Projects

GENOMIC REGULATION OF SEASONAL INFERTILITY IN SWINE Appropriated (D)   Accession Number: 412437

INTEGRATION OF FUNCTIONAL GENOMICS AND QUANTATIVE GENETICS TO IMPROVE FEED EFFICIENCY IN PIGS Reimbursable (R)   Accession Number: 410305

Publications

Microarray gene expression profiles of fasting induced changes in liver and adipose tissues of pigs expressing the melanocortin-4 receptor D298N variant - (Peer Reviewed Journal) - (09-Apr-09)

Board Sponsored Invited Review: The biology and regulation of preadipocytes and adipocytes in meat animals - (Review Article) - (06-Oct-08)

Feed Intake Regulation: Interface with the reproductive axis - (Abstract) - (06-Oct-08)

Adipose tissue development in extramuscular and intramuscular depots in meat animals - (Book/Chapter) - (23-Jul-08)

Insulin-like growth factor-I (IGF-I) modulation of growth hormone (GH) and luteinizing hormone (LH) secretion in the pig - (Abstract)

Barb, C.R., Hausman, G.J. 2008. Insulin-like growth factor-I (IGF-I) modulation of growth hormone (GH) and luteinizing hormone (LH) secretion in the pig [abstract]. Joint Abstracts of the American Dairy Science and Society of Animal Science. Journal Animal Science. V 86E(Suppl.2) p. 64.

Energy Metabolism and Leptin: Effects on Neuroendocrine Regulation of Reproduction in the Gilt and Sow - (Peer Reviewed Journal)

Barb, C.R., Hausman, G.J., Lents, C.A. 2008. Energy Metabolism and Leptin: Effects on Neuroendocrine Regulation of Reproduction in the Gilt and Sow. Reproduction of Domestic Animals. V.43(Suppl.2):324-330.

Use of Transcriptional Profiling to Understand Genetic Mechanisms Responding to Fasting and MC4-R Genotypes in Pigs - (Abstract)

Lkhagvadorj, S., Qu, L., Cai, W., Couture, L., Wang, L., Anderson, L., Deckers, J., Nettleton, D., Tuggle, C., Barb, C.R., Hausman, G.J., Rekaya, R. 2008. Use of Transcriptional Profiling to Understand Genetic Mechanisms Responding to Fasting and MC4-R Genotypes in Pigs [abstract]. Midwestern Section of the American Society of Animal Science. Poster 113 p. 36.

Patterns of gene expression in pig adipose tissue: insulin-like growth factor system proteins, neuropeptide Y (NPY), NPY receptors, neurotrophic factors and other secreted factors - (Peer Reviewed Journal)

Hausman, G.J., Barb, C.R., Dean, R.G. 2008. Patterns of gene expression in pig adipose tissue: insulin-like growth factor system proteins, neuropeptide Y (NPY), NPY receptors, neurotrophic factors and other secreted factors. Domestic Animal Endocrinology. 35(1):24-34.

Sterol Regulatory Transcription Factor-1: Key Regulator of Fasting Response in the Adipose Tissue inGPigs - (Abstract)

Lkhagvadorj, S., Qu, L., Cai, W., Couture, O.P., Wang, Y., Barb, C.R., Hausman, G.J., Rekaya, R., Nettleton, D.S., Anderson, L.L., Dekkers, J.C., Tuggle, C.K. 2008. Sterol Regulatory Transcription Factor-1: Key Regulator of Fasting Response in the Adipose Tissue inGPigs [abstract]. Experimental Biology. 22:1205.6

The influence of thiazolidinediones on adipogenesis in vitro and in vivo: Potential modifiers of intramuscular adipose tissue deposition in meat animals: a review - (Peer Reviewed Journal)

Hausman, G.J., Poulos, S.P., Pringle, D.T., Azain, M.J. 2007. The influence of thiazolidinediones on adipogenesis in vitro and in vivo: Potential modifiers of intramuscular adipose tissue deposition in meat animals: a review. Journal of Animal Science. 86(E.Suppl.):E236-E243.

