Publications

UNCOVERING GENETIC COMPONENTS INVOLVED IN EARLY REGULATORY IMMUNE RESPONSE DURING PRRSV INFECTION - (Abstract) - (05-Sep-08)

A RESPIRATORY DISEASE MODEL FOR ASSESSMENT OF CLINICAL AND PATHOLOGIC CROSS-PROTECTION FOLLOWING HETEROLOGOUS ACUTE-TYPE PRRSV CHALLENGE. - (Abstract) - (03-Sep-08)

GENETIC CONTROL OF SWINE RESPONSES TO PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS INFECTION - (Abstract) - (24-Jun-08)

GENETIC CONTROL OF SWINE RESPONSES TO PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS INFECTION - (Abstract) - (24-Jun-08)

INVESTIGATION OF IMMUNE PATHWAYS INVOLVED IN REGULATING RESPONSES TO PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME USING SWINE PROTEIN-ANNOTATED OLIGONUCLEOTIDE MICROARRAYS - (Abstract) - (28-Mar-08)

EFFECT OF PORCINE CIRCOVIRUS TYPE 2 (PCV2) VACCINATION ON PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRSV) AND PCV2 COINFECTION - (Peer Reviewed Journal)

Opriessnig T, Madson DM, Prickett JR, Kuhar D, Lunney JK, Elsener J, Halbur PG. 2008. Effect of porcine circovirus type 2 (PCV2) vaccination on porcine reproductive and respiratory syndrome virus (PRRSV) and PCV2 coinfection. Vet. Microbiol. 131: 103-14.

DIFFERENTIAL ENDOMETRIAL TRANSCRIPT EXPRESSION BETWEEN YORKSHIRE AND THE PROLIFIC MEISHAN BREED OF PIGS DURING THE CRITICAL STAGE OF CONCEPTUS ELONGATION AND EARLY ATTACHMENT - (Abstract)

Tuggle, C.K., Zhao, S.H., Wang, Y.F., Courture, O.P., Kuhar, D.J., Lunney, J.K., Ross, J.W., Lucy, M., Dekkers, J.C., Geisert, R.D. 2008. Differential endometrial transcript expression between yorkshire and the prolific meishan breed of pigs during the critical stage of conceptus elongation and early attachment. Plant and Animal Genome Conference.p 730.

BIOINFORMATIC INTEGRATION OF STRUCTURAL AND FUNCTIONAL GENOMICS DATA ACROSS SPECIES TO DEVELOP PORCINE INFLAMMATORY GENE REGULATORY PATHWAY INFORMATION - (Abstract)

Tuggle, C.K., Wang, Y.F., Couture, O.P., Qu, L., Uther, J.J., Kuhar, D.J., Lunney, J.K., Nettleton, D., Dekkers, J.C., Bearson, S.M. 2008. Bioinformatic integration of structural and functional genomics data across species to develop porcine inflammatory gene regulatory pathway information. IEEE/ACM Transactions on Computational Biology and Bioinformatics.

Computational Integration of Structural and Functional Genomics Data Across Species to Develop Information on Porcine Inflammatory Gene Regulatory Pathway - (Proceedings/Symposium)

Tuggle, C.K., Wang, Y.F., Couture, O.P., Qu, L., Uthe, J.J., Kuhar, D.J., Lunney, J.K., Nettleton, D., Dekkers, J.C., Bearson, S.M. 2008. Computational Integration of Structural and Functional Genomics Data Across Species to Develop Information on Porcine Inflammatory Gene Regulatory Pathway. In: Animal Genomics for Animal Health M.-H. Pinard, C. Gay, P.-P. Pastoret, B. Dodet (Eds); In the series Developments in Biologicals (Karger, Basel). 132:105-114.

DIFFERENTIAL ENDOMETRIAL TRANSCRIPT EXPRESSION BETWEEN YORKSHIRE AND THE PROLIFIC MEISHAN BREED OF PIGS DURING THE CRITICAL STAGE OF CONCEPTUS ELONGATION AND EARLY ATTACHMENT - (Abstract)

Tuggle, C.K., Zhao, S.H., Qu, L., Wang, Y.F., Couture, O.P., Kuhar, D.J., Lunney, J.K., Ross, J.W., Lucy, M., Dekkers, J.C., Geisert, R.D. 2007. Differential endometrial transcript expression between yorkshire and the prolific meishan breed of pigs during the critical stage of conceptus elongation and early attachment. Plant and Animal Genome Conference.p. 568.

