Table 6: Level 1 Findings: Cost and Economics of Therapeutics

CERT Population Findings
HMO Diabetic patients Increasing co-pay of more that $10 for thirty day supply for oral hypoglycemics was associated with significantly reduced use.
Duke Cardiac patients Examined economic effects of beta-blocker therapies. Found that there are no clear financial incentives for hospitals and physicians, even though social and Medicare costs decreased.
Duke Cardiac patients Study projected the economic impact of drug-eluting stents on a hospital system (Duke Medical Center) $8.1 million loss was predicted in the first year and $8.7 million loss in subsequent years
Alabama Arthritis patients Found that glucocorticoid users face non-negligible incremental health care costs compared to non-users. For an estimated one million chronic glucocorticoid users, the costs to the health care system would be over $1.2 billion annually in the U.S. alone for treatment of adverse effects attributed to glucocorticoids.
Duke Cardiac patients Study evaluated the economic effects of extending the use of clopidogrel from one month to twelve months in patients who have received a percutaneous coronary intervention. Extending therapy cost $879 and reduced the risk of myocardial infarction by 2.6%. The cost would be $15,696 per life year saved. Thus, this potential change in practice appeared economically attractive.

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