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Dietary Exposures of Young Children, Part 1: Model Development and Study Design
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| Abstract: | Young children contact surfaces (hands, floors, etc.) that may be contaminated with pesticides. Thus, dietary exposures of young children are difficult to measure, but are needed to support the aggregate exposure assessments. Evaluation of dietary field protocols and a total dietary intake model was the goal of this study. Diazinon with a half life of 8 hrs was chosen as the primary pesticide in order to detect a difference in exposure as indicated by the amount of metabolite in urine samples on a daily basis. Other samples collected to determine the model parameters included a 24-hr duplicate-diet, leftover touched and untouched foods, food-surface samples, food-press sampler samples, an activity diary, video tape, hand prints and wipes, surface wipes and press, indoor/outdoor air, entrance soil, and morning urine. One to three year old children were recruited based on diazinon use in their home and a surface wipe screening of diazinon at levels greater than 5 ng/cm2. Sampling was scheduled for six consecutive days following the day of applicabion. The child performed routine activities on exposed days. Controlled activities for eating and handling foods by the child were monitored on alternate unexposed days to determine if differences in exposure were detectable using food, environmental, and morning urine samples. Video tapes were analyzed to obtain contact frequencies and durations. The various samples were successfully collected and dietary exposures calculated from the collected samples. The estimated total dietary exposure calculated from the model will determine if the model adequately predicts dietary exposures of chidlren to pesticides when incorporating their activities. |
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| Citation: | Melnyk, L. J., M. R. Berry Jr., G. G. Akland, Y. Hu, and E. D. Pellizzari. Dietary Exposures of Young Children, Part 1: Model Development and Study Design. Presented at ISEA Annual Conference, Monterey, CA, October 24-27, 2000. |
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| Contact: |
Mary P. O'Bryant - (919)-541-4871 or obriant.mary@epa.gov
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| Division: |
Microbiological & Chemical Exposure Assessment Division |
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| Branch: |
Chemical Exposure Research Branch |
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| Product Type: |
Abstrct/Oral |
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| Presented: |
10/24/2000 |
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