Patterns of gene expression in pig adipose tissue: transforming growth factors, interferons, interleukins and apolipoproteins - (Peer Reviewed Journal)

Hausman, G.J., Barb, C.R., Dean, R.G. 2007. Patterns of gene expression in pig adipose tissue: transforming growth factors, interferons, interleukins and apolipoproteins. Journal of Animal Science. p. 2445-2456.

PPARy and GLUT-4 expression as developmental regulators/markers for preadipocyte differentiation into an adipocyte - (Peer Reviewed Journal)

Fernyhough, M.E., Okine, E., Hausman, G.J., Vierck, J.L., Dodson, M.V. 2007. Ppary and glut-4 expression as developmental regulators/markers for preadipocyte differentiation into an adipocyte. Domestic Animal Endocrinology. p. 367-378.

Regulation and Role of Leptin: Pigs - (Book/Chapter)

Barb, C.R., Hausman, G.J. 2008. Regulation and Role of Leptin: Pigs. Encyclopedia of Animal Science. www.informaworld.com/10.1081/E-EAS-120043425.

FAILURE OF SHORT TERM FEED RESTRICTION TO EFFECT LUTEINIZING HORMONE OR LEPTIN SECRETION AND SUBCUTANEOUS ADIPOSE TISSUE EXPRESSION OF LEPTIN OR LEPTIN RECEPTOR IN THE PREPUBERAL GILT - (Peer Reviewed Journal)

Hart, H.A., Azain, M.J., Hausman, G.J., Reeves, D.E., Barb, C.R. 2007. Failure of short term feed restriction to effect luteinizing hormone or leptin secretion and subcutaneous adipose tissue expression of leptin or leptin receptor in the prepuberal gilt. Canadian Journal of Animal Science. 87:191-197.

The influence of thiazolidinediones on marbling in pigs: in vitro studies of muscle stromal-vascular cells from fetal and young pigs and in vivo studies of growing pigs - (Abstract)

Hausman, G.J., Poulos, S.P., Pringle, D.T., Azain, M.J. 2007. The influence of thiazolidinediones on marbling in pigs: in vitro studies of muscle stromal-vascular cells from fetal and young pigs and in vivo studies of growing pigs[abstract]. Midwestern Section of the American Society of Animal Science. p. 87.

Search for the preadipocyte progenitor proceeds to a new dimension - (Review Article)

Hausman, G.J., Hausman, D.B. 2006. Search for the preadipocyte progenitor proceeds to a new dimension. Journal of Clinical Investigation. 116(12):3103-3106.

What are subcutaneous adipocytes really good for? - (Literature)

Hausman, G.J., Hausman, D.B. 2007. What are subcutaneous adipocytes really good for?. Experimental Dermatology. 16:45-70.

A COMPARATIVE STUDY ON METHODS FOR ANALYSIS OF TWO COLOR MICROARRAY DATA CONTAINIG BIOLOGICAL AND TECHNICAL REPLICATION - (Abstract)

Zhang, W., Robbins, K., Rekaya, R., Bertrand, K., Barb, C.R., Hausman, G.J. 2006. A comparative study on methods for analysis of two color microarray data containig biological and technical replication [abstract]. World Congress of Genetics Applied in Livestock Production. p. 207.

USE OF TRANSCRIPTIONAL PROFILING TO UNDERSTAND GENETIC MECHANISMS CONTROLLING FEED INTAKE AND EFFICIENCY IN PIGS - (Abstract)

Lkhagvadorj, S., Qu, L., Cai, W., Couture, O., Wang, Y., Andrson, L., Dekkers, J., Ettleton, D., Tuggle, C., Barb, C.R., Hausman, G.J., Rekaya, R. 2006. Use of transcriptional profiling to understand genetic mechanisms controlling feed intake and efficiency in pigs [abstract]. 30th International Conference on Animal Genetics. p. C532.

