| Reference Type
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Citation
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Progress Report Year
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Document Sources
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| Journal Article |
Gatti D, Maki A, Chesler EJ, Kirova R, Kosyk O, Lu L, Manly KF, Williams RW, Perkins A, Langston MA, Threadgill DW, Rusyn I. Genome-level analysis of genetic regulation of liver gene expression networks. Hepatology 2007;46(2):548-557. |
R832720 (2007)
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Abstract from PubMed
Full-text: InterScience Full Text
Other: InterScience PDF
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| Journal Article |
Graham MR, Virtaneva K, Porcella SF, Gardner DJ, Long RD, Welty DM, Barry WT, Johnson CA, Parkins LD, Wright FA, Musser JM. Analysis of the transcriptome of Group A Streptococcus in mouse soft tissue infection. American Journal of Pathology 2006;169(3):927-942. |
R832720 (2007)
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Abstract from PubMed
Full-text: American Journal of Pathology Full Text
Other: American Journal of Pathology PDF
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| Journal Article |
Hu J, Wright FA, Zou F. Estimation of expression indexes for oligonucleotide arrays using the singular value decomposition. Journal of the American Statistical Association 2006;101(473):41-50. |
R832720 (2006)
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not available
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| Journal Article |
Nadler JJ, Zou F, Huang H, Moy SS, Lauder J, Crawley JN, Threadgill DW, Wright FA, Magnuson TR. Large-scale gene expression differences across brain regions and inbred strains correlates with a behavioral phenotype. Genetics 2006;174(3):1229-1236. |
R832720 (2006)
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not available
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| Journal Article |
Roberts A, Pardo-Manuel de Villena F, Wang W, McMillan L, Threadgill DW. The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics. Mammalian Genome 2007;18(6-7):473-481. |
R832720 (2007)
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Abstract from PubMed
Other: SpringerLink PDF
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| Journal Article |
Tropsha A, Golbraikh A. Predictive QSAR modeling workflow, model applicability domains, and virtual screening. Current Pharmaceutical Design 2007;13(34):3494-3504. |
R832720 (2007)
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Abstract from PubMed
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| Journal Article |
Woods CG, Vanden Heuvel JP, Rusyn I. Genomic profiling in nuclear receptor-mediated toxicity. Toxicologic Pathology 2007;35(4):474-494. |
R832720 (2007)
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Abstract from PubMed
Other: Toxicologic Pathology PDF
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| Journal Article |
Woods CG, Kosyk O, Bradford BU, Ross PK, Burns AM, Cunningham ML, Qu P, Ibrahim JG, Rusyn I. Time course investigation of PPARα-and Kupffer cell-dependent effects of WY-14,643 in mouse liver using microarray gene expression. Toxicology and Applied Pharmacology 2007;225(3):267-277. |
R832720 (2007)
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Abstract from PubMed
Full-text: Science Direct Full Text
Other: Science Direct PDF
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| Journal Article |
Wright FA, Huang H, Guan X, Gamiel K, Jeffries C, Barry WT, Pardo-Manuel de Villena F, Sullivan PF, Wilhelmsen KC, Zou F. Simulating association studies: a data-based resampling method for candidate regions or whole genome scans. Bioinformatics 2007;23(19):2581-2588. |
R832720 (2007)
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Abstract from PubMed
Full-text: Bioinformatics Full Text
Other: Bioinformatics PDF
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| Journal Article |
Zhu H, Rusyn I, Richard A, Tropsha A. The use of cell viability assay data improves the prediction accuracy of conventional quantitative structure activity relationship models of animal carcinogenicity. Environmental Health Perspectives 2008 Jan 4 [Epub ahead of print] doi:10.1289/ehp.10573. |
R832720 (2007)
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Abstract: Environmental Health Perspectives Abstract
Other: Environmental Health Perspectives PDF
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Journal Article (10)
| Presentation |
Bradford BU, Han J, Kosyk O, Shymonyak S, Winnike J, Kono H, O’Connell T, Rusyn I. Metabolomic analysis of urine and liver after chronic alcohol treatment in C57BL/6J mice. Presented at the American Association for Studies of Liver Disease Annual Meeting, Boston, MA, 2007. |
R832720 (2007)
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not available
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| Presentation |
