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2005 Progress Report: Children’s Environmental Health Center

EPA Grant Number: R831861
Center: USC Center for Children’s Environmental Health
Center Director: Gilliland, Frank
Title: Children’s Environmental Health Center
Investigators: Gilliland, Frank , Diaz-Sanchez, David , Froines, John R. , Gong, Henry , McConnell, Rob
Institution: University of Southern California
EPA Project Officer: Fields, Nigel
Project Period: April 1, 2004 through March 31, 2009
Project Period Covered by this Report: April 1, 2005 through March 31, 2006
Project Amount: $7,181,692
RFA: Centers for Children's Environmental Health and Disease Prevention Research (2003)
Research Category: Health Effects , Children's Health

Description:

Objective:

The objectives of the Center are to:  (1) investigate the role of ambient air pollutants and genetic susceptibility in airway inflammation and in asthma occurrence during childhood; (2) investigate the mechanism for the modulating effects of ambient air pollutants on allergic inflammation in children; (3) implement a community-based participatory research program to respond to community concerns about the effects of regional ambient air pollutants and locally emitted fresh vehicle exhaust on early life asthma; and (4) provide a scientific resource for the broader community involved in protecting children’s environmental health.

Progress Summary:

To complete the Center objectives, the following projects have been initiated:

RD831861C001:  Urban Air Pollution and Persistent Early Life Asthma.

RD831861C002:  Pollution-Enhanced Allergic Inflammation and Phase II Enzymes.

RD831861C003:  Air Pollution, Exhaled Breath Markers, and Asthma in Susceptible Children.

The progress and accomplishments for these projects is reported in the individual 2005 Annual Reports for RD831861C001, RD831861C002, and RD831861C003.

Future Activities:

See the future activities included in the individual 2005 Annual Reports for RD831861C001, RD831861C002, and RD831861C003.


Journal Articles: 193 Displayed | Download in RIS Format

Other center views: All 210 publications 196 publications in selected types All 193 journal articles

