Expert Panel Members: Eric P. Winer, MD (Chair), Dana-Farber Cancer Institute; George P. Browman, MD, Tom Baker Cancer Centre, Calgary; Susan Braun, Susan G. Komen Breast Cancer Foundation; John Bryant, PhD, University of Pittsburgh; Harold J. Burstein, MD, PhD, Dana-Farber Cancer Institute; Rowan T. Chlebowski, MD, PhD, Harbor UCLA Medical Center; Melody A. Cobleigh, MD, Rush Presbyterian-St Luke´s Medical Center; Stephen B. Edge, MD, Roswell Park Cancer Institute; Richard D. Gelber, PhD, Dana-Farber Cancer Institute; Lori J. Goldstein, MD, Fox Chase Cancer Center; Julie Gralow, MD, Seattle Cancer Center Alliance; Clifford Hudis, MD, Memorial Sloan-Kettering Cancer Center; James N. Ingle, MD, Mayo Clinic; Amy S. Langer, Patient advocate and educator; former Executive Director, National Alliance of Breast Cancer Organizations (NABCO); Eleftherios P. Mamounas, MD, Aultman Cancer Center; Cheryl L. Perkins, MD, RPH, Susan G. Komen Breast Cancer Foundation; Judy Perotti, Research Advocacy Network; Trevor S. Powles, MD, PhD, Parkside Oncology Clinic, London; Kathleen I. Pritchard, MD, Toronto-Sunnybrook Regional Cancer Center; Timothy J. Whelan, BM, BCh, MSc, Cancer Care Ontario; Antonio C. Wolff, MD, FACP, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins