Project Number: 1265-31000-098-03
Project Type: Specific Cooperative Agreement

Start Date: Aug 15, 2004
End Date: Aug 14, 2009

Objective:
Design tools to process and annotate DNA sequence data, including characterization of single nucleotide polymorphisms and to continue development of EST-PAGE.

Approach:
Software will be developed or adapted for use in annotating whole genome sequence data being generated as part of international collaborations that include ARS, including gene prediction, use of comparative mapping information, and identification of novel genetic markers and positional candidate genes. Emphasis should be given to problems specific to the bovine genome sequencing project, as BFGL is intimately involved in those efforts, although development of tools with wide utility is a priority. Tools will be developed or adopted to identify and characterize single nucleotide polymorphisms (SNP) across and within breeds or lines of a species. Development and support will continue for the EST-PAGE software suite.