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Pilot Study of The Potential for Human Exposures to Pet-borne Diazinon Residues Following Lawn Applications in North Carolina
M.K. Morgan1, D.M. Stout1, and D.B. Barr2.
1 - U.S. EPA, National Exposure Research Laboratory, RTP, NC, USA
2 - National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
This study examined the potential for indoor/outdoor pet dogs to transport and translocate diazinon residues into homes and onto occupants following residential lawn applications. One primary objective was to investigate the potential exposures of children and their pet dogs to diazinon after a lawn application at their homes. Six families and their pet dogs were recruited into the study within a 50-mile radius of the Research Triangle Park area of North Carolina. Monitoring was conducted at pre-, 1, 2, 4, and 8 days post-application of a commercial formulation of diazinon by the homeowner. Environmental samples that were collected consisted of indoor air, soil, dust, and transferable residues from lawns and floors. First morning void urine samples were collected from both a child (< 14 years) and their parent. Samples taken from the dogs included fur clippings, paw wipes, and transferable residues using cotton gloves. Transferable residues were collected from dogs by a technician, stroking the dog five times (head-to-rump) each sampling day and by each child playing with their pet for 15-minutes on Day 2 post-application. All samples were analyzed for diazinon, except for urine, by GC/MS. Urine samples were analyzed for 2-isopropyl-6-methylpyrimidin- 4-ol (IMPy), the specific metabolite for diazinon, by HPLC/MS-MS. We report here the levels of diazinon measured in fur clipping, paw wipe, and transferable residue samples and urinary IMPy concentrations for children and adults.
Disclaimer: Although this work was reviewed by EPA and approved for publication, it may not necessarily reflect official Agency policy.