NAME: Pentachlorophenol
SYNONYM(s):
PCP
IMIS: 1989
CAS: 87-86-5
NIOSH: RTECS SM6300000; 57121
DOT: NA2020 Poison
DESCRIPTION:
Light-brown solid with a pungent odor when hot.
MW:
266
BP:
592 F
VP:
0.0002 mm
MP:
360 to 374 F
INCOM:
Strong oxidizers
Exposure Limits
OSHA GENERAL INDUSTRY PEL:
0.5 mg/m3 (Skin)
OSHA CONSTRUCTION INDUSTRY PEL:
0.5 mg/m3 TWA (Skin)
ACGIH TLV:
0.5 mg/m3 TWA (Skin); Appendix A3 (Confirmed Animal Carcinogen with
Unknown Relevance to Humans)
NIOSH REL: 0.5 mg/m3 TWA (Skin)
Health Factors
IARC:
Chlorophenols - Group 2B, possibly carcinogenic to humans
SYMPTOM(s):
Eye, nose, throat irritation; sneezing, coughing; weakness, anorexia,
low-weight; sweating; headaches; dizziness; nausea, vomiting;
dyspnea, chest pain; high fever; dermatitis
HEALTH EFFECTS:
Acute systemic toxicity (HE4); Vascular and CNS damage (HE3)
Chloracne (HE7); Suspect Teratogen (HE5)
ORGAN:
CVS, respiratory system, eyes, liver, kidneys, skin, CNS
Monitoring
PRIMARY SAMPLING/ANALYTICAL METHOD (SLC1):
MEDIA:
Two XAD-7 tubes in series
ANL SOLVENT:
Methanol
MAX V:
48 Liters MAX F:
0.2 L/min
ANL 1:
High Performance Liquid Chromatography; HPLC/UV
REF:
2 (OSHA 39)
SAE:
0.11
CLASS:
Fully Validated
NOTE:
Laboratory prepared XAD-7 sampling tube contains a glass fiber disk to trap aerosol component. OSHA personnel may obtain sampling tubes and instructions from SLTC.
COND:
Column: CN
Mobile Phase: 40:60:0.1 Acetonitrile:Water:H3PO4
Detector Wavelength: 220nm
Detection Limit: 0.007 mg/m3
WIPE:
Yes, with Glass Fiber Filter.
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