Table 1. Key Questions, Eligibility Criteria, and Number of Articles Meeting Criteria

Key question	Eligibility criteria	Systematic reviews and additional studies not in systematic reviews
All	Published between 1/1/94 and 9/1/02. English language. Human subjects, > 60 years. MEDLINE, PsycINFO, EMBASE, Cochrane Library.
1. Direct evidence of screening	RCT of screening. Health outcomes.	Systematic reviews: 0 Additional studies: 0
2. Prevalence of undiagnosed dementia	Systematic reviews. Cross-sectional prevalence. Community or primary care setting. Appropriate reference standard.	Systematic reviews: 0 Additional studies: 4^26;27;32;33
3. Accuracy of screening tests	Systematic reviews; prospective cohorts. Cross-sectional prevalence. Community or primary care setting. Appropriate reference standard.	Systematic reviews: 1³⁷ Additional studies: 9^{38-43;45;108;109}
4. Efficacy of pharmacologic treatment	Systematic reviews, RCTs. Mild to moderate dementia. Health outcomes.	Systematic reviews: 12^{72-75;86;87;93;110-114} Additional Studies: 19^{76-85;88-90;92;115-119}
5. Efficacy of nonpharmacologic interventions for patients Efficacy of caregiver interventions	Systematic reviews, RCTs. Mild to moderate dementia. Health outcomes. Systematic reviews, RCTs. Mild to moderate dementia. Health outcomes.	Systematic reviews: 0 Additional studies: 0 Systematic review: 1⁹⁶ Additional Studies: 6^{97;99-102;104*}
6. Efficacy of interventions for planning	Systematic reviews, RCTs. Mild to moderate dementia. Health outcomes.	Systematic reviews: 0 Additional studies: 0
7. Harms of screening	Systematic reviews, RCTs. Mild to moderate dementia. Psychological or other health outcomes.	Systematic reviews: 0 Additional studies: 0
8. Harms of treatment	Systematic reviews, RCTs. Mild to moderate dementia. Health outcomes.	Systematic reviews: 4^72-75 Additional studies: 5^76-80
Note: RCT indicates randomized, controlled trial. *Two articles were combined because they both report the results of one study.

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