Type Citation Sub Project Document Sources
Journal Article Avol EL, Navidi WC, Colome SD. Modeling ozone levels in and around Southern California homes. Environmental Science & Technology 1998;32:463-468. R831861 (2005)
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Journal Article Avol EL, Tan SM, Gauderman WJ, Vora H, London SJ, Peters JM. Follow-up of "lost" subjects in a longitudinal air pollution health study. American Journal of Respiratory and Critical Care Medicine 2000;161(3):A308. R831861 (2005)
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Journal Article Avol EL, Gauderman WJ, Tan SM, London SJ, Peters JM. Respiratory effects of relocating to areas of differing air pollution levels. American Journal of Respiratory and Critical Care Medicine 2001;164(11):2067-2072. R831861 (2004)
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Journal Article Barraza-Villarreal A, Sunyer J, Hernandez-Cadena L, Escamilla-Nunez MC, Sienra-Monge JJ, Ramirez-Aguilar M, Cortez-Lugo M, Holguin F, Diaz-Sanchez D, Olin AC, Romieu I. Air pollution, airway inflammation, and lung function in a cohort study of Mexico City schoolchildren. Environmental Health Perspectives 2008;116(6):832-838. R831861 (2005)
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Journal Article Bastain TM, Gilliland FD, Li YF, Saxon A, Diaz-Sanchez D. Intraindividual reproducibility of nasal allergic responses to diesel exhaust particles indicates a susceptible phenotype. Clinical Immunology 2003;109(2):130-136. R831861 (2004)
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  • Abstract from PubMed
  • Journal Article Berg J, McConnell R, Milam J, Galvan J, Kotlerman J, Thorne P, Jones C, Ferdman R, Eggleston P, Rand C, Lewis MA, Peters J, Richardson J. Rodent allergen in los angeles inner city homes of children with asthma. Journal of Urban Health 2008;85(1):52-61. R831861 (2005)
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    Journal Article Berhane K, Thomas DC. Discussion on "Combining evidence on air pollution and daily mortality from the 20 largest US cities: a hierarchical modeling strategy." Journal of the Royal Statistical Society Series A: Statistics in Society 2000;163(3):263-302. R831861 (2005)
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    Journal Article Berhane K, McConnell R, Gilliland F, Islam T, Gauderman WJ, Avol E, London SJ, Rappaport E, Margolis HG, Peters JM. Sex specific effects of asthma on pulmonary function in children. American Journal of Respiratory and Critical Care Medicine 2000;162(5):1723-1730. R831861 (2004)
    R831861 (2005)
    R826708 (2000)
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  • Journal Article Berhane K, Thomas DC. A two-stage model for multiple time series data of counts. Biostatistics 2002;3(1):21-32. R831861 (2004)
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    Journal Article Berhane K, Gauderman W, Stram D, Thomas D. Statistical issues in studies of the long term effects of air pollution: The Southern California Children’s Health Study. Statistical Science 2004;19(3):414-449. R831861 (2005)
  • Abstract: Project Euclid Abstract
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  • Journal Article Bernstein JA, Alexis N, Barnes C, Bernstein IL, Bernstein JA, Nel A, Peden D, Diaz-Sanchez D, Tarlo SM, Williams PB. (2004). Health effects of air pollution. Journal of Allergy and Clinical Immunology 114(5):1116-1123. R831861 (2004)
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    Journal Article Cho AK, Di Stefano E, You Y, Rodriquez CE, Schmitz DA, Kumagai Y, Miguel AH, Eiguren-Fernandez A, Kobayashi T, Avol E, Froines JR. Determination of four quinones in diesel exhaust particles, SRM 1649a and atmospheric PM2.5. Aerosol Science and Technology 2004;38(Suppl 1):68-81. R831861 (2004)
    R831861 (2005)
    R827352 (Final)
    R827352C001 (Final)
    R827352C009 (Final)
    R827352C013 (Final)
  • Abstract: Ingenta Connect Abstract
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  • Other: Childrens Centers PDF
  • Journal Article Conti DV, Cortessis V, Molitor J, Thomas DC. Bayesian modeling of complex metabolic pathways. Human Heredity 2003;56(1-3):83-93. R831861 (2005)
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    Journal Article Conti DV, Gauderman WJ. SNPs, haplotypes, and model selection in a candidate gene region: the SIMPle analysis for multilocus data. Genetic Epidemiology 2004;27(4):429-441. R831861 (2005)
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    Journal Article Corren J, Diaz-Sanchez D, Saxon A, Deniz Y, Reimann J, Sinclair D, Davancaze T, Adelman D. Effects of omalizumab, a humanized monoclonal anti-IgE antibody, on nasal reactivity to allergen and local IgE synthesis. Annals of Allergy, Asthma and Immunology 2004;93(3):243-248. R831861 (2004)
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  • Journal Article Cozen W, Avol E, Diaz-Sanchez D, McConnell R, Gauderman WJ, Cockburn MG, Zadnick J, Jyrala M, Mack TM. Use of an electrostatic dust cloth for self-administered home allergen collection. Twin Research and Human Genetics 2008;11(2):150-155. R831861 (2005)
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    Journal Article de Villiers TM, Peters JM, Gilliland FD. Methods to determine whether air pollution associated deficits in lung function growth are correlated with small airways structure and function assessed by HRCT: Results from a pilot study. Epidemiology 2005;16(5):S144. R831861 (2005)
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    Journal Article de Villiers T, Gilliland F, Li Y, Diaz-Sanchez D. Secondhand smoke, inflammatory responses and Glutathione S-Transferase M1: Results of a randomized challenge experiment. Epidemiology 2007;18(5):S39. R831861 (2005)
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    Journal Article Delfino RJ, Gong H Jr, Linn WS, Pellizzari ED, Hu Y. Asthma symptoms in Hispanic children and daily ambient exposures to toxic and criteria air pollutants. Environmental Health Perspectives 2003;111:647-56. R831861 (2005)
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    Journal Article Delfino RJ, Gong H, Linn WS, Hu Y, Pellizzari ED. Respiratory symptoms and peak expiratory flow in children with asthma in relation to volatile organic compounds in exhaled breath and ambient air. Journal of Exposure Analysis and Environmental Epidemiology 2003;13:348-63. R831861 (2005)
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    Journal Article Diaz-Sanchez D, Proietti L, Polosa R. Diesel fumes and the rising prevalence of atopy: an urban legend? Current Allergy and Asthma Reports 2003;3(2):146-152. R831861 (2004)
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  • Journal Article Diaz-Sanchez D, Riedl M. Diesel effects on human health: a question of stress? American Journal of Physiology—Lung Cellular and Molecular Physiology 2005;289(5):L722-L723. R831861 (2004)
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  • Full-text: AJP Full Text
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  • Journal Article Diaz-Sanchez D, Rumold R, Gong H Jr. Challenge with environmental tobacco smoke exacerbates allergic airway disease in human beings. Journal of Allergy and Clinical Immunology 2006;118(2):441-446. R831861 (2005)
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    Journal Article Eggleston PA, Diette G, Lipsett M, Lewis T, Tager I, McConnell R, Chrischilles E, Lanphear B, Miller R, Krishnan J. Lessons learned from the study of childhood asthma from the Centers for Children’s Environmental Health and Disease Prevention research. Environmental Health Perspectives 2005;113(10):1430-1436. R831861 (2005)
    R826710 (Final)
    R827027 (2002)
    R829389 (2003)
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    R831710 (2004)
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    R832141 (2006)
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  • Full-text: Environmental Health Perspectives Full Text
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  • Other: Environmental Health Perspectives PDF
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  • Journal Article Eiguren-Fernandez A, Miguel AH, Froines JR, Thurairatnam S, Avol EL. Seasonal and spatial variation of polycyclic aromatic hydrocarbons in vapor-phase and PM2.5 in Southern California urban and rural communities. Aerosol Science and Technology 2004;38:447-455. R831861 (2005)
    R827352 (2004)
    R827352 (Final)
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  • Full-text: Informa World Full Text
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  • Abstract: Informa World Abstract
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  • Other: Informa World PDF
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  • Journal Article Enright PL, Linn WS, Avol EL, Margolis HG, Gong H Jr, Peters JM. Quality of spirometry test performance in children and adolescents: experience in a large field study. Chest 2000;118(3):665-671. R831861 (2005)
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  • Full-text: Chest Journal Full Text
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  • Other: Chest Journal PDF
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  • Journal Article Finkelman FD, Yang M, Orekhova T, Clyne E, Bernstein J, Whitekus M, Diaz-Sanchez D, Morris SC. Diesel exhaust particles suppress in vivo IFN-γ production by inhibiting cytokine effects on NK and NKT cells. Journal of Immunology 2004;172(6):3808-3813. R831861 (2004)
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  • Full-text: Journal of Immunology Full Text
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  • Other: Journal of Immunology PDF
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  • Journal Article Gauderman WJ, McConnell R, Gilliland F, London S, Thomas D, Avol E, Vora H, Berhane K, Rappaport EB, Lurmann F, Margolis HG, Peters J. Association between air pollution and lung function growth in southern California children. American Journal of Respiratory and Critical Care Medicine 2000;162(4 Pt 1):1383-1390. R831861 (2004)
    R831861 (2005)
    R826708 (2000)
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    R826708C001 (2000)
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  • Abstract from PubMed