Swine immunity and resistance to persistent Porcine Reproductive and Respiratory Syndrome virus (PRRSV) infection. - (Abstract)

Lunney, J.K., Kuhar, D.J., Prucnal, E., Molina, R., Christopher-Hennings, J., Nelson, E., Zimmerman, J., Rowland, R.R. 2007. Swine immunity and resistance to persistent Porcine Reproductive and Respiratory Syndrome virus (PRRSV) infection. Proceedings 2007 PRRS Symposium. p.49.

Computational Integration Of Structural And Functional Genomics Data Across Species To Develop Porcine Inflammatory Gene Regulatory Pathway Information - (Abstract)

Tuggle, C.K., Wang, Y.F., Couture, O.P., Qu, L., Uthe, J.J., Kuhar, D.J., Lunney, J.K., Nettleton, D., Dekkers, J.C., Bearson, S.M., Bearson,, S.D. 2007. Computational Integration Of Structural And Functional Genomics Data Across Species To Develop Porcine Inflammatory Gene Regulatory Pathway Information. Proceedings International Symposium on Animal Genomics for Animal Health,OIE, Paris, France, October 2007.p 33.

Comparative immune responses of pigs to infection with Salmonella enterica serovars of food safety (Typhimurium) and animal health (Choleraesuis) importance - (Abstract)

Lunney, J.K., Bearson, S.M., Wang, Y.F., Uthe, J.J., Qu, K., Couture, O.P., Zhao, S.H., Kuhar, D.J., Nettleton, D., Dekkers, J.C., Tuggle, C.K. 2007. Comparative immune responses of pigs to infection with Salmonella enterica serovars of food safety (Typhimurium) and animal health (Choleraesuis)importance. Proceedings 8th Intl Veterinary Immunology Symposium, Ouro Preto, Brazil. p. 49-50.

GLOBAL TRANSCRIPTIONAL RESPONSE OF PORCINE MESENTERIC LYMPH NODES TO SALMONELLA ENTERICA SEROVAR TYPHIMURIUM - (Peer Reviewed Journal)

Wang, Y.F., Qu, L., Uthe, J.J., Bearson, S.M., Kuhar, D.J., Lunney, J.K., Couture, O.P., Nettleton, D., Dekkers, J.C., Tuggle, C.K. 2007. Global transcriptional response of porcine mesenteric lymph nodes to Salmonella enterica serovar Typhimurium. Genomics. 90(1):72-84.

Swine immunity and genetic resistance to Porcine Reproductive and Respiratory Syndrome virus (PRRSV) infection. - (Abstract)

Lunney, J.K., Petry, D., Johnson, R., Kuhar, D.J., Molina, R., Christopher-Hennings, J., Zimmerman, J., Rowland R, R.R. 2007. Swine immunity and genetic resistance to Porcine Reproductive and Respiratory Syndrome virus (PRRSV) infection.

Characterizing the porcine transcriptional regulatory response to infection by Salmonella: identifying putative new NFkB direct targets through comparative bioinformatics. - (Abstract)

Tuggle, C.K., Wang, Y.F., Couture, O.P., Qu, L., Uthe, J.J., Kuhar, D.J., Lunney, J.K., Nettleton, D., Dekkers, J.C., Bearson S, M.D. 2007. Characterizing the porcine transcriptional regulatory response to infection by Salmonella: identifying putative new NFkB direct targets through comparative bioinformatics.

transcriptional response of pigs to Salmonella infection: Comparison of responses to infection with Salmonella eimerica serotype Typhimurium as that observed in S. choleraesuis infection. - (Abstract)

Lunney, J.K., Bearson S, M.D., Yang, Y.F., Uthe, J.J., Qu, L., Couture, O.P., Zhao, S.H., Kuhar, D.J., Nettleton, D., Dekkers, J.C., Tuggle, C.K. 2007. transcriptional response of pigs to Salmonella infection: Comparison of responses to infection with Salmonella eimerica serotype Typhimurium as that observed in S. choleraesuis infection.

Differential immunity in pigs with high and low responses to porcine reproductive and respiratory syndrome virus (PRRSV) infection - (Peer Reviewed Journal)

Petry, D.B., Lunney, J.K., Boyd, P., Kuhar, D.J., Blankenship, E., Johnson, R.K. 2007. Differential immunity in pigs with high and low responses to porcine reproductive and respiratory syndrome virus (PRRSV) infection. Journal of Animal Science. 85:2075-2092. http://jas.fass.org/cgi/content/full/85/9/2075.

