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University of Washington Center for Child Environmental Health Risks Research

Grant Number R831709


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  • Book (5)
  • Book Chapter (18)
  • Journal Article (168)
  • Report (6)
  • Reference Type Reference Title Journal Author Citation Progress Report Year Document Sources
    Book Paraoxonase (PON1) in Health and Disease: Basic and Clinical Aspects. None Costa LG, Furlong CE Costa LG, Furlong CE. Paraoxonase (PON1) in Health and Disease: Basic and Clinical Aspects. 2002; Boston, Kluwer Academic Publishers. R831709 (2005)
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    Book Gene-Environment Interactions: Fundamentals of Ecogenetics. None Costa LG, Eaton DL, eds. Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. Hoboken, NJ: Wiley, 2006. R831709 (2006)
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  • Book PON1 and organophosphate toxicity. Paraoxonase (PON1) in Health and Disease: Basic and Clinical Aspects. None Costa L, Li W, Furlong C Costa L, Li W, Furlong C. PON1 and organophosphate toxicity. Paraoxonase(PON1) in Health and Disease: Basic and Clinical Aspects. 2002; Boston, Kluwer Academic Press: 165-183. R831709 (2005)
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    Book PON1 polymorphisms. Paraoxonase (PON1) in Health and Disease: Basic and Clinical Aspects. None Costa L, Furlong C Costa L, Furlong C. PON1 polymorphisms. Paraoxonase (PON1) in Health and Disease: Basic and Clinical Aspects. Boston, Kluwer Academic Press: 53-77. R831709 (2005)
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    Book In vitro models for evaluating developmenta toxicity. None Lewandowski T, Ponce R Lewandowski T, Ponce R. In vitro models for evaluating developmenta toxicity. In Vitro Toxicology. S. Gad. New York, Raven Press, Ltd. 2000. R825358 (Final)
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    Book Chapter Paraoxonase polymorphisms and susceptibility to organophosphate pesticides: implications for pesticide applicators. None Battuello K, Furlong C, Fenske R, Austin M, Burke W Battuello K, Furlong C, Fenske R, Austin M, Burke W. Paraoxonase polymorphisms and susceptibility to organophosphate pesticides: implications for pesticide applicators. In: Khoury MJ, Little J, Burke W, eds. Human Genome Epidemiology. Oxford, UK: Oxford University Press, 2003. R831709 (2005)
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    Book Chapter Perspectives in PON1 research. Chapter 10. None Costa LG, Furlong CE Costa LG, Furlong CE. Perspectives in PON1 research. Chapter 10. In: Costa LG, Furlong CE, eds. Paraoxonase (PON1) in Health and Disease: Basic and Clinical Aspects. Boston, MA: Kluwer Academic Publishers, 2002. R826886C002 (2002)
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  • Book Chapter Paraoxonase (PON1) polymorphisms. None Costa LG, Furlong CE Costa LG, Furlong CE. Paraoxonase (PON1) polymorphisms. In: Fuchs J, Podda M, eds. Encyclopedia of Medical Genomics and Proteomics. New York, NY: Marcel Dekker, 2004, pp. 965-969. R831709C002 (2004)
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    Book Chapter Paraoxonase (PON1) polymorphisms and toxicity of organophosphates. None Costa LG, Cole TB, Vitalone A, Furlong CE Costa LG, Cole TB, Vitalone A, Furlong CE. Paraoxonase (PON1) polymorphisms and toxicity of organophosphates. In: Gupta RC, ed. Toxicology of Organophosphates & Carbamate Compounds. San Diego, CA: Academic Press, 2005, Chapter 18. R831709C002 (2005)
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    Book Chapter Paraoxonase butyrylcholinesterase, and epoxide hydrolase. None Costa LG, Cole TB, Geiss GK, Furlong CE Costa LG, Cole TB, Geiss GK, Furlong CE. Paraoxonase butyrylcholinesterase, and epoxide hydrolase. In: Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. Hoboken, NJ: John Wiley & Sons, Inc., 2006, Part II, Chapter 9. R831709 (2005)
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    Book Chapter Chapter 11. None Costa LG Costa LG. Receptors and ion channels. In: Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. Hoboken, NJ: John Wiley & Sons, 2006. R831709 (2006)
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    Book Chapter Chapter 9. None Costa LG, Cole TB, Geiss GK, Furlong CE Costa LG, Cole TB, Geiss GK, Furlong CE. Paraoxonase, butyrylcholinesterase, and epoxide hydrolase. In: Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. Hoboken, NJ: John Wiley & Sons, 2006. R831709 (2006)
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    Book Chapter Paraoxonase (PON1) polymorphisms and toxicity of organophosphates. None Costa LG, Cole TB, Vitalone A, Furlong CE Costa LG, Cole TB, Vitalone A, Furlong CE. Paraoxonase polymorphisms and toxicity of organophosphates. In: Gupta RC, ed. Toxicology of Organophosphates & Carbamate Compounds. San Diego, CA: Elsevier Inc., 2006. R831709 (2005)
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  • Full-text: Elsevier - Summary/Table of Contents
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  • Book Chapter Paraoxonase, butyrylcholinesterase, and epoxide hydrolase. None Costa LG, Cole TB, Geiss GK, Furlong CE Costa LG, Cole TB, Geiss GK, Furlong CE. Paraoxonase, butyrylcholinesterase, and epoxide hydrolase. In: Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. Hoboken, NJ: Wiley, 2006. R831709 (2007)
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  • Book Chapter Receptors and ion channels. None Costa LG Costa LG. Receptors and ion channels. In: Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. Hoboken, NJ: Wiley, 2006. R831709 (2005)
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  • Book Chapter Toxic effects of pesticides. None Costa LG Costa LG. Toxic effects of pesticides. In: Klaassen CD, ed. Casarett & Doull’s Toxicology: The Basic Science of Poisons, 7th Edition. New York, NY: McGraw-Hill, 2007, pp. 883-932. R831709 (2005)
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  • Book Chapter Facilitating regulatory design and stakeholder participation: The FERET template with an application to the Clean Air Act. None Farrow, RS, Wong E, Ponce RA, Faustman EM Farrow, RS, Wong E, Ponce RA, Faustman EM. Facilitating regulatory design and stakeholder participation: The FERET template with an application to the Clean Air Act. Improving Regulation: Cases in Environment, Health and Safety. P. Fischbeck and S. Farrow.2001; Washington, DC, Resources for the Future Press: 429-442. R831709 (2005)
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    Book Chapter Experimental approaches to evaluate mechanisms of developmental toxicity. None Faustman EM, Ponce RA, Seeley MR, Whittaker SG Faustman EM, Ponce RA, Seeley MR, Whittaker SG. Experimental approaches to evaluate mechanisms of developmental toxicity. In: Hood RD, ed. Developmental and Reproductive Toxicology: A Practical Approach. Boca Raton, FL: CRC Press, Inc., 2004. R831709 (2005)
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    Book Chapter Gene-Environment Interactions: Fundamentals of Ecogenetics None Faustman EM, Omenn GS Faustman EM, Omenn GS. Risk assesssment and the impact of ecogenetics. In: Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. 2006; Hoboken, NJ: John Wiley & Sons. R831709 (2005)
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  • Book Chapter Understanding the significance of genetic variability in the human PON1 gene. None Furlong C, Li W, Cole T, Mapsa R, Richter R, Jarvik G, Shih D, Tward A, Lusis A, Costa L Furlong C, Li W, Cole T, Mapsa R, Richter R, Jarvik G, Shih D, Tward A, Lusis A, Costa L. Understanding the significance of genetic variability in the human PON1 gene. In: Valdes JJ, Sekowski JW, eds. Toxicogenomics and Proteomics. Amsterdam, Netherlands: IOS Press, 2004. R831709C002 (2004)
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    Book Chapter Neurodegenerative diseases. None Kelada SN, Checkoway H, Costa LG Kelada SN, Checkoway H, Costa LG. Neurodegenerative diseases. In: Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. Hoboken, NJ: Wiley, 2006. R831709 (2005)
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  • Book Chapter Identifying mechanisms of developmental toxicity: Application of tools from molecular biology. None Kirchner S, Faustman E Kirchner S, Faustman E. Identifying mechanisms of developmental toxicity: Application of tools from molecular biology. Molecular Biology and Toxic Response. Puga and K. Wallace. 1998; Washington, DC, Taylor and Francis Publishers: 411-437. R831709 (2005)
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    Book Chapter Determination of paraoxonase 1 status and genotypes at specific polymorphic sites. None Richter RJ, Jampsa RL, Jarvik GP, Costa LG, Furlong CE Richter RJ, Jampsa RL, Jarvik GP, Costa LG, Furlong CE. Determination of paraoxonase 1 status and genotypes at specific polymorphic sites. In: Maines M, Costa LG, Hodgson E, Reed DJ, eds. Current Protocols in Toxicology. New York, NY: John Wiley & Sons, Inc., 2004, pp. 1-19. R831709C002 (2004)
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    Journal Article Quantitative mechanistically based dose-response modeling with endocrine-active compounds. ENVIRONMENTAL HEALTH PERSPECTIVES Andersen ME, Conolly RB, Faustman EM, Kavlock RJ, Portier CJ, Sheehan DM, Wier PJ, Ziese L Andersen ME, Conolly RB, Faustman EM, Kavlock RJ, Portier CJ, Sheehan DM, Wier PJ, Ziese L. Quantitative mechanistically based dose-response modeling with endocrine-active compounds. Environmental Health Perspectives 1999;107(4):631-8. R831709 (2005)
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    Journal Article Human variability in mercury toxicokinetics and steady state biomarker ratios. None Bartell SM, Ponce RA, Sanga RN, Faustman EM Bartell SM, Ponce RA, Sanga RN, Faustman EM. Human variability in mercury toxicokinetics and steady state biomarker ratios. Environmental Research 2000;84(2):127-32. R831709 (2005)
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    Journal Article Risk estimation and value-of-information analysis for three proposed genetic screening programs for chronic beryllium disease prevention RISK ANALYSIS Bartell SM, Ponce RA, Takaro TK, Zerbe RO, Omenn GS, Faustman EM Bartell SM, Ponce RA, Takaro TK, Zerbe RO, Omenn GS, Faustman EM. Risk estimation and value-of-information analysis for three proposed genetic screening programs for chronic beryllium disease prevention. Risk Analysis 2000;20(1):87-99. R825173 (1999)
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    Journal Article Glutamate cysteine ligase catalytic subunit promoter polymorphisms and associations with type 1 diabetes age-at-onset and GAD65 autoantibody levels. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES Bekris LM, Shephard C, Janer M, Graham J, McNeney B, Shin J, Zarghami M, Griffith W, Farin F, Kavanagh TJ, Lernmark A Bekris LM, Shephard C, Janer M, Graham J, McNeney B, Shin J, Zarghami M, Griffith W, Farin F, Kavanagh TJ, Lernmark A. Glutamate cysteine ligase catalytic subunit promoter polymorphisms and associations with type 1 diabetes age-at-onset and GAD65 autoantibody levels. Experimental and Clinical Endocrinology & Diabetes 2007;115(4):221-228. R831709 (2005)
