NAME: Endrin
SYNONYM(s):
1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-
1,4-endo-endo-5,8-dimethanonaphthalene; Mendrin; Nendrin;
Hexadrin
IMIS: 1017
CAS: 72-20-8
NIOSH: RTECS IO1575000; 31598
DOT: NA2761 Poison
DESCRIPTION:
Colorless to tan solid with a mild chemical odor.
MW:
381
BP:
decomposes at 245 C
VP:
2 x 10-7 mm at 25 C
INCOM:
Strong oxidizers and acids
Exposure Limits
OSHA GENERAL INDUSTRY PEL:
0.1 mg/m3 (Skin)
OSHA CONSTRUCTION INDUSTRY PEL:
0.1 mg/m3 TWA (Skin)
ACGIH TLV:
0.1 mg/m3 TWA (Skin); Appendix A4 (Not Classifiable as a Human
Carcinogen)
NIOSH REL: 0.1 mg/m3 TWA (Skin)
Health Factors
IARC:
Group 3, not classifiable as to its carcinogenicity to humans
SYMPTOM(s):
Epileptiform convulsions; stupor, headaches, dizziness; abdominal
discomfort, nausea, vomiting; insomnia; aggressive confusion,
lethargy, weakness; anorexia; In animals: liver damage
HEALTH EFFECTS:
Acute CNS Toxicity (HE4); Suspect teratogen (HE5)
LD50 (oral,rat) 7-15 mg/kg
ORGAN:
CNS, liver
Monitoring
PRIMARY SAMPLING/ANALYTICAL METHOD (SLC1):
MEDIA:
Mixed Cellulose Ester Filter (MCEF) 0.8 microns in series with Chromosorb 102 Tube (200/100 mg sections, 20/40 mesh)
ANL SOLVENT:
Toluene
MAX V:
120 Liters MAX F:
1.0 L/min
ANL 1:
Gas Chromatography; GC/ECD
REF:
1 (NIOSH S-284)
SAE:
0.12
CLASS:
Fully Validated
BULK METHOD:
Limit the amount of bulk submitted to one gram or one mL.
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