Award Abstract #0216239
Development of a Kingdon Trap Mass Spectrometer for High Performance Chemical and Biochemical Analysis

NSF Org:	CHE Division of Chemistry
Initial Amendment Date:	August 6, 2002
Latest Amendment Date:	January 4, 2006
Award Number:	0216239
Award Instrument:	Standard Grant
Program Manager:	Carlos A. Murillo CHE Division of Chemistry MPS Directorate for Mathematical & Physical Sciences
Start Date:	August 15, 2002
Expires:	July 31, 2007 (Estimated)
Awarded Amount to Date:	$736226
Investigator(s):	R. Graham Cooks cooks@purdue.edu (Principal Investigator) Vincent Jo Davisson (Co-Principal Investigator) Scott McLuckey (Co-Principal Investigator)
Sponsor:	Purdue University Young Hall West Lafayette, IN 47907 765/494-4600
NSF Program(s):	MAJOR RESEARCH INSTRUMENTATION
Field Application(s):
Program Reference Code(s):	OTHR, 0000
Program Element Code(s):	1189

ABSTRACT

With support from the Major Research Instrumentation (MRI) Program, Prof. R. Graham Cooks of Purdue University will develop a state-of-the-art Kingdon trap mass spectrometer for high performance chemical and biochemical analysis. This instrument represents a fundamentally new approach to high accuracy/precision mass measurements. In addition, its performance should be equivalent to a Fourier Transform-Ion Cyclotron Resonance (FT-ICR) instrument, which is considerably more expensive.

The project will impact the education of a number of graduate students and postdoctoral associates at Purdue, who will work directly to develop the instrument or will be involved in its testing. A set of short courses in biological instrumentation will also be offered.

PUBLICATIONS PRODUCED AS A RESULT OF THIS RESEARCH

(Showing: 1 - 5 of 5).

G. Wu, R.J. Noll, W.R. Plass, Q. Hu, R.H. Perry, R.G. Cooks.  "Ion Trajectory Simulations of Axial AC Dipolar Excitation in the Orbitrap,"  Int. J. Mass Spectrom.,  v.254,  2006,  p. 53.

Qizhi Hu, Alexander A. Makarov, R. Graham Cooks and Robert J. Noll.  "Resonant AC Dipolar Excitation for Ion Motion Control in the Orbitrap Mass Analyzer,"  Journal of Physic Chemistry A,  v.110,  2006,  p. 2682.

Qizhi Hu, Hongyan Li, Robert J. Noll, Alexander Makarov, Mark Hardman, and R. Graham Cooks.  "The Orbitrap: A New Mass Spectrometer, JMS Feature Article,"  Journal of Mass Spectrometry,  v.40,  2005,  p. 430.

Qizhi Hu, Nari Talaty, Robert J. Noll and R. Graham Cooks.  "Desorption Electrospray Ionization (DESI) using an Orbitrap Mass Spectrometer: Exact Mass Measurements on Drugs and Peptides,"  Rapid Commun. Mass Spectrom.,  v.20,  2006,  p. 3403.

Qizhi Hu, R. Graham Cooks, Robert J. Noll.  "Phase-Enhanced Selective Ion Ejection in an Orbitrap Mass Spectrometer,"  J. Am. Soc. Mass Spectrom.,  v.18,  2007,  p. 980.


(Showing: 1 - 5 of 5).

Please report errors in award information by writing to: awardsearch@nsf.gov.