Practice parameter for the diagnosis and management of primary immunodeficiency (Algorithm 5)

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5b-4. Complement consumption? 5b-5. Defect in C1-C4 5b-8. Is only AH50 abnormal? 5b-6. Is only CH50 abnormal? 5a-4. Complement consumption 5a-5. Deficiency of component of classical or terminal pathway. 5a-3. Are levels/functions of more than one component affected? 5a-2. Is CH50 abnormal? 5b-7. Defect in C5-C9 5b-2. Measure CH50 and AH50 5-1. Suspected complement defect 5b-9. Deficiency of component of alternative pathway 5a-8. Not a complement deficiency 5a-7. Deficiency of component of alternative pathway. 5b-3. Are both CH50 and AH50 abnormal? 5a-6. Is AH50 abnormal? Source: Joint Council of Allergy, Asthma and Immunology. Practice parameter for the diagnosis and management of primary immunodeficiency. J Allergy Clin Immunol 2005 May;94:S1-63. All copyrights are reserved by the Joint Council of Allergy, Asthma and Immunology. Practice parameter for the diagnosis and management of primary immunodeficiency (Algorithm 5)