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EPC Evidence Reports


Completed Reports

Clinical

 Cancer and Blood Disorders
 Complementary and Alternative Care
 Dietary Supplements
 Ear, Nose, and Throat Conditions
 Heart and Vascular Diseases
 Infectious Diseases
 Kidney Conditions
 Lung Conditions
 Mental Health Conditions and Substance Abuse
 Metabolic, Nutritional, and Endocrine Conditions
 Musculoskeletal Disorders
 Nerve and Brain Conditions
 Obstetric and Gynecologic Conditions
 Oral and Gastrointestinal Disorders
 Pediatric Conditions
 Skin Conditions

Health Care Services

 Bioterrorism
 Financing and Economic Incentives
 Information Technology
 Quality Improvement and Patient Safety

Technical

 Methodology


Clinical

Cancer and Blood Disorders

Adnexal Mass (February 2006)
   Abstract / Evidence Report

Anemia, Managing with Epoetin and Darbepoetin (May 2006)
   Comparative Evidence Review

Breast Abnormalities, Noninvasive Diagnostic Tests (February 2006)
    Comparative Evidence Review

Breast Cancer Care in Women, Measuring Quality (September 2004)
   Abstract / Summary / Evidence Report

Breast Cancer Outcomes, Gene Expression Profiling Tests (January 2008)
   Abstract / Evidence Report

Cancer Care Quality Measures, Colorectal Cancer (May 2006)
   Abstract / Evidence Report

Cancer Care Quality Measures, Symptoms and End-of-Life (May 2006)
   Abstract / Evidence Report

Cancer Clinical Trials, Recruitment of Underrepresented Populations (June 2005)
   Abstract / Summary / Evidence Report

Cancer Control Interventions, Diffusion and Dissemination (May 2003)
   Abstract / Summary / Evidence Report

Cancer Family History, Collection and Use in Primary Care (October 2007)
   Abstract / Evidence Report

Hereditary Nonpolyposis Colorectal Cancer (May 2007)
   Abstract / Evidence Report

Hydroxyurea for the Treatment of Sickle Cell Disease (February 2008)
Abstract / Evidence Report

Immuno-Augmentation Therapy and Naltrexone for Cancer Treatment (April 2003)
   Abstract / Summary / Evidence Report

Ovarian Cancer, Genomic Tests for Detection and Management (October 2006)
   Abstract / Evidence Report

Physical Activity, General Population and Cancer Patients and Survivors (June 2004)
   Abstract / Summary / Evidence Report

Prostate Cancer, Therapies for Clinically Localized (February 2008)
   Comparative Evidence Review

Small Cell Lung Cancer, Management (July 2006)
   Abstract / Evidence Report

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Complementary and Alternative Care

Meditation Practices for Health (June 2007)
    Abstract / Evidence Report

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Dietary Supplements

Antioxidant Supplements, Cancer Prevention and Treatment (October 2003)
   Abstract / Summary / Evidence Report

Antioxidant Supplements, Cardiovascular Disease Prevention and Treatment (July 2003)
   Abstract / Summary / Evidence Report

B Vitamins and Berries and Age-Related Neurodegenerative Disorders (April 2006)
   Abstract / Evidence Report

Ephedra and Ephedrine for Weight Loss and Athletic Performance Enhancement (March 2003)
   Abstract / Summary / Evidence Report

Melatonin, Treatment of Sleep Disorders (November 2004)
   Abstract / Summary / Evidence Report

Multivitamin/Mineral Supplements, Chronic Disease Prevention (May 2006)
   Abstract / Evidence Report

Omega-3 Fatty Acids, Effects on Arrhythmogenic Mechanisms in Culture Studies (March 2004)
   Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Asthma (March 2004)
   Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Cancer (February 2005)
   Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Cardiovascular Disease (March 2004)
   Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Cardiovascular Risk Factors (March 2004)
   Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Child and Maternal Health (August 2005)
   Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Cognitive Functions (February 2005)
   Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Eye Health (July 2005)
   Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects in Type II Diabetes, Rheumatoid Arthritis, and Other Diseases (March 2004)
   Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Mental Health (July 2005)
   Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Organ Transplantation (February 2005)
   Abstract / Summary / Evidence Report

