if a biochemical substance in a mouse's body could indicate exposure to oil well fires.
This project studied what prevents the body's natural defense mechanisms against Leishmaniasis.
This animal study was designed to evaluate if the natural substance (choline) provides protection to any part of the body's nervous system.
This study reviewed the clinical behavior of human brain tumors.
The purpose of this study was to determine the effects of stress on cells in mice with a certain genetic deficiency.
This animal project studied the effects of hydrogen peroxide detoxification in protecting mice against certain environmental hazards.
The project's goal was to develop a database of U.S. service members who served in the Persian Gulf area during Operations Desert Shield/Desert Storm.
This was phase one of the VA survey study (VA-2) which included a questionnaire to review the symptoms and other health outcomes of Gulf War veterans.
This was phase two of the VA survey study (VA-2) which included telephone interviews to identify symptoms and other health outcomes of Gulf War veterans.
This was phase three of the VA survey study (VA-2) which used computer records to identify symptoms and other health outcomes of Gulf War veterans.
Joint program funded by VA and DoD to providing the Medical Follow-Up Agency with funding to perform epidemiological research on veterans.
This project looked at the next steps toward developing a human vaccine against leishmaniasis.
This animal study tested the immune sytem of mice against leishmaniasis.
The aim of this project was to continue the validation process of computer-assisted tests developed to detect when the brain is not functioning normally.
Reports & Publications
|
|
