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Drug Dosing Toolkit

Combivir (AZT + Epivir)

Type of Drug: Fixed-Dose Combination

Approved adult dosing

AZT 300 mg + Epivir 150 mg in a single tablet

one tablet, two times a day

  • Morning

    Combivir

    Combivir

  • Evening

    Combivir

    Combivir

My doctor's instructions

Notes on taking this medication

  • No food restrictions, can take with or without food
  • Do not take Combivir with Emtriva or Zerit
  • Persons with kidney problems may need an adjustment to their doses of the component drugs, and have to take them separately, not as a single pill

Same side effects as

AZT (Retrovir)

  • Nausea; stomach discomfort; headache
  • Symptoms of anemia (low red blood cell count): fatigue; shortness of breath
  • More rarely: muscle wasting; neutropenia (low white blood cell count)
  • Changes in body-fat distribution

Epivir

  • Side effects are rare but include headaches and general sense of feeling ill
  • Epivir is active against hepatitis B, and stopping it can cause "flare-up" of hepatitis B