Soy, Effects on Health Outcomes (August 2005)
   Abstract / Summary / Evidence Report

Vitamin D, Effectiveness and Safety in Bone Health (August 2007)
   Abstract / Evidence Report

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Ear, Nose, and Throat Conditions

Rhinitis, Allergic, in the Working-Age Population (February 2003)
   Abstract / Summary / Evidence Report

Sinusitis, Acute Bacterial—Update (June 2005)
   Abstract / Summary / Evidence Report

Heart and Vascular Diseases

Abdominal Aortic Aneurysm, Endovascular and Open Surgical Repairs (August 2006)
   Abstract / Evidence Report

Arterial Bypass, Percutaneous Coronary Interventions and Coronary Artery Bypass Grafting (October 2007)
   Comparative Evidence Review

Carbohydrate and Lipid Disorders in Persons with Spinal Cord Injury (January 2008)
   Abstract / Evidence Report

Coronary Heart Disease in Women, Selected Topics (May 2003)
   Abstract / Summary / Evidence Report

Coronary Heart Disease in Women, Systematic Review (May 2003)
   Abstract / Summary / Evidence Report

Deep Venous Thrombosis and Pulmonary Embolism (January 2003)
   Abstract / Summary / Evidence Report

Heart Failure, Cardiac Resynchronization Therapy (November 2004)
   Abstract / Summary / Evidence Report

Heart Failure Diagnosis and Prognosis, Testing for BNP and NT-proBNP (September 2006)
   Abstract / Evidence Report

Heart Failure and Left Ventricular Systolic Dysfunction, Pharmacologic Management (July 2003)
   Abstract / Summary / Evidence Report

Hypertension, Treatment with Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin II Receptor Antagonists (ARBs) (November 2007)
   Comparative Evidence Review

Left Ventricular Systolic Dysfunction, Cardiac Resynchronization Therapy & Implantable Cardiac Defibrillators (June 2007)
   Abstract / Evidence Report

Physical Activity, General Population and Cancer Patients and Survivors (June 2004)
   Abstract / Summary / Evidence Report

Post-Myocardial Infarction Depression (May 2005)
   Abstract / Summary / Evidence Report

Renal Artery Stenosis, Management Strategies (October 2006)
   Comparative Evidence Review

Renal Artery Stenosis, Management Strategies (2007 Update)
   Comparative Evidence Review

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Infectious Diseases

Antiretroviral (ARV) Drug Resistance in the Developing World (September 2007)
   Abstract / Evidence Report

Hepatitis B (October 2008)
   Abstract

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Kidney Conditions

Fecal and Urinary Incontinence in Adults, Prevention (December 2007)
   Abstract / Evidence Report

Solid Organ Transplant, Monitoring Mycophenolic Acid (February 2008)
   Abstract / Evidence Report

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Lung Conditions

Asthma, Work-Related (October 2005)
   Abstract / Summary / Evidence Report

Chronic Obstructive Pulmonary Disease, Spirometry (August 2005)
   Abstract / Summary / Evidence Report

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Mental Health Conditions and Substance Abuse

Adult Depression, Treatment with Second-Generation Antidepressants (January 2007)
   Comparative Evidence Review

Adults with Non-Psychotic Depression Treated with SSRIs, CYP450 Testing (January 2007)
   Abstract / Evidence Report

Atypical Antipsychotics, Off-Label Use (January 2007)
   
Comparative Evidence Review

Attention-Deficit/Hyperactivity Disorder, Diagnosis (October 1999)
   Clinical Focus / Summary

Alcohol Dependence, Pharmacotherapy (January 1999)
   Abstract / Summary / Evidence Report / Selected Publications

Depression, Perinatal (February 2005)
   Abstract / Summary / Evidence Report

Depression, Post-Myocardial Infarction (May 2005)
   Abstract / Summary / Evidence Report

Eating Disorders, Management (April 2006)
   Abstract / Evidence Report

Mental Health & Substance Abuse (October 2008)
   Abstract

Tobacco Use: Prevention, Cessation, and Control (June 2006)
   Abstract / Evidence Report

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Metabolic, Nutritional, and Endocrine Conditions