THE ONTOGENY OF INSULIN-LIKE GROWTH FACTOR-I (IGF-I) MODULATION OF GH SECRETION FROM PORCINE ANTERIOR PITUITARY CELLS IN CULTURE - (Abstract)

Barb, C.R., Hausman, G.J. 2006. The ontogeny of insulin-like growth factor-I (IGF-I) modulation of GH secretion from porcine anterior pituitary cells in culture [abstract]. Joint Abstracts of the American Dairy Science and Society of Animal Science. 89(1):347. W149.

THE ROLE OF NEUROPEPTIDE Y AND INTERACTION WITH LEPTIN IN REGULATING FEED INTAKE AND LUTEINIZING HORMONE AND GROWTH HORMONE SECRETION IN THE PIG - (Peer Reviewed Journal)

Barb, C.R., Kraeling, R.R., Rampacek, G.B., Hausman, G.J. 2006. The role of neuropeptide y and interaction with leptin in regulating feed intake and luteinizing hormone and growth hormone secretion in the pig. Reproduction. 131:1127-1135.

SECRETED PROTEINS AND GENES IN FETAL AND NEONATAL PIG ADIPOSE TISSUE AND STROMAL-VASCULAR CELLS - (Peer Reviewed Journal)

Hausman, G.J., Poulos, S.P., Richardson, R.L., Barb, C.R., Andacht, T., Mynatt, R., Kirk, H., Crandall, D., Hreha, A. 2006. Secreted proteins and genes in fetal and neonatal pig adipose tissue and stromal-vascular cells. Journal of Animal Science. 84(7):1666-1681.

ADIPOGENESIS IN STROMAL-VASCULAR CELL CULTURES DERIVED FROM FETAL SEMITENDINOSUS MUSCLE AND SUBCUTANEOUS ADIPOSE TISSUE - (Peer Reviewed Journal)

Poulos, S.P., Hausman, G.J. 2006. Adipogenesis in stromal-vascular cell cultures derived from fetal semitendinosus muscle and subcutaneous adipose tissue. Adipocytes. 2:29-36.

LEPTIN IN FARM ANIMALS - (Book/Chapter)

Barb, C.R., Hausman, G.J., Ramsay, T.G. 2006. Leptin in farm animals. In: Castracane, D.V., Henson, M.C., editors. Endocrine Update. New York, NY: Springer. p.263-308.

A COMPARISON OF THIAZOLIDINEDIONE-INDUCED ADIPOGENESIS AND MYOGENESIS IN STROMAL-VASCULAR CELLS FROM SUBCUTANEOUS ADIPOSE TISSUE OR SEMITENDINOSUS MUSCLE FROM POSTNATAL PIGS - (Peer Reviewed Journal)

Poulos, S.P., Hausman, G.J. 2006. A comparison of thiazolidinedione-induced adipogenesis and myogenesis in stromal-vascular cells from subcutaneous adipose tissue or semitendinosus muscle from postnatal pigs. Journal of Animal Science. 84(5):1076-1082.

PRIMARY ADIPOCYTE CULTURE: ADIPOCYTE PURIFICATION METHODS MAY LEAD TO A NEW UNDERSTANDING OF ADIPOSE TISSUE GROWTH AND DEVELOPMENT - (Peer Reviewed Journal)

Fernyhough, M.E., Vierck, J.L., Hausman, G.J., Mir, P.S., Okine, E.K., Dodson, M.V. 2005. Primary adipocyte culture: adipocyte purification methods may lead to a new understanding of adipose tissue growth and development. Cytotechnology. 46(2-3):163-172.

Ontogeny of gene expression in the hypothalamic-pitutitary axis and luteinizing hormone secretion during pubertal development in the gilt - (Peer Reviewed Journal)

Barb, C.R., Hausman, G.J., Rekaya, R. 2006. Ontogeny of gene expression in the hypothalamic-pitutitary axis and luteinizing hormone secretion during pubertal development in the gilt. Reproduction. (Suppl)62:33-44.

GENE EXPRESSION IN THE BRAIN-PITUITARY ADIPOSE TISSUE AXIS AND LUTEINIZING HORMONE SECRETION DURING PUBERTAL DEVELOPMENT IN THE GILT - (Peer Reviewed Journal)

Barb, C.R., Hausman, G.J., Rekaya, R. Gene expression in the brain-pituitary adipose tissue axis and luteinizing hormone secretion during pubertal development in the gilt. Reproduction. 62:33-44.

