Projects

CONTROL OF GAMMAHERPESVIRUS-ASSOCIATED MALIGNANT CATARRHAL FEVER IN RUMINANTS Appropriated (D)   Accession Number: 411144

PATHOGENESIS AND IMMUNOLOGICAL CONTROL OF SHEEP-ASSOCIATED MALIGNANT CATARRHAL FEVER IN AMERICAN BISON Specific Cooperative Agreement (S)   Accession Number: 411739

Publications

Naturally occurring sheep-associated malignant catarrhal fever in North American pigs - (Peer Reviewed Journal)

Alcaraz, A., Warren, A., Jackson, C., Gold, J., Mccoy, M., Cheong, S., Kimball, S., Sells, S., Taus, N.S., Divers, T., Li, H. 2009. Naturally occurring sheep-associated malignant catarrhal fever in North American pigs. Journal of Veterinary Diagnostic Investigation. 21(2):250-253.

Experimental infection of rabbits with ovine herpesvirus 2 from sheep nasal secretions - (Peer Reviewed Journal)

Gailbreath, K.L., Taus, N.S., Cunha, C.W., Knowles Jr, D.P., Li, H. 2008. Experimental infection of rabbits with ovine herpesvirus 2 from sheep nasal secretions. Veterinary Microbiology. 132:65-73.

Development of a Management Program for a Mixed Species Wildlife Park Following an Occurrence of Malignant Catarrhal Fever - (Peer Reviewed Journal)

Cooley, A.J., Taus, N.S., Li, H. 2008. Development of a Management Program for a Mixed Species Wildlife Park Following an Occurrence of Malignant Catarrhal Fever. Journal of Zoo and Wildlife Medicine. 39(3):380-385.

Ovine herpesvirus 2 replicates initially in the lung of experimentally infected sheep - (Peer Reviewed Journal)

Li, H., Cunha, C.W., Davies, C.J., Gailbreath, K.L., Knowles Jr, D.P., Oaks, J.L., Taus, N.S. 2008. Ovine herpesvirus 2 replicates initially in the lung of experimentally infected sheep. Journal of General Virology. 89(7):1699-1708.

Detection of ovine herpesvirus 2 major capsid gene transcripts as an indicator of virus replication in shedding sheep and clinically affected animals - (Peer Reviewed Journal)

Cunha, C.W., Traul, D., Taus, N.S., Oaks, L., O'Toole, D., Davitt, C.M., Li, H. 2008. Detection of ovine herpesvirus 2 major capsid gene transcripts as an indicator of virus replication in shedding sheep and clinically affected animals. Virus Research. 132(1-2):69-75.

IBEX-ASSOCIATED MALIGNANT CATARRHAL FEVER IN A BONGO ANTELOPE (TRAGELAPHUS EURYCEROS) - (Peer Reviewed Journal)

Okeson, D.M., Garner, M.M., Taus, N.S., Li, H., Coke, R.L. 2007. IBEX-ASSOCIATED MALIGNANT CATARRHAL FEVER IN A BONGO ANTELOPE (TRAGELAPHUS EURYCEROS). Journal of Zoo and Wildlife Medicine. 38(3): 460-464.

Intra-nasal Inoculation of American Bison (Bison bison) with Ovine Herpesvirus-2 (OvHV-2) Reliably Reproduces Malignant Catarrhal Fever - (Peer Reviewed Journal)

O'Toole, D., Taus, N.S., Montgomery, D.L., Oaks, J.L., Crawford, T.B., Li, H. 2007. Intra-nasal Inoculation of American Bison (Bison bison) with Ovine Herpesvirus-2 (OvHV-2) Reliably Reproduces Malignant Catarrhal Fever. Veterinary Pathology. 44(5):655-662

Validation of nonnested and real-time PCR for diagnosis of sheep-associated malignant catarrhal fever in clinical samples - (Peer Reviewed Journal)

Traul, D., Taus, N.S., Oaks, J.L., O'Toole, D., Rurangirwa, F.R., Baszler, T.V., Li, H. 2007. Validation of nonnested and real-time PCR for diagnosis of sheep-associated malignant catarrhal fever in clinical samples. Journal of Veterinary Diagnostic Investigation. 19:405-408

Characterization of Bison bison major histocompatibitity complex class I haplotypes - (Abstract)

Davies, C.J., Traul, D., New, D.D., Taus, N.S., O'Toole, D., Li, H. 2006. Characterization of Bison bison major histocompatibitity complex class I haplotypes. Research Workers in Animal Diseases Conference Proceedings, Chicago, Illinois. Pg. 156.

COMPARISON OF OVINE HERPESVIRUS 2 GENOMES ISOLATED FROM DOMESTIC SHEEP (OVIS ARIES) AND A CLINICALLY AFFECTED COW (BOS BOVIS) - (Peer Reviewed Journal)

Taus, N.S., Herndon, D.R., Traul, D., Stewart, J.P., Ackermann, M., Li, H., Knowles Jr, D.P., Lewis, G.S., Brayton, K.A. 2007. Comparison of ovine herpesvirus 2 genomes isolated from domestic sheep (Ovis aries) and a clinically affected cow (Bos bovis). Journal of General Virology. 88(1):40-45.

