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Mechanisms of Particulate-Induced Allergic Asthma
EPA Grant Number: R832139C003Subproject: this is subproject number 003 , established and managed by the Center Director under grant R832139
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
Center: Johns Hopkins Center for Childhood Asthma in the Urban Environment
Center Director: Breysse, Patrick
Title: Mechanisms of Particulate-Induced Allergic Asthma
Investigators: Wills-Karp, Marsha
Institution: Johns Hopkins University
EPA Project Officer: Fields, Nigel
Project Period: November 1, 2003 through October 31, 2008
RFA: Centers for Children's Environmental Health and Disease Prevention Research (2003)
Research Category: Health Effects , Children's Health
Description:
Objective:The objectives of this research project are to: (1) establish a causal relationship between particulate matter (PM) exposure and asthma morbidity; and (2) determine the mechanisms by which PM elicits these effects.
Publications and Presentations:Publications have been submitted on this subproject: View all 11 publications for this subproject | View all 39 publications for this center
Journal Articles:Journal Articles have been submitted on this subproject: View all 11 journal articles for this subproject | View all 38 journal articles for this center
Supplemental Keywords:particulate matter, PM, airway hyperresponsiveness, AHR, asthma, complement factor 3, C3, children’s health, Baltimore,
,
HUMAN HEALTH, Air, Geographic Area, Scientific Discipline, Health, RFA, PHYSICAL ASPECTS, Health Effects, Health Risk Assessment, Physical Processes, particulate matter, Allergens/Asthma, State, Maryland (MD), allergens, children's health, air toxics, respiratory, air pollution, airborne pollutants, children, exposure, asthma triggers, asthma, human exposure, PM
Progress and Final Reports:
2004 Progress Report
2005 Progress Report
Main Center Abstract and Reports:
R832139 Johns Hopkins Center for Childhood Asthma in the Urban Environment
Subprojects under this Center:
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R832139C001 The Epidemiology of Susceptibility to Airborne Particulates and Allergens to Asthma in African Americans
R832139C002 A Randomized Controlled Trial of Behavior Changes in Home Exposure Control
R832139C003 Mechanisms of Particulate-Induced Allergic Asthma
R832139C004 Dendritic Cell Activation by Particulate Matter and Allergen