Do immune genes influence which pigs will have persistent Porcine Reproductive and Respiratory Syndrome virus (PRRSV) infections? - (Peer Reviewed Journal)

Lunney, J.K., Rowland, R., Nelson, E., Molina, R., Hermann, J., Kuhar, D.J., Christopher-Hennings, J., Leathers, V., Zimmerman, J. 2007. Do immune genes influence which pigs will have persistent Porcine Reproductive and Respiratory Syndrome virus (PRRSV) infections?. j.Immunology 178(45):5

Do immune genes indicate which pigs will have persistent PRRSV infections? - (Abstract)

Lunney, J.K., Rowland, R., Molina, R., Hermann, J., Kuhar, D.J., Christopher, J., Nelson, E., Leathers, V.J., Zimmerman, J. 2006. Do immune genes indicate which pigs will have persistent PRRSV infections? [Abstract]. 2006 International PRRS Symposium. p. 28. Available: http://www.prrssymposium.org/ p. 40

LACK OF A STRONG NFKB-DEPENDENT TRANSCRIPTIONAL RESPONSE DURING INFECTION WITH SALMONELLA ENTERICA SEROVAR TYPHIMURIUM AS COMPARED TO THAT OBSERVED IN S. CHOLERAESUIS INFECTION - (Abstract)

Wang, Y.F., Uthe, J.J., Bearson, S.M., Kuhar, D.J., Lunney, J.K., Qu, L., Nettleton, D., Tuggle, C.K. Lack of a strong nfkb-dependent transcriptional response during infection with Salmonella enterica serovar Typhimurium as compared to that observed in Salmonella Choleraesuis infection [abstract]. International Society of Animal Genetics. p. 264.

COMPARISON OF CYTOKINE PROFILES IN PIGS SINGULARLY OR COINFECTED WITH PCV2, OR MYCOPLASMA HYOPNEUMONIAE - (Proceedings/Symposium)

Opreissnig, T., Lunney, J.K., Kuhar, D.J., Thacker, E., Halbur, P.G. 2006. Comparison of cytokine profiles in pigs singularly or coinfected with pcv2, or mycoplasma hyopneumoniae. Pig Veterinary Society International Congress Proceedings. 1:170

GENE EXPRESSION PROFILING IN SALMONELLA CHOLERAESUIS INFECTED PORCINE LUNG USING A LONG OLIGONUCLEOTIDE MICROARRAY - (Peer Reviewed Journal)

Zhao, S., Recknor, J., Kuhar, D.J., Nettleton, D., Lunney, J.K., Orley, S., Uthe, J., Bearson, S.M., Dawson, H., Tuggle, C.K. 2006. Gene expression profiling in salmonella choleraesuis infected porcine lung using a long oligonucleotide microarray. Mammalian Genome.

GENE EXPRESSION PROFILING IN SALMONELLA CHOLERAESUIS INFECTED PORCINE LUNG USING A LONG OLIGONUCLEOTIDE MICROARRAY - (Peer Reviewed Journal)

Zhao, S., Kuhar, D.J., Lunney, J.K., Dawson, H.D., Guidry, C.A., Uthe, J., Bearson, S., Recknor, J., Nettleton, D., Tuggle, C.K. 2006. Gene expression profiling in salmonella choleraesuis infected porcine lung using a long oligonucleotide microarray. Mammalian Genomics. 17:777-789.

TRANSCIPTIONAL SUPPRESSION OF SPECIFIC PORCINE IMMUNE PATHWAYS DURING INFECTION WITH SALMONELLA ENTERICA SEROTYPE TYPHIMURIUM COMPARED TO CHOLERAESUIS - (Abstract)

Wang, Y.F., Uthe, J.J., Bearson, S.M., Kuhar, D.J., Lunney, J.K., Qu, L., Couture, O., Nettleton, D., Tuggle, C.K. 2006. Transciptional suppression of specific porcine immune pathways during infection with Salmonella enterica serotype Typhimurium compared to Choleraesuis [abstract]. International Plant and Animal Genome IX Conference. p. W242.