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  • Journal Article Harmonization of cancer and non-cancer risk assessment: proceedings of a consensus-building workshop. TOXICOLOGICAL SCIENCES Bogdanffy MS, Daston G, Faustman EM, Kimmel CA, Kimmel GL, Seed J, Vu V Bogdanffy MS, Daston G, Faustman EM, Kimmel CA, Kimmel GL, Seed J, Vu V. Harmonization of cancer and non-cancer risk assessment: proceedings of a consensus-building workshop. Toxicological Sciences 2001;61(1):18-31. R831709 (2005)
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    Journal Article Analysis of paraoxonase (PON1) L55M status requires both genotype and phenotype. PHARMACOGENETICS Brophy VH, Jarvik GP, Richter RJ, Rozek LS, Schellenberg GD, Furlong CE Brophy VH, Jarvik GP, Richter RJ, Rozek LS, Schellenberg GD, Furlong CE. Analysis of paraoxonase (PON1) L55M status requires both genotype and phenotype. Pharmacogenetics 2000;10:453-60. R831709 (2005)
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    Journal Article Effects of 5’ regulatory-region polymorphisms on paraoxonase-gene (PON1) expression. AMERICAN JOURNAL OF HUMAN GENETICS Brophy VH, Jampsa RL, Clendenning JB, McKinstry LA, Jarvik GP, Furlong CE Brophy VH, Jampsa RL, Clendenning JB, McKinstry LA, Jarvik GP, Furlong CE. Effects of 5’ regulatory-region polymorphisms on paraoxonase-gene (PON1) expression. American Journal of Human Genetics 2001;68(6):1428-1436. R826886C002 (2001)
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  • Journal Article Paraoxonase (PON1) regulatory region polymorphisms affect activity level. TOXICOLOGICAL SCIENCES Brophy VH, Jampsa RL, Clendenning JB, McKinstry LA, Jarvik GP, Furlong CE Brophy VH, Jampsa RL, Clendenning JB, McKinstry LA, Jarvik GP, Furlong CE.Paraoxonase (PON1) regulatory region polymorphisms affect activity level. Toxicological Sciences 2001;60(Supp):51. R831709 (2005)
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    Journal Article Polymorphisms in the human paraoxonase (PON1) promoter. PHARMACOGENETICS Brophy V H, Hastings MD, Clendenning JB, Richter RJ, Jarvik GP, Furlong CE Brophy V H, Hastings MD, Clendenning JB, Richter RJ, Jarvik GP, Furlong CE. Polymorphisms in the human paraoxonase (PON1) promoter. Pharmacogenetics 2001;11(1):77-84. R826886C002 (2001)
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  • Journal Article The effects of methylmercury exposure on visual and auditory functions in nonhuman primates. THE TOXICOLOGIST Burbacher TM, Grant KS, Gilbert SG, Rice DC Burbacher TM, Grant KS, Gilbert SG, Rice DC. The effects of methylmercury exposure on visual and auditory functions in nonhuman primates. The Toxicologist 1999;19:243. R831709 (2005)
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    Journal Article Methods for studying nonhuman primates in neurobehavioral toxicology and teratology. NEUROTOXICOLOGY AND TERATOLOGY Burbacher TM, Grant KS Burbacher TM, Grant KS. Methods for studying nonhuman primates in neurobehavioral toxicology and teratology. Neurotoxicology and Teratology 2000;22(4):475-86. R831709 (2005)
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    Journal Article Developmental neurotoxicity of toluene: in vivo and in vitro effects on astroglial cells. DEVELOPMENTAL NEUROSCIENCE Burry M, Guizzetti M, Oberdoerster J, Costa LG Burry M, Guizzetti M, Oberdoerster J, Costa LG. Developmental neurotoxicity of toluene: in vivo and in vitro effects on astroglial cells. Developmental Neuroscience 2003;25(1):14-9. R831709 (2005)
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    Journal Article Differential regulation of mitogen-activated protein kinases ERK1/2 and ERK5 by neurotrophins, neuronal activity, and cAMP in neurons. THE JOURNAL OF NEUROSCIENCE Cavanaugh JE, Ham J, Hetman M, Poser S, Yan C, Zhengui X Cavanaugh JE, Ham J, Hetman M, Poser S, Yan C, Zhengui X. Differential regulation of mitogen-activated protein kinases ERK1/2 and ERK5 by neurotrophins, neuronal activity, and cAMP in neurons. The Journal of Neuroscience 2001;21(2):434-443. R831709 (2005)
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    Journal Article Genetically determined susceptibility to organophosphorus insecticides and nerve agents: developing a mouse modelfor the human PON1 polymorphism. NEUROTOXICOLOGY CE Furlong CE, Li WF, Costa LG, Richter RJ, Shih DM, Lusis AJ CE Furlong CE, Li WF, Costa LG, Richter RJ, Shih DM, Lusis AJ. Genetically determined susceptibility to organophosphorus insecticides and nerve agents: developing a mouse modelfor the human PON1 polymorphism. Neurotoxicology 1998;19(4-5):645-50. R831709 (2005)
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    Journal Article DNA elements of the type 1 adenylyl cyclase gene locus enhance reporter gene expression in neurons and pinealocytes. EUROPEAN JOURNAL OF NEUROSCIENCE Chan GK, Lernmark U, Xia Z, Storm DR Chan GCK, Lernmark U, Xia Z, Storm DR. DNA elements of the type 1 adenylyl cyclase gene locus enhance reporter gene expression in neurons and pinealocytes. European Journal of Neuroscience 2001;13(11):2054-2066. R831709 (2005)
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    Journal Article Allergenic proteins are fragmented in low concentrations of sodium hypochlorite. CLINICAL AND EXPERIMENTAL ALLERGY Chen P, Eggleston PA Chen P, Eggleston PA. Allergenic proteins are fragmented in low concentrations of sodium hypochlorite. Clinical and Experimental Allergy 2001;31:1086-93. R831709 (2005)
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    Journal Article Inhibition of paraoxonase (PON1) by heavy metals. TOXICOLOGICAL SCIENCES Cole TB, Li WF, Richter RJ, Furlong CE, Costa LG Cole TB, Li WF, Richter RJ, Furlong CE, Costa LG. Inhibition of paraoxonase (PON1) by heavy metals. Toxicological Sciences 2002;66(Suppl 1):312. R831709 (2005)
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    Journal Article Contribution of paraoxonase (PON1) levels and Q192R genotype to organophosphate detoxication: evidence from humans and "humanized" transgenic mice. TOXICOLOGICAL SCIENCES Cole TB, Walter BJ Cole, TB, Walter, BJ. Contribution of paraoxonase (PON1) levels and Q192R genotype to organophosphate detoxication: evidence from humans and "humanized" transgenic mice. Toxicological Sciences 2003;72(Suppl 1):100. R831709 (2005)
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    Journal Article Expression of human paraoxonase (PON1) during development. PHARMACOGENETICS Cole TB, Jampsa RL, Walter BJ, Arndt TL, Richter RJ, Shih DM, Tward A, Lusis AJ, Jack RM, Costa LG, Furlong CE Cole TB, Jampsa RL, Walter BJ, Arndt TL, Richter RJ, Shih DM, Tward A, Lusis AJ, Jack RM, Costa LG, Furlong CE. Expression of human paraoxonase (PON1) during development. Pharmacogenetics 2003;13:357-64. R831709 (2005)
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    Journal Article Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism. None Cole TB, Walter BJ, Shih DM, Tward AD, Lusis AJ, Timchalk C, Richter RJ, Costa LG, Furlong CE Cole TB, Walter BJ, Shih DM, Tward AD, Lusis AJ, Timchalk C, Richter RJ, Costa LG, Furlong CE. Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism. Pharmacogenetics and Genomics 2005;15(8):589-598. R831709 (2005)
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    Journal Article Activities and organophosphate exposures: response. ENVIRONMENTAL HEALTH PERSPECTIVES Coronado GD, Thompson B, Strong L, Griffith WC, Islas I Coronado GD, Thompson B, Strong L, Griffith WC, Islas I. Activities and organophosphate exposures: response. Environmental Health Perspectives 2004;112(13):A725-A726. R831709 (2005)
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    Journal Article Agricultural task and exposure to organophosphate pesticides among farmworkers. ENVIRONMENTAL HEALTH PERSPECTIVES Coronado GD, Thompson B, Strong L, Griffith WC, Islas I Coronado GD, Thompson B, Strong L, Griffith WC, Islas I. Agricultural task and exposure to organophosphate pesticides among farmworkers. Environmental Health Perspectives 2004;112:142-7. R831709 (2005)
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    Journal Article Children’s exposure to OP pesticides: response to Fenske et al. ENVIRONMENTAL HEALTH PERSPECTIVES Coronado GD, Thompson B, Griffith WC Coronado GD, Thompson B, Griffith WC. Children’s exposure to OP pesticides: response to Fenske et al. Environmental Health Perspectives 2004;112(15):A866. R831709C003 (2005)
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    Journal Article Organophosphate pesticide exposure and work in pome fruit: evidence for the take-home pesticide pathway. ENVIRONMENTAL HEALTH PERSPECTIVES Coronado GD, Vigoren EM, Thompson B, Griffith WC, Faustman EM Coronado GD, Vigoren EM, Thompson B, Griffith WC, Faustman EM. Organophosphate pesticide exposure and work in pome fruit: evidence for the take-home pesticide pathway. Environmental Health Perspectives 2006;114(7):999-1006. R831709 (2005)
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  • Journal Article Children's Exposure to OP Pesticides: Response to Fenske et al. ENVIRONMENTAL HEALTH PERSPECTIVES Coronado G, Thompson B Coronado G, Thompson B. Children's Exposure to OP Pesticides: Response to Fenske et al. Environmental Health Perspectives 2004;112(15): A866. R831709 (2005)
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    Journal Article The role of paraoxonase (PON1) in the detoxication of organophosphates and its human polymorphism. CHEMICO-BIOLOGICAL INTERACTIONS Costa LG, Li WF, Richter RJ, Shih DM, Lusis A, Furlong CE Costa LG, Li WF, Richter RJ, Shih DM, Lusis A, Furlong CE. The role of paraoxonase (PON1) in the detoxication of organophosphates and its human polymorphism. Chemico-Biological Interactions 1999;119-120:429-438. R826886C002 (2000)
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  • Journal Article The emerging field of ecogenetics. NEUROTOXICOLOGY Costa LG Costa LG. The emerging field of ecogenetics. NeuroToxicology 2000;21(1-2):85-89. R826886C002 (2000)
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  • Journal Article Intracellular signal transduction pathways as targets for neurotoxicants. TOXICOLOGY Costa LG, Guizzetti M, Lu H, Bordi F, Vitalone A, Tita B, Palmery P, Silvestrini B Costa LG, Guizzetti M, Lu H, Bordi F, Vitalone A, Tita B, Palmery P, Silvestrini B. Intracellular signal transduction pathways as targets for neurotoxicants. Toxicology 2001;160(1-3):19-26. R831709 (2005)
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    Journal Article Pesticide exposure: differential risk for neurotoxic outcomes due to enzyme polymorphisms. CLINICS IN OCCUPATIONAL AND ENVIRONMENTAL MEDICINE Costa LG Costa LG. Pesticide exposure: differential risk for neurotoxic outcomes due to enzyme polymorphisms. Clinics in Occupational and Environmental Medicine 2001;1:511-523. R831709 (2005)
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    Journal Article Developmental neurotoxicity: do similar phenotypes indicate a common mode of action? A comparison of fetal alcohol syndrome, toluene embryopathy and maternal phenylketonuria. TOXICOLOGY LETTERS Costa LG, Guizzetti M, Burry M, Oberdoerster J Costa LG, Guizzetti M, Burry M, Oberdoerster J. Developmental neurotoxicity: do similar phenotypes indicate a common mode of action? A comparison of fetal alcohol syndrome, toluene embryopathy and maternal phenylketonuria. Toxicology Letters 2002;127(1-3):197-205. R831709 (2005)