  • Full-text: ATS Full Text
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  • Other: ATS PDF
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  • Journal Article Gauderman WJ, Gilliland GF, Vora H, Avol E, Stram D, McConnell R, Thomas D, Lurmann F, Margolis HG, Rappaport EB, Berhane K, Peters JM. Association between air pollution and lung function growth in southern California children: results from a second cohort. American Journal of Respiratory and Critical Care Medicine 2002;166(1):76-84. R831861 (2005)
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    Journal Article Gauderman WJ, McConnell R, Berhane K, Lurmann F, Avol E, Gilliland FD, Thomas D, Peters JM. Genes, environmental exposures and childhood asthma occurrence. Epidemiology 2002;13(4):S131. R831861 (2005)
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    Journal Article Gauderman WJ. Candidate gene association analysis for a quantitative trait, using parent-offspring trios. Genetic Epidemiology 2003;25(4):327-338. R831861 (2005)
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    Journal Article Gauderman WJ, Avol E, Gilliland F, Vora H, Thomas D, Berhane K, McConnell R, Kuenzli N, Lurmann F, Rappaport E, Margolis H, Bates D, Peters J. The effect of air pollution on lung development from 10 to 18 years of age. New England Journal of Medicine 2004;351(11):1057-1067. R831861 (2004)
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    Journal Article Gauderman WJ, Avol E, Lurmann F, Kuenzli N, Gilliland F, Peters J, McConnell R. Childhood asthma and exposure to traffic and nitrogen dioxide. Epidemiology 2005;16(6):737-743. R831861 (2004)
    R831861 (2005)
    R831861C001 (2005)
    R827352 (Final)
    R827352C007 (Final)
    R827352C009 (Final)
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  • Journal Article Gauderman WJ, Conti DV. Commentary: Models for longitudinal family data. International Journal of Epidemiology 2005;34(5):1077-1079. R831861 (2005)
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    Journal Article Gauderman WJ. Air pollution and children—An unhealthy mix. New England Journal of Medicine 2006;355:78-79. R831861 (2005)
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    Journal Article Gauderman WJ, Vora H, McConnell R, Berhane K, Gilliland F, Thomas D, Lurmann F, Avol E, Kunzli N, Jerrett M, Peters J. Effect of exposure to traffic on lung development from 10 to 18 years of age: a cohort study. The Lancet 2007;369(9561):571-577. R831861 (2005)
    R827352 (Final)
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  • Full-text: Science Direct Full Text
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  • Other: Science Direct PDF
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  • Journal Article Gauderman WJ, Murcray C, Gilliland F, Conti DV. Testing association between disease and multiple SNPs in a candidate gene. Genetic Epidemiology 2007;31(5):383-395. R831861 (2005)
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    Journal Article Geyh AS, Roberts PT, Lurmann FW, Schoell BM, Avol EL. Initial field evaluation of the Harvard active ozone sampler for personal ozone monitoring. Journal of Exposure Analysis and Environmental Epidemiology 1999;9(2):143-149. R831861 (2005)
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    Journal Article Gilliland FD, McConnell R, Peters J, Gong H Jr. A theoretical basis for investigating ambient air pollution and children’s respiratory health. Environmental Health Perspectives 1999;107(Suppl 3):403-407. R831861 (2004)
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    R826708 (2000)
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  • Abstract from PubMed
  • Full-text: Environmental Health Perspectives Full Text
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  • Other: Environmental Health Perspectives PDF
  • Journal Article Gilliland FD, Linn W, Rappaport E, Avol E, Gong H, Peters J. Effect of spirometer temperature on FEV1 in a longitudinal epidemiological study. Occupational and Environmental Medicine 1999;56(10):718-720. R831861 (2005)
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  • Journal Article Gilliland FD, Berhane K, McConnell R, Gauderman WJ, Vora H, Rappaport EB, Avol E, Peters JM. Maternal smoking during pregnancy, environmental tobacco smoke exposure and childhood lung function. Thorax 2000;55(4):271-276. R831861 (2004)
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  • Journal Article Gilliland FD, Li Y-F, Peters JM. Effects of low vitamins A, E, and C intake on children's lung function. American Journal of Respiratory and Critical Care Medicine 2001;163(5):A37. R831861 (2004)
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    Journal Article Gilliland FD, Li YF, Peters JM. Effects of maternal smoking during pregnancy and environmental tobacco smoke on asthma and wheezing in children. American Journal of Respiratory and Critical Care Medicine 2001;163(2):429-436. R831861 (2005)
    R826708 (2000)
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  • Full-text: ATS Full Text
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  • Other: ATS PDF
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  • Journal Article Gilliland FD, Islam T, Berhane K, McConnell R, Li Y-F, Peters JM. Obesity and asthma incidence in school-aged children: Results from the Children's Health Study. American Journal of Respiratory and Critical Care Medicine 2001;163(5):A37. R831861 (2004)
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    Journal Article Gilliland FD, Berhane K, Rappaport EB, Thomas DC, Avol E, Gauderman WJ, London SJ, Margolis HG, McConnell R, Islam KT, Peters JM. The effects of ambient air pollution on school absenteeism due to respiratory illnesses. Epidemiology 2001;12(1):43-54. R831861 (2004)
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  • Full-text: Epidemiology Full Text
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  • Other: Epidemiology PDF
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  • Journal Article Gilliland FD, Berhane KT, Li YF, Kim DH, Margolis HG. Dietary magnesium, potassium, sodium, and children’s lung function. American Journal of Epidemiology 2002;155(2):125-131. R831861 (2005)
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  • Journal Article Gilliland FD, Li Y-F, Dubeau L, Peters JM. Effects of GSTM1, in utero maternal smoking and ETS exposure on asthma and wheezing in children. American Journal of Respiratory and Critical Care Medicine 2002;165(8):A660. R831861 (2005)
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    Journal Article Gilliland FD, Li YF, Dubeau L, Berhane K, Avol E, McConnell R, Gauderman WJ, Peters JM. Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in children. American Journal of Respiratory and Critical Care Medicine 2002;166(4):457-463. R831861 (2005)
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  • Journal Article Gilliland FD, Rappaport EB, Berhane K, Islam T, Dubeau L, Gauderman WJ, McConnell R. Effects of glutathione S-transferase P1, M1, and T1 on acute respiratory illness in school children. American Journal of Respiratory and Critical Care Medicine 2002;166(3):346-351. R831861 (2004)
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  • Journal Article Gilliland FD, Gauderman WJ, Vora H, Rappaport E, Dubeau L. Effects of glutathione-S-transferase M1, T1, and P1 on childhood lung function growth. American Journal of Respiratory and Critical Care Medicine 2002;166(5):710-716. R831861 (2005)
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    Journal Article Gilliland FD, Berhane KT, Li YF, Gauderman WJ, McConnell R, Peters J. Children's lung function and antioxidant vitamin, fruit, juice, and vegetable intake. American Journal of Epidemiology 2003;158(6):576-584. R831861 (2004)
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    Journal Article Gilliland FD, Salam MT, Li Y-F, Langholz B. Early life risk factors for asthma: Findings from the Children's Health Study. American Journal of Respiratory and Critical Care Medicine 2003;167(7):A831. R831861 (2004)
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    Journal Article Gilliland FD, Berhane K, Li YF, Rappaport EB, Peters JM. Effects of early onset asthma and in utero exposure to maternal smoking on childhood lung function. American Journal of Respiratory and Critical Care Medicine 2003;167(6):917-924. R831861 (2005)
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    Journal Article Gilliland FD, Berhane K, Islam T, Wenten M, Rappaport E, Avol E, Gauderman WJ, McConnell R, Peters JM. Environmental tobacco smoke and absenteeism related to respiratory illness in schoolchildren. American Journal of Epidemiology 2003;157(10):861-869. R831861 (2004)
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  • Journal Article Gilliland FD, Li Y-F, Tsai W, Dubeau L. GSTP1 and GSTM1 contribute to susceptibility for asthma and wheezing following in utero exposure to tobacco smoke. American Journal of Respiratory and Critical Care Medicine 2003;167(7):A942. R831861 (2004)
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    Journal Article Gilliland FD, Berhane K, Islam T, McConnell R, Gauderman WJ, Gilliland SS, Avol E, Peters JM. Obesity and the risk of newly diagnosed asthma in school-age children. American Journal of Epidemiology 2003;158(5):406-415. R831861 (2004)
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  • Full-text: Oxford Journals Full Text
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  • Other: Oxford Journals PDF
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  • Journal Article Gilliland FD, Li Y-F, Tsai W, Dubeau L, Avol E, Peters JM. TNFα-308 genotype and ozone effects on asthma and wheezing: Results from the Children's Health Study (CHS). American Journal of Respiratory and Critical Care Medicine 2003;167(7):A580. R831861 (2004)
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    Journal Article Gilliland FD, Millstein J, Li Y-F, Lurmann F, Margolis H. Effects of prenatal exposure to O3, PM10, NO2, and CO on birth weight in full-term pregnancies. Epidemiology 2004;15(4):S34. R831861 (2004)
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    Journal Article Gilliland FD, Li Y-F, Saxon A, Diaz-Sanchez D. Glutathione-S-Transferase M1 and P1 genotypes protect against xenobiotic enhancement of allergic responses. Lancet 2004;363:119-125. R831861 (2004)
