Projects

BONE HEALTH IN THE ELDERLY Appropriated (D)   Accession Number: 408148

BONE HEALTH IN THE ELDERLY Specific Cooperative Agreement (S)   Accession Number: 411620

Publications

COMMENTARY: A revised Clinician¿s Guide to the Prevention and Treatment of Osteoporosis - (Peer Reviewed Journal)

Dawson-Hughes, B. 2008. Commentary: a revised clinician¿s guide to the prevention and treatment of osteoporosis. Journal of Clinical Endocrinology and Metabolism. DOI 10.1210/jc.2008-0926.

Serum 25-hydroxyvitamin D and functional outcomes in the elderly - (Other)

Dawson-Hughes, B. 2008. Serum 25-hydroxyvitamin D and functional outcomes in the elderly. American Journal of Clinical Nutrition. 88(2)537s-540s.

Vitamin K circulating cytokines and bone mineral density in older men and women - (Peer Reviewed Journal)

Shea, K., Dallal, G., Dawson-Hughes, B., Ordovas, J.M., O'Donnell, C., Gundberg, C., Peterson, J., Booth, S.L. 2008. Vitamin K circulating cytokines and bone mineral density in older men and women. American Journal of Clinical Nutrition. 88:356-63.

Activation of the calcium sensing receptor stimulates serum gastrin and gastric acid secretion in healthy subjects - (Peer Reviewed Journal)

Ceglia, L., Harris, S., Rasmussen, H.M., Dawson-Hughes, B. 2008. Activation of the calcium sensing receptor stimulates serum gastrin and gastric acid secretion in healthy subjects . Osteoporosis International. DOI 10.1007/s00198-008-0637-8.

Activiation of the calcium sensing receptor stimulates serum gastrin and gastric acid secretion in healthy subjects - (Peer Reviewed Journal)

Ceglia, L., Harris, S.S., Rasmussen, H.M., Dawson-Hughes, B. 2008. Activiation of the calcium sensing receptor stimulates serum gastrin and gastric acid secretion in healthy subjects. Osteoporosis International. DOI 10.1007/s00198-008-0637-8.

Vitamin D3 in Fat Tissue - (Peer Reviewed Journal)

Blum, M., Dawson-Hughes, B., Dolnikowski, G., Seyoum, E., Harris, S.S. 2008. Vitamin D3 in Fat Tissue. Endocrine Journal. 33(1):90-94.

Associations between vitamin K and circulating cytokines in older men and women - (Abstract)

Shea, K.M., Dallal, G., Dawson-Hughes, B., Ordovas, J.M., O'Donnell, C.J., Gundberg, C., Peterson, J.W., Booth, S.L. 2008. Associations between vitamin K and circulating cytokines in older men and women. FASEB Journal. 22:1106.1

Vitamin D and Calcium for Fracture Prevention - (Abstract)

Dawson-Hughes, B. 2008. Vitamin D and Calcium for Fracture Prevention. Endocrine Society Meeting. Paper No. S50-3.

Effect of Vitamin K Supplementation on Bone Loss in Elderly Men and Women - (Peer Reviewed Journal)

Booth SL, Dallal G, Shea MK, Gundberg C, Peterson JW, Dawson-Hughes B. 2008. Effect of vitamin K supplementation on bone loss in elderly men and women. Journal of Clinical Endocrinology and Metabolism. 93:1217-1223.

Implications of absolute fracture risk assessment for osteoporosis practice guidelines in the U.S. - (Peer Reviewed Journal)

Dawson-Hughes, B. 2008. Implications of absolute fracture risk assessment for osteoporosis practice guidelines in the U.S. Osteoporosis International. 19(4):449-458.

Cost-Effectiveness Osteoporosis Treatment Thresholds: The United States Perspective from the National Osteoporosis Foundation Guide Committee - (Peer Reviewed Journal)

Tosteson, A., Melton, L.J., Dawson-Hughes, B., Baim, S., Favus, M.J., Khosla, S., Lindsay, R. 2008. Cost-Effectiveness Osteoporosis Treatment Thresholds: The United States Perspective from the National Osteoporosis Foundation Guide Committee. Osteoporosis International. DOI 10.1007/s00198-007-0550-6

Calcium and Vitamin D - (Book/Chapter) - (15-Dec-07)

Additive benefit of higher testosterone levels and vitamin D plus calcium supplementation in regard to fall risk reduction among older men and women - (Peer Reviewed Journal)

Bischoff-Ferrari, H.A., Orav, E.J., Dawson-Hughes, B. 2008. Additive benefit of higher testosterone levels and vitamin D plus calcium supplementation in regard to fall risk reduction among older men and women. Osteoporosis International. doi: 10.1007/s00198-08-0573-7.

Severe Vitamin D Deficiency in Swiss Hip Fracture Patients - (Peer Reviewed Journal)

Bischoff-Ferrari, H.A., Can, U., Staehelin, H., Platz, A., Dawson-Hughes, B., Henschkowski, J., Michael, B., Theiler, R. 2008. Severe Vitamin D Deficiency in Swiss Hip Fracture Patients. Bone. 42(3):597-602.

Treatment of Vitamin D deficient states - (Other)

Dawson-Hughes, B. 2007. Treatment of Vitamin D deficient states. UpToDate. Waltham, MA. Available: http://patients.uptodate.com/topic.asp?file=minmetab/11247

Alkaline diets favor lean tissue mass in older adults - (Peer Reviewed Journal)

Dawson-Hughes, B., Harris, S.S., Ceglia, L. 2008. Alkaline diets favor lean tissue mass in older adults. American Journal of Clinical Nutrition. 87(3):662-665.

Response to Teriparatide in Patients with Baseline 25-Hydroxyvitamin D Insufficiency or Sufficiency - (Peer Reviewed Journal)

Dawson-Hughes, B., Chen, P., Krege, J.H. 2007. Response to Teriparatide in Patients with Baseline 25-Hydroxyvitamin D Insufficiency or Sufficiency. Journal of Clinical Endocrinology and Metabolism. 92(12):4630-6.

Vitamin K and Vitamin D Status: Associations with Inflammatory Markers in the Framingham Offspring Study - (Peer Reviewed Journal)

Shea, K.M., Booth, S.L., Keaney, J.F., Massaro, J., D'Agostino, R.B., O'Donnell, C.J., Vasan, R.S., Kathresan, S., Benjamin, E.J., Dawson-Hughes, B. 2008. Vitamin K and Vitamin D Status: Associations with Inflammatory Markers in the Framingham Offspring Study. American Journal of Epidemiology. 167:313-320.

Body size and serum hydroxyl vitamin D response to oral supplements in healthy older adults - (Peer Reviewed Journal)

Blum, M., Dallal, G., Dawson-Hughes, B. 2008. Body size and serum hydroxyl vitamin D response to oral supplements in healthy older adults. Journal of American College of Nutrition. 27(2):274-9.

Strong Association Between Tibial Plateau Bone Mineral Density and Cartilage Damage - (Abstract)

Lo, G.H., Dumoulin-Richez, C., Nuite, M., Wheeler, L.M., Badiani, P., Joas, J., Mcadams, E.L., Dawson-Hughes, B., Caron, B., Mcalindon, T.E. 2007. Strong Association Between Tibial Plateau Bone Mineral Density and Cartilage Damage. In: American College of Rheumatology Scientific Meeting, 11/6/07-11/11/07, Boston, MA. 56(9 supplement): S125.

Low Vitamin D levels are associated with greater pain and slow walking speed in patients with knee osteoarthritis (KOA) - (Abstract)

Wang, J., Nuite, M., Wheeler, L.M., Badiani, P., Joas, J., Mcadams, E.L., Fletcher, J., Lavalley, M.P., Dawson-Hughes, B., Mcalindon, T.E. 2007. Low Vitamin D levels are associated with greater pain and slow walking speed in patients with knee osteoarthritis (KOA). In: American College of Rheumatology Scientific Meeting, 11/6/07-11/11/07, Boston, MA. 56(9supplement): S124.

Don¿t Always Believe What You Are Told: A Comparison of Self-Reported with Measured Weight and Height - (Abstract)

Nuite, M., Wang, J., Wheeler, L.M., Fletcher, J., Badiani, P., Mcadams, E.L., Joas, J., Lavalley, M.P., Dawson-Hughes, B., Mcalindon, T.E. 2007. Don¿t Always Believe What You Are Told: A Comparison of Self-Reported with Measured Weight and Height.In: American College of Rheumatology Scientific Meeting. 11/6/07-11/11/07. Bosotn, MA. 56(9 Supplement): S779.

Calcium intake and risk of hip fracture in men and women a meta-analysis of prospective cohort studies and randomized controlled trials - (Peer Reviewed Journal)

Bischoff-Ferrari, H.A., Dawson-Hughes, B., Baron, J.A., Burckhardt, P., Spiegelman, D., Specker, B., Orav, E., Wong, J.B., Staehelin, H.B., O'Rielly, E., Kiel, D., Willett, W.C. 2007. Calcium intake and risk of hip fracture in men and women a meta-analysis of prospective cohort studies and randomized controlled trials. American Journal of Clinical Nutrition. 86:1780-90.

