Chemical Sampling Information
	n-Valeraldehyde
Quick Links General Description Exposure Limits Health Factors Monitoring Search    [use word(s)/phrase] Table of Contents By Name A B C D E F G H I J K L M N O P Q R S T U V W X Y Z By CAS Number General Description Synonyms: Amyl aldehyde; Pentanal; Valeral; Valeraldehyde; Valeric aldehyde OSHA IMIS Code Number: V108 Chemical Abstracts Service (CAS) Registry Number: 110-62-3 NIOSH, Registry of Toxic Effects (RTECS) Identification Number: YV3600000 Department of Transportation Regulation Number (49 CFR 172.101) and Guide: 2058 129 [27 KB, PDF] NIOSH Pocket Guide to Chemical Hazards, n-Valeraldehyde: chemical description, physical properties, potentially hazardous incompatibilities, and more Exposure Limits American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 50 ppm, 176 mg/m3 TWA National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 50 ppm, 175 mg/m3 TWA; Appendix C - Supplementary Exposure Limits (Aldehydes) Health Factors Potential symptoms: Irritation of eyes, skin, nose, throat. Health Effects: Irritation-Eyes, Nose, Throat, Skin---Moderate (HE15) Affected organs: Eyes, skin, respiratory system Notes: OSHA does not have a PEL for n-valeraldehyde. Vapor/air mixtures of valeraldehyde may be explosive. Valeraldehyde is listed by the FDA as a synthetic flavoring substance that is permitted for direct addition to food for human consumption (21 CFR 172.515), and it occurs naturally in a wide variety of foods (e.g., alcoholic beverages, dairy products, cocoa, popcorn, potato chips). Valeraldehyde was one of several aldehydes that evoked erythema of the skin in volunteers when applied to the skin as a patch containing 25 µl of a 75% solution in water for five minutes. Date Last Revised: 03/08/2007 Literature Basis: NIOSH Pocket Guide to Chemical Hazards: n-Valeraldehyde. International Chemical Safety Cards (WHO/IPCS/ILO): Valeraldehyde. Pohanish, R.P. (editor): Valeraldehyde. In, Sittig’s Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 2307-2308. Wilkin, J.K. and Fortner, G.: Cutaneous vascular sensitivity to lower aliphatic alcohols and aldehydes in Orientals. Alcohol Clin. Exp. Res. 9(6): 522-525, 1985. Monitoring Methods used by OSHA Laboratory Sampling/Analytical Method: sampling media: Three Coated Glass Fiber Filters (Open Face) in one cassette, two back-to-back the third separated by a spacer. The filters are coated with 2,4-Dinitrophenylhydrazine (DNPH) and Phosphoric Acid. analytical solvent: Acetonitrile maximum volume: 3 Liters   maximum flow rate: 0.05 L/min current analytical method: High Performance Liquid Chromatography; HPLC/UV method reference: OSHA Analytical Method (OSHA 85) method classification: Fully Validated note: Keep samples in dark after sampling. All Trademarks are the property of their respective owners. Accessibility Assistance: Contact the OSHA Directorate of Science, Technology and Medicine at 202-693-2300 for assistance accessing PDF materials.