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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Elizabeth Moylan
Welcome to BMC Biology published by BioMed Central
BMC Biology - the flagship biology journal of the BMC series - publishes research and methodology articles of special importance and broad interest in any area of biology and biomedical sciences. BMC Biology (ISSN 1741-7007) is covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Zoological Record, Thomson Reuters (ISI) and Google Scholar.
Featured articles
BMC Biology 2008, 6 :39
Cholesterol depletion will not help combat prion diseases because although inhibitors of cholesterol synthesis reduce the formation of disease-associated prion protein isoforms (PrPSc), polyunsaturated fatty acids that reduce cholesterol levels actually significantly increase PrPSc formation.
BMC Biology 2008, 6 :37
Erythropoietin (EPO), the blood-boosting hormone used for medical treatment and athletic doping, enhances hippocampus-dependent memory in mice by directly influencing neurons rather than as a side-effect of increased red blood cell production.
BMC Biology 2008, 6 :35
New insights into the evolution and development of organs in chordates stem from a study of developmental expression patterns of the Pax gene family that underwent multiple duplication and expansion among chordate groups.
BMC Biology 2008, 6 :34
The beta-globin gene clusters in platypus, mammals and birds are flanked by the same genes, indicating that this arrangement of genes originated before the divergence of birds and mammals.
BMC Biology 2008, 6 :33
Three-dimensional reconstructions of the internal anatomy of sea urchins using high-field magnetic resonance images provides rapid non-destructive insights into the morphology of museum specimens.
Latest articles published in BMC Biology [more info ]
Methodology article
Use of the viral 2A peptide for bicistronic expression in transgenic mice Georgios Trichas, Jo Begbie, Shankar Srinivas BMC Biology 2008, 6 :40 (15 September 2008) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cells Clive Bate, Mourad Tayebi, Luisa Diomede, Mario Salmona, Alun Williams BMC Biology 2008, 6 :39 (12 September 2008) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Viral cystatin evolution and three-dimensional structure modelling: a case of directional selection acting on a viral protein involved in a host-parasitoid interaction Celine Serbielle, Shafinaz Chowdhury, Samuel Pichon, Stephane Dupas, Jerome Lesobre, Enrico O Purisima, Jean-Michel Drezen, Elisabeth Huguet BMC Biology 2008, 6 :38 (10 September 2008) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Erythropoietin enhances hippocampal long-term potentiation and memory
Bartosz Adamcio, Derya Sargin, Alicja Stradomska, Lucian Medrihan, Christoph Gertler, Fabian Theis, Mingyue Zhang, Michael Muller, Imam Hassouna, Kathrin Hannke, Swetlana Sperling, Konstantin Radyushkin, Ahmed El-Kordi, Lizzy Schulze, Anja Ronnenberg, Fred Wolf, Nils Brose, Jeong-Seop Rhee, Weiqi Zhang, Hannelore Ehrenreich BMC Biology 2008, 6 :37 (9 September 2008) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Complex chloroplast RNA metabolism: just debugging the genetic programme?