DIFFERENTIAL IMMUNE GENE AND PROTEIN EXPRESSION IN PIGS WITH HIGH AND LOW RESPONSE TO PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRSV) - (Abstract)

Lunney, J.K., Petry, D., Boyd, P., Kuhar, D.J., Blankenship, E., Johnson, R. 2006. Differential Immune Gene And Protein Expression In Pigs With High And Low Responses To Porcine Reproductive And Respiratory Syndrome Virus (PRRSv) Infection. International Plant and Animal Genome XIV Conference. p.584. Available: http://www.intl-pag.org/14/abstracts/PAG14_P584.html

INTEGRATION OF STRUCTURAL AND FUNCTIONAL GENOMICS - (Abstract)

Zhao, S., Kuhar, D.J., Recknor, J., Lunney, J.K., Nettleton, D., Dawson, H.D., Orley, S., Uthe, J., Bearson, S.M., Tuggle, C.K. 2005. Integration of structural and functional genomies. Proceedings of Integration of Structural and Functional Genomics Sympoisium 22-25 September 2005, p. 39.

VALIDATION OF A FIRST GENERATION PORCINE LONG OLIGONUCLEOTIDE MICROARRAY FOR TRANSCRIPTIONAL PROFILING IN THE PIG. - (Peer Reviewed Journal)

Zhao, S., Recknor, J., Lunney, J.K., Nettleton, D., Kuhar, D.J., Orley, S., Tuggle, C.K. 2005. Validation of a first generation porcine long oligonucleotide microarray for transcriptional profiling in the pig. Genomics 2005, Nov. 86(5): 618-615.

UP-REGULATION OF INFLAMMATORY, REGULATORY AND TH1-IMMUNE MARKERS IN SWINE RESPONDING TO ACUTE TOXOPLASMA GONDII INFECTION. - (Abstract)

Nishi, S.M., Dawson, H.D., Kuhar, D.J., Dubey, J.P., Urban Jr, J.F., Lunney, J.K. 2005. Up-regulation of inflammatory, regulatory and th1-immune markers in swine responding to acute toxoplasma gondii infection. Proceedings of American Association of Veterinary Parasitologists. p. 33-34.

DIFFERENTIAL IMMUNITY IN PIGS WITH HIGH AND LOW RESPONSES TO PRRSV - (Proceedings/Symposium)

Lunney, J.K., Petry, D., Boyd, P., Kuhar, D.J., Blankenship, E., Johnson, R. 2005. Differential immunity in pigs with high and low responses to prrsv. In: Proceedings of the Porcine Reproductive and Respiratory Syndrome International Symposium, December 2-3, 2005, St. Louis, MO. #44. Available: http://www.prrssymposium.org/Documents/2005%20International%20PRRS%20Symposium%20-%20Proceedings.pdf

DIFFERENTIAL IMMUNITY IN PIGS WITH HIGH AND LOW RESPONSES TO PRRSV - (Abstract)

Petry, D., Lunney, J.K., Boyd, P., Kuhar, D.J., Blankenship, E., Johnson, R. 2005. Differential immunity in pigs with high and low responses to PRRSV.Proceedings Symposium on Genetics of Animal Health. p. 10.

CROSS REACTION OF ANTI-HUMAN CD MONOCLONAL ANTIBODIES ON SWINE CELLS: A SUMMARY OF THE SWINE SECTON OF THE HLDA8 ANIMAL HOMOLOGUES DATA - (Abstract)

Lunney, J.K., Aasted, B., Dominguez, J., Alvarez, B., Revilla, C., Ezquerra, A., Alonso, F., Haverson, K., Golde, W.T., Kuhar, D.J. 2004. Cross reaction of anti-human cd monoclonal antibodies on swine cells: a summary of the swine secton of the hlda8 animal homologues data. Meeting Abstract.

CROSS REACTION OF ANTI-HUMAN CD MONOCLONAL ANTIBODIES ON SWINE CELLS: A SUMMARY OF THE SWINE SECTION OF THE HLDAS ANIMAL HOMOLOGUES DATA - (Abstract)

Lunney, J.K., Dominguez, J., Alvarez, B., Revella, C., Ezquerra, A., Alonso, F., Haverson, K., Golde, W.T., Kuhar, D.J., Faldyna, M. 2004. Cross reaction of anti-human cd monoclonal antibodies on swine cells: a summary of the swine section of the hldas animal homologues data. Meeting Abstract.

IDENTIFICATION OF KEY IMUNE MEDIATORS REGULATING T HELPER 1 REPONSES SWINE - (Peer Reviewed Journal)

Dawson, H.D., Royaee, A.R., Nishi, S., Kuhar, D.J., Schnitzlein, W.M., Zuckermann, F., Urban, J., Lunney, J.K. 2004. Identification of key imune mediators regulating t helper 1 reponses swine. Veterinary Immunology and Immunopathology 100:105-111.