Diabetes Education for Children (April 2008)
   Abstract / Evidence Report

Diabetes Mellitus, Islet Transplantation in Patients (July 2004)
   Abstract / Summary / Evidence Report

Diabetes Mellitus, Use of Glycated Hemoglobin and Microalbuminuria (July 2003)
   Abstract / Summary / Evidence Report

Diabetes, Oral Medications ((July 2007)
   Comparative Evidence Review

Gestational Diabetes (March 2008)
   Abstract / Evidence Report

Impaired Glucose Tolerance and Fasting Glucose, Diagnosis, Prognosis, and Therapy (September 2005)
   Abstract / Summary/ Evidence Report

Obesity, Pharmacological and Surgical Treatment (July 2004)
   Abstract / Summary / Evidence Report / Clinician's Aid

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Musculoskeletal Disorders

Osteoarthritis, Treatment and Safety of Analgesics (September 2006)
   Comparative Evidence Review

Osteoarthritis of the Knee (October 2007)
   Abstract / Evidence Report

Osteoporosis, Treatments to Prevent Fractures (December 2007)
   Comparative Evidence Review

Rheumatoid and Psoriatic Arthritis, Drug Therapy (November 2007)
   Comparative Evidence Review

Total Knee Replacement (December 2003)
   Abstract / Summary / Evidence Report

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Nerve and Brain Conditions

Age-Related Neurodegenerative Disorders, B Vitamins and Berries (April 2006)
   Abstract / Evidence Report

Dementia, Pharmacological Treatment (April 2004)
   Abstract / Summary / Evidence Report

Headache, Treatment (February 1999)
   Overview

Hyperbaric Oxygen Therapy (September 2003)
   Abstract / Summary / Evidence Report

Insomnia, Manifestations and Management (June 2005)
   Abstract / Summary / Evidence Report

Multiple Sclerosis, Criteria to Determine Disability (May 2004)
   Abstract / Summary / Evidence Report

Spinal Cord Injury, Sexuality and Reproductive Health (December 2004)
   Abstract / Summary / Evidence Report

Stroke, Evaluation and Treatment (July 2005)
   Abstract / Summary / Evidence Report

Treatment-Resistant Epilepsy (April 2003)
   Abstract / Summary / Evidence Report

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Obstetric and Gynecologic Conditions

Adnexal Mass (February 2006)
   Abstract / Evidence Report

Breastfeeding, Maternal and Infant Health Outcomes (April 2007)
   Abstract / Evidence Report

Cesarean Delivery on Maternal Request (March 2006)
   Abstract / Evidence Report

Effectiveness of Assisted Reproductive Technology (May 2008)
   Abstract / Evidence Report

Episiotomy Use in Obstetrical Care (May 2005)
   Abstract / Summary/ Evidence Report

Maternal Weight Gain, Outcomes (May 2008)
   Abstract / Evidence Report

Menopause-Related Symptoms, Management (March 2005)
   Abstract / Summary / Evidence Report

Ovarian Cancer, Genomic Tests for Detection and Management (October 2006)
   Abstract / Evidence Report

Perinatal Depression: Prevalence and Screening (February 2005)
   Abstract / Summary / Evidence Report

Uterine Fibroids—Update (July 2007)
   Abstract / Evidence Report
Original Evidence Report: Volume I, Volume II (January 2001)

Vaginal Birth After Cesarean (March 2003)
   Abstract / Summary / Evidence Report

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Oral and Gastrointestinal Disorders

Celiac Disease (June 2004)
   Abstract / Summary / Evidence Report

Gastroesophageal Reflux Disease, Management Strategies (December 2005)
  Comparative Effectiveness Review

Periodontitis, Scaling and Root Planing Therapy (January 2004)
   Abstract / Summary / Evidence Report

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Pediatric Conditions

Breastfeeding, Maternal and Infant Health Outcomes (April 2007)
   Abstract / Evidence Report

Bronchiolitis in Infants and Children (January 2003)
   Abstract / Summary / Evidence Report

Failure to Thrive, Determining Disability in Infants and Children (March 2003)
   Abstract / Summary / Evidence Report

Low Birth Weight, Determining Disability in Infants and Children (March 2003)
   Abstract / Summary / Evidence Report