Calcium intake and hip fracture risk in men and women: a meta-analysis of prospective cohort studies and randomized controlled trials - (Peer Reviewed Journal)

Bischoff-Ferrari, H.A., Dawson-Hughes, B., Baron, J.A., Specker, B., Orav, J.E., Wong, J.B., Staehelin, H.B., O'Reilly, E., Kiel, D.P., Willett, W.C. 2007. Calcium intake and hip fracture risk in men and women: a meta-analysis of prospective cohort studies and randomized controlled trials. American Journal of Clinical Nutrition. 86(6):1780-90.

A more alkaline diet may enhance the favorable impact of dietary protein on lean tissue mass in older adults - (Abstract)

Dawson-Hughes, B., Harris, S.S., Ceglia, L. 2007. A more alkaline diet may enhance the favorable impact of dietary protein on lean tissue mass in older adults. American Society for Bone and Mineral Research Annual Meeting, 9/16/07-9/19/07, Honolulu, Hawaii. 22(1).

Activation of the calcium sensing receptor with cinacalcet increases serum gastrin levels in healthy older subjects - (Abstract)

Ceglia, L., Harris, S.S., Rasmussen, H., Dawson-Hughes, B. 2007. Activation of the calcium sensing receptor with cinacalcet increases serum gastrin levels in healthy older subjects. In: ASBMR Annual Meeting, 9/16/2007-9/19/2007, Honolulu, Hawaii.

Sunlamp Therapy for the Treatment of Vitamin D Deficiency - (Abstract)

Weil, M., Dawson-Hughes, B. 2007. Sunlamp Therapy for the Treatment of Vitamin D Deficiency. In: The Endocrine Society's 89th Annual Meeting, June 2-5, 2007, Toronto, Canada. P3-114, pg. 527.

Reduced Sun Exposure Does Not Explain the Inverse Association of 25-Hydroxyvitamin D with Percent Body Fat in Older Adults - (Abstract)

Harris, S.S., Dawson-Hughes, B. 2007. Reduced Sun Exposure Does Not Explain the Inverse Association of 25-Hydroxyvitamin D with Percent Body Fat in Older Adults. In: The American Society for Bone and Mineral Research Annual Meeting, 9/16/07-9/19/07. Honolulu, Hawaii.

Reduced Sun Exposure Does Not Explain the Inverse Association of 25-Hydroxyvitamin D with Percent Body Fat in Older Adults - (Peer Reviewed Journal)

Harris, S.S., Dawson-Hughes, B. 2007. Reduced Sun Exposure Does Not Explain the Inverse Association of 25-Hydroxyvitamin D with Percent Body Fat in Older Adults. Journal of Clinical Endocrinology and Metabolism. doi:10.1210/jc.2007-0722.

The Effects of Calcium and Vitamin D Supplementation on Blood Glucose and Markers of Inflammation in Non-diabetic Adults. Response to Tournis and Mitrakou (Online Letter) - (Other)

Pittas, A.G., Dawson-Hughes, B. 2007. The Effects of Calcium and Vitamin D Supplementation on Blood Glucose and Markers of Inflammation in Non-diabetic Adults. Response to Tournis and Mitrakou (Online Letter). Diabetes Care. 30(7): e82.

The Role of Vitamin D and Calcium in Type 2 Diabetes. A Systematic Review and Meta-Analysis - (Peer Reviewed Journal)

Pittas, A.G., Lau, J., Hu, F., Dawson-Hughes, B. 2007. The Role of Vitamin D and Calcium in Type 2 Diabetes. A Systematic Review and Meta-Analysis. Journal of Clinical Endocrinology and Metabolism. 92:2017-2029.

Therapy of Osteoporosis with Calcium and Vitamin D - (Proceedings/Symposium)

Dawson-Hughes, B., Bischoff-Ferrari, H. 2007. Therapy of Osteoporosis with Calcium and Vitamin D. Journal of Bone and Mineral Research. 22(2):V59-V63.

Where do we stand on vitamin D? - (Review Article)

Bischoff-Ferrari, H.A., Dawson-Hughes, B. 2007. Where do we stand on vitamin D? Bone. 41(1):S13-S19.

The effects of combined vitamin D and calcium supplementation on glycemia, insulin resistance and systemic inflammation in non-diabetic adults age 65 and older - (Peer Reviewed Journal)

Pittas, A.G., Harris, S.S., Stark, P., Dawson-Hughes, B. 2007. The effects of combined vitamin D and calcium supplementation on glycemia, insulin resistance and systemic inflammation in non-diabetic adults age 65 and older. Diabetes Care. 30(4):980-6.

