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Study Details
<< Query results list
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Information Source
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Newman, J., et al. 2006. "PCBs and Cognitive Functioning of Mohawk Adolescents." Neurotoxicology and Teratology 28:439-445. |
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| Age when Exposed* age description below |
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| Age when Assessed* age description below |
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| Chemical | Polychlorinated Biphenyls (PCBs) | |||||
| Exposure Source | Industrial / Occupational | |||||
| Exposure Medium | Not Specified | |||||
| Exposure Route | Not Specified | |||||
| Species | Human | |||||
| Study Description and Health Effects/Endpoints |
This study evaluated a possible association between polychlorinated biphenyl (PCB) exposure and cognitive abilities in adolescents. There were significant correlations between serum PCB concentrations and three subtest scores: Delayed Recall Index (p=0.019); Long Term Retrieval (p=0.004); and Comprehension-Knowledge (p=0.043). “These subtle negative effects provide a warning that more serious effects could occur from greater exposure to environmental PCBs.” |
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| Exposure Information and Comments/Notes |
A total of 271 Mohawk adolescents aged 10-16 years and their mothers were evaluated. They lived at the Akwesasne Mohawk Nation at the juncture of New York, Quebec, and Ontario. Serum samples from the adolescents were tested for 101 PCB congeners. Cognitive abilities were evaluated using three tests: Woodcock Johnson-Revised Tests of Cognitive Ability, Standard and Supplemental Batteries (includes the Long Term Retrieval and Comprehension-Knowledge subtests); The Ravens Progressive Matrices, Standard Form; and the Test of Memory and Learning (TOMAL; includes the Delayed Recall Index subtest). The mean sum PCB serum concentration was 0.731±0.366 parts per billion (ppb). The authors stated that these levels “are not considered high when compared to toxicant-specific background levels for other populations.” |
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| Editorial Comments | none |
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