VALIDATION OF NON-NESTED AND REAL-TIME PCR FOR DIAGNOSIS OF SHEEP-ASSOCIATED MALIGNANT CATARRHAL FEVER IN CLINICAL SAMPLES - (Abstract)

Traul, D., Taus, N.S., Oaks, J.L., Otoole, D., Rurangirwa, F.R., Li, H. 2006. Validation of non-nested and real-time pcr for diagnosis of sheep-associated malignant catarrhal fever in clinical samples . Annual Meeting of the American Association of Veterinary Laboratory Diagnosticians. 131.

PREVENTION OF MALIGNANT CATARRHAL FEVER (MCF) IN A MIXED SPECIES WILD ANIMAL GAME PARK BY PRODUCTION OF VIRUS-FREE MOUFLON SHEEP - (Abstract)

Cooley, A.J., Taus, N.S., Li, H. 2006. Prevention of malignant catarrhal fever (mcf) in a mixed species wild animal game park by production of virus-free mouflon sheep. Annual Meeting of the American Association of Veterinary Laboratory Diagnosticians. 97.

OVINE HERPESVIRUS 2 MRNA EXPRESSION IN CATTLE AND BISON WITH MALIGNANT CATARRHAL FEVER - (Abstract)

Oaks, J.L., Pritchard, S., Taus, N.S., Traul, D., O'Toole, D., Li, H. 2006. Ovine herpesvirus 2 mRNA expression in cattle and bison with malignant catarrhal fever. Annual Meeting of the American Association of Veterinary Laboratory Diagnosticians. October 14-16, 2007, Minneapolis, Minnesota. pg. 88.

Pre-clinical and early clinical lesions of malignant catarrhal fever in bison following experimental inoculation with ovine nasal mucus containing ovine herpesvirus-2 (OvHV-2) - (Abstract)

O'Toole, D., Gailbreath, K.L., Oaks, J.L., Taus, N.S., Davis, W.C., Ghoddusi, M., Li, H. 2006. Pre-clinical and early clinical lesions of malignant catarrhal fever in bison following experimental inoculation with ovine nasal mucus containing ovine herpesvirus-2 (OvHV-2). American Association of Veterinary Laboratory Diagnosticians. 49th Annual Meeting of American Association of Veterinary Laboratory Diagnosticians, Minneapolis, Minn. 98.

Successful experimental induction of acute malignant catarrhal fever in bison using aerosols of ovine nasal mucus containing ovine herpesvirus 2 - (Abstract) - (15-Jul-06)

THE UPPER RESPIRATORY TRACT OF SHEEP IS THE PREDOMINANT SITE OF OVINE HERPESVIRUS-2 REPLICATION - (Abstract)

Traul, D., Taus, N.S., Oaks, J.L., Lewis, G.S., Li, H. 2006. The upper respiratory tract of sheep is the predominant site of ovine herpesvirus-2 replication. International Herpesvirus Workshop. Paper No. 8-68.

EXPERIMENTAL AEROSOL INFECTION OF CATTLE (BOS TAURUS) WITH OVINE HERPESVIRUS 2 USING NASAL SECRETIONS FROM INFECTED SHEEP - (Peer Reviewed Journal)

Taus, N.S., Oaks, J.L., Gailbreath, K.L., Traul, D., O'Toole, D., Li, H. 2006. Experimental aerosol infection of cattle (Bos taurus) with ovine herpesvirus 2 using nasal secretions from infected sheep. Veterinary Microbiology. 116(1-3):29-36.

SHEEP-ASSOCIATED MALIGNANT CATARRHAL FEVER VIRUS: PROSPECTS FOR VACCINE DEVELOPMENT - (Peer Reviewed Journal)

Li, H., Taus, N.S., Oaks, J.L. 2006. Sheep-associated malignant catarrhal fever virus: prospects for vaccine development. Expert Review of Vaccines. 5(1): 133-141.

A DEVASTATING OUTBREAK OF MALIGNANT CATARRHAL FEVER IN A BISON FEEDLOT - (Peer Reviewed Journal)

Li, H., Taus, N.S., Jones, C., Murphy, B., Evermann, J.F., Crawford, T.B. 2006. A devastating outbreak of malignant catarrhal fever in a bison feedlot. Journal of Veterinary Diagnostic Investigation. 18(1):119-123.

A NOVEL SUBGROUP OF RHADINOVIRUSES IN RUMINANTS - (Peer Reviewed Journal)

Li, H., Gailbreath, K.L., Flach, E.J., Taus, N.S., Cooley, J., Keller, J., Russell, G., Knowles Jr, D.P., Haig, D.M., Oaks, J.L., Traul, D., Crawford, T.B. 2005. A novel subgroup of rhadinoviruses in ruminants. Journal of General Virology. 86: 3021-3026.