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  • Journal Article Gilliland FD, Islam T, Berhane K, McConnell R, Peters J. Smoking and asthma incidence in school-aged children: Results from the Children's Health Study. American Journal of Respiratory and Critical Care Medicine 2004;169(7):A709. R831861 (2004)
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    Journal Article Gilliland FD, Linn WS, Rappaport EB, Avol EL, McConnell RS. Exhaled nitric oxide in a population-based sample of school-aged children. Proceedings of the American Thoracic Society 2006;3:A46. R831861 (2005)
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    Journal Article Gilliland FD, Li YF, Gong H Jr, Diaz-Sanchez D. Glutathione S-Transferases M1 and P1 prevent aggravation of allergic responses by secondhand smoke. American Journal of Respiratory and Critical Care Medicine 2006;174(12):1335-1341. R831861 (2005)
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    Journal Article Gilliland FD, Islam T, Berhane K, Gauderman WJ, McConnell R, Avol E, Peters JM. Regular smoking and asthma incidence in adolescents. American Journal of Respiratory and Critical Care Medicine 2006;174(10):1094-1100. R831861 (2005)
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    Journal Article Gilliland F, Avol E, Kinney P, Jerrett M, Dvonch T, Lurmann F, Buckley T, Breysse P, Keeler G, de Villiers T, McConnell R. Air pollution exposure assessment for epidemiologic studies of pregnant women and children: lessons learned from the Centers for Children’s Environmental Health and Disease Prevention Research. Environmental Health Perspectives 2005;113(10):1447-1454. R831861 (2004)
    R831861 (2005)
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    R826710 (Final)
    R827027 (2002)
    R831845 (2005)
    R832141 (2006)
  • Abstract from PubMed
  • Full-text: Environmental Health Perspectives Full Text
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  • Other: Environmental Health Perspectives PDF
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  • Journal Article Gong H. Urban air pollution and health inequities: a workshop report. Environmental Health Perspectives 2001;109(Suppl 3):357-374. R831861 (2005)
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  • Full-text: Environmental Health Perspectives Full Text
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  • Other: Environmental Health Perspectives PDF
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  • Journal Article Gong H Jr, Linn WS, Sioutas C, Terrell SL, Clark KW, Anderson KR, Terrell LL. Controlled exposures of healthy and asthmatic volunteers to concentrated ambient fine particles in Los Angeles. Inhalation Toxicology 2003;15(4):305-325. R831861 (2005)
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  • Journal Article Gong H Jr, Linn WS, Terrell SL, Anderson KR, Clark KW, Sioutas C, Cascio WE, Alexis N, Devlin RB. Exposures of elderly volunteers with and without chronic obstructive pulmonary disease (COPD) to concentrated ambient fine particulate pollution. Inhalation Toxicology 2004;16(11-12):731-744. R831861 (2005)
    R827352 (2004)
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  • Journal Article Gong H Jr, Linn WS, Clark KW, Anderson KR, Geller MD, Sioutas C. Respiratory responses to exposures with fine particulates and nitrogen dioxide in the elderly with and without COPD. Inhalation Toxicology 2005;17(3):123-132. R831861 (2005)
    R827352 (Final)
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  • Journal Article Gong Jr H, Linn WS, Terrell SL, Anderson KR, Clark KW. Anti-inflammatory and lung function effects of montelukast in asthmatic volunteers exposed to sulfur dioxide. Chest 2001;119:402-408. R831861 (2005)
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  • Journal Article Hall JV, Brajer V, Lurmann F. Economic valuation of ozone-related school absences in the South Coast Air Basin of California. Contemporary Economic Policy 2003;21:407-417. R831861 (2004)
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    Journal Article Hricko A. 2004. Problems along the new silk road. Environmental Health Perspectives 112(15): A879. R831861 (2004)
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    Journal Article Hricko A. 2006. Ships, trucks, and trains: effects of goods movement on environmental health. (Invited guest editorial). Environmental Health Perspectives 114(4):A204-A205. R831861 (2004)
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    Journal Article Islam T, Gauderman JW, Berhane K, McConnell R, Avol E, Peters J, Gilliland FD. Low lung function predicts new onset asthma among children. Proceedings of the American Thoracic Society 2006;3:A153. R831861 (2005)
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    Journal Article Islam T, Gauderman WJ, Berhane K, McConnell R, Avol E, Peters JM, Gilliland FD. Relationship between air pollution, lung function and asthma in adolescents. Thorax 2007;62(11):957-963. R831861 (2005)
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    Journal Article Islam T, McConnell R, Gauderman WJ, Avol E, Peters JM, Gilliland FD. Ozone, oxidant defense genes, and risk of asthma during adolescence. American Journal of Respiratory and Critical Care Medicine 2008;177(4):388-395. R831861 (2005)
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    Journal Article Jerrett M, Arain A, Kanaroglou P, Beckerman B, Potoglou D, Sahsuvaroglu T, Morrison J, Giovis C. A review and evaluation of intraurban air pollution exposure models. Journal of Exposure Analysis and Environmental Epidemiology 2005;15:185-204. R831861 (2005)
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    Journal Article Jerrett M, Buzzelli M, Burnett RT, DeLuca PF. Particulate air pollution, social confounders, and mortality in small areas of an industrial city. Social Science & Medicine 2005;60:2845-63. R831861 (2005)
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    Journal Article Jerrett M, Burnett RT, Ma R, Pope CA 3rd, Krewski D, Newbold KB, Thurston G, Shi Y, Finkelstein N, Calle EE, Thun MJ. Spatial analysis of air pollution and mortality in Los Angeles. Epidemiology 2005;16(6):727-736. R831861 (2005)
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    Journal Article Jerrett M, Finkelstein M. The geography of risk in cohort studies linking air pollution exposure to mortality. Journal of Toxicology and Environmental Health 2005;68:1-36. R831861 (2005)
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    Journal Article Jerrett M, Shankardass K, Gauderman J, Berhane K, Kunzli N, Lurmann F, Avol E, Peters J, Gilliland F, Molitor J, Molitor J, McConnell R. Air pollution and asthma incidence in children. Proceedings of the American Thoracic Society 2006;3:A23. R831861 (2005)
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    Journal Article Künzli N, Avol E, Gauderman J, Rappaport E, McConnell R, Peters J, Gilliland F. GSTM1 status modifies the effects of wildfire smoke on asthma symptoms. Proceedings of the American Thoracic Society 2006;3:A502. R831861 (2005)
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    Journal Article Künzli N, Avol E, Wu J, Gauderman WJ, Rappaport E, Millstein J, Bennion J, McConnell R, Gilliland FD, Berhane K, Lurmann F, Winer A, Peters JM. Health effects of the 2003 southern California wildfire on children. American Journal of Respiratory and Critical Care Medicine 2006;174(11):1221-1228. R831861 (2005)
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    Journal Article Kanaroglou P, Jerrett M, Morrison J, Beckerman B, Arain A, Gilbert N, Brook J. Establishing an air pollution monitoring network for intra-urban population exposure assessment: a location-allocation approach. Atmospheric Environment 2005;39:2399-2409. R831861 (2005)
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    Journal Article Kraft P, Yen YC, Stram DO, Morrison J, Gauderman WJ. Exploiting gene-environment interaction to detect genetic associations. Human Heredity 2007;63(2):111-119. R831861 (2005)
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    Journal Article Kuenzli N, Jerrett M, Beckerman B, Mack W, Gilliland F, Thomas D, Peters J. Association of subclinical atherosclerosis (CAROTH) intima media thickness with residential ambient PM2.5 in healthy adults. Epidemiology 2004;15(4):S23-S24. R831861 (2005)
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    Journal Article Kuenzli N, Jerrett M, Mack WJ, Beckerman B, LaBree L, Gilliland F, Thomas D, Peters J, Hodis HN. Ambient air pollution and atherosclerosis in Los Angeles. Environmental Health Perspectives 2005;113(2):201-206. R831861 (2004)
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    Journal Article Kuenzli N, Millstein J, Avol E, Gauderman J, McConnell R, Gilliland F, Peters J. Effects of the 2003 California wildfires on children's respiratory health. European Respiratory Journal 2005;26(49):A2475. R831861 (2004)
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    Journal Article Kuenzli, N. and C. Schindler (2005). A call for reporting the relevant exposure term in air pollution case-crossover studies. J Environ Community Health 59(6):527-530. R831861 (2004)
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    Journal Article Kunzli N. The public health relevance of air pollution abatement. European Respiratory Journal 2002;20(1):198-209. R831861 (2005)
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    Journal Article Kunzli N, McConnell R, Bates D, Bastain TM, Hricko A, Lurmann F, Avol E, Gilliland FD, Peters JM. Breathless in Los Angeles: The exhausting search for clean air. American Journal of Public Health 2003;93(9):1494-1499. R831861 (2004)
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  • Journal Article Kunzli N, Vora H, Gilliland F, Gauderman JW, Lurmann F, Avol E, Thomas D, Peters J. PM2.5 fractions from non-combustion origin are not associated wtih pulmonary growth in children. American Journal of Respiratory and Critical Care Medicine 2004;169(7):A19. R831861 (2004)