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    Journal Article Functional genomic of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism. ANNUAL REVIEW OF MEDICINE Costa LG, Cole TB, Jarvik GP, Furlong CE Costa LG, Cole TB, Jarvik GP, Furlong CE. Functional genomic of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism. Annual Review of Medicine 2003;54:371-92. R831709 (2005)
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    Journal Article Paraoxonase (PON1) as a biomarker of susceptibility for organophosphate toxicity. BIOMARKERS Costa LG, Richter RJ, Li W-F, Cole T, Guizzetti M, Furlong CE Costa LG, Richter RJ, Li W-F, Cole T, Guizzetti M, Furlong CE. Paraoxonase (PON1) as a biomarker of susceptibility for organophosphate toxicity. Biomarkers 2003;8(1):1-12. R826886C002 (2002)
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  • Journal Article Polymorphisms of paraoxonase (PON1) and their significance in clinical toxicology of organophosphates. JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY Costa LG, Cole TB, Furlong CE Costa LG, Cole TB, Furlong CE. Polymorphisms of paraoxonase (PON1) and their significance in clinical toxicology of organophosphates. Journal of Toxicology-Clinical Toxicology 2003;41:37-45. R831709 (2005)
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    Journal Article Developmental neuropathology of environmental agents. ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY Costa LG, Aschner M Costa LG, Aschner M. Developmental neuropathology of environmental agents. Annual Review of Pharmacology and Toxicology 2004;44:87-110. R831709 (2005)
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    Journal Article Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity. CLINICA CHIMICA ACTA Costa LG, Cole TB, Vitalone A, Furlong CE Costa LG, Cole TB, Vitalone A, Furlong CE. Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity. Clinica Chimica Acta 2005;352(1-2):37-47. R831709 (2005)
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    Journal Article Modulation of paraoxonase (PON1) activity. BIOCHEMICAL PHARMACOLOGY Costa LG, Vitalone A, Cole TB, Furlong CE Costa LG, Vitalone A, Cole TB, Furlong CE. Modulation of paraoxonase (PON1) activity. Biochemical Pharmacology 2005;69(4):541-550. R831709 (2005)
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    Journal Article Paraoxonase (PON1): from toxicology to cardiovascular medicine. None Costa LG, Cole TB, Furlong CE Costa LG, Cole TB, Furlong CE. Paraoxonase (PON1): from toxicology to cardiovascular medicine. Acta Biomed Ateneo Parmense 2005;76(Suppl 2):50-7. R831709 (2005)
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    Journal Article Current issues in organophosphate toxicology. CLINICA CHIMICA ACTA Costa LG Costa LG. Current issues in organophosphate toxicology. Clinica Chimica Acta 2006;366(1-2):1-13. R831709 (2005)
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  • Journal Article Gene-environment interactions: paraoxonase (PON1) and sensitivity to organophosphate toxicity. None Costa LG, Cole TB, Furlong CE Costa LG, Cole TB, Furlong CE. Gene-environment interactions: paraoxonase (PON1) and sensitivity to organophosphate toxicity. Lab Medicine 2006;37(2):109-113. R831709 (2005)
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    Journal Article Neurotoxicity of pesticides:a brief review. FRONTIERS IN BIOSCIENCE Costa LG, Giordano G, Guizzetti M, Vitalone A Costa LG, Giordano G, Guizzetti M, Vitalone A. Neurotoxicity of pesticides: a brief review. Frontiers in Bioscience 2008;13(4):1240-1249. R831709 (2005)
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  • Journal Article Evaluation of take-home organophosphorus pesticide exposure among agricultural workers and their children. ENVIRONMENTAL HEALTH PERSPECTIVES Curl CL, Fenske RA, Kissel JC, Shirai JH, Moate TW, Griffith W, Coronado G, Thompson B Curl CL, Fenske RA, Kissel JC, Shirai JH, Moate TW, Griffith W, Coronado G, Thompson B. Evaluation of take-home organophosphorus pesticide exposure among agricultural workers and their children. Environmental Health Perspectives 2002;110(12):A787-A792. R826886C003 (2001)
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  • Journal Article Organophosphorus pesticide exposure of urban and suburban preschool children with organic and conventional diets. ENVIRONMENTAL HEALTH PERSPECTIVES Curl CL, Fenske RA, Elgethun K Curl CL, Fenske RA, Elgethun K. Organophosphorus pesticide exposure of urban and suburban preschool children with organic and conventional diets. Environmental Health Perspectives 2003;111:377-82. R831709 (2005)
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    Journal Article Nuclear waste transportation: case studies of identifying stakeholder risk information needs. ENVIRONMENTAL HEALTH PERSPECTIVES Drew CH, Grace DA, Silbernagel SM, Hemmings ES, Smith A, Griffith WC, Takaro TK, Faustman EM Drew CH, Grace DA, Silbernagel SM, Hemmings ES, Smith A, Griffith WC, Takaro TK, Faustman EM. Nuclear waste transportation: case studies of identifying stakeholder risk information needs. Environmental Health Perspectives 2003;111:263-72. R831709 (2005)
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    Journal Article Clinical trials of allergen avoidance in established asthma. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY Eggleston PA

    Eggleston PA. Clinical trials of allergen avoidance in established asthma. Journal of Allergy and Clinical Immunology 2001;108(5):685-687.

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    Journal Article Methods and effectiveness of indoor environmental control. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY Eggleston PA

    Eggleston PA. Methods and effectiveness of indoor environmental control. Annals of Allergy Asthma & Immunology 2001;87(6 Suppl 3):44-47.

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    Journal Article Time-location analysis for exposure assessment studies of children using a novel global positioning system instrument. ENVIRONMENTAL HEALTH PERSPECTIVES Elgethun K, Fenske RA, Yost MG, Palcisko GJ Elgethun K, Fenske RA, Yost MG, Palcisko GJ. Time-location analysis for exposure assessment studies of children using a novel global positioning system instrument. Environmental Health Perspectives 2003;111(1):115-122. R826886C004 (2002)
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  • Journal Article Comparison of GPS tracking to the NHEXAS diary timeline for time-location measurement of children. JOURNAL OF EXPOSURE ANALYSIS AND ENVIRONMENTAL EPIDEMIOLOGY Elgethun K, Yost MG, Fitzpatrick CT, Nyerges TL, Fenske RA Elgethun K, Yost MG, Fitzpatrick CT, Nyerges TL, Fenske RA. Comparison of GPS tracking to the NHEXAS diary timeline for time-location measurement of children. Journal of Exposure Analysis and Environmental Epidemiology 2007;17:196-206. R831709 (2005)
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    Journal Article Comparison of global positioning system (GPS) tracking and parent-report diaries to characterize children's time–location patterns None Elgethun K, Yost MG, Fitzpatrick CTE, NyergesTL, Fenske RA. Elgethun K, Yost MG, Fitzpatrick CTE, NyergesTL, Fenske RA. Comparison of global positioning system (GPS) tracking and parent-report diaries to characterize children's time–location patterns. Journal of Exposure Science and Environmental Epidemiology 2007;17(2):196-206. R831709 (2005)
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  • Journal Article Association of in utero organophosphate pesticide exposure and fetal growth and length of gestation in an agricultural population. ENVIRONMENTAL HEALTH PERSPECTIVES Eskenazi B, Harley K, Bradman A, Weltzien E, Jewell NP, Barr DB, Furlong CE, Holland NT Eskenazi B, Harley K, Bradman A, Weltzien E, Jewell NP, Barr DB, Furlong CE, Holland NT. Association of in utero organophosphate pesticide exposure and fetal growth and length of gestation in an agricultural population. Environmental Health Perspectives 2004;112(10):1116-1124. R831709C002 (2004)
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  • Journal Article Methodologic and logistic issues in conducting longitudinal birth cohort studies: lessons learned from the Centers for Children’s Environmental Health and Disease Prevention Research. ENVIRONMENTAL HEALTH PERSPECTIVES Eskenazi B, Gladstone EA, Berkowitz GS, Drew CH, Faustman EM, Holland NT, Lanphear B, Meisel SJ, Perera FP, Rauh VA, Sweeney A, Whyatt RM, Yolton K Eskenazi B, Gladstone EA, Berkowitz GS, Drew CH, Faustman EM, Holland NT, Lanphear B, Meisel SJ, Perera FP, Rauh VA, Sweeney A, Whyatt RM, Yolton K. Methodologic and logistic issues in conducting longitudinal birth cohort studies: lessons learned from the Centers for Children’s Environmental Health and Disease Prevention Research. Environmental Health Perspectives 2005;113(10):1419-1429. R827027 (2002)
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  • Journal Article Biologically based dose-response models for developmental toxicants: lessons from methylmercury. INHALATION TOXICOLOGY Faustman EM, Lewandowski TA, Ponce RA, Bartell SM Faustman EM, Lewandowski TA, Ponce RA, Bartell SM. Biologically based dose-response models for developmental toxicants: lessons from methylmercury. Inhalation Toxicology 1999;11(6-7):559-572. R825173 (1999)
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    Journal Article Mechanisms underlying children’s susceptibility to environmental toxicants. ENVIRONMENTAL HEALTH PERSPECTIVES Faustman EM, Silbernagel SM, Fenske RA, Burbacher TM, Ponce RA Faustman EM, Silbernagel SM, Fenske RA, Burbacher TM, Ponce RA. Mechanisms underlying children’s susceptibility to environmental toxicants. Environmental Health Perspectives 2000;108(Suppl 1):13-21. R825173 (1999)
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  • Journal Article Investigations of methylmercury-induced alterations in neurogenesis. ENVIRONMENTAL HEALTH PERSPECTIVES Faustman EM, Ponce RA, Ou YC, Mendoza MA, Lewandowski T, Kavanagh T Faustman EM, Ponce RA, Ou YC, Mendoza MA, Lewandowski T, Kavanagh T. Investigations of methylmercury-induced alterations in neurogenesis. Environmental Health Perspectives 2002;110(Suppl 5):859-64. R831709 (2005)
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    Journal Article Modeling developmental processes in animals: Applications in neurodevelopmental toxicology. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY Faustman EM, Gohlke, JM, Judd NL, Lewandowski TA, Bartell SA, Griffith WC Faustman EM, Gohlke, JM, Judd NL, Lewandowski TA, Bartell SA, Griffith WC. Modeling developmental processes in animals: Applications in neurodevelopmental toxicology. Environmental Toxicology and Pharmacology 2005;19(3):615-624. R831709 (2005)
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  • Journal Article Biologically based pesticide dose estimates for children in an agricultural community. ENVIRONMENTAL HEALTH PERSPECTIVES Fenske RA, Kissel JC, Lu C, Kalman DA, Simcox NJ, Allen EH, Keifer MC Fenske RA, Kissel JC, Lu C, Kalman DA, Simcox NJ, Allen EH, Keifer MC. Biologically based pesticide dose estimates for children in an agricultural community. Environmental Health Perspectives 2000;108(6):515-520. R826886C004 (2001)