MALIGNANT CATARRHAL FEVER: A SERIOUS DISEASE FOR AMERICAN BISON - (Abstract)

Li, H., Taus, N.S., Jones, C., Murphy, B., O'Toole, D., Evermann, J.F., Crawford, T.B. Malignant catarrhal fever: a serious disease for american bison. November, 2005, 48th Annual Meeting of American Association of Laboratory Diagnosticians, Hershey, PA. P.118

DEFINING THE MINIMUM INTRANASAL INFECTIOUS DOSE OF OVHV-2 THAT IS REQUIRED TO INDUCE INFECTION AND MALIGNANT CATARRHAL FEVER IN BISON - (Abstract)

O'Toole, D., Taus, N.S., Oaks, J.L., Li, H. Defining the minimum intranasal infectious dose of OvHV-2 that is required to induce infection and malignant catarrhal fever in bison. October, 2005, 48th Annual Meeting of American Association of Laboratory Diagnosticians, Hershey, PA. P. 114.

A NOVEL SUBGROUP OF RHADINOVIRUSES IN RUMINANTS - (Abstract)

Li, H., Gailbreath, K.L., Flach, E.J., Taus, N.S., Cooley, J., Keller, J., Russell, G., Knowles Jr, D.P., Haig, D.M., Oaks, J.L., Traul, D., Crawford, T.B. A novel subgroup of rhadinoviruses in ruminants. November, 2005, 48th Annual Meeting of American Association of Laboratory Diagnosticians, Hershey, PA. P.31.

A REAL-TIME PCR ASSAY FOR MEASURING ALCELAPHINE HERPESVIRUS-1 DNA - (Peer Reviewed Journal)

Traul, D., Elias, S., Taus, N.S., Hoesing, L.M., Oaks, L.J., Li, H. 2005. A real-time PCR assay for measuring alcelaphine herpesvirus-1 DNA. Journal of Virological Methods. 129:186-190.

TRANSMISSION OF CAPRINE HERPESVIRUS 2 IN DOMESTIC GOATS - (Peer Reviewed Journal)

Li, H., Keller, J., Knowles Jr, D.P., Taus, N.S., Oaks, J.L., Crawford, T.B. 2005. Transmission of caprine herpesvirus 2 in domestic goats. Veterinary Microbiology. 107:23-29.

EXPERIMENTAL INFECTION OF SHEEP WITH OVINE HERPESVIRUS 2 VIA AEROSOLIZATION OF NASAL SECRETIONS - (Peer Reviewed Journal)

Taus, N.S., Traul, D., Oaks, J.L., Crawford, T.B., Lewis, G.S., Li, H. 2005. Experimental infection of sheep with ovine herpesvirus 2 via aerosolization of nasal secretions. Journal of General Virology. 86:575-579.

SHEDDING OF OVINE HERPESVIRUS 2 IN SHEEP NASAL SECRETIONS: THE PREDOMINANT MODE FOR TRANSMISSION - (Peer Reviewed Journal)

Li, H., Taus, N.S., Lewis, G.S., Kim, O., Traul, D.L., Crawford, T.B. Shedding of Ovine Herpesvirus 2 in Sheep Nasal Secretions: the Predominant Mode for Transmission. Journal of Clinical Microbiology. 2004. 42(12):5558-5564.

SUCCESSFUL EXPERIMENTAL INDUCTION OF ACUTE MALIGNANT CATARRHAL FEVER IN BISON USING AEROSOLS OF OVINE NASAL MUCUS CONTAINING OVINE HERPESVIRUS 2 - (Abstract)

O'Toole, D., Taus, N.S., Davis, W.C., Crawford, T.B., Li, H. 2004. Successful experimental induction of acute malignant catarrhal fever in bison using aerosols of ovine nasal mucus containing ovine herpesvirus 2. American Association of Veterinary Laboratory Diagnosticians. 55.

DOSE DEPENDENT RESPONSES IN SHEEP EXPERIMENTALLY INFECTED WITH OVHV-2 - (Abstract)

Taus, N.S., Traul, D., Oaks, J.L., Crawford, T.B., Lewis, G.S., Li, H. 2004. Dose dependent responses in sheep experimentally infected with ovhv-2 [abstract]. Herpesvirus International Workshop. p. 11.14

SHEDDING OF OVINE HERPESVIRUS 2 IN DOMESTIC SHEEP: FREQUENCY, INTENSITY AND DURATION - (Abstract)

Li, H., Taus, N.S., Lewis, G.S., Traul, D., Kim, O., Crawford, T.B. 2004. Shedding of ovine herpesvirus 2 in domestic sheep: frequency, intensity and duration [abstract]. Herpesvirus International Workshop. p. 12.