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    Journal Article Kunzli N, Perez L, Lurmann F, Hricko A, Penfold B, McConnell R. An attributable risk model for exposures assumed to cause both chronic disease and its exacerbations. Epidemiology 2008;19(2):179-185. R831861 (2005)
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    Journal Article Lee YL, Gilliland FD, Wang JY, Lee YC, Guo YL. Associations of FcepsilonRIbeta E237G polymorphism with wheezing in Taiwanese schoolchildren. Clinical & Experimental Allergy 2008;38(3):413-420. R831861 (2005)
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    Journal Article Li YF, Gilliland FD, Berhane K, McConnell R, Gauderman WJ, Rappaport EB, Peters JM. Effects of in utero and environmental tobacco smoke exposure on lung function in boys and girls with and without asthma. American Journal of Respiratory and Critical Care Medicine 2000;162(6):2097-2104. R831861 (2005)
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  • Journal Article Li YF, Tsao YH, Gauderman WJ, Conti DV, Avol E, Dubeau L, Gilliland FD. Intercellular adhesion molecule-1 and childhood asthma. Human Genetics 2005;117(5):476-484. R831861 (2004)
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  • Journal Article Li YF, Gauderman WJ, Conti DV, Lin PC, Avol E, Gilliland FD. Glutathione s-transferase p1, maternal smoking, and asthma in children: a haplotype-based analysis. Environmental Health Perspectives 2008;116(3):409-415. R831861 (2005)
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    Journal Article Li Y-F, Gilliland FD, Berhane K, McConnell R, Gauderman WJ, Peters JM. Effects of in utero exposure on lung function in children with early onset asthma. American Journal of Respiratory and Critical Care Medicine 2001;163(5):A263. R831861 (2005)
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    Journal Article Li Y-F, Langholz B, Gilliland FD. Smoking cessation during pregnancy reduces risk for asthma from in utero exposure to maternal smoking. American Journal of Respiratory and Critical Care Medicine 2003;167(7):A854. R831861 (2005)
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    Journal Article Li Y-F, Tsao Y-H, Wenten MR, Dubeau L, Gilliland FD. Intercellular adhesion molecule 1 haplotypes and childhood asthma risk. American Journal of Respiratory and Critical Care Medicine 2004;169(7):A583. R831861 (2004)
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    Journal Article Li Y-F, Langholz B, Salam MT, Gilliland FD. Maternal and grandmaternal smoking patterns are associated with early childhood asthma. Chest 2005;127:1232-1241. R831861 (2004)
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  • Journal Article Li Y-F, Gauderman WJ, Avol E, Dubeau L, Gilliland FD. Associations of tumor necrosis factor G-308A with childhood asthma and wheezing. American Journal of Respiratory and Critical Care Medicine 2006;173(9):970-976. R831861 (2004)
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  • Journal Article Linn WS, Solomon JC, Gong H Jr, Avol EL, Peters JM. Temperature standardization of multiple spirometers. Journal of Occupational & Environmental Medicine 1998;40(2):148-152. R831861 (2005)
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    Journal Article Linn WS, Gong H. Respiratory health risk from particulate air pollution: current evidence and research needs. Inspiration--Singapore Thoracic Society Newsletter 2001;7(1):2-5. R831861 (2005)
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    Journal Article Linn WS, Avila M, Gong H Jr. Exhaled nitric oxide: sources of error in offline measurement. Archives of Environmental Health 2004;59(8):385-391. R831861 (2005)
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  • Journal Article Linn WS, Anderson KR, Avila M, Gong H, Rappaport EB, Avol EL, Gilliland FD. A survey of exhaled nitric oxide (eNO) in southern California schoolchildren: methodology and data quality. Proceedings of the American Thoracic Society 2006;3:A45. R831861 (2005)
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    Journal Article London SJ, James Gauderman W, Avol E, Rappaport EB, Peters JM. Family history and the risk of early-onset persistent, early-onset transient, and late-onset asthma. Epidemiology 2001;12(5):577-583. R831861 (2005)
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    Journal Article Lu R, Wu J, Turco RP, Winer AM, Atkinson R, Arey J, Paulson SE, Lurmann FW, Miguel AH, Eiguren-Fernandez A. Naphthalene distributions and human exposure in Southern California. Atmospheric Environment 2005;39:489-507. R831861 (2004)
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  • Journal Article Lurmann F, Funk T, Hyslop N, Roberts P, Hammond SK, McConnell R, Avol E. Measurement and modeling of personal exposure to ambient air pollution related to motor vehicle emissions. Epidemiology 2002;13(4):S131. R831861 (2005)
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    Journal Article Mack WJ, Kuenzli N, Jerrett M, Beckerman B, LaBree L, Gilliland F, Thomas D, Peters J, Hodis HN. Ambient air pollution and subclinical atherosclerosis. Circulation 2004;110(17):55-56. R831861 (2005)
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    Journal Article McConnell R, Berhane K, Gilliland F, London SJ, Vora H, Avol E, Gauderman WJ, Margolis HG, Lurmann F, Thomas DC, Peters JM. Air pollution and bronchitic symptoms in Southern California children with asthma. Environmental Health Perspectives 1999;107(9):757-760. R831861 (2004)
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  • Journal Article McConnell R, Berhane K, Gilliland FD, Islam T, London SJ, Gauderman WJ, Avol E, Margolis HG, Peters JM. Sports and asthma in children exposed to ozone. American Journal of Respiratory and Critical Care Medicine 2001;163(5):A174. R831861 (2005)
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    Journal Article McConnell R, Berhane K, Gilliland FD, Molitor J, Avol E, Gauderman WJ, Peters JM. Air pollution and bronchitic symptoms in children: Between community and within-community effects. Epidemiology 2002;13(4):S148. R831861 (2005)
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    Journal Article McConnell R, Berhane K, Gilliland F, London SJ, Islam T, Gauderman WJ, Avol E, Margolis HG, Peters JM. Asthma in exercising children exposed to ozone: A cohort study. Lancet 2002;359(9304):386-391. R831861 (2004)
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  • Journal Article McConnell R, Jones C, Avol E, Cozen W, Milam J, Cahero J, Richardson J. Cockroach allergen intervention: some considerations for intervention and exposure assessment. Epidemiology 2002;13(4):S135. R831861 (2004)
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    Journal Article McConnell R, Berhane K, Gilliland F, Islam T, Gauderman WJ, London SJ, Avol E, Rappaport EB, Margolis HG, Peters JM. Indoor risk factors for asthma in a prospective study of adolescents. Epidemiology 2002;13(3):288-295. R831861 (2005)
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    Journal Article McConnell R, Berhane K, Lurmann F, Molitor J, Gauderman WJ, Avol E, Rappaport E, Gilliland FD, Peters JM. Traffic and asthma prevalence in children. American Journal of Respiratory and Critical Care Medicine 2002;165(8):A492. R831861 (2004)
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    Journal Article McConnell R, Avol E, Lin V, Lurmann F. Chronic exposure to ambient ozone varies with traffic near residence. American Journal of Respiratory and Critical Care Medicine 2003;167(7):A36. R831861 (2005)
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    Journal Article McConnell R, Jones C, Milam J, Gonzalez P, Berhane K, Clement L, Richardson J, Hanley-Lopez J, Kwong K, Maalouf N, Galvan J, Platts-Mills T. Cockroach counts and house dust allergen concentrations after professional cockroach control and cleaning. Annals of Allergy, Asthma & Immunology 2003;91(6):546-552. R831861 (2004)
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  • Journal Article McConnell R, Berhane K, Molitor J, Gilliland FD. Effect modification by pet ownership. American Journal of Respiratory and Critical Care Medicine 2003;167(7):A36. R831861 (2005)
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    Journal Article McConnell R, Berhane K, Gilliland FD, Molitor J, Thomas D, Lurmann F, Avol E, Gauderman WJ, Peters JM. Prospective study of air pollution and bronchitic symptoms in children with asthma. American Journal of Respiratory and Critical Care Medicine 2003;168(7):790-797. R831861 (2004)
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  • Journal Article McConnell R, Milam J, Richardson J, Galvan J, Jones C, Thorne PS, Berhane K. Educational intervention to control cockroach allergen exposure in the homes of hispanic children in Los Angeles: results of the La Casa study. Clinical & Experimental Allergy 2005;35(4):426-433. R831861 (2004)
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  • Journal Article McConnell R, Berhane K, Molitor J, Gilliland F, Künzli N, Thorne P, Thomas D, Gauderman J, Avol E, Lurmann F, Rappaport E, Jerrett M, Peters JM. Dog ownership enhances symptomatic responses to air pollution in children with asthma. Environmental Health Perspectives 2006;114(12):1910-1915. R831861 (2005)
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  • Journal Article McConnell R, Berhane K, Yao L, Lurmann FW, Avol E, Peters JM. Predicting residential ozone deficits from nearby traffic. Science of the Total Environment 2006;363(1-3):166-174. R831861 (2004)
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  • Journal Article McConnell R, Berhane K, Yao L, Jerrett M, Lurmann F, Gilliland F, Kunzli N, Gauderman J, Avol E, Thomas D, Peters J. Traffic, susceptibility, and childhood asthma. Environmental Health Perspectives 2006;114(5):766-772. R831861 (2004)
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  • Journal Article McConnell R. Childhood incident asthma and traffic-related air pollution in a longitudinal cohort study. Epidemiology 2007;18(5):S187. R831861 (2005)
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    Journal Article McConnell R, Islam T, Berhane K, Lurmann F, Yao L, Jerrett M, Gauderman J, Gilliland F, Avol E, Thomas D, Peters J. Childhood incident asthma and traffic-related pollution in a longitudinal cohort study. Proceedings of the American Thoracic Society 2007;175:A304. R831861 (2005)
