Barbara Shukitt-Hale
Human Nutrition Research Center on Aging
Research Physical Scientist
Phone: (617) 556-3118
Fax: (617) 556-3222
Room 714 USDA-ARS-HNRCA
711 WASHINGTON STREET BOSTON, MA, 02111-0000
Troen, A.M., Shea-Budgell, M., Shukitt Hale, B., Smith, D., Selhub, J., Rosenberg, I. 2008. B-vitamin deficiency causes hyperhomocysteinemia and vascular cognitive impairment in mice. Proceedings of the National Academy of Sciences. 105(34):12474-12479.
Rabin, B.M., Joseph, J.A., Shukitt Hale, B. 2008. Effects of Berry Fruits on Neurocognitive Deficits Produced by Exposure to Space Radiation. In: Arora, R. Herbal Radiomodulators Applications in Medicine, Homeland Defence and Space. Wallingford, UK: Institute of Nuclear Medicine and Allied Sciences. p.151-161.
Joseph, J.A., Smith, M.A., Perry, G., Shukitt Hale, B. 2008. Polyphenols and Polyunsaturate Fatty Acids: The Pollyanna's of Age-Related Cognitive Decline, Neurodegenerative Disease. In Coulston, A.M. and Boushey, C.J., editors. Nutrition in the Prevention and Treatment of Disease. 2nd edition. San Diego: Elsevier. p. 269-287.
Kalt, W., Joseph, J.A., Shukitt Hale, B. 2007. Blueberries and Human Health: A Review of Current Research. Journal of American Pomological Society. 61:151-160.
Rabin, B.M., Joseph, J.A., Shukitt Hale, B., Carey, A.N. 2007. Dietary modulation of the effects of exposure to 56FE particles. Advances in Space Research. 40(4):576-580.
Carrihill-Knoll, K.L., Rabin, B.M., Shukitt Hale, B., Joseph, J.A., Carey, A. 2007. Amphetamine-Induced Taste Aversion Learning in Young and Old F-344 Rats Following Exposure to 56Fe Particles. Pharmacology, Biochemistry and Behavior. 29(2):69-76.
Joseph, J.A., Shukitt Hale, B., Lau, F.C. 2007. Fruit Polyphenols and their effects on Neuronal Signaling and Behavior in Senescence. Annals of the New York Academy of Sciences. 1100:470-485.
Carey, A.N., Shukitt Hale, B., Rabin, B.M., Joseph, J.A. 2007. Interaction between age and exposure to 56Fe particles on behavior and neurochemistry. Advances in Space Research. 39:987-993.
Rabin, B.M., Carrihill-Knoll, K.L., Carey, A.N., Shukitt Hale, B., Joseph, J.A., Foster, B.C. 2007. Elevated plus-maze performance of Fischer-344 rats as a function of age and of exposure to 56Fe particles. Advances in Space Research. 39:981-986.
Shukitt Hale, B., Casadesus, G., Carey, A.N., Rabin, B.M., Joseph, J.A. 2007. Exposure to 56Fe irradiation accelerates normal brain aging and produces deficits in spatial learning and memory. Advances in Space Research. 39:1087-1092.
Lau, F.C., Shukitt Hale, B., Joseph, J.A. 2007. Nutritional Intervention in Brain Aging: Reducing the Effects of Inflammation and Oxidative Stress. Inflammation in the Pathogenesis of Chronic Diseases:The COX-2 controversy. Subcellular Biochemistry. Volume 42. New York, NY:Springer Publication. p.299-318.
Shukitt Hale, B., Carey, A.N., Jenkins, D., Rabin, B.M., Joseph, J.A. 2007. Beneficial effects of fruit extracts on neuronal function and behavior in a rodent model of accelerated aging. Neurobiology of Aging.28:1187-1194.
Lau, F.C., Shukitt Hale, B., Joseph, J.A. 2006. Beneficial effects of berryfruit polyphenols on neuronal behavioral aging. Journal of the Science of Food and Agriculture.86:2251-2255.
Crews, F.T., Nixon, K., Kim, D., Joseph, J.A., Shukitt Hale, B., Qin, L., Zou, J. 2006. Bht blocks nfkb activation and ethanol-induced brain damage. Alcoholism: Clinical and Experimental.30(11):1938-1949.
Goyarzu, P., Malin, D.H., Moon, W.D., Moy, E., Moy, D., Jennings, R., Lippold, S., Shukitt Hale, B., Joseph, J.A. 2006. A blueberry-enriched antioxidant diet reduces an age-related deficit in one trial per day discriminative reward learning. Society for Neuroscience Abstracts and Proceedings.
Lau, F.C., Shukitt Hale, B., Joseph, J.A. 2005. Age related neuronal and behavioral deficits are improved by polyphenol rich blueberry supplementation. CRC Press. p. 499.