TISSUE PROTEOLYTIC ENZYMES: MODIFIERS OF MUSCLE AND ADIPOSE TISSUE - (Abstract)

Hausman, G.J. 2005. Tissue proteolytic enzymes: modifiers of muscle and adipose tissue [abstract]. Journal of Animal Science Supplement. 83(1):208.

INTRAMUSCULAR ADIPOCYTES- POTENTIAL TO PREVENT LIPOTOXICITY IN SKELETAL MUSCLE - (Peer Reviewed Journal)

Poulos, S.P., Hausman, G.J. 2005. Intramuscular adipocytes- potential to prevent lipotoxicity in skeletal muscle. Adipocytes. 1(2):79-94.

FAILURE OF SHORT TERM FEED RESTRICTION TO EFFECT LEPTIN SECRETION AND SUBCUTANEOUS ADIPOSE TISSUE EXPRESSION OF LEPTIN RECEPTOR (OB-R) IN THE PREPUBERAL GILT - (Abstract)

Hart, H.A., Azain, M.J., Hausman, G.J., Reeves, D.E., Barb, C.R. 2005. Failure of short term feed restriction to effect leptin secretion and subcutaneous adipose tissue expression of leptin receptor (ob-r) in the prepuberal gilt [abstract]. Journal of Animal Science Supplement. 83(1):167.

ONTOGENY OF HYPOTHALAMIC GENE EXPRESSION DURING PREPUBERAL DEVELOPMENT IN THE GILT - (Abstract)

Barb, C.R., Richardson, R.L., Rekaya, R., Kraeling, R.R., Hausman, G.J. 2005. Ontogeny of hypothalamic gene expression during prepuberal development in the gilt [abstract]. Journal of Animal Science Supplement. 83(1):40.

ADIPOCYTES MAY NOT BE A TERMINALLY DIFFERENTIATED CELL TYPE: IMPLICATIONS FOR ANIMAL PRODUCTION - (Other)

Dodson, M.V., Fernyhough, M.E., Vierck, J.L., Hausman, G.J. 2006. Adipocytes may not be a terminally differentiated cell type: implications for animal production. Animal Science. 80(3):239-240.

A METHOD TO ESTABLISH CO-CULTURES OF MYOTUBES AND PREADIPOCYTES FROM COLLAGENASE DIGESTED NEONATAL PIG SEMITENDINOSUS MUSCLES - (Peer Reviewed Journal)

Hausman, G.J., Poulos, S.P. 2005. A method to establish co-cultures of myotubes and preadipocytes from collagenase digested neonatal pig semitendinosus muscles. Journal of Animal Science. 83:1010-1016.

DEDIFFERENTIATION OF MATURE ADIPOCYTES TO FORM ADIPOFIBROBLASTS: MORE THAN JUST A POSSIBILITY - (Peer Reviewed Journal)

Fernyhough, M.E., Helterline, D.L., Vierck, J.L., Hausman, G.J., Hill, R.A., Dodson, M.V. 2005. Dedifferentiation of mature adipocytes to form adipofibroblasts: more than just a possibility. Adipocytes 1(1):17-24.

OIL RED-0 STAINS NON-ADIPOGENIC CELLS: A PRECAUTIONARY NOTE - (Peer Reviewed Journal)

Kinkel, A.D., Fernyhough, M.E., Helterline, D.L., Vierck, J.L., Oberg, K.S., Vance, T.J., Hausman, G.J., Hill, R.A., Dodson, M.V. 2005. Oil red-0 stains non-adipogenic cells: a precautionary note. Cytotechnology 46:49-56.

LEPTIN: A METABOLIC SIGNAL AFFECTING CENTRAL REGULATION OF REPRODUCTION IN THE PIG. - (Peer Reviewed Journal)

Barb, C.R., Hausman, G.J., Czaja, K. 2005. Leptin: a metabolic signal affecting central regulation of reproduction in the pig.. Domestic Animal Endocrinology. 29:186-192.