Comparative effects of oral aromatic and branched-chain amino acids on urine calcium and excretion - (Peer Reviewed Journal)

Dawson-Hughes, B., Harris, S.S., Rasmussen, H.M., Dallal, G.E. 2007. Comparative effects of oral aromatic and branched-chain amino acids on urine calcium and excretion. Osteoporosis International. 18: 955-961.

Editorial: The urgent need to recommend an intake of vitamin D that is effective - (Other)

Vieth, R., Bischoff-Ferrari, H., Boucher, B.J., Dawson-Hughes, B., Garland, C.F., Heaney, R.P., Holick, M.F., Hollis, B.W., Norman, A.W., Scragg, R., Whiting, S.J., Willett, W.C., Zittermann, A., Mccgrath, J.J., Lamberg-Allardt, C. 2007. Editorial: The urgent need to recommend an intake of vitamin D that is effective. American Journal of Clinical Nutrition. 85(3).649-650.

Non-compliance: the Achilles heel of anti-fracture efficacy - (Review Article)

Seeman, E., Compston, J., Adachi, J., Brandi, M.L., Cooper, C., Dawson-Hughes, B., Jonsson, B., Pols, H., Cramer, J.A. 2007. Non-compliance: the Achilles heel of anti-fracture efficacy. Osteoporosis International. 18:711-19.

Matrix Gla Protein is Associated with Risk Factors for Atherosclerosis but not with Coronary Artery Calcification - (Peer Reviewed Journal)

O'Donnell, C., Price, P.A., Shea, K.M., Gagnon, D.R., Wilson, P.W., Larson, M.G., Kiel, D.P., Hoffman, U., Ferencik, M., Clouse, M.E., Williamson, M.K., Cupples, A.L., Dawson-Hughes, B., Booth, S.L. 2006. Matrix Gla Protein is Associated with Risk Factors for Atherosclerosis but not with Coronary Artery Calcification. Arteriosclerosis Thrombosis and Vascular Biology. 26(12):2769-2774.

Bone Appetit: The Role of Food and Nutrition in Building and Maintaining Strong Bones - (Popular Publication)

Dawson-Hughes, B. 2006. Bone Appetit: The Role of Food and Nutrition in Building and Maintaining Strong Bones. Invest in your Bones: An International Osteoporosis Foundation Report. Sydney, Australia: Osteoporosis Australia.

Incidence and economic burden of osteoporotic fractures in the United States, 2005-2025 - (Peer Reviewed Journal)

Burge, R., Dawson-Hughes, B., Solomon, D.H., Wong, J.B., King, A., Tosteson, A. 2006. Incidence and economic burden of osteoporotic fractures in the United States, 2005-2025. Journal of Bone and Mineral Research. 22(3):465-475.

The effects of combined vitamin D and calcium supplementation on fasting plasma glucose in non-diabetic adults age 65 and older - (Abstract)

Pittas, A.G., Harris, S.S., Stark, P., Dawson-Hughes, B. 2006. The effects of combined vitamin D and calcium supplementation on fasting plasma glucose in non-diabetic adults age 65 and older. American Diabetes Association Meeting, 66th session, June 9-12, 2006, Washington, DC. Paper No. 327-OR.

Protein intake and calcium absorption ¿ Potential role of the calcium sensor receptor - (Book/Chapter)

Dawson-Hughes, B. 2007. Protein intake and calcium absorption ¿ Potential role of the calcium sensor receptor. In: Elsevier, B.V. International Congress Series. 1297. 217-227.

Calcium plus vitamin D and the risk of fractures - (Other)

Dawson-Hughes, B. 2006. Calcium plus vitamin D and the risk of fractures. New England Journal of Medicine. 354(21):2285-7.

Calcium and Vitamin D - (Book/Chapter)

Dawson-Hughes, B. 2006. Calcium and Vitamin D. In: Favus MJ. Book Chapter. Sixth Edition. Washington, D.C.: American Society for Bone and Mineral Research. p.257-259.

EFFECT OF VITAMIN D PLUS CALCIUM ON FALLING IN AMBULATORY OLDER MEN AND WOMEN: A 3-YEAR RANDOMIZED CONTROLLED TRIAL - (Peer Reviewed Journal)

Bischoff-Ferrari, H.A., Orav, J.E., Dawson-Hughes, B. 2006. Effect of vitamin d plus calcium on falling in ambulatory older men and women: a 3-year randomized controlled trial. Archives of Internal Medicine. 166(4):424-30.