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  • Journal Article Strategies for assessing children’s organophosphorus pesticide exposures in agricultural communities. JOURNAL OF EXPOSURE ANALYSIS AND ENVIRONMENTAL EPIDEMIOLOGY Fenske RA, Lu C, Simcox NJ, Loewenherz C, Touchstone J, Moate TF, Allen EH, Kissel JC Fenske RA, Lu C, Simcox NJ, Loewenherz C, Touchstone J, Moate TF, Allen EH, Kissel JC. Strategies for assessing children’s organophosphorus pesticide exposures in agricultural communities. Journal of Exposure Analysis and Environmental Epidemiology 2000;10(6 Suppl 2):662-671. R825171 (2000)
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  • Journal Article Assessment of organophosphorous pesticide exposures in the diets of preschool children in Washington State. JOURNAL OF EXPOSURE ANALYSIS AND ENVIRONMENTAL EPIDEMIOLOGY Fenske RA, Kedan G, Lu C, Fisker-Andersen JA, Curl CL Fenske RA, Kedan G, Lu C, Fisker-Andersen JA, Curl CL. Assessment of organophosphorous pesticide exposures in the diets of preschool children in Washington State. Journal of Exposure Analysis and Environmental Epidemiology 2002;12(1):21-8. R831709 (2005)
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    Journal Article Children's exposure to chlorpyrifos and parathion in an agricultural community in central Washington state. ENVIRONMENTAL HEALTH PERSPECTIVES Fenske RA, Lu C, Barr D, Needham L Fenske RA, Lu C, Barr D, Needham L. Children's exposure to chlorpyrifos and parathion in an agricultural community in central Washington state. Environmental Health Perspectives 2002;110(5):549-553. R831709 (2005)
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    Journal Article Lessons learned for the assessment of children’s pesticide exposure: critical sampling and analytical issues for future studies. ENVIRONMENTAL HEALTH PERSPECTIVES Fenske RA, Bradman A, Whyatt RM, Wolff MS, Barr DB Fenske RA, Bradman A, Whyatt RM, Wolff MS, Barr DB. Lessons learned for the assessment of children’s pesticide exposure: critical sampling and analytical issues for future studies. Environmental Health Perspectives 2005;113(10):1455-1462. R827027 (2002)
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  • Journal Article Biologic monitoring to characterize organophosphorus pesticide exposure among children and workers: an analysis of recent studies in Washington State. ENVIRONMENTAL HEALTH PERSPECTIVES Fenske RA, Lu C, Curl CL, Shirai JH, Kissel JC Fenske RA, Lu C, Curl CL, Shirai JH, Kissel JC. Biologic monitoring to characterize organophosphorus pesticide exposure among children and workers: an analysis of recent studies in Washington State. Environmental Health Perspectives 2005;113:1651-7. R831709 (2005)
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    Journal Article Taxol induces apoptosis in cortical neurons by a mechanism independent of Bcl-2 phosphorylation. THE JOURNAL OF NEUROSCIENCE Figueroa-Masot XA, Hetman M, Higgins MJ, Kokot N, Xia Z Figueroa-Masot XA, Hetman M, Higgins MJ, Kokot N, Xia Z. Taxol induces apoptosis in cortical neurons by a mechanism independent of Bcl-2 phosphorylation. The Journal of Neuroscience 2001;21(13):4657-4667. R831709 (2005)
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    Journal Article Genetic and temporal determinants of pesticide sensitivity: role of paraoxonase (PON1). NEUROTOXICOLOGY Furlong CE, Li WF, Richter RJ, Shih DM, Lusis AJ, Alleva E, Costa LG Furlong CE, Li WF, Richter RJ, Shih DM, Lusis AJ, Alleva E, Costa LG. Genetic and temporal determinants of pesticide sensitivity: role of paraoxonase (PON1). NeuroToxicology 2000;21(1-2):91-100. R826886C002 (2000)
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  • Journal Article PON1 status and neurologic symptom complexes in Gulf War veterans. GENOME RESEARCH Furlong CE Furlong CE. PON1 status and neurologic symptom complexes in Gulf War veterans. Genome Research 2000;10(2):153-5. R831709 (2005)
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    Journal Article The PON1 gene and detoxication. NEUROTOXICOLOGY Furlong CE, Li WF, Brophy VH, Jarvik GP, Richter RJ, Shih DM, Lusis AJ, Costa LG Furlong CE, Li WF, Brophy VH, Jarvik GP, Richter RJ, Shih DM, Lusis AJ, Costa LG. The PON1 gene and detoxication. NeuroToxicology 2000;21(4):581-587. R826886C002 (2001)
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  • Journal Article Genetic factors in susceptibility: serum PON1 variation between individuals and species. HUMAN AND ECOLOGICAL RISK ASSESSMENT Furlong CE, Li W-F, Shih DM, Lusis AJ, Richter RJ, Costa LG Furlong CE, Li W-F, Shih DM, Lusis AJ, Richter RJ, Costa LG. Genetic factors in susceptibility:serum PON1 variation between individuals and species. Human and Ecological Risk Assessment 2002;8(1):31-43. R826886C002 (2002)
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  • Journal Article Organophosphate toxicity in mice expressing the human 192R or 192Q isoforms of paraoxonase (PON1). TOXICOLOGICAL SCIENCES Furlong CE, Cole TB, Arndt T, Shih D, Tward A, Lusis A, Costa L Furlong CE, Cole TB, Arndt T, Shih D, Tward A, Lusis A, Costa L. Organophosphate toxicity in mice expressing the human 192R or 192Q isoforms of paraoxonase (PON1). Toxicological Sciences 2002;66:35. R831709 (2005)
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    Journal Article Pharmacogenomic considerations of the paraoxonase polymorphisms. PHARMACOGENETICS Furlong CE, Cole TB, Jarvik GP, Costa LG Furlong CE, Cole TB, Jarvik GP, Costa LG. Pharmacogenomic considerations of the paraoxonase polymorphisms. Pharmacogenomics 2002;3(3):341-348. R826886C002 (2002)
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  • Journal Article New polymorphisms in the human paraoxonase (PON1) gene. TOXICOLOGY SCIENCE Furlong CE, Rieder MJ Furlong CE, Rieder MJ. New polymorphisms in the human paraoxonase (PON1) gene. Toxicology Science 2003;72(Suppl 1):100. R831709 (2005)
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    Journal Article Paraoxonase 1 (PON1) status and risk of insecticide exposure. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY Furlong CE, Cole TB, Walter BJ, Shih DM, Tward A, Lusis AJ, Timchalk C, Richter RJ, Costa LG Furlong CE, Cole TB, Walter BJ, Shih DM, Tward A, Lusis AJ, Timchalk C, Richter RJ, Costa LG. Paraoxonase 1 (PON1) status and risk of insecticide exposure. Journal of Biochemical and Molecular Toxicology 2005;19(3):182-183. R831709 (2005)
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    Journal Article Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants. NEUROTOXICOLOGY Furlong CE, Cole TB, Jarvik GP, Pettan-Brewer C, Geiss GK, Richter RJ, Shih DM, Tward DA, Lusis JA, Costa LG Furlong CE, Cole TB, Jarvik GP, Pettan-Brewer C, Geiss GK, Richter RJ, Shih DM, Tward DA, Lusis JA, Costa LG. Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants. Neurotoxicology 2005;26(4):651-659. R831709 (2005)
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    Journal Article PON1 status of farmworker mothers and children as a predictor of organophosphate sensitivity. PHARMACOGENETICS AND GENOMICS Furlong CE, Holland N, Richter RJ, Bradman A, Ho A, Eskenazi B Furlong CE, Holland N, Richter RJ, Bradman A, Ho A, Eskenazi B. PON1 status of farmworker mothers and children as a predictor of organophosphate sensitivity. Pharmacogenetics and Genomics 2006;16(3):183-190. R831709 (2005)
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  • Journal Article Genetic variability in the cytochrome P450-paraoxonase 1 (PON1) pathway for detoxication of organophosphorus compounds. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY Furlong C Furlong C. Genetic variability in the cytochrome P450-paraoxonase 1 (PON1) pathway for detoxication of organophosphorus compounds. Journal of Biochemical and Molecular Toxicology 2007;21(4):197-205. R831709 (2005)
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    Journal Article Adult responses to a survey of soil contact-related behaviors. JOURNAL OF EXPOSURE ANALYSIS AND ENVIRONMENTAL EPIDEMIOLOGY Garlock TJ, Shirai JH, Kissel JC Garlock TJ, Shirai JH, Kissel JC. Adult responses to a survey of soil contact-related behaviors. Journal of Exposure Analysis and Environmental Epidemiology 1999;9(2):134-42. R831709 (2005)
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    Journal Article Differential modulation of stress and ubiquitination signaling pathways by Cadmium, H202, and serum withdrawal in cultrued mouse fibroblasts. TOXICOLOGIST Garry MR, Sidhu JS Garry MR, Sidhu JS. Differential modulation of stress and ubiquitination signaling pathways by Cadmium, H202, and serum withdrawal in cultrued mouse fibroblasts. Toxicologist 2003;72:311. R831709 (2005)
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    Journal Article Sensitivity of mouse lung fibroblasts heterozygous for GPx4 to oxidative stress. FREE RADICAL BIOLOGY & MEDICINE Garry MR, Kavanagh TJ, Faustman EM, Sidhu JS, Liao R, Ware C, Vlieta PA, Deeb SS Garry MR, Kavanagh TJ, Faustman EM, Sidhu JS, Liao R, Ware C, Vlieta PA, Deeb SS. Sensitivity of mouse lung fibroblasts heterozygous for GPx4 to oxidative stress. Free Radical Biology & Medicine 2008;44(6):1075-87. R831709 (2005)
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    Journal Article p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons. JOURNAL OF CELLUAR BIOLOGY Ghatan S, Larner S, Kinoshita Y, Hetman M, Patel L, Xia Z, Youle RJ, Morrison RS Ghatan S, Larner S, Kinoshita Y, Hetman M, Patel L, Xia Z, Youle RJ, Morrison RS. p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons. Journal of Celluar Biology 2000;150(2):335-47. R831709 (2005)
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    Journal Article Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency. TOXICOLOGY AND APPLIED PHARMACOLOGY Giordano G, Afsharinejad Z, Guizzetti M, Vitalone A, Kavanagh TJ, Costa LG Giordano G, Afsharinejad Z, Guizzetti M, Vitalone A, Kavanagh TJ, Costa LG. Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency. Toxicology and Applied Pharmacology 2007;219(2-3):181-189. R831709 (2005)
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  • Journal Article A computational model for neocortical neuronogenesis predicts ethanol-induced neocortical neuron number deficits. DEVELOPMENTS IN NEUROSCIENCE Gohlke JM, Griffith WC, Bartell SM, Lewandowski TA, Faustman EM Gohlke JM, Griffith WC, Bartell SM, Lewandowski TA, Faustman EM. A computational model for neocortical neuronogenesis predicts ethanol-induced neocortical neuron number deficits. Developments in Neuroscience 2002;24:467-77. R831709 (2005)
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    Journal Article The role of cell death during neocortical neurogenesis and synaptogenesis: implications from a computational model for the rat and mouse. DEVELOPMENTAL BRAIN RESEARCH Gohlke JM, Griffith WC, Faustman EM Gohlke JM, Griffith WC, Faustman EM. The role of cell death during neocortical neurogenesis and synaptogenesis: implications from a computational model for the rat and mouse. Developmental Brain Research 2004;151(1-2):43-54. R831709 (2005)
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    Journal Article A systems-based computational model for dose-response comparisons of two mode of action hypotheses for ethanol-induced neurodevelopmental toxicity. TOXICOLOGY SCIENCE Gohlke JM, Griffith WC, Faustman EM Gohlke JM, Griffith WC, Faustman EM. A systems-based computational model for dose-response comparisons of two mode of action hypotheses for ethanol-induced neurodevelopmental toxicity. Toxicology Science 2005;86:470-84. R831709 (2004)
