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2000 Progress Report: Community-Based Participatory Research Project
EPA Grant Number: R826886C003Subproject: this is subproject number 003 , established and managed by the Center Director under grant R826886
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
Center: University of Washington
Center Director: Faustman, Elaine
Title: Community-Based Participatory Research Project
Investigators: Faustman, Elaine
Institution: University of Washington
EPA Project Officer: Fields, Nigel
Project Period: August 1, 1998 through December 31, 2003
Project Period Covered by this Report: August 1, 1999 through July 31,2000
Project Amount: Refer to main center abstract for funding details.
RFA: Centers for Children's Environmental Health and Disease Prevention Research (1998)
Research Category: Health Effects , Children's Health
Description:
Objective:The overall goal of this project is to reduce pesticide exposure in children of farm workers in the Yakima Valley of Washington State by breaking the pesticide “take-home” pathway. The specific aims are to: (1) develop a culturally appropriate intervention to break the pesticide take-home pathway; (2) conduct a randomized, controlled community trial to evaluate the effectiveness of the intervention as assessed by examining, as the primary outcome, changes in the urinary organophosphate pesticide metabolites of children between the ages of 2 and 5 who reside with farm workers; and (3) assess the secondary effects of the intervention by examining changes in pesticide concentrations in house dust in the residential environments of farm workers; changes in the urinary organophosphate pesticide metabolites of farm workers; and changes in self-reported knowledge, attitudes, and practices of farm workers regarding protection from pesticide exposure for children.
Progress Summary:The Community Intervention Project (CIP) is comprised of two groups located in three different geographical areas that work together to conduct the community intervention portion of the Child Health Center (CHC). Group 1 is based at the University of Washington (UW) Pacific Northwest Agriculture Safety and Health (PNASH) Center, and Group 2 is based at the Fred Hutchinson Cancer Research Center (FHCRC) and the “field location” at Sunnyside, Washington.
Group 1—CIP at the University of Washington’s PNASH Center
In Year 1 the CIP-UW group worked with the CIP-FHCRC group to ensure that proper laboratory methods were employed in the collection of urine and dust samples from farmworkers and their homes and automobiles. Year 2 activities were devoted primarily to analysis of urine and dust samples and statistical analysis of these data. This work has resulted in a Master’s Thesis written by Cynthia Curl. Work by our group was closely coordinated with the work of the CHC Exposure Assessment Core. The major findings of this work are reported in the 2000 Annual Report of the Exposure Assessment Core (see the report for R826886, the overall Center report).
The key finding from these analyses was a determination that intervention and control communities did not differ significantly in terms of pesticide metabolite concentrations in either child or adult urine. There were also no significant differences across these two groups in pesticide concentrations in house or vehicle dust. These data also allow us to compare children’s exposure levels in the Yakima region with exposure levels of children in the Chelan-Douglas county region (a similar agricultural region north of Yakima) and to exposure levels of children in the Seattle metropolitan area. We are currently developing a lay interpretation of these data for the CIP Community Advisory Board and also plan to produce a report for risk managers that integrates the findings across the studies we have conducted in Washington state over the past 8 years.
Future Activities:Project 1—CIP at the University of Washington’s PNASH Center
In year 3, CIP-UW will complete statistical analysis of urine and dust data collected and submit several manuscripts based on these data. We will also continue our liaison efforts with the FHCRC group and assist in planning sample collection during year 4.
Journal Articles:No journal articles submitted with this report: View all 3 publications for this subproject
Supplemental Keywords:, Toxics, Geographic Area, Scientific Discipline, Health, RFA, Risk Assessments, Health Risk Assessment, Children's Health, Biochemistry, pesticides, Environmental Chemistry, State, exposure assessment, health effects, Washington (WA), intervention, environmental toxicant, assessment of exposure, farmworkers, harmful environmental agents, agricultural community, exposure pathways, pesticide exposure, biological response, children, environmental risks, environmental health hazard, pesticide residue, human exposure
Relevant Websites:
http://depts.washington.edu/chc/ 
Progress and Final Reports:
Original Abstract
2001 Progress Report
2002 Progress Report
Main Center Abstract and Reports:
R826886 University of Washington
Subprojects under this Center:
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R826886C001 Molecular Mechanisms of Pesticide-Induced Developmental Toxicity
R826886C002 Genetic Susceptibility to Pesticides (Paraoxonase Polymorphism or PON1 Study)
R826886C003 Community-Based Participatory Research Project
R826886C004 Pesticide Exposure Pathways Research Project