Aroclor 1254 Quickview (CASRN 11097-69-1)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

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Status of Data for Aroclor 1254

File First On-Line: 10/01/1994; Last Significant Revision: 10/01/1994

Category (section)	Status	Last Revised
Oral RfD Assessment	On-line	11/01/1996
Inhalation RfC Assessment	No data
Carcinogenicity Assessment	No data

Synonyms

11097-69-1
Aroclor 1254
Arochlor 1254
Chlorierte Biphenyle, Chlorgehalt 54% [German]

Clorodifenili, cloro 54% [Italian]
Diphenyle chlore, 54% de chlore [French]
HSDB 6357
NCI-C02664

Aroclor 1254 Source Documents

Aroclor 1254 Summary

Revision History

Date	Section	Description
04/01/1997	III., IV., V.	Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.

See IRIS Summary for complete revision history.

Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect	Point of Departure*	UF	MF	RfD
Ocular exudate, inflamed and prominent Meibomian glands, distorted growth of finger and toe nails; decreased antibody (IgG and IgM) response to sheep erythrocytes	LOAEL : 0.005 mg/kg-day	300	1	2 x10^-5 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

Principal and Supporting Studies (Oral RfD)
- Monkey clinical and immunologic studies, Arnold et al., 1994a,b; Tryphonas et al., 1989, 1991a,b
Confidence in the Oral RfD
- Study -- Medium
- Database -- Medium
- RfD -- Medium

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

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