Shukitt Hale, B., Carey, A.N., Simon, L.E., Mark, D.A., Joseph, J.A. 2006. Effects of Concord Grape Juice on Cognitive and Motor Deficits in Aging. Nutrition. 22:295-302.
Shukitt Hale, B., Carey, A.N., Kalt, W., Mcdonald, J., Vinqvist, M., Joseph, J.A. 2005. Differential effects of blueberry extract preparations on cogntive and motor function in aging: the role of phenolics. Society for Neuroscience Abstracts and Proceedings. Abstract No. 93.5.
Carrihill-Knoll, K.L., Maloney, B.K., Rabin, B.M., Shukitt Hale, B., Joseph, J.A., Carey, A.N. 2005. Effects of age and exposure to gound-based models of cosmic rays on elevated plus maze performance in rats. Society for Neuroscience Abstracts and Proceedings. Abstract No. 656.10.
De Rivera, C., Shukitt Hale, B., Joseph, J.A., Mendelson, J.R. 2006. The effects of antioxidants in the senescent auditory cortex. Neurobiology of Aging. 27(7):1035-1044.
Shukitt Hale, B., Meterko, V., Carey, A.N., Bielinski, D., Mcguie, T., Galli, R., Joseph, J.A. 2005. Dietary supplementation with fruit polyphenolics ameliorates age-related deficits in behavior and neuronal markers of inflammation and oxidative stress. Age. 2005, 27, 49-57.
Joseph, J.A., Shukitt Hale, B., Casadesus, G. 2005. Reversing the deleterious effects of aging on neuronal communication and behavior: the beneficial properties of fruit polyphenolics. American Journal of Clinical Nutrition 2005, 81 (Suppl.) 313S-316S
Rabin, B.M., Carrihill-Knoll, K.L., Carey, A.N., Shukitt Hale, B., Joseph, J.A. 2005. Effect of diet on the disruption of operant responding at different ages following exposure to fe56 particles. Age. 205, 27, 69-73.
Rabin, B.M., Shukitt Hale, B., Joseph, J.A., Tood, P. 2005. Diet as a factor in behavioral radiation protection following exposure to heavy particles. American Society for Gravitation and Space Biology 18(2)June 2005.
Andres-Lacueva, C., Shukitt Hale, B., Galli, R.L., Jaurengui, O., Lamuela-Raventos, R.M., Joseph, J.A. 2005. Anthocyanins in aged blueberry-fed rats are found centrally and may enhance memory. Nutritional Neuroscience, April 2005:8(2): 111-120.
Rabin, B.M., Joseph, J.A., Shukitt Hale, B., 2005. Effects of age and diet on the heavy particle-induced disruptions of operant responding produced by a ground-based model for exposure to cosmic rays. Brain Research 1036(2005) 122-129.
Rabin, B.M., Joseph, J.A., Shukitt Hale, B. 2005. A longitudinal study of operant responding in rats irradiated at two months of age. Radiation Research. 164:552-555.
Casadesus, G., Stellwagen, H.M., Shukitt Hale, B., Rabin, B.M., Joseph, J.A. 2005. Hippocampal neurogenesis and psa-ncam expression following exposure to 56fe particles mimics that seen during aging. Gerontology Journal. 40 249-254
Youdim, K.A., Shukitt Hale, B., Joseph, J.A. 2004. Flavonoids and the brain: interactions at the blood brain barrier and their physiological effect on the cns. Free Radical Biology and Medicine, VOL 37, NO11 PP. 1683-1693.
Joseph, J.A., Shukitt Hale, B., Casadesus, G. 2006. The beneficial effects of fruit and vegetable supplementation on neuronal signaling and behavior in aging: beyond antioxidants. In: Stagg, J.J. and Foster, J. G. Editors. Nutrients, Stress and Medical Disorders. Totowa, MJ:Humana Press. p. 67-82
Joseph, J.A., Shukitt Hale, B., Smith, M. 2004. Nutrition and communication in the aged brain: can you hear us now? Acarology International Congress Proceedings.
Joseph, J.A., Shukitt Hale, B., Casadesus, G. 2004. The beneficial properties of fruit polyphenols on neuronal communication and behavior in aging. In: Stagg, J.J., Foster, J.G. editors. Medicinal and Aromatic Plants: Production, Business and Applications. West Virginia: Mountain State University Press. p.18-30.
Joseph, J.A., Shukitt Hale, B. 2004. Fruit polyphenolics and signaling in the aged brain:altering motor and cognitive deficits. In: Ozben, T., Chevion. M., editors. Frontiers in Aging and Neurodegenerative Disorders: Fundamental Aspects, Clinical Perspectives and New Insights. Amsterdam, The Netherlands:IOS Press. p. 170-181.
