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Award Abstract #0521239
Acquisition of a LC-MS-MS for Research in Biology, Environmental Science, and Chemistry at UT Chattanooga
| NSF Org: |
DBI
Division of Biological Infrastructure
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| Initial Amendment Date: |
August 11, 2005 |
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| Latest Amendment Date: |
August 11, 2005 |
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| Award Number: |
0521239 |
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| Award Instrument: |
Standard Grant |
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| Program Manager: |
Robyn E. Hannigan
DBI Division of Biological Infrastructure
BIO Directorate for Biological Sciences
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| Start Date: |
August 15, 2005 |
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| Expires: |
July 31, 2007 (Estimated) |
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| Awarded Amount to Date: |
$251720 |
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| Investigator(s): |
Sean Richards Sean-Richards@utc.edu (Principal Investigator)
Gregory Grant (Co-Principal Investigator)
Deborah Kreiss (Co-Principal Investigator)
Margaret Kovach (Co-Principal Investigator)
Steven Symes (Co-Principal Investigator)
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| Sponsor: |
University of Tennessee Chattanooga
615 Mccallie Avenue
Chattanooga, TN 37403 423/425-4431
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| NSF Program(s): |
MAJOR RESEARCH INSTRUMENTATION
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| Field Application(s): |
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| Program Reference Code(s): |
BIOT, 9184, 9150
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| Program Element Code(s): |
1189
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ABSTRACT
This award supports the acquisition of a Liquid Chromatography (LC) system with tandem Mass Spectrometer detection (herein referred to as LC-MS-MS). This improved LC system has columns packed with porous particles of high mechanical strength that are smaller than 2 microns. These columns have higher flow rates and increased peak capacity compared to larger particle packings, resulting in improvements in analyte resolution and sensitivity, and decreases in analysis time and solvent use. This LC/MS/MS will be used for detection and separation of non-volatile compounds including molecular polyhedra, neurotransmitters, and proteins at ultra-low concentrations (ng/L).
Many faculty, undergraduates, and graduate students from two departments will utilize this instrument for research and research training. These faculty and students represent Chemistry, Genetics, Biology, Physiology, Toxicology, and Environmental Science. In addition, at least 6 graduate students and 70 undergraduate students will use the instrument annually as part of their research and education. Students in the following three lab courses will have hands-on experience through research-oriented laboratory exercises: Instrumental Analysis, Toxicology, and Physiology. This will be the only LC/MS within a 100 mile radius of the university.
Please report errors in award information by writing to: awardsearch@nsf.gov.
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