Award Abstract #0216274
MRI: Development of a Novel Nano-mechanical Time of Flight Mass Spectrometer

NSF Org:	CBET Division of Chemical, Bioengineering, Environmental, and Transport Systems
Initial Amendment Date:	July 25, 2002
Latest Amendment Date:	July 25, 2002
Award Number:	0216274
Award Instrument:	Standard Grant
Program Manager:	Leon Esterowitz CBET Division of Chemical, Bioengineering, Environmental, and Transport Systems ENG Directorate for Engineering
Start Date:	August 1, 2002
Expires:	July 31, 2008 (Estimated)
Awarded Amount to Date:	$193971
Investigator(s):	Kamil Ekinci ekinci@bu.edu (Principal Investigator)
Sponsor:	Trustees of Boston University 881 COMMONWEALTH AVE BOSTON, MA 02215 617/353-4365
NSF Program(s):	MAJOR RESEARCH INSTRUMENTATION
Field Application(s):	0203000 Health
Program Reference Code(s):	OTHR, 5345, 1189, 0000
Program Element Code(s):	1189

ABSTRACT

0216274

Ekinci

Funding is requested for the development of a novel matrix assisted laser desorption/ionization time of flight (MALDI-TOF) mass spectrometer. The goal of this development is to replace the conventional microchannel plate (MCP) detectors in an existing MALDI-TOF mass spectrometer by resonant nano-mechanical sensors to improve its mass spectrometric capabilities.

The proposed development will result in a room temperature MALDI-TOF mass spectrometer with very high mass resolution and sensitivity and practically no upper limit for detectable mass. This is a much-needed analytical tool for chemical and biological sciences and offers prospects for studying many different macromolecules. It also appears that this will be the first application where nano-mechanical systems are being employed as ultra-fast sensors.

PUBLICATIONS PRODUCED AS A RESULT OF THIS RESEARCH

(Showing: 1 - 11 of 11).

Azak, NO; Shagam, MY; Karabacak, DM; Ekinci, KL; Kim, DH; Jang, DY.  "Nanomechanical displacement detection using fiber-optic interferometry,"  APPLIED PHYSICS LETTERS,  v.91,  2007,   

D. Karabacak, T. Kouh and K.L. Ekinci.  "Analysis of optical interferometric displacement detection in nanoelectromechanical systems,"  Journal of Applied Physics,  v.98,  2005,  p. 124309.

D. Karabacak, T. Kouh, C.C. Huang and K.L. Ekinci.  "Optical knife-edge technique for nanomechanical displacement detection,"  Applied Physics Letters,  v.88,  2006,  p. 193122.

K.L. Ekinci.  "Electromechanical Transducers at the Nanoscale: Actuation and Sensing of Motion in Nanoelectromechanical Systems (NEMS),"  Small,  v.1,  2005,  p. 786.

K.L. Ekinci and M.L. Roukes.  "Nanoelectromechanical systems,"  Review of Scientific Instruments,  v.76,  2005,  p. 061101.

K.L. Ekinci, Y.T. Yang and M.L. Roukes.  "Ultimate Limits to Inertial Mass Sensing Based upon Nanoelectromechanical Systems,"  Journal of Applied Physics,  v.95,  2004,  p. 2682.

Karabacak, DM; Yakhot, V; Ekinci, KL.  "High-frequency nanofluidics: An experimental study using nanomechanical resonators,"  PHYSICAL REVIEW LETTERS,  v.98,  2007,   

Patrick A. Truitt, Jared B. Hertzberg, C. C. Huang, Kamil L. Ekinci and Keith C. Schwab.  "Efficient and Sensitive Capacitive Readout of Nanomechanical Resonator Arrays,"  Nano Letters,  v.7,  2007,  p. 120.

T. Kouh, D. Karabacak, D.H. Kim and K.L. Ekinci.  "Diffraction effects in optical interferometric displacement detection in nanoelectromechanical systems,"  Applied Physics Letters,  v.86,  2005,  p. 013106.

T. Kouh, O. Basarir and K.L. Ekinci.  "Room-temperature operation of a nanoelectromechanical resonator embedded in a phase-locked loop,"  Applied Physics Letters,  v.87,  2005,  p. 113112.

Y.T. Yang, C. Callegari, X.L. Feng, K.L. Ekinci, and M.L. Roukes.  "Zeptogram-Scale Nanomechanical Mass Sensing,"  Nano Letters,  v.6,  2006,  p. 583.


(Showing: 1 - 11 of 11).

Please report errors in award information by writing to: awardsearch@nsf.gov.