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    Journal Article Computational models of neocortical neuronogenesis and programmed cell death in the developing mouse, monkey, and human. None Gohlke JM, Griffith WC, Faustman EM Gohlke JM, Griffith WC, Faustman EM. Computational models of neocortical neuronogenesis and programmed cell death in the developing mouse, monkey, and human. Cerebral Cortex 2007;17(10):2433-2442. R831709 (2005)
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  • Journal Article Evaluation of interspecies variability during neocortical neurogenesis using biologically based computational models. TOXICOLOGIST Gohlke J, Griffith W Gohlke J, Griffith W. Evaluation of interspecies variability during neocortical neurogenesis using biologically based computational models. Toxicologist 2003;72: 179. R831709 (2005)
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    Journal Article Stakeholder participation: Experience from the CRESP program. ENVIRONMENTAL EPIDEMIOLOGY AND TOXICOLOGY Goldstein BD, Erdal S, Burger J, Faustman E Goldstein BD, Erdal S, Burger J, Faustman E. Stakeholder participation: Experience from the CRESP program. Environmental Epidemiology and Toxicology2000; 2: 103-111. R831709 (2005)
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    Journal Article Evaluation of cell cycle kinetics in p53 mouse embryonal fibroblasts: Effects of methylmercury. TOXICOLOGIST Gribble E, Mendoza A Gribble E, Mendoza A. Evaluation of cell cycle kinetics in p53 mouse embryonal fibroblasts: Effects of methylmercury. Toxicologist 2003; 72(322). R831709 (2005)
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    Journal Article Kinetic and dynamic characterization of a mouse embryonal mesencephalon neuronal precursor cell culture. BIRTH DEFECTS RESEARCH. PART A, CLINICAL MOLECULAR TERATOLOGY Gribble E, Hong S Gribble E, Hong S. Kinetic and dynamic characterization of a mouse embryonal mesencephalon neuronal precursor cell culture. Birth Defects Research. Part A, Clinical Molecular Teratology 2005;73(5): 301. R831709 (2005)
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    Journal Article Building BBDR models for cell signaling pathways using transgenic animal models. TOXICOLOGIST Griffith W, Gohlke J Griffith W, Gohlke J. Building BBDR models for cell signaling pathways using transgenic animal models. Toxicologist 2003;72: 182. R831709 (2005)
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    Journal Article Systems biology models for integration of diverse studies of the developing neocortex after exposure to low dose radiation from external and internal sources. TOXICOLOGIST Griffith W, DeFrank N Griffith W, DeFrank N. Systems biology models for integration of diverse studies of the developing neocortex after exposure to low dose radiation from external and internal sources. Toxicologist 2006;90: 336. R831709 (2005)
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    Journal Article Effect of organophosphorus insecticides and their metabolites on astroglial cell proliferation. TOXICOLOGY Guizzetti M, Pathak S, Giordano G, Costa LG Guizzetti M, Pathak S, Giordano G, Costa LG. Effect of organophosphorus insecticides and their metabolites on astroglial cell proliferation. Toxicology 2005;215(3):182-190. R831709 (2005)
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  • Journal Article Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular-signal-regulated kinase and phosphatidylinositol-3 kinase. JOURNAL OF BIOLOGICAL CHEMISTRY Hetman M, Kanning K, Cavanaugh JE, Xia Z Hetman M, Kanning K, Cavanaugh JE, Xia Z . Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular-signal-regulated kinase and phosphatidylinositol-3 kinase. Journal of Biological Chemistry1999; (274): 22569-22580. R831709 (2005)
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    Journal Article Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal. THE JOURNAL OF NEUROSCIENCE Hetman M, Cavanaugh JE, Kimelman D, Xia Z Hetman M, Cavanaugh JE, Kimelman D, Xia Z. Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal. The Journal of Neuroscience2000; 20(7):2567-2574. R831709 (2005)
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    Journal Article ERK1/2 antagonizes glycogen synthase kinase-3beta-induced apoptosis in cortical neurons. JOURNAL OF BIOLOGICAL CHEMISTRY Hetman M, Hsuan SL, Habas A, Higgins MJ, Xia Z Hetman M, Hsuan SL, Habas A, Higgins MJ, Xia Z. ERK1/2 antagonizes glycogen synthase kinase-3beta-induced apoptosis in cortical neurons. Journal of Biological Chemistry 277(51):49577-84. R831709 (2005)
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    Journal Article Paraoxonase polymorphisms, haplotypes, and enzyme activity in Latino mothers and newborns. ENVIRONMENTAL HEALTH PERSPECTIVES Holland N, Furlong C, Bastaki M, Richter R, Bradman A, Huen K, Beckman K, Eskenazi B Holland N, Furlong C, Bastaki M, Richter R, Bradman A, Huen K, Beckman K, Eskenazi B. Paraoxonase polymorphisms, haplotypes, and enzyme activity in Latino mothers and newborns. Environmental Health Perspectives 2006;114(7):985-991. R831709 (2005)
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  • Journal Article Refinement of high-throughput 2D-Page technique for the evaluation of ubiquitin-conjugated protein status induced by developmental toxicants. TOXICOLOGIST Hong S, Sidhu J Hong S, Sidhu J. Refinement of high-throughput 2D-Page technique for the evaluation of ubiquitin-conjugated protein status induced by developmental toxicants. Toxicologist 2003;72: 732. R831709 (2005)
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    Journal Article Community-based participatory research: lessons learned from the Centers for Children’s Environmental Health and Disease Prevention Research. ENVIRONMENTAL HEALTH PERSPECTIVES Israel BA, Parker EA, Rowe Z, Salvatore A, Minkler M, Lopez J, Butz A, Mosley A, Coates L, Lambert G, Potito PA, Brenner B, Rivera M, Romero H, Thompson B, Coronado G, Halstead S Israel BA, Parker EA, Rowe Z, Salvatore A, Minkler M, Lopez J, Butz A, Mosley A, Coates L, Lambert G, Potito PA, Brenner B, Rivera M, Romero H, Thompson B, Coronado G, Halstead S. Community-based participatory research: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environmental Health Perspectives 2005;113(10):1463-1471. R826710 (Final)
    R829391 (2004)
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    R831710 (2004)
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  • Journal Article Paraoxonase (PON1) phenotype is a better predictor of vascular disease than is PON1(192) or PON1(55) genotype. ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY Jarvik GP, Rozek LS, Brophy VH, Hatsukami TS , Richter RJ, Schellenberg GD, Furlong CE Jarvik GP, Rozek LS, Brophy VH, Hatsukami TS , Richter RJ, Schellenberg GD, Furlong CE. Paraoxonase (PON1) phenotype is a better predictor of vascular disease than is PON1(192) or PON1(55) genotype. Arteriosclerosis, Thrombosis, and Vascular Biology2000; 20(11): 2441-7. R831709 (2005)
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    Journal Article Novel paraoxonase (PON1) nonsense and missense mutations predicted by functional genomic assay of PON1 status. PHARMACOGENETICS Jarvik GP, Jampsa R, Richter RJ, Carlson CS, Rieder MJ, Nickerson DA, Furlong CE Jarvik GP, Jampsa R, Richter RJ, Carlson CS, Rieder MJ, Nickerson DA, Furlong CE. Novel paraoxonase (PON1) nonsense and missense mutations predicted by functional genomic assay of PON1 status. Pharmacogenetics 2003;13(5):291-295. R831709 (2005)
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    Journal Article A value of information assessment for congener specific analytical techniques for PCBs: do they meet risk assessment needs? None Judd NL, Griffith WC, Kalman DA, Faustman EM Judd NL, Griffith WC, Kalman DA, Faustman EM. A value of information assessment for congener specific analytical techniques for PCBs: do they meet risk assessment needs?Toxicologist2001; 60(1): 256. R831709 (2005)
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    Journal Article Alternative strategies for PCB risk reduction from contaminated seafood: options for children as susceptible populations. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY Judd NL, Griffith WC, Ylitalo GM, Faustman EM Judd NL, Griffith WC, Ylitalo GM, Faustman EM. Alternative strategies for PCB risk reduction from contaminated seafood: options for children as susceptible populations. Bulletin of Environmental Contaminantion and Toxicology 2002;69:847-54. R831709 (2005)
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    Journal Article Evaluation of TEQ Exposure from Fish Consumption Relative to Average Population Total Exposure: Implications for PCB, PCDF, and PCDD Risk Management. TOXICOLOGIST Judd NL, Griffith WC Judd NL, Griffith WC. Evaluation of TEQ Exposure from Fish Consumption Relative to Average Population Total Exposure: Implications for PCB, PCDF, and PCDD Risk Management. Toxicologist 2002; 66(1-5): 105. R831709 (2005)
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    Journal Article A model for optimization of biomarker testing frequency to minimize disease and cost: example of beryllium sensitization testing. RISK ANALYSIS Judd NL, Griffith WC, Takaro T, Faustman EM Judd NL, Griffith WC, Takaro T, Faustman EM. A model for optimization of biomarker testing frequency to minimize disease and cost: example of beryllium sensitization testing. Risk Analysis2003; 23(6): 1211-20. R831709 (2005)
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    Journal Article Assessment of PCB congener analytical methods: do they meet risk assessment needs? Archives of Environmental Contamination and Toxicology2003; 44(1):132-9. None Judd NL, Griffith WC, Kalman DA, Faustman EM Judd NL, Griffith WC, Kalman DA, Faustman EM. Assessment of PCB congener analytical methods: do they meet risk assessment needs? Archives of Environmental Contamination and Toxicology2003; 44(1):132-9. R831709 (2005)
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    Journal Article Challenges in defining background levels for human and ecological risk assessments. HUMAN AND ECOLOGICAL RISK ASSESSMENT Judd NL, Karr JR, Griffith WC, Faustman EM Judd NL, Karr JR, Griffith WC, Faustman EM. Challenges in defining background levels for human and ecological risk assessments.Human and Ecological Risk Assessment2003; 9(7): 1623-1632. R831709 (2005)
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    Journal Article Consideration of cultural and lifestyle factors in defining susceptible populations for environmental disease. TOXICOLOGY Judd NL, Griffith WC, Faustman EM Judd NL, Griffith WC, Faustman EM. Consideration of cultural and lifestyle factors in defining susceptible populations for environmental disease. Toxicology2004; 198(1-3): 121-133. R831709 (2005)
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    Journal Article Contribution of PCB exposure from fish consumption to total dioxin-like dietary exposure. REGULATORY TOXICOLOGY AND PHARMACOLOGY Judd N, Griffith WC, Faustman EM Judd N, Griffith WC, Faustman EM. Contribution of PCB exposure from fish consumption to total dioxin-like dietary exposure. Regulatory Toxicology and Pharmacology 2004;40:125-35. R831709 (2005)
