![[logo] US EPA](https://webarchive.library.unt.edu/eot2008/20081110103048im_/http://www.epa.gov/epafiles/images/logo_epaseal.gif){kind=logo}
Studies of Oxidant Mechanisms
EPA Grant Number: R827353C011Subproject: this is subproject number 011 , established and managed by the Center Director under grant R827353
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
Center: EPA Harvard Center for Ambient Particle Health Effects
Center Director: Koutrakis, Petros
Title: Studies of Oxidant Mechanisms
Investigators: Godleski, John J. , Gonzalez-Flecha, Beatriz
Institution: Harvard University
EPA Project Officer: Stacey Katz/Gail Robarge,
Project Period: June 1, 1999 through May 31, 2005 (Extended to May 31, 2006)
RFA: Airborne Particulate Matter (PM) Centers (1999)
Research Category: Particulate Matter
Description:
Objective:The objective of this research project is to confirm the role of oxidants in the inflammatory response to concentrated ambient particles (CAPs) in adult rats.
This is one of 10 projects funded by the Center. The progress for the other nine projects is reported separately (see reports for R827353C001 through R827353C010.
Publications and Presentations:Publications have been submitted on this subproject: View all 3 publications for this subproject | View all 149 publications for this center
Journal Articles:Journal Articles have been submitted on this subproject: View all 3 journal articles for this subproject | View all 148 journal articles for this center
Supplemental Keywords:exposure, health effects, susceptibility, biology, toxicology, environmental chemistry, air pollutants, air pollution, air quality, ambient air, ambient air quality, ambient particle health effects, ambient particles, animal inhalation study, exposure assessment, biological mechanism, biological response, cardiopulmonary, cardiopulmonary response, cardiovascular disease, chemical exposure, environmental health hazard, exposure and effects, health risks, human exposure, human health, human health effects, human health risk, human susceptibility, inhalation, inhalation toxicology, inhaled particles, particle exposure, particulate exposure, particulates, pulmonary, pulmonary disease, respiratory, respiratory disease. , Air, Scientific Discipline, Health, RFA, Molecular Biology/Genetics, Toxicology, Biology, Risk Assessments, Epidemiology, Environmental Engineering, Environmental Microbiology, particulate matter, Environmental Chemistry, Environmental Monitoring, tropospheric ozone, ambient measurement methods, ambient air quality, cardiovascular disease, inhalation, developmental effects, epidemelogy, animal inhalation study, respiratory disease, inhalation toxicology, ambient air, oxidant mechanisms, human health risk, genetic susceptibility, particle exposure, concentrated ambient particulates (CAPs), human health effects, particulates, respiratory, measurement methods , ambient particle health effects, air pollution, ambient air monitoring, chemical exposure, pulmonary, biological mechanism , human exposure, pulmonary disease
Progress and Final Reports:
2003 Progress Report
2004 Progress Report
Final Report
Main Center Abstract and Reports:
R827353 EPA Harvard Center for Ambient Particle Health Effects
Subprojects under this Center:
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R827353C001 Assessing Human Exposures to Particulate and Gaseous Air Pollutants
R827353C002 Quantifying Exposure Error and its Effect on Epidemiological
Studies
R827353C003 St. Louis Bus, Steubenville and Atlanta Studies
R827353C004 Examining Conditions That Predispose Towards
Acute Adverse Effects of Particulate Exposures
R827353C005 Assessing Life-Shortening Associated with Exposure to
Particulate Matter
R827353C006 Investigating Chronic Effects of Exposure to Particulate
Matter
R827353C007 Determining the Effects of Particle Characteristics on Respiratory Health of Children
R827353C008 Differentiating the Roles of Particle Size, Particle Composition,
and Gaseous Co-Pollutants on Cardiac Ischemia
R827353C009 Assessing Deposition of Ambient Particles in the Lung
R827353C010 Relating Changes in Blood Viscosity, Other Clotting Parameters,
Heart Rate, and Heart Rate Variability to Particulate and Criteria Gas Exposures
R827353C011 Studies of Oxidant Mechanisms
R827353C012 Modeling Relationships Between Mobile Source Particle Emissions and Population Exposures
R827353C013 Toxicological Evaluation of Realistic Emissions of Source Aerosols (TERESA) Study
R827353C014 Identifying the Physical and Chemical Properties of Particulate Matter Responsible for the Observed Adverse Health Effects
R827353C015 Research Coordination Core
R827353C016 Analytical and Facilities Core
R827353C017 Technology Development and Transfer Core