Chemical Sampling Information
	Dimethylethylamine
Quick Links General Description Exposure Limits Health Factors Monitoring Search    [use word(s)/phrase ]   Table of Contents By Name A B C D E F G H I J K L M N O P Q R S T U V W X Y Z By CAS Number   General Description Synonyms: N,N-Dimethylethanamine; N,N-Dimethylethylamine; Ethyldimethylamine; N-Ethyldimethylamine OSHA IMIS Code Number: 0915 Chemical Abstracts Service (CAS) Registry Number: 598-56-1 Chemical Description and Physical Properties: clear liquid with a strong ammoniacal odor molecular formula: C4H11N molecular weight: 73.14 boiling point: 37°C vapor pressure: 395 mmHg @ 20°C flash point: -36°C melting point: -140°C Health Factors Potential symptoms: Irritation of eyes, skin, respiratory system; cough, respiratory distress; glaucopsia (temporary disturbance of visual clarity); watery, itchy eyes, bluish “halo” vision; eye, skin burns on direct contact with liquid; dizziness, weakness, fatigue, headache; nausea. Health Effects: Irritation-Eye, Nose, Throat, Skin---Marked (HE14) Affected organs: Eyes, skin, respiratory system Notes: OSHA does not have a PEL for dimethylethylamine. Some dimethylethylamine is excreted in the urine unchanged (mean post-shift half-life, 1.5 hours), but most is excreted as the metabolite dimethylethylamine-N-oxide (mean post-shift half-life, 2.9 hours). Urinary monitoring of exposure at the end of shift requires measurement of both the parent and N-oxide, as only the sum correlates well with airborne levels of dimethylethylamine exposure. Although dimethylethylamine can be absorbed through the skin, this is not an important route for systemic exposure compared with pulmonary absorption. Visual disturbances (except blindness from direct contact of liquid with eyes) may occur at concentrations above 5 ppm, TWA, and are reversible within three hours after the end of exposure. An 8-hr TWA exposure limit not to exceed 3 ppm has been suggested. Date Last Revised: 06/27/2006 Literature Basis: Lundh, T., Boman, A. and Åkesson. B.: Skin absorption of the industrial catalyst dimethylethylamine in vitro in guinea pig and human skin, and of gaseous dimethylethylamine in human volunteers. Int. Arch. Occup. Environ. Health 70(5): 309-313, 1997. Lundh, T., Ståhlbom, B. and Åkesson. B.: Dimethylethylamine in mould core manufacturing: exposure, metabolism and biological monitoring. Br. J. Ind. Med. 48(3): 203-207, 1991. Ståhlbom, B., Lundh, T., Floren, I. and Åkesson, B.: Visual disturbances in man as a result of experimental and occupational exposure to dimethylethylamine. Br. J. Ind. Med. 48(1): 26-29, 1991. Warren, D.W., Jr. and Selchan, D.F.: An industrial hygiene appraisal of triethylamine and dimethylethylamine exposure limits in the foundry industry. Am. Ind. Hyg. Assoc. J. 49(12): 630-634, 1988. Monitoring Methods used by OSHA Laboratory Sampling/Analytical Method: sampling media: Alumina Tube (400/200 mg sections) analytical solvent: Deionized Water (pH 7) maximum volume: 4 Liters   maximum flow rate: 0.1 L/min current analytical method: Gas Chromatography; GC/NPD method reference: OSHA Analytical Method (OSHA PV2096) method classification: Partially Validated All Trademarks are the property of their respective owners.