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    Journal Article Glutathione S-transferase M1, T1, and P1 polymorphisms and Parkinson's disease. NEUROSCIENCE LETTERS Kelada SN, Stapleton PL, Farin FM, Bammler TK, Eaton DL, Smith-Weller T, Franklin GM, Swanson PD, Longstreth WT Jr, Checkoway H Kelada SN, Stapleton PL, Farin FM, Bammler TK, Eaton DL, Smith-Weller T, Franklin GM, Swanson PD, Longstreth WT Jr, Checkoway H. Glutathione S-transferase M1, T1, and P1 polymorphisms and Parkinson's disease. Neuroscience Letters 2003;337:5-8. R831709 (2005)
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    Journal Article Comparison of organophosphorus pesticide metabolite levels in single and multiple daily urine samples collected from preschool children in Washington State. JOURNAL OF EXPOSURE ANALYSIS AND ENVIRONMENTAL EPIDEMIOLOGY Kissel JC, Curl CL, Kedan G, Lu C, Griffith W, Barr DB, Needham LL, Fenske RA Kissel JC, Curl CL, Kedan G, Lu C, Griffith W, Barr DB, Needham LL, Fenske RA. Comparison of organophosphorus pesticide metabolite levels in single and multiple daily urine samples collected from preschool children in Washington State. Journal of Exposure Analysis and Environmental Epidemiology 2005;15:164-71. R831709 (2005)
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    Journal Article Attempted reconcilliation of predicted children's exposures to organophosphate pesticides with measured metabolite levels in urine. EPIDEMIOLOGY Kissel J, Kedan G Kissel J, Kedan G. Attempted reconcilliation of predicted children's exposures to organophosphate pesticides with measured metabolite levels in urine.Epidemiology1999;10(4). R831709 (2005)
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    Journal Article Temporal association of children's pesticide exposure and agricultural spraying: Report of a longitudinal biological monitoring study ENVIRONMENTAL HEALTH PERSPECTIVES Koch D, Lu CS, Fisker-Andersen J, Jolley L, Fenske RA Koch D, Lu CS, Fisker-Andersen J, Jolley L, Fenske RA. Temporal association of children's pesticide exposure and agricultural spraying: Report of a longitudinal biological monitoring study. Environmental Health Perspectives 2002;110(8):829-833. R825171 (2000)
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    Journal Article Evaluation of the equilibrium, dynamic, and hybrid aerosol modeling approaches AEROSOL SCIENCE AND TECHNOLOGY Koo B, Gaydos TM, Pandis SN Koo B, Gaydos TM, Pandis SN. Evaluation of the equilibrium, dynamic, and hybrid aerosol modeling approaches. Aerosol Science And Technology. 2003;37:53-64. R826371 (Final)
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    Journal Article CREB transcriptional activity in neurons is regulated by multiple, calcium-specific phosphorylation events. NUERON Kornhauser JM, Cowan CW, Shaywitz AJ, Dolmetsch R, Griffith E, Hu L, Haddad C, Xia Z, Greenberg M Kornhauser JM, Cowan CW, Shaywitz AJ, Dolmetsch R, Griffith E, Hu L, Haddad C, Xia Z, Greenberg M. CREB transcriptional activity in neurons is regulated by multiple, calcium-specific phosphorylation events.Nueron2002; 34: 221-233. R831709 (2005)
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    Journal Article Report: Community-based participatory research flags environmental health hazards and fuels education and action. SCIENCE COMMUNICATION Latowsky G Latowsky G. Report: Community-based, participatory research in Lawrence, Massachusetts, flags environmental health hazards and fuels education and action. Science Communication 2003;25(2):204-208. R831709 (2006)
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  • Journal Article Methylmercury distribution in the pregnant rat and embryo during early midbrain organogenesis. TERATOLOGY Lewandowski TA, Pierce CH, Pingree SD, Hong S, Faustman EM Lewandowski TA, Pierce CH, Pingree SD, Hong S, Faustman EM. Methylmercury distribution in the pregnant rat and embryo during early midbrain organogenesis.Teratology2002; 66(5): 235-41. R831709 (2005)
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    Journal Article Changes in cell cycle parameters and cell number in the rat midbrain during organogenesis. DEVELOPMENTAL BRAIN RESEARCH Lewandowski TA, Ponce RA, Charleston JS, Hong S, Faustman EM Lewandowski TA, Ponce RA, Charleston JS, Hong S, Faustman EM. Changes in cell cycle parameters and cell number in the rat midbrain during organogenesis. Developmental Brain Research 2003;141(1-2):117-128. R831709 (2005)
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    Journal Article Effect of methylmercury on midbrain cell proliferation during organogenesis: potential cross-species differences and implications for risk assessment. TOXICOLOGICAL SCIENCES Lewandowski TA, Ponce RA, Charleston JS, Hong S, Faustman EM Lewandowski TA, Ponce RA, Charleston JS, Hong S, Faustman EM. Effect of methylmercury on midbrain cell proliferation during organogenesis: potential cross-species differences and implications for risk assessment. Toxicological Sciences 2003;75(1):124-133. R831709 (2005)
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    Journal Article Catalytic efficiency determines the in- vivo efficacy of PON1 for detoxifying organophosphorus compounds. PHARMACOGENETICS Li WF, Costa LG, Richter RJ, Hagen T, Shih DM, Tward A, Lusis AJ, Furlong CE Li WF, Costa LG, Richter RJ, Hagen T, Shih DM, Tward A, Lusis AJ, Furlong CE. Catalytic efficiency determines the in- vivo efficacy of PON1 for detoxifying organophosphorus compounds. Pharmacogenetics 2000;10(9):767-779. R826886C002 (2000)
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  • Journal Article Teratogen-induced activation of caspase-9 and the mitochondrial apoptotic pathway in early postimplantation mouse embryos. TOXICOLOGY AND APPLIED PHARMACOLOGY Little SA, Mirkes PE Little SA, Mirkes PE. Teratogen-induced activation of caspase-9 and the mitochondrial apoptotic pathway in early postimplantation mouse embryos. Toxicology and Applied Pharmacology2002; 181(2): 142-51. R831709 (2005)
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    Journal Article Biological monitoring survey of organophosphorus pesticide exposure among preschool children in the Seattle metropolitan area ENVIRONMENTAL HEALTH PERSPECTIVES Lu CS, Knutson DE, Fisker-Andersen J, Fenske RA Lu CS, Knutson DE, Fisker-Andersen J, Fenske RA. Biological monitoring survey of organophosphorus pesticide exposure among preschool children in the Seattle metropolitan area. Environmental Health Perspectives 2001;109(3):299-303. R825171 (2000)
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    Journal Article Dermal transfer of chlorpyrifos residues from residential surfaces: comparison of hand press, hand drag, wipe, and polyurethane foam roller measurements after broadcast and aerosol pesticide applications. ENVIRONMENTAL HEALTH PERSPECTIVES Lu C, Fenske RA Lu C, Fenske RA. Dermal transfer of chlorpyrifos residues from residential surfaces: comparison of hand press, hand drag, wipe, and polyurethane foam roller measurements after broadcast and aerosol pesticide applications. Environmental Health Perspectives 1999;107(6):463-467. R826886C004 (2001)
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  • Journal Article Pesticide exposure of children in an agricultural community: evidence of household proximity to farmland and take home exposure pathways. ENVIRONMENTAL RESEARCH Lu C, Fenske RA, Simcox NJ, Kalman D Lu C, Fenske RA, Simcox NJ, Kalman D. Pesticide exposure of children in an agricultural community: evidence of household proximity to farmland and take home exposure pathways. Environmental Research 2000;84(3):290-302. R826886C004 (2001)
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  • Journal Article Localization of glutamate cysteine ligase subunit mRNA within the rat ovary and relationship to follicular apoptosis. MOLECULAR REPRODUCTION AND DEVELOPMENT Luderer U, Diaz D, Faustman EM, Kavanagh TJ Luderer U, Diaz D, Faustman EM, Kavanagh TJ. Localization of glutamate cysteine ligase subunit mRNA within the rat ovary and relationship to follicular apoptosis. Molecular Reproduction and Development2003;65(3): 254-61. R831709 (2005)
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    Journal Article p21(WAF1/CIP1) inhibits cell cycle progression but not G2/M-phase transition following methylmercury exposure. TOXICOLOGY AND APPLIED PHARMACOLOGY Mendoza MAC, Ponce RA, Ou YC, Faustman EM Mendoza MAC, Ponce RA, Ou YC, Faustman EM. p21(WAF1/CIP1) inhibits cell cycle progression but not G2/M-phase transition following methylmercury exposure. Toxicology and Applied Pharmacology2002; 178(2): 117-25. R831709 (2005)
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    Journal Article Teratogen-induced cell death in postimplantation mouse embryos: differential tissue sensitivity and hallmarks of apoptosis. CELL DEATH & DIFFERENTIATION Mirkes PE, Little SA Mirkes PE, Little SA. Teratogen-induced cell death in postimplantation mouse embryos: differential tissue sensitivity and hallmarks of apoptosis. Cell Death & Differentiation1998; 5(7): 592-600. R831709 (2005)
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    Journal Article Heat shock protein 70 (Hsp70) protects postimplantation murine embryos from the embryolethal effects of hyperthermia. DEVELOPMENT DYNAMICS Mirkes PE, Cornel LM, Wilson KL, Dilmann WH Mirkes PE, Cornel LM, Wilson KL, Dilmann WH. Heat shock protein 70 (Hsp70) protects postimplantation murine embryos from the embryolethal effects of hyperthermia. Development Dynamics1999; 214(2): 159-70. R831709 (2005)
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    Journal Article Cytochrome c release from mitochondria of early postimplantation murine embryos exposed to 4-hydroperoxycyclophosphamide, heat shock, and staurosporine. TOXICOLOGY AND APPLIED PHARMACOLOGY Mirkes PE, Little SA Mirkes PE, Little SA. Cytochrome c release from mitochondria of early postimplantation murine embryos exposed to 4-hydroperoxycyclophosphamide, heat shock, and staurosporine. Toxicology and Applied Pharmacology 2000;162(3):197-206. R826886C001 (2001)
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  • Journal Article Teratogen-induced activation of ERK, JNK, and p38 MAP kinases in early postimplantation murine embryos. TERATOLOGY Mirkes PE, Wilson KL, Cornel LM Mirkes PE, Wilson KL, Cornel LM. Teratogen-induced activation of ERK, JNK, and p38 MAP kinases in early postimplantation murine embryos. Teratology 2000;62(1):14-25. R826886C001 (2001)
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  • Journal Article 2001 Warkany lecture: to die or not to die, the role of apoptosis in normal and abnormal mammalian development. TERATOLOGY Mirkes PE Mirkes PE. 2001 Warkany lecture: to die or not to die, the role of apoptosis in normal and abnormal mammalian development. Teratology2002; 65(5): 228-39. R831709 (2005)
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    Journal Article Improved cleanup and determination of dialkyl phosphates in the urine of children exposed to organophosphorus insecticides. JOURNAL OF ANALYTICAL TOXICOLOGY Moate TF, Lu C, Fenske RA, Hahne RMA, Kalman DA Moate TF, Lu C, Fenske RA, Hahne RMA, Kalman DA. Improved cleanup and determination of dialkyl phosphates in the urine of children exposed to organophosphorus insecticides. Journal of Analytical Toxicology 1999;23(4):230-236. R825171 (1999)