Pediatric Anthrax, Bioterrorism Preparedness (August 2006)
   Abstract / Evidence Report

Short Stature, Determining Disability in Infants and Children (March 2003)
   Abstract / Summary / Evidence Report

Toilet Training, Effectiveness of Different Methods (December 2006)
   Abstract / Evidence Report

Weight Reduction Programs, Children (September 2008)
   Abstract

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Skin Conditions

Heparin, Uses Treat Burn Injury (December 2006)
   Abstract / Evidence Report

Wound Healing, Laser Treatment and Vacuum-Assisted Closure (December 2004)
   Abstract / Summary / Evidence Report

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Health Care Services

Bioterrorism

Bioterrorism Preparedness, Regionalization (April 2004)
   Abstract / Summary / Evidence Report

Mass Casualty Incident, Training Hospital Staff to Respond (April 2004)
   Abstract / Summary / Evidence Report

Pediatric Anthrax, Bioterrorism Preparedness (August 2006)
   Abstract / Evidence Report

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Financing and Economic Incentives

Medicare Expenditures for Physicians' Services (October 2003)
   Clinical Focus

Preventive Care, Economic Incentives (August 2004)
   Abstract / Summary / Evidence Report

Quality-based Purchasing, Support Strategies (July 2004)
   Abstract / Summary / Technical Review

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Information Technology

Health Information Technology, Costs and Benefits (April 2006)
   Abstract / Evidence Report

Telemedicine for the Medicare Population—Update (January 2006)
   Abstract / Evidence Report
Original Evidence Report (July 2001)

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Quality Improvement and Patient Safety

Children With Special Health Care Needs, Care Coordination Strategies
   Abstract / Technical Review

Closing the Quality Gap
Vol. 1: Series Overview and Methodology (August 2004)

   Abstract / Fact Sheet / Technical Review
Vol. 2: Diabetes Mellitus (September 2004)
   Abstract / Technical Review
Vol. 3: Hypertension Care (January 2005)
   Abstract / Technical Review
Vol. 4: Antibiotic Prescribing Behavior (January 2006)
   Abstract / Technical Review
Vol. 5: Asthma Care (January 2007)
   Abstract / Technical Review
Vol. 6: Healthcare-Associated Infections (January 2007)
   Abstract / Technical Review
Vol. 7: Care Coordination (June 2007)
   Abstract / Technical Review

Continuing Medical Education, Effectiveness (February 2007)
   Abstract / Evidence Report

End-of-Life Care and Outcomes (November 2004)
   Abstract / Summary / Evidence Report

Literacy and Health Outcomes (January 2004)
   Abstract / Summary / Evidence Report

Minority Healthcare Quality, Improvement Strategies (January 2004)
   Abstract / Summary / Evidence Report

Nurse Staffing and Quality of Patient Care (March 2007)
   Abstract

Patient Safety Indicators: Hospital Data (August 2002)
   Abstract / Technical Review

Patient Safety, Effects of Working Conditions (March 2003)
   Abstract / Summary / Evidence Report

Periodic Health Evaluation, Value (April 2006)
   Abstract / Evidence Report

Refinement of the HCUP Quality Indicators (May 2001)
   Summary / Technical Review

Violence Prevention in Adolescents (October 2004)
   Abstract / Summary / Evidence Report

Technical

Methodology

Community-Based Participatory Research (August 2004)
   Abstract / Summary / Evidence Report

Current Validity of AHRQ Clinical Practice Guidelines (September 2002)
   Abstract / Technical Review

Empirical Evaluation, Association Between Methodological Shortcomings and Estimates of Adverse Events (October 2006)
   Abstract / Technical Review

Health Benefit Design, Consumer-Oriented Strategies for Improving (July 2007)
   Abstract / Technical Review

Meta-regression Approaches: What, Why, When, and How? (March 2004)
   Abstract / Technical Review

Statement of Work for Technical Analysis, Methodology (January 2006)
   Abstract / Technical Review

Systematic Reviews, Criteria for Distinguishing Effectiveness From Efficacy Trials (April 2006)
   Abstract / Technical Review

Systematic Reviews, Updating (September 2007)
   Abstract / Technical Review

AHRQ Advancing Excellence in Health Care