Award Abstract #0079243
MRI: Instrumentation Acquisition for the Development of a Wet Facility for Nano-Bioengineering
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NSF Org: |
CBET
Division of Chemical, Bioengineering, Environmental, and Transport Systems
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Initial Amendment Date: |
September 19, 2000 |
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Latest Amendment Date: |
July 16, 2001 |
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Award Number: |
0079243 |
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Award Instrument: |
Standard Grant |
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Program Manager: |
Leon Esterowitz
CBET Division of Chemical, Bioengineering, Environmental, and Transport Systems
ENG Directorate for Engineering
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Start Date: |
September 15, 2000 |
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Expires: |
August 31, 2002 (Estimated) |
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Awarded Amount to Date: |
$267276 |
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Investigator(s): |
Lisa Pruitt lpruitt@newton.berkeley.edu (Principal Investigator)
Arunava Majumdar (Co-Principal Investigator) Tony Keaveny (Co-Principal Investigator) Carolyn Bertozzi (Co-Principal Investigator) Luke Lee (Co-Principal Investigator)
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Sponsor: |
University of California-Berkeley
Sponsored Projects Office
BERKELEY, CA 94704 510/642-8109
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NSF Program(s): |
BIOMEDICAL ENGINEERING, INTEGRATIVE SYSTEMS, MAJOR RESEARCH INSTRUMENTATION
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Field Application(s): |
0203000 Health
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Program Reference Code(s): |
OTHR, 9231, 1189, 0000
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Program Element Code(s): |
5345, 1519, 1189
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ABSTRACT
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0079243
Pruitt
The objective of this NSF MRI Award is to develop a Wet Facility for Nano-Bioengineering that employs nanoengineering for the characterization of cellular to molecular-level biological systems. The facility will be unique in that it will provide laboratory equipment that enables characterization of living biological systems in their physiological environments. The research focus of the facility is based on the merger of nanotechnology and bioengineering which are both emerging fields with promise of great scientific breakthroughs in the area of tissue engineering, cell mechanics, biological processes, and imaging. The facilities will provide the resources for creating a biomimetic framework necessary for novel synthesis of engineered materials or devices. The impact of this facility will span the disciplines of mechanical engineering, electrical engineering, bioengineering, and materials science, as well as the general areas of chemistry, biology and medicine. The acquired equipment for this facility will provide the necessary tools for nanoscale characterization of cells, proteins, interfaces, and BioMEMs structures. The approach to developing this facility is to acquire several large pieces of complementary equipment that would be difficult for any single faculty member to acquire alone because of the large initial cost and associated long-term maintenance. Thus, they propose to purchase the following systems using funds from this NSF initiative: an atomic force microscope and nanoindenter with fluid chambers for cell and tissue manipulation studies, a confocal microscope for cell imaging and manipulation, an infrared spectrometer and high pressure liquid chromatography system for characterization of protein binding, and an environmental scanning electron microcope to study substructure morphology of biomaterials.
Please report errors in award information by writing to: awardsearch@nsf.gov.
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