Chang Y-L, Zou F, Wright FA. Approximate Bayesian approaches for quantitative trait loci estimation. Presented at ENAR, Atlanta, GA, 2007 (contributed presentation). |
R832720 (2007)
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not available
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| Presentation |
Chang Y-L, Zou F, Wright FA. Approximate Bayesian approaches for quantitative trait loci estimation. Presented at the UNC Biostatistics Colloquium, Department of Biostatistics, UNC, Chapel Hill, NC, 2007. |
R832720 (2007)
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not available
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| Presentation |
DeSimone MC, Harbourt D, Boysen G, Collins L, et al. Multi-strain study of trichoroethylene toxicity in mice. Presented at the Superfund Basic Research Program Annual Meeting: New Technologies to Assess Environmental Exposure, San Diego, CA, December 10-12, 2006. |
R832720 (2006)
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not available
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| Presentation |
Dix D, Martin MT, Li Z, Judson R, Houck KA. Development of EPA’s ToxCast program for prioritizing the toxicity testing of environmental chemicals. Presented at the Annual Meeting of Society for Biomolecular Sciences, Montreal, Canada, 2007. |
R832720 (2007)
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not available
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| Presentation |
Dix D, Judson R, Kavlock R, Li Z, Martin M, Richard A, Setzer W, Houck K. EPA’s ToxCast program for predicting hazard and prioritizing toxicity testing of environmental chemicals. Presented at the International Science Forum on Computational Toxicology, Research Triangle Park, NC, 2007. |
R832720 (2007)
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not available
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| Presentation |
Gatti D, Maki A, Chesler EJ, Kirova R, et al. Examination of genetic networks that regulate gene expression in liver using complex trait analysis. To be presented at the 46th Society of Toxicology Annual Meeting, Charlotte, NC, March 25-29, 2007. |
R832720 (2006)
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not available
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| Presentation |
Golbraikh A, Zhu H, Ye L, Wang-Bell M, Tang H, Tropsha A. QSAR/QSTR analysis of imbalanced datasets using k-Nearest Neighbors approach. Presented at the Fourth International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources, Moscow, Russia, 2007. |
R832720 (2007)
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not available
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| Presentation |
Han J, Harbourt D, Danell RM, Borchers CH, et al. High-throughput metabolite profiling of serum from trichloroethylene-exposed mice by direct infusion FTICR-MS. Presented at the Superfund Basic Research Program Annual Meeting: New Technologies to Assess Environmental Exposure, San Diego, CA, December 10-12, 2006. |
R832720 (2006)
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not available
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| Presentation |
Hege A, Ross P, Su S, Stylianou I, et al. Toxicogenetic dimension in studies of the mechanisms of liver injury. Presented at the U.S. Environmental Protection Agency Science Forum, Washington, DC, May 16-18, 2006. |
R832720 (2006)
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not available
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| Presentation |
Hege A, Ross P, Balletta L, Bradford B, et al. Cross-species association mapping identifies genetic risk factors for liver toxicity. To be presented at the 46th Society of Toxicology Annual Meeting, Charlotte, NC, March 25-29, 2007. |
R832720 (2006)
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not available
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| Presentation |
Hege A, Ross PK, Threadgill DW, Rusyn I. Phenotypic anchoring of gene expression data from acetaminophen hepatotoxicity studies in the mouse model of the human population reveals biomarkers of response. Presented at the Society of Toxicology Annual Meeting, Seattle, WA, 2008. |
R832720 (2007)
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not available
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| Presentation |
Kavlock RJ, Dix D, Judson R, Li Z, Martin M, Richard A, Setzer W, Houck K. U.S. EPA’s ToxCast program for predicting hazard and prioritizing toxicity testing of environmental chemicals. Presented at the 6th World Congress on Alternatives and Animal Use in the Life Sciences, Tokyo, 2007. |
R832720 (2007)
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not available
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| Presentation |
Kim S-K, DeSimone MC, Harbourt D, Boysen G, Collins L, Waidyanatha S, Bradford BU, Threadgill DW, Rusyn I. Analysis of trichloroethylene metabolism in a genetically diverse panel of mouse inbred strains. Presented at the Society of Toxicology Annual Meeting, Seattle, WA, 2008. |
R832720 (2007)