Casadesus, G., Shukitt Hale, B., Cantuti-Castelvetri, I., Rabin, B.M., Joseph, J.A. 2004. The effects of heavy particle irradiation on exploration and response to environmental change. Advances in Space Research.
Rabin, B.M., Joseph, J.A., Shukitt Hale, B. 2004. Heavy particle irradiation, neurochemistry and behavior: thresholds, dose-response curves and recovery of function. Advances in Space Research. 33:1330-1333.
Shukitt Hale, B., Carey, A.N., Casadesus, G., Galli, R.L., Joseph, J.A. 2003. Mechanisms involved in blueberry enhancements of motor and cognitive function in young and old rats. Soc. Neurosci. Abs. 2003, 29. 633.14
Rabin, B.M., Jenkins, D.G., Joseph, J.A., Shukitt Hale, B. 2003. Effects of antioxidant diets on age- and heavy particle-induced disruption of operant responding in rats. Society for Neuroscience Abstracts and Proceedings.
Goyarzu, P., Lau, F.C., Kaufmann, J., Jennings, R., Taglialatela, G., Shukitt Hale, B., Joseph, J.A., Malin, D. 2003. Age-related increased in brain nf-kb is attenuated by blueberry-enriched antioxidant diet. Society for Neuroscience Abstracts and Proceedings.
Shukitt Hale, B., Carey, A.N., Joseph, J.A. Phytochemicals in foods and everages: Effects on the Central Nervous System. In lieberman, H.R., Kanarek, R.B., and Prasad, C.eds. Nutritional Neuroscience. CRC Press, Taylor & Francis Group, LLC Boca Raton, FL, 2005, 393-404.
Joseph, J.A., Arendash, G., Gordon, M., Diamond, D., Shukitt Hale, B., and Morgan, D. Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr. Neurosci. 2003, 6: 153-162.
Shukitt-Hale, B., Casadesus, G., Cantuti-Castelvetri, I., Rabin, B.M., and Joseph, J.A. Cognitive deficits induced by 56Fe radiation exposure. Adv. Space Res. 2003, 31: 119-126.
Rabin, B.M., Joseph, J.A., and Shukitt-Hale, B. Long-term changes in amphetamine-induced reinforcement and aversion in rats following exposure to 56Fe particles. Adv. Space Res. 2003, 31: 127-133.
Shukitt-Hale, B., Andres-Lacueva, C., Galli, R.L., Jauregui, O., Lamuela-Raventos, R.M., and Joseph, J.A. Polyphenolics can localize within the brains of aged rats fed a blueberry - supplemented diet. Soc. Neurosci. Abs. 2002, 28, 294.6.
Rabin, B.M., Shukitt-Hale, B., Joseph, J.A., Buhler, L.L., Jenkins, D.G., and Eggleston, A.M. Interaction between heavy particle irradiation and age in the disruption of fixed - ratio operant responding in rats. Soc. Neurosci. Abs. 2002, 28, 889.11.
Galli, R.L., Shukitt Hale, B., Bielinski, D.F., Andres-Lacueva, C., Joseph, J.A. 2002. Dietary supplementation with fruit polyphenolics ameliorates age-related deficits in behavior and neuronal markers of inflammation and oxidative stress. Society for Neuroscience Abstracts and Proceedings.
Mcguire, S.O., Shukitt Hale, B., Joseph, J.A., Sortwell, C.E., Fleming, M.F., Marchionini, D.M., Kanaan, N.M., Daley, B., Collier, T.J. 2002. Dietary supplementation with blueberry extracts improves the survival and function of grafted embryonic dopamine neurons in rats. Society for Neuroscience Abstracts and Proceedings.
Casadesus, G., Stellwagen, H., Szprengiel, A., Galli, R.L., Smith, M.A., Shukitt Hale, B., Joseph, J.A. 2002. Modulation of hippocampal neurogenesis and cognitive performance in the aged rat: the blueberry effect. Society for Neuroscience Abstracts and Proceedings.
RABIN, B.M., SHUKITT HALE, B., SZPRENGIEL, A., JOSEPH, J.A. EFFECTS OF HEAVY PARTICLES IRRADIATION AND DIET ON AMPHETAMINE- AND LITHIUM CHLORIDE-INDUCED TASTE AVOIDANCE LEARNING IN RATS. BRAIN RESEARCH.853:31-6.
CASADESUS, G., SHUKITT HALE, B., JOSEPH, J.A. PRACTICING CALORIC RESTRICTION OR EATING A DIET HIGH IN ANTIOXIDANTS: EQUIVALENT PATHS TO SUCCESSFUL AGING?. NEUROBIOLOGY OF AGING. 23(5):747-69,2002.
Rabin, B. M., Shukitt-Hale, B., Joseph, J. A., and Denisova, N. Effects of exposure to 56Fe particles on the acquisition of a conditioned place preference in rats. Physica Medica 2001, 17 (Suppl. 1): 196-197.