CONJUGATED LINOLEIC ACID DURING GESTATION AND LACTATION DOES NOT ALTER SOW PERFORMANCE OR BODY WEIGHT GAIN AND ADIPOSITY IN PROGENY. - (Peer Reviewed Journal)

Poulos, S.P., Azain, M.J., Hausman, G.J. 2004. Conjugated linoleic acid during gestation and lactation does not alter sow performance or body weight gain and adiposity in progeny. Animal Research. 53. PP 275-288. 2004.

GROWTH AND DEVELOPMENT ONTOGENY: ADIPOSE TISSUE - (Book/Chapter)

Hausman, G.J., Hausman, D.B. 2004. Growth and development ontogeny: adipose tissue. In: Pond, W.G., Bell, A.W., editors. Encyclopedia of Animal Science. New York, NY: Taylor & Francis Group, LLC. p. 684-687.

SECRETED AND SIGNALING GENES AND PROTEINS IN FETAL AND NEONATAL PIG ADIPOSE TISSUE AND STROMAL-VASCULAR CELLS. - (Abstract)

Hausman, G.J., Poulos, S.P., Richardson, R.L., Barb, C.R., Andacht, T., Mynatt, R., Pecot, H., Crandall, D., Hreha, A. Secreted and signaling genes and proteins in fetal and neonatal pig adipose tissue and stromal-vascular cells.. Journal of Animal Science. 2004. v. 82. suppl. 1. p. 200.

ONTOGENY OF UTERINE GENE EXPRESSION IN THE PREPUBERAL PIG - (Abstract)

Richardson, R.L., Barb, C.R., Lee Rutherford, L., Kraeling, R.R., Hausman, G.J., Rekaya, R. Ontogeny of uterine gene expression in the prepuberal pig. Journal of Animal Science Supplement. 2004. v. 82. suppl. 1. p. 65.

ONTOGENY OF OVARIAN GENE EXPRESSION IN THE PREPUBERAL PIG - (Abstract)

Richardson, R.L., Barb, C.R., Lee Rutherford, L., Kraeling, R.R., Hausman, G.J., Rekaya, R. Ontogeny of ovarian gene expression in the prepuberal pig. Journal of Animal Science Supplement. 2004. v. 82. suppl. 1. p. 65.

RECRUITMENT AND DIFFERENTIATION OF INTRAMUSCULAR PREADIPOCYTES IN STROMAL-VASCULAR CELL CULTURES DERIVED FORM NEONATAL PIG SEMITENDINOSUS MUSCLES - (Peer Reviewed Journal)

Hausman, G.J., Poulos, S.P. 2004. Recruitment and differentiation of intramuscular preadipocytes in stromal-vascular cell cultures derived form neonatal pig semitendinosus muscles. Journal of Animal Science. 2004. v. 82. p. 429-437.

GROWTH AND DEVELOPMENT: CELL DIFFERENTIATION - (Book/Chapter)

Poulos, S.P., Hausman, G.J. 2004. Growth and development: cell differentiation. In: Pond, W.G., Bell, A.W., editors. Encyclopedia of Animal Science. New York, NY: Taylor & Francis Group, LLC. p. 505-509.

ADIPOSE TISSUE ANGIOGENESIS. - (Peer Reviewed Journal)

Hausman, G.J., Richardson, R.L. 2004. Adipose tissue angiogenesis. Journal of Animal Science. 2004. v. 82. p. 925-934.

ADIPOSE TISSUE ANGIOGENESIS. - (Abstract)

hausman, G.J. Adipose tissue angiogenesis. Journal of Animal Science. 2003. v. 81(Suppl.1): Abstract p. 7.