Uwe G Maier, Andrew Bozarth, Helena T Funk, Stefan Zauner, Stefan A Rensing, Christian Schmitz-Linneweber, Thomas Borner, Michael Tillich BMC Biology 2008, 6 :36 (28 August 2008) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Evolution of developmental roles of Pax2/5/8 paralogs after independent duplication in urochordate and vertebrate lineages Susan Bassham, Cristian Ca estro, John H Postlethwait BMC Biology 2008, 6 :35 (22 August 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Platypus globin genes and flanking loci suggest a new insertional model for beta-globin evolution in birds and mammals Vidushi S Patel, Steven JB Cooper, Janine E Deakin, Bob Fulton, Tina Graves, Wesley C Warren, Richard K Wilson, Jennifer AM Graves BMC Biology 2008, 6 :34 (25 July 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Systematic comparison and reconstruction of sea urchin (Echinoidea) internal anatomy: a novel approach using magnetic resonance imaging Alexander Ziegler, Cornelius Faber, Susanne Mueller, Thomas Bartolomaeus BMC Biology 2008, 6 :33 (23 July 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
A periodic pattern generator for dental diversity Gareth J Fraser, Ryan F Bloomquist, J Todd Streelman BMC Biology 2008, 6 :32 (14 July 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Research article
A cryptic promoter in the first exon of the SPG4 gene directs the synthesis of the 60-kDa spastin isoform Giuseppe Mancuso, Elena I Rugarli BMC Biology 2008, 6 :31 (9 July 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Latest selected articles from BMC Medicine
This list contains articles from BMC Medicine that may be of interest to readers of BMC Biology
Research article
Increased deposition of C3b on red cells with low CR1 and CD55 in a malaria-endemic region of western Kenya: implications for the development of severe anemia Collins O Odhiambo, Walter Otieno, Christine Adhiambo, Michael M Odera, Jose A Stoute BMC Medicine 2008, 6 :23 (21 August 2008) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Research article
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells Joachim Silber, Daniel A Lim, Claudia Petritsch, Anders I Persson, Alika K Maunakea, Mamie Yu, Scott R Vandenberg, David G Ginzinger, C David James, Joseph F Costello, Gabriele Bergers, William A Weiss, Arturo Alvarez-Buylla, J Graeme Hodgson BMC Medicine 2008, 6 :14 (24 June 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Collagen density promotes mammary tumor initiation and progression Paolo P Provenzano, David R Inman, Kevin W Eliceiri, Justin G Knittel, Long Yan, Curtis T Rueden, John G White, Patricia J Keely BMC Medicine 2008, 6 :11 (28 April 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Research article
Methodological issues in detecting gene-gene interactions in breast cancer susceptibility: a population-based study in Ontario Laurent Briollais, Yuanyuan Wang, Isaac Rajendram, Venus Onay, Ellen Shi, Julia Knight, Hilmi Ozcelik BMC Medicine 2007, 5 :22 (7 August 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Corticortophin releasing factor 2 receptor agonist treatment significantly slows disease progression in mdx mice Richard T Hinkle, Frank R Lefever, Elizabeth T Dolan, Deborah L Reichart, Jefferey A Dietrich, Kathryn E Gropp, Robert I Thacker, Jeffrey P Demuth, Paula J Stevens, Xiaoyan A Qu, Alex R Varbanov, Feng Wang, Robert J Isfort BMC Medicine 2007, 5 :18 (12 July 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Debate
How to optimise the coverage rate of infant and adult immunisations in Europe Heinz-J Schmitt, Robert Booy, Robert Aston, Pierre Van Damme, R Fabian Schumacher, Magda Campins, Carlos Rodrigo, Terho Heikkinen, Catherine Weil-Olivier, Adam Finn, Per Olc n, David Fedson, Heikki Peltola BMC Medicine 2007, 5 :11 (29 May 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Risk factors and myocardial infarction in patients with obstructive sleep apnea: impact of 2-adrenergic receptor polymorphisms Nina K Bartels, Jan B rgel, Stefan Wieczorek, Nikolaus B chner, Christoph Hanefeld, Daniel Bulut, Andreas M gge, Lars C Rump, Bernd M Sanner, J rg T Epplen BMC Medicine 2007, 5 :1 (1 January 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Collagen reorganization at the tumor-stromal interface facilitates local invasion Paolo P Provenzano, Kevin W Eliceiri, Jay M Campbell, David R Inman, John G White, Patricia J Keely BMC Medicine 2006, 4 :38 (26 December 2006) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Research article
Grey matter changes can improve the prediction of schizophrenia in subjects at high risk Dominic E Job, Heather C Whalley, Andrew M McIntosh, David GC Owens, Eve C Johnstone, Stephen M Lawrie BMC Medicine 2006, 4 :29 (7 December 2006) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Hormone-replacement therapy influences gene expression profiles and is associated with breast-cancer prognosis: a cohort study Per Hall, Alexander Ploner, Judith Bj hle, Fei Huang, Chin-Yo Lin, Edison T Liu, Lance D Miller, Hans Nordgren, Yudi Pawitan, Peter Shaw, Lambert Skoog, Johanna Smeds, Sara Wedr n, John hd, Jonas Bergh BMC Medicine 2006, 4 :16 (30 June 2006) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]