The Commission has administered two programs for adjudication of claims against the Government of Cuba. In its First Cuban Claims Program, completed on July 6, 1972, the Commission certified 5,911 claims to the U.S. Department of State as valid claims. In August 2006 the Commission completed the administration of a second Cuban claims program, evaluating previously unadjudicated claims of U.S. citizens or corporations against the Government of Cuba for losses of real and personal property taken after May 1, 1967. The first program was conducted under the authority of Title V of the International Claims Settlement Act of 1949, as amended (22 U.S.C. 1643 et seq.), while the second program was conducted pursuant to the Commission's authority under 22 U.S.C. 1623(a)(1)(C) to evaluate categories of claims referred to it by the Secretary of State. The second program began on August 10, 2005, and the filing deadline was February 13, 2006.

In its Second Cuban Claims Program, the Commission received a total of five claims, and certified two of those claims as valid: the Claim of STARWOOD HOTELS & RESORTS WORLDWIDE, INC., Claim No. CU-2-001, Decision No. CU-2-001, in the total principal amount of $51,128,926.95 (plus 6 percent simple annual interest); and the Claim of IRAIDA R. MENDEZ, Claim No. CU-2-002, Decision No. CU-2-004, in the principal amount of $16,000.00 (plus 6 percent simple annual interest). These will be added to the claims already certified in the previous program. Although there are no funds currently available to make payment on any American claims, the purpose of the Commission’s certifications will be to serve as a basis for future negotiation of a claims settlement with the Government of Cuba.