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  • Journal Article Size exclusion chromatographic cleanup for GC/MS determination of organophosphorus pesticide residues in household and vehicle dust. JOURNAL OF AOAC INTERNATIONAL Moate TF, Furia M, Curl C, Muniz JF, Yu J, Fenske RA Moate TF, Furia M, Curl C, Muniz JF, Yu J, Fenske RA. Size exclusion chromatographic cleanup for GC/MS determination of organophosphorus pesticide residues in household and vehicle dust. Journal of AOAC International 2002;85(1):36-43. R826886C004 (2001)
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  • Journal Article Arsenite-induced apoptosis in cortical neurons is mediated by c-Jun N-terminal protein kinase 3 and p38 mitogen-activated protein kinase. THE JOURNAL OF NEUROSCIENCE Namgung U, Xia Z Namgung U, Xia Z. Arsenite-induced apoptosis in cortical neurons is mediated by c-Jun N-terminal protein kinase 3 and p38 mitogen-activated protein kinase. The Journal of Neuroscience2000; 20(17): 6442-6451. R831709 (2005)
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    Journal Article Arsenic induces apoptosis in rat cerebellar neurons via activation of JNK3 and p38 MAP kinases. TOXICOLOGY AND APPLIED PHARMACOLOGY Namgung U, Xia Z Namgung U, Xia Z. Arsenic induces apoptosis in rat cerebellar neurons via activation of JNK3 and p38 MAP kinases. Toxicology and Applied Pharmacology 2001;174(2):130-138. R826886C001 (2002)
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  • Journal Article Induction of the cell cycle regulatory gene, p21 (Waf1, Cip1) following methylmercury exposure in vitro and in vivo. TOXICOLOGY AND APPLIED PHARMACOLOGY Ou YC, Thompson SA, Ponce RA, Shroeder J, Kavanagh TJ, Faustman EM Ou YC, Thompson SA, Ponce RA, Shroeder J, Kavanagh TJ, Faustman EM. Induction of the cell cycle regulatory gene, p21 (Waf1, Cip1) following methylmercury exposure in vitro and in vivo. Toxicology and Applied Pharmacology 1999;157:203-212. R825358 (Final)
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    Journal Article The role of intracellular glutathione in methylmercury-induced toxicity in embryonic neuronal cells. NEUROTOXICOLOGY Ou YC, White CC, Krejsa CM, Ponce RA, Kavanagh TJ, Faustman EM Ou YC, White CC, Krejsa, CM, Ponce RA, Kavanagh TJ, Faustman EM. The role of intracellular glutathione in methylmercury-induced toxicity in embryonic neuronal cells. Neurotoxicology, Volume 20, Issue 5, October 1999, Pages 793-804. R825358 (Final)
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    Journal Article The role of glutathione in methylmercury-induced toxicity in primary rodent embryonic cells. TOXICOLOGY AND APPLIED PHARMACOLOGY Ou Y, Thompson S Ou Y, Thompson S. The role of glutathione in methylmercury-induced toxicity in primary rodent embryonic cells. Toxicology and Applied Pharmacology 1999;157(3): 203-212. R831709 (2005)
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    Journal Article Weighing the risks and the benefits: a call for the empirical assessment of perceived teratogenic risk. REPRODUCTIVE TOXICOLOGY Polifka JE, Faustman EM, Neil N Polifka JE, Faustman EM, Neil N. Weighing the risks and the benefits: a call for the empirical assessment of perceived teratogenic risk. Reproductive Toxicology1997;11(4): 633-40. R831709 (2005)
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    Journal Article Developmental toxicity: web resources for evaluating risk in humans. TOXICOLOGY Polifka JE, Faustman EM Polifka JE, Faustman EM. Developmental toxicity: web resources for evaluating risk in humans. Toxicology 2002;173:35-65. R831709 (2005)
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    Journal Article Use of quality-adjusted life year weights with dose response models for public health decisions: A case study of the risks and benefits of fish consumption. RISK ANALYSIS Ponce RA, Bartell SM, Wong EY , LaFlamme D , Carrington C , Lee RC , Patrick DL, Faustman EM, Bolger M Ponce RA, Bartell SM, Wong EY , LaFlamme D , Carrington C , Lee RC , Patrick DL, Faustman EM, Bolger M. Use of quality-adjusted life year weights with dose response models for public health decisions: A case study of the risks and benefits of fish consumption. Risk Analysis2000; 20: 529-542. R831709 (2005)
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    Journal Article Quality adjusted life years (QALYs) and dose response models in environmental health policy analysis-methodological considerations. SCIENCE OF THE TOTAL ENVIRONMENT Ponce RA, Wong EY, Faustman EM Ponce RA, Wong EY, Faustman EM. Quality adjusted life years (QALYs) and dose response models in environmental health policy analysis-methodological considerations.Science of the Total Environment2001;274(1-3): 79-91. R831709 (2005)
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    Journal Article SRF-dependent gene expression is required for PI3-kinase-regulated cell proliferation. THE EMBO JOURNAL Poser S, Impey S, Trinh K, Xia Z, Storm DR Poser S, Impey S, Trinh K, Xia Z, Storm DR. SRF-dependent gene expression is required for PI3-kinase-regulated cell proliferation.The EMBO Journal2000; 19(18): 4955-66. R831709 (2005)
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    Journal Article The Washington aerial spray drift study: assessment of off-target organophosphorus insecticide atmospheric movement by plant surface volatilization. ATMOSPHERIC ENVIRONMENT Ramaprasad J, Tsai M-Y, Elgethun K, Hebert VR, Felsot A, Yost MG, Fenske RA Ramaprasad J, Tsai M-Y, Elgethun K, Hebert VR, Felsot A, Yost MG, Fenske RA. The Washington aerial spray drift study: assessment of off-target organophosphorus insecticide atmospheric movement by plant surface volatilization. Atmospheric Environment 2004;38(33):5703-5713. R831709 (2005)
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    Journal Article Determination of paraoxonase (PON1) status requires more than genotyping. PHARMACOGENETICS Richter RJ, Furlong CE Richter RJ, Furlong CE. Determination of paraoxonase (PON1) status requires more than genotyping. Pharmacogenetics1999; 9(6): 745-53. R831709 (2005)
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    Journal Article Effects of uncertainties on exposure estimates to methylmercury: A Monte Carlo analysis of biomarkers of exposure vs. RISK ANALYSIS Sanga RN , Bartell SM, Ponce RA, Boischio A, Joiris CR, Pierce CH, Faustman EM Sanga RN , Bartell SM, Ponce RA, Boischio A, Joiris CR, Pierce CH, Faustman EM. Effects of uncertainties on exposure estimates to methylmercury: A Monte Carlo analysis of biomarkers of exposure vs. predictive dietary estimation. Risk Analysis 2001;(21): 5. R831709 (2005)
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    Journal Article Cell cycle inhibition by sodium arsenite in primary embryonic rat midbrain neuroepithelial cells. TOXICOLOGICAL SCIENCES Sidhu JS, Ponce RA, Vredevoogd MA, Yu X, Gribble E, Hong S-W, Schneider E, Faustman EM Sidhu JS, Ponce RA, Vredevoogd MA, Yu X, Gribble E, Hong S-W, Schneider E, Faustman EM. Cell cycle inhibition by sodium arsenite in primary embryonic rat midbrain neuroepithelial cells. Toxicological Sciences 2006;89(2):475-484. R831709 (2005)
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  • Journal Article Methylmercury induces differential ubiquitin conjugated protein levels in p53 variant mouse embryonal biroblasts. TOXICOLOGIST Sidhu J, Hong S Sidhu J, Hong S. Methylmercury induces differential ubiquitin conjugated protein levels in p53 variant mouse embryonal biroblasts. Toxicologist 2003;72: 323. R831709 (2005)
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    Journal Article Anthropological and psychological merge: design of a stress measure for Mexican farmworkers. CULTURE, MEDICINE AND PSYCHIATRY Snipes SA, Thompson B, O’Connor K, Godina R, Ibarra G Snipes SA, Thompson B, O’Connor K, Godina R, Ibarra G. Anthropological and psychological merge: design of a stress measure for Mexican farmworkers. Culture, Medicine and Psychiatry2007; 31(3): 359-88. R831709 (2005)
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    Journal Article Detection of the toxin domoic acid from clam extracts using a portable surface plasmon resonance biosensor. HARMFUL ALGAE Stevens RC, Soelberg SD, Eberhart BT, Spencer S, Wekell JC, Chinowsky TM, Trainer VL, Furlong CE Stevens RC, Soelberg SD, Eberhart BT, Spencer S, Wekell JC, Chinowsky TM, Trainer VL, Furlong CE. Detection of the toxin domoic acid from clam extracts using a portable surface plasmon resonance biosensor. Harmful Algae2007;6(2): 166-174. R831709 (2005)
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    Journal Article Health symptoms and exposure to organophosphate pesticides in farmworkers. AMERICAN JOURNAL OF INDUSTRIAL MEDICINE Strong LL, Thompson B, Coronado GD, Griffith WC, Vigoren EM, Islas I Strong LL, Thompson B, Coronado GD, Griffith WC, Vigoren EM, Islas I. Health symptoms and exposure to organophosphate pesticides in farmworkers. American Journal of Industrial Medecine 2004;46:599-606. R831709 (2005)
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    Journal Article Factors associated with pesticide safety practices in farmworkers. None Strong LL, Thompson B, Koepsell TD, Meischke H Strong LL, Thompson B, Koepsell TD, Meischke H. Factors associated with pesticide safety practices in farmworkers. American Journal of Industrial Medicine 2008;51(1):69-81. R831709 (2005)
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  • Journal Article L. None Strong LL, Thompson B, Koepsell TD, Meischke H Strong LL, Thompson B, Koepsell TD, Meischke H. Factors associated with pesticide safety practices in farmworkers. American Journal of Industrial Medicine 2008;51(1):69-81. R831709C003 (2007)
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  • Journal Article Asbestos and radiation as combined exposures in pulmonary fibrosis. TOXICOLOGIST Takaro T, Griffith W Takaro T, Griffith W. Asbestos and radiation as combined exposures in pulmonary fibrosis. Toxicologist 2003;72: 220. R831709 (2005)
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    Journal Article Identifying constituents to participate in a project to control pesticide exposure in children of farmworkers. ENVIRONMENTAL HEALTH PERSPECTIVES Thompson B, Coronado G, Puschel K, Allen E Thompson B, Coronado G, Puschel K, Allen E. Identifying constituents to participate in a project to control pesticide exposure in children of farmworkers. Environmental Health Perspectives 2001;109(Suppl 3):443-448. R826886C003 (2001)
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  • Journal Article Pesticide take-home pathway among children of agricultural workers: study design, methods, and baseline findings. JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE Thompson B, Coronado GD, Grossman JE, Puschel K, Solomon CC, Islas I, Curl CL, Shirai JH, Kissel JC, Fenske RA Thompson B, Coronado GD, Grossman JE, Puschel K, Solomon CC, Islas I, Curl CL, Shirai JH, Kissel JC, Fenske RA. Pesticide take-home pathway among children of agricultural workers: study design, methods, and baseline findings. Journal of Occupational and Environmental Medicine 2003;45(1):42-53. R826886C003 (2002)