SATO SHINES A LIGHT ON SUNSHINE - (Other)

Dawson-Hughes, B. 2005. Sato shines a light on sunshine. BoneKEy-Osteovision.2(12): 39-41.

INTRODUCTION TO THE SUPPLEMENT OF THE AMERICAN JOURNAL OF MEDICINE'S ISSUE ON "IMPROVING COMPLIANCE AND PERSISTENCE WITH OSTEOPOROSIS THERAPIES" - (Proceedings/Symposium)

Dawson-Hughes, B. 2006. Introduction to the supplement of the american journal of medicine's issue on "improving compliance and persistence with osteoporosis therapies". American Journal of Medicine. 119(4 Suppl 1):s1-s2.

VITAMIN D AND CALCIUM INTAKE IN RELATION TO TYPE 2 DIABETES IN WOMEN - (Peer Reviewed Journal)

Pittas, A.G., Dawson-Hughes, B., Li, T., Van Dam, R.M., Willett, W.C., Manson, J., Hu, F.B. 2006. Vitamin d and calcium intake in relation to type 2 diabetes in women. Diabetes Care. 29(3):650-6.

INTERLEUKIN 6-174C>G POLYMORPHISM IS ASSOCIATED WITH LOW BONE MINERAL DENSITY IN OLDER SUBJECTS CONSUMING LOW CALCIUM - (Abstract)

Shen, J., Crosier, M.D., Parnell, L.D., Shea, K., Dawson-Hughes, B., Ordovas, J.M., Booth, S.L. 2006. Interleukin 6-174c>g polymorphism is associated with low bone mineral density in older subjects consuming low calcium. Experimental Biology 2006 Annual Meeting. April 1- 5, 2006. San Francisco, CA. Abstract no. 398.1.

PLASMA VITAMIN K LEVELS ARE ASSOCIATED WITH CORONARY CALCIFICATION IN OLDER ADULTS - (Abstract)

Shea, K.M., O'Donnell, C.J., Hoffman, U., Price, P.A., Dawson-Hughes, B., Booth, S.L. 2006. Plasma vitamin k levels are associated with coronary calcification in older adults. Experimental Biology 2006 Annual Meeting. April 1-5, 2006. San Francisco, CA. Abstract no. 115.2

HOW IMPORTANT IS VITAMIN D FOR BONE HEALTH? A CLINICAL SCIENTIST'S PERSPECTIVE - (Review Article)

Dawson-Hughes, B. 2005. How important is vitamin d for bone health? a clinical scientist's perspective. Endocrine News. 30(6):10-15.

ASSOCIATION BETWEEN SERUM CONCENTRATIONS OF 25-HYDROXYVITAMIN D AND GINGIVAL INFLAMMATION - (Peer Reviewed Journal)

Dietrich, T., Nunn, M., Dawson-Hughes, B., Bischoff-Ferrari, H.A. 2005. Association between serum concentrations of 25-hydroxyvitamin d and gingival inflammation. American Journal of Clinical Nutrition. 82(3):575-80.

ESTIMATES OF OPTIMAL VITAMIN D STATUS - (Other)

Dawson-Hughes, B., Heaney, R.P., Holick, M.F., Lips, P., Meunier, P.J., Vieth, R. 2005. Estimates of optimal vitamin D status. Osteoporosis International [on-line]. Available at http://www.springerlink.com

CHILDHOOD OVERWEIGHT AND MATURATIONAL TIMING IN THE DEVELOPMENT OF ADULT OVERWEIGHT AND FATNESS: THE NEWTON GIRLS STUDY AND ITS FOLLOW-UP - (Peer Reviewed Journal)

Must, A., Naumova, E., Phillips, S., Blum, M., Dawson-Hughes, B., Rand, W. 2005. Childhood overweight and maturational timing in the development of adult overweight and fatness: the newton girls study and its follow-up. Journal of Pediatrics. 116(3):620-7.

HIGHER 25-HYDROXYVITAMIN D LEVELS ARE ASSOCIATED WITH BETTER LOWER EXTREMITY FUNCTION IN BOTH ACTIVE AND INACTIVE ADULTS 60+ YEARS OF AGE - (Peer Reviewed Journal)

Bischoff-Ferrari, H.A., Dietrich, T., Orav, J.E., Hu, F.B., Zhang, Y., Karlson, E., Dawson-Hughes, B. 2004. Higher 25-hydroxyvitamin D levels are associated with better lower extremity function in both active and inactive adults 60+ years of age. American Journal of Clinical Nutrition. 80:752-758.