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    Journal Article Milam J, McConnell R, Yao L, Berhane K, Jerrett M, Richardson J. Parental stress and childhood wheeze in a prospective cohort study. Journal of Asthma 2008;45(4):319-323. R831861 (2005)
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    Journal Article Millstein J, Gilliland F, Berhane K, Gauderman WJ, McConnell R, Avol E, Rappaport EB, Peters JM. Effects of ambient air pollutants on asthma medication use and wheezing among fourth-grade school children from 12 Southern California communities enrolled in The Children's Health Study. Archives of Environmental Health 2004;59(10):505-514. R831861 (2005)
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    Journal Article Millstein J, Siegmund K, Conti DV, Gauderman WJ. Identifying susceptibility genes by using joint tests of association and linkage and accounting for epistasis. BMC Genetics 2005;6(Suppl 1):S147. R831861 (2004)
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    Journal Article Millstein J, Siegmund KD, Conti DV, Gauderman WJ. Testing association and linkage using affected-sib-parent study designs. Genetic Epidemiology 2005;29(3):225-233. R831861 (2004)
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    Journal Article Millstein J, Conti DV, Gilliland FD, Gauderman WJ. A testing framework for identifying susceptibility genes in the presence of epistasis. American Journal of Human Genetics 2006;78(1):15-27. R831861 (2004)
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    Journal Article Mirabelli M, Künzli N, Avol E, Gilliland F, Gauderman J, McConnell R, Rappaport E, Peters J. Increased susceptibility to wildfire smoke among children with small airways. Proceedings of the American Thoracic Society 2007;175:A829. R831861 (2005)
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    Journal Article Molitor J, Molitor N-T, Jerrett M, McConnell R, Gauderman WJ, Berhane K, Thomas D. Bayesian modeling of air pollution health effects with missing exposure data. American Journal of Epidemiology 2006;164(1):69-76. R831861 (2005)
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    Journal Article Molitor J, Jerrett M, Chang CC, Molitor NT, Gauderman J, Berhane K, McConnell R, Lurmann F, Wu J, Winer A, Thomas D. Assessing uncertainty in spatial exposure models for air pollution health effects assessment. Environmental Health Perspectives 2007;115(8):1147-1153. R831861 (2005)
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    Journal Article Mueller-Anneling L, Avol E, Peters JM, Thorne PS. Ambient endotoxin concentrations in PM10 from Southern California. Environmental Health Perspectives 2004;112(5):583-588. R831861 (2005)
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    Journal Article Navidi W. Bidirectional case-crossover designs for exposures with time trends. Biometrics 1998;54:596-605. R831861 (2005)
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    Journal Article Peters JM, Avol E, Navidi W, London SJ, Gauderman WJ, Lurmann F, Linn WS, Margolis H, Rappaport E, Gong H, Thomas DC. A study of twelve Southern California communities with differing levels and types of air pollution. I. Prevalence of respiratory morbidity. American Journal of Respiratory and Critical Care Medicine 1999;159(3):760-767. R831861 (2004)
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  • Journal Article Peters JM, Avol E, Gauderman WJ, Linn WS, Navidi W, London SJ, Margolis H, Rappaport E, Vora H, Gong H Jr, Thomas DC. A study of twelve Southern California communities with differing levels and types of air pollution. II. Effects on pulmonary function. American Journal of Respiratory and Critical Care Medicine 1999;159(3):768-775. R831861 (2004)
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  • Journal Article Peters JM, McConnell R, Berhane K, Millstein J, Lurmann F, Gauderman J, Avol E, Gilliland FD, Thomas D. Air pollution and the incidence, prevalence and severity of childhood asthma: Results from the southern California Children's Health Study. Epidemiology 2002;13(4):S132. R831861 (2004)
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    Journal Article Rappaport EB, Gilliland FD, Linn WS, Gauderman WJ. Impact of respiratory illness on expiratory flow rates in normal, asthmatic, and allergic children. Pediatric Pulmonology 2002;34(2):112-121. R831861 (2005)
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    Journal Article Richardson JL, Milam JE, Galvan J, Jones C, McConnell R. Knowledge of skin test results among parents of asthmatic children. Journal of Asthma 2005;41(2):199-204. R831861 (2004)
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  • Journal Article Riedl MA, Landaw EM, Saxon A, Diaz-Sanchez D. Initial high-dose nasal allergen exposure prevents allergic sensitization to a neoantigen. Journal of Immunology 2005;174(11):7440-7445. R831861 (2004)
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  • Journal Article Riedl MA, Nel AE. Importance of oxidative stress in the pathogenesis and treatment of asthma. Current Opinion in Allergy and Clinical Immunology 2008;8(1):49-56. R831861 (2005)
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    Journal Article Riedl MA. The effect of air pollution on asthma and allergy. Current Allergy and Asthma Reports 2008;8(2):139-146. R831861 (2005)
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    Journal Article Riedl M, Diaz-Sanchez D. Biology of diesel exhaust effects on respiratory function. Journal of Allergy and Clinical Immunology 2005;115(2):221-228. R831861 (2004)
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  • Journal Article Ritz SA, Wan J, Diaz-Sanchez D. Sulforaphane-stimulated phase II enzyme induction inhibits cytokine production by airway epithelial cells stimulated with diesel extract. American Journal of Physiology Lung Cellular and Molecular Physiology 2007;292(1):L33-L39. R831861 (2005)
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    Journal Article Romieu I, Barraza-Villarreal A, Escamilla-Nunez C, Almstrand AC, Diaz-Sanchez D, Sly PD, Olin AC. Exhaled breath malondialdehyde as a marker of effect of exposure to air pollution in children with asthma. Journal of Allergy and Clinical Immunology 2008;121(4):903-909 e906. R831861 (2005)
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    Journal Article Rondeau V, Berhane K, Thomas DC. A three-level model for binary time-series data: the effects of air pollution on school absences in the Southern California Children's Health Study. Statistics in Medicine 2005;24(7):1103-1115. R831861 (2005)
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    Journal Article Ross Z, English PB, Scalf R, Gunier R, Smorodinsky S, Wall S, Jerrett M. Nitrogen dioxide prediction in Southern California using land use regression modeling: potential for environmental health analyses. Journal of Exposure Science and Environmental Epidemiology 2006;16(2):106-114. R831861 (2005)
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    Journal Article Rumold R, Jyrala M, Diaz-Sanchez D. Secondhand smoke induces allergic sensitization in mice. The Journal of Immunology 2001;167(8):4765-4770. R831861 (2005)
    R826708 (2000)
    R826708 (2001)
    R826708 (2002)
    R826708 (Final)
    R826708C002 (2001)
  • Abstract from PubMed
  • Full-text: Journal of Immunology Full Text
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  • Other: Journal of Immunology PDF
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  • Journal Article Sahsuvaroglu T, Jerrett M. Sources of uncertainty in estimating mortality and morbidity attributable to air pollution. Journal of Toxicology and Environmental Health 2007;70(3-4):243-260. R831861 (2005)
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    Journal Article Salam MT, Gilliland F, Li Y-F, Langholz B. Early life environmental risk factors for asthma: Findings from the Children’s Health Study. Environmental Health Perspectives 2004;112(6):760-765. R831861 (2004)
    R831861 (2005)
    R831861C001 (2005)
    R826708 (2000)
    R826708 (2001)
    R826708 (2002)
    R826708 (Final)
  • Abstract from PubMed
  • Full-text: Environmental Health Perspectives Full Text
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  • Journal Article Salam MT, Langholz BM, Gilliland FD. Maternal fish consumption during pregnancy and risk of childhood asthma. American Journal of Respiratory and Critical Care Medicine 2004;169(7):A722. R831861 (2005)
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    Journal Article Salam MT, Millstein J, Li YF, Lurmann FW, Margolis HG, Gilliland FD. Birth outcomes and prenatal exposure to ozone, carbon monoxide, and particulate matter: results from the Children's Health Study. Environment Health Perspectives 2005;113(11):1638-1644. R831861 (2004)
    R831861 (2005)
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    Journal Article Salam MT, Langholz B, Li Y-F, Gilliland FD. Maternal fish consumption during pregnancy and risk of childhood asthma. Journal of Asthma 2005;42(6):513-518. R831861 (2004)
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    R826708 (Final)
  • Abstract from PubMed
  • Journal Article Salam MT, Wenten M, Gilliland FD. Endogenous and exogenous sex steroid hormones and asthma and wheeze in young women. Journal of Allergy and Clinical Immunology 2006;117(5):1001-1007. R831861 (2004)
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    Journal Article Salam MT, Lin PC, Gauderman WJ, Gilliland F. Genetic polymorphisms in microsomal epoxide hydrolase and childhood asthma. Proceedings of the American Thoracic Society 2006;3:A349. R831861 (2005)
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    Journal Article Salam MT, Margolis HG, McConnell R, McGregor JA, Avol EL, Gilliland FD. Mode of delivery is associated with asthma and allergy occurrences in children. Annals of Epidemiology 2006;16(5):341-346. R831861 (2004)
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    Journal Article Salam MT, Gilliland FD. Dietary fat and antioxidant vitamins and respiratory symptoms in children. Proceedings of the American Thoracic Society 2007;175:A272. R831861 (2005)