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not available
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| Presentation |
Lee K, Stotts D. Using aspects to create interconnected analysis tool networks. To be presented at the International Symposium on Bioinformatics Research and Applications, Athens, GA, May 6-8, 2008 (submitted). |
R832720 (2007)
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not available
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| Presentation |
Lee MH, Rusyn I, Threadgill DW, Marron JS. Visualization of features in curve estimates and application to genetic loci mapping. Presented at the Joint Statistical Meeting of the American Statistical Association, Seattle, WA, August 6-10, 2006. |
R832720 (2006)
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not available
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| Presentation |
Li Z, Wright FA, Royland JE. Age-dependent heterogeneity of gene expression in Fisher 344 rat retina. Presented at the 46th Annual Meeting of the Society of Toxicology, Charlotte, NC, 2007. |
R832720 (2007)
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not available
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| Presentation |
Li Z, Wright FA. Discovering relevant pathways in microarray experiments-a tutorial on honest testing methods. Presented at the EPA Info on Informatics Series, EPA RTP Facility, 2007. |
R832720 (2007)
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not available
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| Presentation |
Li Z, Wright FA, Royland JE. Significance analysis of variation change in gene expression studies. Presented at the 15th Annual International Conference on Intelligent Systems for Molecular Biology and 6th Annual European Conference on Computational Biology, Vienna, Austria, 2007. |
R832720 (2007)
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not available
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| Presentation |
Li Z, Wright FA, Elloumi F. Chemical toxicity prediction for ToxCast Phase I. To be presented at the 47th Annual Meeting of the Society of Toxicology, Seattle, WA, 2008 (accepted). |
R832720 (2007)
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not available
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| Presentation |
Liu J, Chang Y-L, Zou F, Wright FA. A fast Bayesian method for eQTL linkage analysis in experimental crosses. Presented at JSM, Salt Lake City, UT, 2007. |
R832720 (2007)
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not available
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| Presentation |
Tropsha A. Combinational QSAR modeling of chemical toxicants tested against Tetrahymena pyriformis. Presented at the Fourth International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources, Moscow, Russia, 2007. |
R832720 (2007)
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not available
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| Presentation |
Wang K, Richard A, Rusyn I, Tropsha A. Toxico-cheminformatics and QSPR modeling of the carcinogenic potency database. Presented at the 46th Society of Toxicity Annual Meeting, Charlotte, NC, March 25-29, 2007. |
R832720 (2006)
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not available
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| Presentation |
Winnike JH, Li Z, Wright FA, Macdonald JM, O’Connell TM, Watkins PB. Pharmaco-metabolomics and the prediction of hepatotoxicity. Presented to the Research Triangle Park Drug Metabolism Discussion Group, Research Triangle Park, NC, 2007. |
R832720 (2007)
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not available
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| Presentation |
Wright FA, Nobel AB, Barry WT. Hypothesis tests of functional categories in microarray data–a new approach. Presented at the UIUC Bioinformatics Seminar Series, Urbana-Champaign, IL, 2007. |
R832720 (2007)
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not available
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| Presentation |
Ye L, Zhu H, Golbraikh A, Tropsha A. Enhanced kNN-QSAR modeling of aquatic toxicity of diverse organic compounds tested by fathead minnow. Presented at the Microsoft eScience Workshop, Chapel Hill, NC, 2007. |
R832720 (2007)
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not available
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| Presentation |
Zhu H, Tropsha A, Fourches D, Varnek A, Papa E, Gramatica P, Oberg T, Dao P, Cherkasov A, Tetko IV. Combinational QSAR modeling of chemical toxicants tested against Tetrahymena pyriformis. Presented at the Microsoft eScience Workshop, Chapel Hill, NC, 2007. |
R832720 (2007)
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not available
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| Presentation |
Zhu H, Tropsha A, Fourches D, Varnek A, Papa E, Gramatica P, Oberg T, Dao P, Cherkasov A, Tetko IV. Combinational QSAR modeling of chemical toxicants tested against Tetrahymena pyriformis. Presented at the US EPA International Science Forum on Computational Toxicology, Research Triangle Park, NC, 2007. |
