CGAP       the Cancer Genome Anatomy Project
    CGAP HOW TO GenesChromosomesTissuesSAGEPathwaysTools  

Genes

Gene Tools

SNP Tools

Transcriptome Analysis

CGAP Data

Purchase CGAP Reagents

Related Links

Quick Links:

NCI Logo


Gene Info

Gene Information For:Hs. SHMT1, Serine hydroxymethyltransferase 1 (soluble)
Sequence ID:Y14488

Database Links

UniGeneEntrez GeneOMIMSNPViewerAssembliesSNP500Cancer

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:17p11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 18191973 - 18193004

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3687873Full LengthBC007979serine hydroxymethyltransferase 1 (soluble)
4108106Full LengthBC022874serine hydroxymethyltransferase 1 (soluble)
4523709Full LengthBC038598serine hydroxymethyltransferase 1 (soluble)

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam Motifs
NM_004169 NP_004160 P34896 EC 2.1.2.1 SHMT
NM_148918 NP_683718     SHMT

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L23928 AAA36018 P34896 EC 2.1.2.1
L23928 AAA36019 P34896 EC 2.1.2.1
L23928 AAA36020 P34896 EC 2.1.2.1
L11931 AAA63257 P34896 EC 2.1.2.1
AF017065 AAC39726    
BC007979 AAH07979 Q96HY0  
BC022874 AAH22874 P34896 EC 2.1.2.1
BC038598 AAH38598 P34896 EC 2.1.2.1
DQ893242 ABM84168    
EU176779 ABW03580    
AK223552 BAD97272 Q53ET7  
AK298415 BAG60641 B4DPM9  
AK302834 BAG64027 B4DZB5  
Y14485 CAB54838 P34896 EC 2.1.2.1
Y14486 CAB54839 P34896 EC 2.1.2.1
Y14488 CAB54841 Q9UMD0  

Homologs (from HomoloGene)

Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene		 Gene Info Protein
H.sapiens SHMT1 NP_004160 M.musculus Shmt1 20425 Gene Info NP_033197 92
R.norvegicus Shmt1 287379   XP_213324 91
A.gambiae AgaP_AGAP001065 1278659   XP_318298 67
C.elegans mel-32 175915   NP_741197 62
A.thaliana SHM2 832736   NP_568488 60
D.melanogaster CG3011 31524   NP_572278 60
N.crassa NCU02274.1 2712946   XP_331050 59
S.pombe SPAC24C9.12c 2542651   NP_594037 58
M.grisea MGG_00923 2674480   XP_368321 58
S.cerevisiae SHM2 850747   NP_013159 56

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

Kegg Pathways
Pathway information courtesy of Kegg

If you have any questions, comments, or need information about CGAP, please contact the NCI CGAP Help Desk.