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  • Journal Article Para ninos saludables: a community intervention trial to reduce organophosphate pesticide exposure in children of farmworkers None Thompson B, Coronado GD, Vigoren EM, Griffith WC, Fenske RA, Kissel JC, Shirai JH, Faustman EM Thompson B, Coronado GD, Vigoren EM, Griffith WC, Fenske RA, Kissel JC, Shirai JH, Faustman EM. Para ninos saludables: a community intervention trial to reduce organophosphate pesticide exposure in children of farmworkers.Environmental Health Perspectives 2008;116(5):687-694. R831709 (2005)
    R831709C003 (2007)
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  • Journal Article Genetic polymorphisms and mechanisms of neurotoxicity: overview. NEUROTOXICOLOGY Tiffany-Castiglioni E, Venkratraj V, Qian Y Tiffany-Castiglioni E, Venkratraj V, Qian Y. Genetic polymorphisms and mechanisms of neurotoxicity: overview. Neurotoxicology 2005;26(4):641-649. R831709C002 (2004)
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    Journal Article The Washington aerial spray drift study: modeling pesticide spray drift deposition from an aerial application. ATMOSPHERIC ENVIRONMENT Tsai M-Y, Elgethun K, Ramaprasad J, Yost MG, Felsot AS, Hebert VR, Fenske RA Tsai M-Y, Elgethun K, Ramaprasad J, Yost MG, Felsot AS, Hebert VR, Fenske RA. The Washington aerial spray drift study:modeling pesticide spray drift deposition from an aerial application. Atmospheric Environment 2005;39(33):6194-6203. R831709 (2005)
    R831709C004 (2005)
    R831709C004 (2006)
  • Full-text: ScienceDirect Full Text
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  • Journal Article Co-localization of active caspase-3 and DNA fragmentation (TUNEL) in normal and hyperthermia-induced abnormal mouse development. TERATOLOGY Umpierre CC, Little SA, Mirkes PE Umpierre CC, Little SA, Mirkes PE. Co-localization of active caspase-3 and DNA fragmentation (TUNEL) in normal and hyperthermia-induced abnormal mouse development. Teratology 2001;63(3):134-143. R826886C001 (2001)
    R826886C001 (2002)
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  • Journal Article The Washington aerial spray drift study: children's exposure to methamidophos in an agricultural community following fixed-wing aircraft applications. None Weppner S, Elgethun K, Lu C, Herbert V, Yost MG, Fenske RA Weppner S, Elgethun K, Lu C, Herbert V, Yost MG, Fenske RA. The Washington aerial spray drift study: children's exposure to methamidophos in an agricultural community following fixed-wing aircraft applications. Journal of Exposure Science and Environmental Epidemiology 2006;16(5):387-396. R831709 (2005)
    R831709 (2006)
    R831709 (2007)
    R831709C004 (2006)
    R831709C004 (2007)
  • Abstract: Nature
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  • Journal Article Adult proxy responses to a survey of children's dermal soil contact activities. JOURNAL OF EXPOSURE ANALYSIS AND ENVIRONMENTAL EPIDEMIOLOGY Wong EY, Shirai JH, Garlock TJ, Kissel JC Wong EY, Shirai JH, Garlock TJ, Kissel JC. Adult proxy responses to a survey of children's dermal soil contact activities.Journal of Exposure Analysis and Environmental Epidemiology2000; 10(6 Pt 1):509-17. R831709 (2005)
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    Journal Article Survey of selected activities relevant to exposures to soils. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY Wong EY, Shirai JH, Garlock TJ, KisselJC Wong EY, Shirai JH, Garlock TJ, Kissel JC . Survey of selected activities relevant to exposures to soils.Bulletin of Environmental Contamination and Toxicology2000; 65(4): 443-50. R831709 (2005)
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    Journal Article Examination of health toxicity data with application to benefit-cost analysis of environmental health policy. TOXICOLOGIST Wong EY, Farrow S Wong EY, Farrow S. Examination of health toxicity data with application to benefit-cost analysis of environmental health policy. Toxicologist 2002;66(1-5): 100. R831709 (2005)
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    Journal Article Comparative risk and policy analysis in environmental health. RISK ANALYSIS Wong EY, Ponce RA, Farrow S, Bartell SM, Lee RC, Faustman EM Wong EY, Ponce RA, Farrow S, Bartell SM, Lee RC, Faustman EM. Comparative risk and policy analysis in environmental health. Risk Analysis 2003;23:1337-49. R831709 (2005)
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    Journal Article Assessing the health benefits of air pollution reduction for children. ENVIRONMENTAL HEALTH PERSPECTIVES Wong EY, Gohlke J, Griffith WC, Farrow S, Faustman EM Wong EY, Gohlke J, Griffith WC, Farrow S, Faustman EM. Assessing the health benefits of air pollution reduction for children. Environmental Health Perspectives 2004;112:226-32. R831709 (2005)
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    Journal Article Association between in utero organophosphate pesticide exposure and abnormal reflexes in neonates. NEUROTOXICOLOGY Young JG, Eskenazi B, Gladstone EA, Bradman A, Pedersen L, Johnson C, Barr DB, Furlong CE, Holland NT Young JG, Eskenazi B, Gladstone EA, Bradman A, Pedersen L, Johnson C, Barr DB, Furlong CE, Holland NT. Association between in utero organophosphate pesticide exposure and abnormal reflexes in neonates. NeuroToxicology 2005;26(2):199-209. R831709 (2005)
    R831709 (2006)
    R831709C002 (2004)
    R831709C002 (2006)
    R831710 (2004)
    R831710 (2005)
  • Abstract from PubMed
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  • Journal Article Essential role of extracellular matrix (ECM) overlay in establishing the functional integrity of primary neonatal rat Sertoli cell/gonocyte co-cultures: an improved in vitro model for assessment of male reproductive toxicity. TOXICOLOGY SCIENCE Yu X, Sidhu JS, Hong S, Faustman EM Yu X, Sidhu JS, Hong S, Faustman EM. Essential role of extracellular matrix (ECM) overlay in establishing the functional integrity of primary neonatal rat Sertoli cell/gonocyte co-cultures: an improved in vitro model for assessment of male reproductive toxicity. Toxicology Science 2005;84:378-93. R831709 (2005)
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    Journal Article A system-based approach to interpret dose- and time-dependent microarray data: quantitative integration of gene ontology analysis for risk assessment. TOXICOLOGICAL SCIENCES Yu X, Griffith WC, Hanspers K, Dillman III JF, Ong H, Vredevoogd MA, Faustman EM Yu X, Griffith WC, Hanspers K, Dillman III JF, Ong H, Vredevoogd MA, Faustman EM. A system-based approach to interpret dose-and time-dependent microarray data: quantitative integration of gene ontology analysis for risk assessment. Toxicological Sciences 2006;92(2):560-577. R831709 (2005)
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    R831709C001 (2006)
    R832733 (2007)
  • Abstract from PubMed
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  • Journal Article TL1, a novel tumor necrosis factor-like cytokine, induces apoptosis in endothelial cells. JOURNAL OF BIOLOGICAL CHEMISTRY Yue TL, Ni J, Romanic AM, Gu JL, Keller P, Wang C, Kumar S, Yu GL, Hart TK, Wang X, Xia Z, DeWolf WE, Feuerstein GZ Yue TL, Ni J, Romanic AM, Gu JL, Keller P, Wang C, Kumar S, Yu GL, Hart TK, Wang X, Xia Z, DeWolf WE, Feuerstein GZ. TL1, a novel tumor necrosis factor-like cytokine, induces apoptosis in endothelial cells. Involvement of activation of stress protein kinases (stress-activated protein kinase and p38 mitogen-activated protein kinase) and caspase-3-like protease. Journal of Biological Chemistry 1999;274(3): 1479-1486. R831709 (2005)
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    Journal Article p38 Mitogen-activated protein kinase mediates hypoxic regulation of Mdm2 and p53 in neurons. JOURNAL OF BIOLOGICAL CHEMISTRY Zhu Y, Mao XO, Sun Y, Xia Z, Greenberg DA Zhu Y, Mao XO, Sun Y, Xia Z, Greenberg DA. p38 Mitogen-activated protein kinase mediates hypoxic regulation of Mdm2 and p53 in neurons.Journal of Biological Chemistry2002; 277(25):22909-22914. R831709 (2005)
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    Journal Article Paraoxonase 1 promoter and coding region polymorphisms in Parkinson’s disease. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Kelada SN, Costa-Mallen P, Checkoway H, Viernes HA, Farin FM, Smith-Weller T, Franklin GM, Costa LG, Longstreth Jr. WT, Furlong CE, Javrik GP, Swanson PD Kelada SN, Costa-Mallen P, Checkoway H, Viernes HA, Farin FM, Smith-Weller T, Franklin GM, Costa LG, Longstreth Jr. WT, Furlong CE, Javrik GP, Swanson PD. Paraoxonase 1 promoter and coding region polymorphisms in Parkinson’s disease. Journal of Neurology Neurosurgery and Psychiatry 2003;74(4):546-547. R831709 (2005)
    R831709C002 (2004)
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    Journal Article The magnitude of methylmercury-induced cytotoxicity and cell cycle arrest is p53 dependent. BIRTH DEFECTS RESEARCH PART A: CLINICAL AND MOLECULAR TERATOLOGY Gribble EJ, Hong S-W, Faustman EM Gribble EJ, Hong S-W, Faustman EM. The magnitude of methylmercury-induced cytotoxicity and cell cycle arrest is p53 dependent. Birth Defects Research Part A: Clinical and Molecular Teratology 2005;73(1):29-38. R831709 (2005)
    R831709C001 (2004)
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    Report Modulation of low-level organophosphate toxicity by human PON1, as assessed by microarray analysis. None Cole TC, Pettan-Brewer C Cole TC, Pettan-Brewer C. Modulation of low-level organophosphate toxicity by human PON1, as assessed by microarray analysis. 2006; Society of Toxicology, San Diego, CA. R831709 (2005)
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    Report Organophosphates and the Risk Cup. None Fenske R Fenske, R.Organophosphates and the Risk Cup. Agrichemical and Environmental News. 1999. R831709 (2005)
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    Report Pesticide Exposure and Children. Part 1: Why Focus on Kids? None Fenske R Fenske R. Pesticide Exposure and Children. Part 1: Why Focus on Kids? Agrichemical and Environmental News. 2000. R831709 (2005)
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    Report Pesticide Exposure and Children. Part 2: Children in Agricultural Communities None Fenske R Fenske R.Pesticide Exposure and Children. Part 2: Children in Agricultural Communities. Agrichemical and Environmental News. 2000. R831709 (2005)
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    Report The take-home pathway for agricultural pesticides: contribution of occupational factors to home contamination. None Grossman JE Grossman JE . The take-home pathway for agricultural pesticides: contribution of occupational factors to home contamination. School of Public Health and Community Medicine.2001 Seattle, WA, University of Washington. R831709 (2005)
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    Report Examination of children’s health effects for benefit cost analysis of air pollutant regulations. None Wong E, Gohlke J Wong E, Gohlke J. Examination of children’s health effects for benefit cost analysis of air pollutant regulations. New Orleans, LA, Society for Risk Analysis. 2002. R831709 (2005)
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    The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.


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