Prepared for:

Agency for Healthcare Research and Quality

U.S. Department of Health and Human Services

540 Gaither Road

Rockville, MD 20850

www.ahrq.gov

Contract No. 290-02-0021

Prepared by:

University of Ottawa Evidence-based Practice Center at

The University of Ottawa, Ottawa Canada

David Moher, PhD

Director

Investigators

Alaa Rostom, MD, MSc, FRCPC

Catherine Dube, MD, MSc, FRCPC

Gabriela Lewin, MD

Alexander Tsertsvadze, MD Msc

Nicholas Barrowman, PhD

Catherine Code, MD, FRCPC

Margaret Sampson, MILS

David Moher, PhD

AHRQ Publication No. 07-0596-EF-1

March 2007

Suggested Citation: Rostom A, Dube C, Lewin G. Use of Aspirin and NSAIDs to Prevent Colorectal Cancer: An Evidence Synthesis. Prepared for the Agency for Healthcare Research and Quality by the University of Ottawa Evidence-based Practice Center at the University of Ottawa, Ottawa Canada, under Contract No. 290-02-0021. AHRQ Publication No. 07-0596-EF-1. Rockville, Maryland: Agency for Healthcare Research and Quality. March 2007.

This report is based on research conducted by the University of Ottawa Evidence-based Practice Center (EPC) under contract to the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD (Contract No. 290-02-0021). Funding was provided by the Centers for Disease Control and Prevention. The findings and conclusions in this document are those of the author(s), who are responsible for its content, and do not necessarily represent the views of AHRQ. No statement in this report should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services.

The information in this report is intended to help clinicians, employers, policymakers, and others make informed decisions about the provision of health care services. This report is intended as a reference and not as a substitute for clinical judgment.

This document is in the public domain and may be used and reprinted without permission except those copyrighted materials noted for which further reproduction is prohibited without the specific permission of copyright holders.