PREADIPOCYTE RECRUITMENT IS ENHANCED BY CIGLITAZONE OR TROGLITAZONE IN SUBCUTANEOUS ADIPOSE STROMAL-VASCULAR (S-V) CELL CULTURES BUT NOT INTRAMUSCULAR S-V CELL CULTURES. - (Abstract)

POULOS, S.P., HAUSMAN, G.J. PREADIPOCYTE RECRUITMENT IS ENHANCED BY CIGLITAZONE OR TROGLITAZONE IN SUBCUTANEOUS ADIPOSE STROMAL-VASCULAR (S-V) CELL CULTURES BUT NOT INTRAMUSCULAR S-V CELL CULTURES.. JOURNAL OF ANIMAL SCIENCE. 2003. v. 81(Suppl.1): Abstract p. 94.

DEXAMETHASONE INDUCED PREADIPOCYTE RECRUITMENT IN PORCINE STROMAL-VASCULAR (S-V) CELL CULTURES OBTAINED BEFORE AND AFTER THE ONSET OF FETAL ADIPOGENESIS. - (Peer Reviewed Journal)

Hausman, G.J. Dexamethasone induced preadipocyte recruitment and expression of CCAAT/enhancing protein alpha and peroxisome proliferator activated receptor-gamma proteins in porcine stromal-vascular (S-V) cell cultures obtanained before and after the onset of fetal adipogenesis. General and Comparative Endocrinology. 2003. v. 133. p. 61-70.

PROTEINS PRESENT IN CONDITIONED MEDIA ARE ALTERED IN DEXAMETHASONE-INUCED ADIPOGENESIS OF PRIMARY PORCINE STROMAL-VASCULAR CELL CULTURES. - (Abstract)

Poulos, S.P., Hausman, G.J. Proteins present in conditioned media are altered in dexamethasone-induced adipogenesis of primary porcine stromal-vascular cell cultures. Biomedical and Health Sciences Institute Spring symposium. 2003. p. 45.

PREADIPOCYTE RECRUITMENT IS ENHANCED BY CIGLITAZONE OR TROGLITAZONE IN SUBCUTANEOUS ADIPOSE STROMAL-VASCULAR (S-V) CELL CULTURES BUT NOT INTRAMUSCULAR S-V CELL CULTURES. - (Abstract)

POULOS, S.P., HAUSMAN, G.J. PREADIPOCYTE RECRUITMENT IS ENHANCED BY CIGLITAZONE OR TROGLITAZONE IN SUBCUTANEOUS ADIPOSE STROMAL-VASCULAR (S-V) CELL CULTURES BUT NOT INTRAMUSCULAR S-V CELL CULTURES.. BIOMEDICAL AND HEALTH SCIENCES INSTITUTE SPRING SYMPOSIUM. 2003. p. 46.

SERUM FROM NEONATAL PIGS OF DAMS FED CONJUGATED LINOLEIC ACID (CLA) ALTERS PREADIPOCYTE RECRUITMENT IN PRIMARY PORCINE STROMAL-VASCULAR CELL CULTURE - (Abstract)

Poulos, S.P., Azain, M.J., Hausman, G.J. 2002. Serum from neonatal pigs of dams fed conjugated linoleic acid (cla) alters preadipocyte recruitment in primary porcine stromal-vascular cell culture. Journal of Federation of American Societies for Experimental Biology.

EFFECTS OF INTRACEREBROVENTRICULAR LEPTIN ADMINISTRATION ON GENE GRANSCRIPTION IN ADIPOSE TISSUE - (Peer Reviewed Journal)

Qian, H., Compton, M.M., Hartzell, D.L., Hausman, G.J., Azain, M.J., Della-Fera, M.A., Baile, C.A. Effects of intracerebroventricular leptin administration on gene transcription in adipose tissue. 2002. v. 3. p. 249-259.

PRE- AND POSTNATAL DIETARY CONJUGATED LINOLEIC ACID ALTERS ADIPOSE DEVELOPMENT, BODY WEIGHT GAIN AND BODY COMPOSITION IN SPRAGUE-DAWLEY RATS - (Peer Reviewed Journal)

Poulos, S.P., Sisk, M., Hausman, D.B., Azain, M.J., Hausman, G.J. 2001. Pre- and postnatal dietary conjugated linoleic acid alters adipose development, body weight gain and body composition in sprague-dawley rats. Journal of Nutrition.