Welcome to NGC. Skip directly to: Search Box, Navigation, Content.


Brief Summary

GUIDELINE TITLE

Screening for prostate cancer in U.S. men: ACPM position statement on preventive practice.

BIBLIOGRAPHIC SOURCE(S)

GUIDELINE STATUS

This is the current release of the guideline.

This summary updates a previous version: Ferrini R, Woolf SH. American College of Preventive Medicine Practice Policy: screening for prostate cancer in American men. Am J Prev Med 1998 Jul;15(1):81-4.

BRIEF SUMMARY CONTENT

 
RECOMMENDATIONS
 EVIDENCE SUPPORTING THE RECOMMENDATIONS
 IDENTIFYING INFORMATION AND AVAILABILITY
 DISCLAIMER

 Go to the Complete Summary

RECOMMENDATIONS

MAJOR RECOMMENDATIONS

The American College of Preventive Medicine (ACPM) concludes that there is currently insufficient evidence to recommend routine population screening with digital rectal examination (DRE) or prostate-specific antigen (PSA), concurring with the Unites States Preventive Services Task Force (USPSTF) recommendation. The College is in agreement with the American College of Physicians (ACP) that men should be given information about the potential benefits and harms of screening and limits of current evidence in order to make an informed decision about screening. Discussion about screening should occur annually, during the routine periodic examination, or in response to a request by the patient. The effectiveness of prostate cancer screening is questionable in elderly men with competing co-morbidities and men with life expectancies of less than 10 years. Ultimately, a man should be allowed to make his own choice about screening, in consultation with his physician, taking into consideration personal preferences and life expectancy. If the patient prefers to defer to the clinician or is unable to make a decision regarding screening, then testing should not be offered as long as the patient understands the benefits, potential limitations, and adverse effects associated with screening. Key points that should be communicated during the patient encounter regarding prostate cancer screening are listed in the table below.

Pending resolution of ongoing controversies, screening for prostate cancer among African-American men and those with a family history of prostate cancer has the potential to detect treatable forms of disease that are more likely to occur in these groups than in the general population. While the usual age for prostate cancer screening is between 50 to 70 years in average risk men, it has been suggested that those who are at high risk may benefit from earlier screening beginning at age 45, while higher-risk men (those with two or more first-degree relatives with prostate cancer before age 65) be screened at age 40. Granted that prostate cancer is more likely to be found in high-risk men, issues pertaining to tumor grade have yet to be resolved (that is, optimal grade of tumor that a screening test should detect to confer a benefit in survival or morbidity), and there is still no evidence establishing effectiveness of screening in high-risk men. In the meantime, further studies are needed to establish the efficacy and optimal age at which prostate cancer screening should be initiated in these high-risk population groups.

Table: Benefits and Limitations of PSA Screening for Prostate Cancer: Key Points for Patient Discussion
Benefits of Screening Limitations of Screening
Early detection and treatment of potentially curable stage of prostate cancer (i.e., better chances of survival with localized disease). Survival benefit from prostate cancer screening has not been demonstrated in rigorous trials.
Reassurance of being at low risk for prostate cancer. False positive result may lead to increased anxiety and having to experience the discomfort and possible complications associated with biopsy (e.g., pain, hematospermia/hematuria, and infection).
PSA can be obtained with a simple blood test and is widely available. Prostate cancer may be slow growing and may never advance or progress to cause significant disease or death. Treatment can cause both short- and long-term side effects (e.g., pain, urinary incontinence, and impotence).
False reassurance from a normal test (false negative), leading to a delayed diagnosis of prostate cancer.

CLINICAL ALGORITHM(S)

None provided

EVIDENCE SUPPORTING THE RECOMMENDATIONS

TYPE OF EVIDENCE SUPPORTING THE RECOMMENDATIONS

The type of evidence supporting the recommendations is not specifically stated.

In general, the recommendations are based on a review of the literature prior to July 2007 and recommendations from other groups.

IDENTIFYING INFORMATION AND AVAILABILITY

BIBLIOGRAPHIC SOURCE(S)

ADAPTATION

Not applicable: The guideline was not adapted from another source.

DATE RELEASED

1998 (revised 2008 Feb)

GUIDELINE DEVELOPER(S)

American College of Preventive Medicine - Medical Specialty Society

SOURCE(S) OF FUNDING

American College of Preventive Medicine

GUIDELINE COMMITTEE

ACPM Prevention Practice Committee

COMPOSITION OF GROUP THAT AUTHORED THE GUIDELINE

Authors: Lionel S. Lim, MD, MPH, FACP; Kevin Sherin, MD, MPH, FACPM

Committee Members: Gershon H. Bergeisen, MD, MPH; Michael T. Compton, MD, MPH; V. James Guillory, DO, MPH, FACPM (Chair); Doug I. Hammer, MD, MPH, DrPH; Joylene John-Sowah, MD, MPH; Steven Jonas, MD, MPH (Consultant); Elizabeth Kann, MD, MPH; Ronit B. Katz, MD, FACPM; Robin McFee, DO, MPH, FACPM; Elaine S. Perry, MD, MS; Jennifer E. Rogers, MPH (Staff); and Michele A. Surricchio, MPH, CHES (Staff)

FINANCIAL DISCLOSURES/CONFLICTS OF INTEREST

No financial disclosures were reported by the authors of this paper.

GUIDELINE STATUS

This is the current release of the guideline.

This summary updates a previous version: Ferrini R, Woolf SH. American College of Preventive Medicine Practice Policy: screening for prostate cancer in American men. Am J Prev Med 1998 Jul;15(1):81-4.

GUIDELINE AVAILABILITY

Electronic copies: Available in Portable Document Format (PDF) from the American College of Preventive Medicine (ACPM) Web site.

An erratum to this guideline has been published and is available from the American Journal of Preventive Medicine Web site.

Print copies: Available from ACPM, 1307 New York Ave, N.W., Suite 200, Washington, DC 20005-5603.

AVAILABILITY OF COMPANION DOCUMENTS

None available

PATIENT RESOURCES

None available

NGC STATUS

This summary was completed by ECRI on September 1, 1998. The information was verified by the guideline developer on December 1, 1998. This NGC summary was updated by ECRI Institute on June 2, 2008. The updated information was verified by the guideline developer on June 23, 2008.

COPYRIGHT STATEMENT

This NGC summary is based on the original guideline, which is subject to the guideline developer's copyright restrictions.

DISCLAIMER

NGC DISCLAIMER

The National Guideline Clearinghouse™ (NGC) does not develop, produce, approve, or endorse the guidelines represented on this site.

All guidelines summarized by NGC and hosted on our site are produced under the auspices of medical specialty societies, relevant professional associations, public or private organizations, other government agencies, health care organizations or plans, and similar entities.

Guidelines represented on the NGC Web site are submitted by guideline developers, and are screened solely to determine that they meet the NGC Inclusion Criteria which may be found at http://www.guideline.gov/about/inclusion.aspx .

NGC, AHRQ, and its contractor ECRI Institute make no warranties concerning the content or clinical efficacy or effectiveness of the clinical practice guidelines and related materials represented on this site. Moreover, the views and opinions of developers or authors of guidelines represented on this site do not necessarily state or reflect those of NGC, AHRQ, or its contractor ECRI Institute, and inclusion or hosting of guidelines in NGC may not be used for advertising or commercial endorsement purposes.

Readers with questions regarding guideline content are directed to contact the guideline developer.


 

 

   
DHHS Logo