Projects

TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES: THE ROLE OF GENETICS, STRAIN VARIATION, AND ENVIRONMENTAL CONTAMINATION IN DISEASE CONTROL Appropriated (D)   Accession Number: 411463

STRAIN TYPING OF CHRONIC WASTING DISEASE (CWD) AND SCRAPIE BY INTRACEREBRAL INOCULATION INTO TRANSGENIC AND INBRED MOUSE LINES Specific Cooperative Agreement (S)   Accession Number: 411895

DEVELOPMENT OF SENSITIVE IN VITRO TECHNIQUES FOR PRION DETECTION Specific Cooperative Agreement (S)   Accession Number: 409466

Publications

Validation of recto-anal mucosa associated lymphoid tissue (RAMALT) for immunohistochemical diagnosis of chronic wasting disease in white-tailed deer (Odocoileus virginianus) - (Peer Reviewed Journal) - (20-Feb-09)

Blood chimerism confounds genetic relative susceptibility testing for classical scrapie in sheep - (Peer Reviewed Journal) - (21-Jan-09)

Antemortem detection of PrP-CWD in preclinical, ranch-raised Rocky Mountain elk (Cervus elaphus nelsoni) by biopsy of the rectal mucosa - (Peer Reviewed Journal)

Spraker, T.R., Vercauteren, K.C., Gidlewski, T., Schneider, D.A., Munger, R., Balanchandran, A., Orourke, K.I. 2009. Antemortem detection of PrP-CWD in preclinical, ranch-raised Rocky Mountain elk (Cervus elaphus nelsoni) by biopsy of the rectal mucosa. Journal of Veterinary Diagnostic Investigation. 21(1):15-24.

Myenteric neurons of the ileum that express somatostatin are a target of prion neuroinvasion in an alimentary model of sheep scrapie - (Peer Reviewed Journal)

Schneider, D.A., Yan, H., Fry, L.M., Alverson, J., White, S.N., Orourke, K.I. 2008. Myenteric neurons of the ileum that express somatostatin are a target of prion neuroinvasion in an alimentary model of sheep scrapie. Acta Neuropathologica. 115(6):651-661.

A species barrier limits transmission of chronic wasting disease to mink (Mustela vison) - (Peer Reviewed Journal)

Harrington, R.D., Baszler, T.V., Orourke, K.I., Schneider, D.A., Spraker, T.R., Liggitt, H.D., Knowles Jr, D.P. 2008. A species barrier limits transmission of chronic wasting disease to mink (Mustela vison). Journal of General Virology. 89(4):1086-1096.