Imatinib Efficacy Studies

1

van Oosterom, 2001⁶

I/II

Full report

3/5

Main results

1

van Oosterom, 2002⁴⁵

III

Full report

3/5

Followup efficacy data for van Oosterom, et al. 2001

2

Demetri, 2002⁴⁶

II

Full report

5/5

Main results

2

Dagher 2002⁴³

II

Full report

5/5

FDA approval summary with review of Demetri, et al. 2002 data

2

Heinrich, 2003⁴⁷

II

Full report

6/6

followup efficacy data for Demetri, et al. 2002

3

Verweij, 2003⁴⁸

II

Full report

6/6

Main results

4

Verweij, 2004⁴⁹

III

Full report

6/6

Main results

4

Zalcberg, 2004⁵⁰

II

Abstract

Unk

Followup efficacy data for Verweij, et al. 2004

5

Casali, 2004⁵¹

II

Abstract

Unk

Early results of phase II trial

6

Blay, 2004⁵²

III

Abstract

Unk

Early results of phase III trial

7

Rankin, 2004⁵³

III

Abstract

Unk

Early results of phase III trial

7

Patel, 2003⁵⁴

III

Abstract (published 2003 abstract plus commentary)

Unk

Early results of Rankin, et al. 2004 Phase III trial

Imatinib Plus Surgery Efficacy Studies

8

Bumming, 2003⁵⁵

II

Full report

4/6

Main results

9

Rutkowski, 2003⁵⁶

Retro

Full report

1/6

Main results

10

Scaife, 2003⁵⁷

Retro

Full report

2/5

Main results

11

Wu, 2003⁵⁸

Retro

Full report

1/6

Main results

Adverse Events/harm

1

van Oosterom, 2001⁶

I/II

Full report

3/5

Adverse event data reported within main results full report

1

van Oosterom, 2002⁴⁵

III

Full report

3/5

followup adverse event data for van Oosterom, et al. 2001

2

Demetri, 2002⁴⁶

II

Full report

5/5

Adverse event data reported within main results full report

2

Dagher 2002⁴³

II

Full report

5/5

FDA approval summary with review of Demetri, et al. 2002 data

3

Verweij, 2003⁴⁸

II

Full report

6/6

Adverse event data reported within main results full report

4

Verweij, 2004⁴⁹

III

Full report

6/6

Adverse event data reported within main results full report

Predictors—tumor characteristics

1

Debiec-Rychter, 2004⁵⁹

I/II

Full report

6/6

Molecular predictors, sub-study of van Oosterom, et al. 2001

2

Frolov, 2003⁶⁰

II

Full report

1/6

Molecular predictors, sub-study of Demetri, et al. 2002

2

Heinrich, 2003⁴⁷

II

Full report

6/6

Molecular predictors, sub-study of Demetri, et al. 2002

3

Verweij, 2003⁴⁸

II

Full report

6/6

Other predictors reported within main results full report

Predictors—radiological findings

1

Stroobants, 2003⁶¹

I/II

Full report

4/6

Radiological predictors, sub-study of van Oosterom, et al. 2001

12

Antoch, 2004⁶²

Pros

Full report

5/5

Radiological predictors study

13

Gayed, 2004⁶³

Pros

Full report

1/5

Radiological predictors study

14

Di Giorgi, 2004⁶⁴

Pros

Abstract

Unk

Radiological predictors study

15

Laussau, 2004⁶⁵

Pros

Abstract

Unk

Radiological predictors study

Predictors—other clinical factors

2

Heinrich, 2003⁴⁷

II

Full report

6/6

Other predictors, sub-study of Demetri, et al. 2002

4

Verweij, 2004⁴⁹

III

Full report

6/6

Other predictors reported within main results full report