R832720 (2007)
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not available
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| Presentation |
Zhu H, Wang K, Rusyn I, Richard A, Tropsha A. The utilization of NTP-HTS data in predictive ADME/tox modeling. To be presented at the 46th Society of Toxicity Annual Meeting, Charlotte, NC, March 25-29, 2007. |
R832720 (2006)
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not available
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| Presentation |
Zhu H, Rusyn I, Richard A, Tropsha A. The utilization of NTP-HTS data in predictive ADME/tox modeling. Presented at the US EPA International Science Forum on Computational Toxicology, Research Triangle Park, NC, 2007. |
R832720 (2007)
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not available
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Presentation (30)
| Proceedings |
Liu J, Zhang Q, Wang W, McMillan L, Prins J. Clustering pair-wise dissimilarity data into partially ordered sets. In: Proceedings of the 12th Association for Computer Machinery Special Interest Group on Knowledge Discovery and Data Mining, International Conference on Knowledge Discovery and Data Mining, Philadelphia, PA, August 20-23, 2006:637-642. |
R832720 (2006)
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not available
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| Proceedings |
Liu J, Paulsen S, Xu X, Wang W, et al. Mining approximate frequent itemset in the presence of noise: algorithm and analysis. In: Proceedings of the Sixth Society for Industrial and Applied Mathematics Conference on Data Mining, Bethesda, MD, April 20-22, 2006:405-416. |
R832720 (2006)
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not available
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| Proceedings |
Liu J, Zhang Q, Wang W, McMillan L, Prins J. PoClustering: lossless clustering of dissimilarity data. In: Proceedings of the 2007 SIAM International Conference on Data Mining, Radisson University Hotel, Minneapolis, MN, April 26-28, 2007. |
R832720 (2007)
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not available
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| Proceedings |
Pan F, Roberts A, McMillan L, Pardo-Manuel de Villena F, Threadgill D, Wang W. Sample selection for maximal diversity. In: Proceedings of the IEEE International Conference on Data Mining, Ohama, NE, October 28-31, 2007, pp. 262-271. |
R832720 (2007)
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not available
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| Proceedings |
Roberts A, McMillan L, Wang W, Parker J, Rusyn I, Threadgill D. Inferring missing genotypes in large SNP panels using fast nearest-neighbor searches over sliding windows. In: ISMB/ECCB 2007 Conference Proceedings 21-25 July 2007, Vienna, Italy. Bioinformatics 2007;23(13):i401-i407. |
R832720 (2007)
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not available
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| Proceedings |
Wang W, Zhang X, Pan F. CARE: finding local linear correlations in high dimensional data. To appear in Proceedings of the 24th International Conference on Data Engineering, Cancun, Mexico, April 7-12, 2008. |
R832720 (2007)
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not available
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| Proceedings |
Zhang M, Wang W, Liu J. Mining approximate order preserving clusters in the presence of noise. To appear in Proceedings of the 24th International Conference on Data Engineering, Cancun, Mexico, April 7-12, 2008. |
R832720 (2007)
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not available
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| Proceedings |
Zhang X, Wang W. Mining coherent patterns from heterogeneous microarray data. In: Proceedings of the 15th Association for Computer Machinery Conference on Information and Knowledge Management, Arlington, VA, November 6-11, 2006. |
R832720 (2006)
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not available
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| Proceedings |
Zhang X, Wang W, Huan J. On demand phenotype ranking through subspace clustering. In: Proceedings of the 2007 SIAM International Conference on Data Mining, Radisson University Hotel, Minneapolis, MN, April 26-28, 2007. |
R832720 (2007)
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not available
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| Proceedings |
Zhang X, Wang W. An efficient algorithm for mining coherent patterns from heterogeneous microarrays. In: Proceedings of the 19th International Conference on Statistical and Scientific Database Management (SSDBM) 2007, Banff, Canada, July 9-11, 2007. |
R832720 (2007)
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not available
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Proceedings (10)
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