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    Journal Article Salam MT, Lin PC, Avol EL, Gauderman WJ, Gilliland FD. Microsomal epoxide hydrolase, glutathione S-transferase P1, traffic and childhood asthma. Thorax 2007;62(12):1050-1057. R831861 (2005)
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    Journal Article Salam MT, Gauderman WJ, McConnell R, Lin PC, Gilliland FD. Transforming growth factor- 1 C-509T polymorphism, oxidant stress, and early-onset childhood asthma. American Journal of Respiratory and Critical Care Medicine 2007;176(12):1192-1199. R831861 (2005)
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    Journal Article Salam MT, Gauderman WJ, McConnell R, Lin PC, Wenten M, Gilliland FD. Transforming growth factor-b1, traffic and childhood asthma. Proceedings of the American Thoracic Society 2007;175:A259. R831861 (2005)
    not available
    Journal Article Salam MT, Islam T, Gilliland FD. Recent evidence for adverse effects of residential proximity to traffic sources on asthma. Current Opinion in Pulmonary Medicine 2008;14(1):3-8. R831861 (2005)
    not available
    Journal Article Sawant AA, Cocker DR 3rd, Miller JW, Taliaferro T, Diaz-Sanchez D, Linn WS, Clark KW, Gong H Jr. Generation and characterization of diesel exhaust in a facility for controlled human exposures. Journal of the Air & Waste Management Association 2008;58(6):829-837. R831861 (2005)
    not available
    Journal Article Saxon A, Diaz-Sanchez D. Air pollution and allergy: you are what you breathe. Nature Immunology 2005;6(3):223-226. R831861 (2004)
    R831861 (2005)
    R826708 (2000)
    R826708 (2001)
    R826708 (2002)
    R826708 (Final)
  • Abstract: NATURE Abstract
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  • Journal Article Schlesinger RB, Kuenzli N, Hidy GM, Gotschi T, Jerrett M. The health relevance of ambient particulate matter characteristics: coherence of toxicological and epidemiological inferences. Inhalation Toxicology 2006;18(2):95-125. R831861 (2005)
    R831845 (2005)
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    Journal Article Shankardass K, McConnell RS, Milam J, Tatalovich Z, Wilson JP, Jerrett M. The association between community socioeconomic factors and prevalent asthma in southern California school children. Proceedings of the American Thoracic Society 2006;3:A153. R831861 (2005)
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    Journal Article Shankardass K, McConnell RS, Milam J, Berhane K, Tatalovich Z, Wilson JP, Jerrett M. The association between contextual socioeconomic factors and prevalent asthma in a cohort of Southern California school children. Social Science & Medicine 2007;65(8):1792-1806. R831861 (2005)
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    Journal Article Stram DO. Designs for studies of personal exposure to air pollution and the impact of measurement error. Journal of Toxicology and Environmental Health, Part A 2005;68(13-14):1181-1187. R831861 (2005)
    not available
    Journal Article Stram DO. Software for tag single nucleotide polymorphism selection. Human Genomics 2005;2(2):144-151. R831861 (2005)
    not available
    Journal Article Thomas DC. Some contributions of statistics to environmental epidemiology. Journal of The American Statistical Association 2000;95:315-319. R831861 (2005)
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    Journal Article Thomas DC, Xie R, Gebregziabher M. Two-stage sampling designs for gene association studies. Genetic Epidemiology 2004;27:401-414. R831861 (2005)
    not available
    Journal Article Thomas DC, Haile RW, Duggan D. Recent developments in genomewide association scans: a workshop summary and review. American Journal of Human Genetics 2005;77(3):337-345. R831861 (2005)
    not available
    Journal Article Thomas DC. The need for a systematic approach to complex pathways in molecular epidemiology. Cancer Epidemiology Biomarkers & Prevention 2005;14(3):557-559. R831861 (2005)
    not available
    Journal Article Thomas DC, Jerrett M, Kuenzli N, Louis TA, Dominici F, Zeger S, Schwarz J, Burnett RT, Krewski D, Bates D. Bayesian model averaging in time-series studies of air pollution and mortality. Journal of Toxicology and Environmental Health 2007;70(3-4):311-315. R831861 (2005)
    R832417C001 (2007)
  • Abstract from PubMed
  • Journal Article Thomas DC, Witte JS, Greenland S. Dissecting effects of complex mixtures: who's afraid of informative priors? Epidemiology 2007;18(2):186-190. R831861 (2005)
    not available
    Journal Article Thomas D. Why do estimates of the acute and chronic effects of air pollution on mortality differ? Journal of Toxicology and Environmental Health, Part A 2005;68(13-14):1167-1174. R831861 (2005)
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    Journal Article Thorne PS, Avol E, Anelling L, Grossman S, Peters JM. Measurement of ambient endotoxin in Southern California. American Journal of Respiratory and Critical Care Medicine 2001;163(5):A844. R831861 (2005)
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    Journal Article Thorne PS, Metwali N, Avol E, McConnell R. Evaluation of surface sampling for endotoxin using electrostatic wiping cloths. American Journal of Respiratory and Critical Care Medicine 2003;167(7):A500. R831861 (2004)
    R831861 (2005)
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    Journal Article Thorne PS, Metwali N, Avol E, McConnell RS. Surface sampling for endotoxin assessment using electrostatic wiping cloths. Annals of Occupational Hygiene 2005;49(5):401-406. R831861 (2004)
    R831861 (2005)
    R826708 (2000)
    R826708 (2001)
    R826708 (2002)
    R826708 (Final)
  • Abstract from PubMed
  • Full-text: Oxford Journals Full Text
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  • Journal Article Wan J, Diaz-Sanchez D. Phase II enzymes induction blocks the enhanced IgE production in B cells by diesel exhaust particles. Journal of Immunology 2006;177(5):3477-3483. R831861 (2005)
    R826708 (2000)
    R826708 (2001)
    R826708 (2002)
    R826708 (Final)
  • Abstract from PubMed
  • Full-text: The Journal of Immunology Full Text
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  • Journal Article Wan J, Diaz-Sanchez D. Antioxidant enzyme induction: a new protective approach against the adverse effects of diesel exhaust particles. Inhalation Toxicology 2007;19(Suppl 1):177-182. R831861 (2005)
    not available
    Journal Article Wang C, Salam MT, Islam T, Wenten M, Gauderman WJ, Gilliland FD. Effects of in utero and childhood tobacco smoke exposure and beta2-adrenergic receptor genotype on childhood asthma and wheezing. Pediatrics 2008;122(1):e107-114. R831861 (2005)
    not available
    Journal Article Wenten MR, Zaichik R, Gilliland FD. Oral contraceptive use, asthma, and wheezing in young women: results from the Children's Health Study. American Journal of Respiratory and Critical Care Medicine 2004;169(7):A528. R831861 (2005)
    not available
    Journal Article Wenten M, Berhane K, Rappaport EB, Avol E, Tsai WW, Gauderman WJ, McConnell R, Dubeau L, Gilliland FD. TNF-308 modifies the effect of second-hand smoke on respiratory illness-related school absences. American Journal of Respiratory and Critical Care Medicine 2005;172:1563-1568. R831861 (2004)
    R831861 (2005)
    R826708 (2000)
    R826708 (2001)
    R826708 (2002)
    R826708 (Final)
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  • Full-text: ATS Full Text
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  • Journal Article Westerdahl D, Fruin SA, Fine PL, Sioutas C. The Los Angeles International Airport as a source of ultrafine particles and other pollutants to nearby communities. Atmospheric Environment 2008;42(13):3143-3155. R831861 (2005)
    R832413 (2007)
    R832413 (2008)
    R832413C001 (2007)
  • Full-text: Science Direct Full Text
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  • Abstract: Science Direct Abstract
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  • Journal Article Whitekus MJ, Li N, Zhang M, Wang M, Horwitz MA, Nelson SK, Horwitz LD, Brechun N, Diaz-Sanchez D, Nel AE. Thiol antioxidants inhibit the adjuvant effects of aerosolized diesel exhaust particles in a murine model for ovalbumin sensitization. The Journal of Immunology 2002;168(5):2560-2567. R831861 (2004)
    R831861 (2005)
    R826708 (2000)
    R826708 (2001)
    R826708 (2002)
    R826708 (Final)
    R826708C001 (Final)
    R826708C002 (Final)
    R827352 (Final)
    R827352C002 (Final)
  • Abstract from PubMed
  • Full-text: Journal of Immunology Full Text
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  • Journal Article Wu J, Lurmann F, Winer A, Lu R, Turco R, Funk TH. Development of an individual exposure model for application to the Southern California Children’s Health Study. Atmospheric Environment 2005;39(2):259-273. R831861 (2004)
    R831861 (2005)
    R827352 (Final)
    R827352C015 (Final)
    R828172 (Final)
    R831845 (2005)
  • Full-text: Science Direct Full Text
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  • Abstract: Science Direct Abstract
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  • Journal Article Wu J, Funk T, Lurmann F, Winer A. Improving spatial accuracy of roadway networks and geocoded addresses. Transactions in GIS 2005;9(4):585-601. R831861 (2005)
    R827352 (Final)
    R827352C015 (Final)
    R831845 (2005)
  • Abstract: Blackwell-Synergy Abstract
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  • Journal Article Xie B, Gilliland FD, Li YF, Rockett HR. Effects of ethnicity, family income, and education on dietary intake among adolescents. Preventive Medicine 2003;36(1):30-40. R831861 (2004)
    R831861 (2005)
    R826708 (2000)
    R826708 (2001)
    R826708 (2002)
    R826708 (Final)
  • Abstract from PubMed
  • Journal Article Zeger SL, Thomas D, Dominici F, Samet JM, Schwartz J, Dockery D, Cohen A. Exposure measurement error in time-series studies of air pollution: concepts and consequences. Environmental Health Perspectives 2000;108(5):419-426. R831861 (2005)
    not available
    Journal Article Diaz-Sanchez, D., R. Rumold, and H. Gong. 2002. Controlled second-hand smoke exposure enhances ragweed-induced IgE, Th2 cytokines and histamine production in allergic subjects. Journal of Allergy and Clinical Immunology 109(1):S90. R831861 (2004)
    R831861 (2005)
    not available
    Supplemental Keywords:

    asthma, children, susceptibility, community, children’s health, health effects, risk assessment, airway disease, allergen, asthma, childhood respiratory disease, children’s environmental health, community-based intervention, outreach and education, respiratory problems, , HUMAN HEALTH, ENVIRONMENTAL MANAGEMENT, Air, Scientific Discipline, Health, RFA, Health Effects, Risk Assessment, Health Risk Assessment, Children's Health, Biochemistry, Environmental Chemistry, mobile sources, automotive exhaust, engine exhaust, allergen, respiratory problems, children's environmental health, childhood respiratory disease, susceptibility, outreach and education, community-based intervention, airway disease, automotive emissions, ambient particle pollution, asthma, Human Health Risk Assessment
    Relevant Websites:

    http://www.usc.edu/schools/medicine/research/centers_programs/cehc/exit EPA
    http://www.usc.edu/schools/medicine/departments/preventive_medicine/divisions/occupational/occ_environmental/cehc/index.htmlexit EPA

    Progress and Final Reports:
    2004 Progress Report
    Original Abstract

    Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
    R831861C001 Urban Air Pollution and Persistent Early Life Asthma
    R831861C002 Pollution-Enhanced Allergic Inflammation and Phase II Enzymes
    R831861C003 Air Pollution, Exhaled Breath Markers, and Asthma in Susceptible Children

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    The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.


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