Category of Cases | Age at Screening, y | Prevalence of Undiagnosed Diabetes at Screeninga | Sensitivity of CBG Screening Testb | Specificity of CBG Screening Testb | Number Needed to Screenc | Number of Diagnostic Tests Needed, nd |
---|---|---|---|---|---|---|
Men with hypertension | 35 | 0.05302 | 0.912 | 0.961 | 20.7 | 2.8 |
45 | 0.05302 | 0.938 | 0.905 | 20.1 | 3.8 | |
55 | 0.08178 | 0.938 | 0.905 | 13.0 | 3.1 | |
65 | 0.03403 | 0.938 | 0.905 | 31.3 | 4.9 | |
75 | 0.04047 | 0.938 | 0.905 | 26.3 | 4.4 | |
Women with hypertension | 35 | 0.05302 | 0.74 | 0.973 | 25.5 | 2.7 |
45 | 0.05302 | 0.796 | 0.928 | 23.7 | 3.6 | |
55 | 0.08178 | 0.796 | 0.928 | 15.4 | 3.0 | |
65 | 0.03403 | 0.796 | 0.928 | 36.9 | 4.6 | |
75 | 0.04047 | 0.796 | 0.928 | 31.0 | 4.1 | |
Men without hypertension | 35 | 0.05534 | 0.912 | 0.961 | 19.8 | 2.7 |
45 | 0.05534 | 0.938 | 0.905 | 19.3 | 3.7 | |
55 | 0.05742 | 0.938 | 0.905 | 18.6 | 3.7 | |
65 | 0.02606 | 0.938 | 0.905 | 40.9 | 5.8 | |
75 | 0.04779 | 0.938 | 0.905 | 22.3 | 4.0 | |
Women without hypertension | 35 | 0.05534 | 0.74 | 0.973 | 24.4 | 2.6 |
45 | 0.05534 | 0.796 | 0.928 | 22.7 | 3.5 | |
55 | 0.05742 | 0.796 | 0.928 | 21.9 | 3.5 | |
65 | 0.02606 | 0.796 | 0.928 | 48.2 | 5.4 | |
75 | 0.04779 | 0.796 | 0.928 | 26.3 | 3.8 |
aData from National Health and Nutrition Examination Survey III.1
bSensitivity and specificity of CBG screen based on test results of <120 mg/dL, >8 h postprandial time, as reported in Figure 2 of Rolka 2001.22
cNumber needed to screen to identify one undiagnosed diabetes case = [(prevalence of undiagnosed diabetes)(CBG sensitivity)].1
dNumber of diagnostic tests to identify one undiagnosed diabetes case = 2(1 true positive) + (number of false positive screening results undiagnosed diabetes case per undiagnosed diabetes case) = 2 + number needed to screen (1 - diabetes prevalence) (1 - CBG test specificity).
Note: CBG = capillary blood glucose.