Recent Activity

Items 1 - 20 of 217
of 11Next
Emond C, Michalek JE, Birnbaum LS, DeVito MJ.
Free in PMC
Comparison of the use of a physiologically based pharmacokinetic model and a classical pharmacokinetic model for dioxin exposure assessments.
Environ Health Perspect. 2005 Dec;113(12):1666-8.
PMID: 16330344 [PubMed - indexed for MEDLINE]
Young AL, Giesy JP, Jones PD, Newton M.
Environmental fate and bioavailability of Agent Orange and its associated dioxin during the Vietnam War.
Environ Sci Pollut Res Int. 2004;11(6):359-70. Review.
PMID: 15603524 [PubMed - indexed for MEDLINE]
Aylward LL, Brunet RC, Carrier G, Hays SM, Cushing CA, Needham LL, Patterson DG Jr, Gerthoux PM, Brambilla P, Mocarelli P.
Concentration-dependent TCDD elimination kinetics in humans: toxicokinetic modeling for moderately to highly exposed adults from Seveso, Italy, and Vienna, Austria, and impact on dose estimates for the NIOSH cohort.
J Expo Anal Environ Epidemiol. 2005 Jan;15(1):51-65.
PMID: 15083163 [PubMed - indexed for MEDLINE]
Emond C, Birnbaum LS, DeVito MJ.
Free in PMC
Use of a physiologically based pharmacokinetic model for rats to study the influence of body fat mass and induction of CYP1A2 on the pharmacokinetics of TCDD.
Environ Health Perspect. 2006 Sep;114(9):1394-400.
PMID: 16966094 [PubMed - indexed for MEDLINE]
Wintermyer M, Skaidas A, Roy A, Yang YC, Georgapoulos P, Burger J, Cooper K.
The development of a physiologically-based pharmacokinetic model using the distribution of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the tissues of the eastern oyster (Crassostrea virginica).
Mar Environ Res. 2005 Aug;60(2):133-52.
PMID: 15757746 [PubMed - indexed for MEDLINE]
Emond C, Birnbaum LS, DeVito MJ.
Free Full Text
Physiologically based pharmacokinetic model for developmental exposures to TCDD in the rat.
Toxicol Sci. 2004 Jul;80(1):115-33. Epub 2004 Mar 31.
PMID: 15056810 [PubMed - indexed for MEDLINE]
Aylward LL, Brunet RC, Starr TB, Carrier G, Delzell E, Cheng H, Beall C.
Exposure reconstruction for the TCDD-exposed NIOSH cohort using a concentration- and age-dependent model of elimination.
Risk Anal. 2005 Aug;25(4):945-56.
PMID: 16268942 [PubMed - indexed for MEDLINE]
Thomaseth K, Salvan A.
Free in PMC
Estimation of occupational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin using a minimal physiologic toxicokinetic model.
Environ Health Perspect. 1998 Apr;106 Suppl 2:743-53.
PMID: 9599726 [PubMed - indexed for MEDLINE]
Wang X, Santostefano MJ, Evans MV, Richardson VM, Diliberto JJ, Birnbaum LS.
Determination of parameters responsible for pharmacokinetic behavior of TCDD in female Sprague-Dawley rats.
Toxicol Appl Pharmacol. 1997 Nov;147(1):151-68.
PMID: 9356318 [PubMed - indexed for MEDLINE]
Kim AH, Kohn MC, Portier CJ, Walker NJ.
Impact of physiologically based pharmacokinetic modeling on benchmark dose calculations for TCDD-induced biochemical responses.
Regul Toxicol Pharmacol. 2002 Dec;36(3):287-96.
PMID: 12473413 [PubMed - indexed for MEDLINE]
Michalek JE, Pirkle JL, Needham LL, Patterson DG Jr, Caudill SP, Tripathi RC, Mocarelli P.
Free Full Text
Pharmacokinetics of 2,3,7,8-tetrachlorodibenzo-p-dioxin in Seveso adults and veterans of operation Ranch Hand.
J Expo Anal Environ Epidemiol. 2002 Jan-Feb;12(1):44-53. Erratum in: J Expo Anal Environ Epidemiol 2002 Mar;12(2):165.
PMID: 11859432 [PubMed - indexed for MEDLINE]
Evans MV, Andersen ME.
Free Full Text
Sensitivity analysis of a physiological model for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): assessing the impact of specific model parameters on sequestration in liver and fat in the rat.
Toxicol Sci. 2000 Mar;54(1):71-80.
PMID: 10746933 [PubMed - indexed for MEDLINE]
Salvan A, Thomaseth K, Bortot P, Sartori N.
Use of a toxicokinetic model in the analysis of cancer mortality in relation to the estimated absorbed dose of dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin, TCDD).
Sci Total Environ. 2001 Jul 2;274(1-3):21-35.
PMID: 11453298 [PubMed - indexed for MEDLINE]
Wang X, Santostefano MJ, DeVito MJ, Birnbaum LS.
Free Full Text
Extrapolation of a PBPK model for dioxins across dosage regimen, gender, strain, and species.
Toxicol Sci. 2000 Jul;56(1):49-60.
PMID: 10869453 [PubMed - indexed for MEDLINE]
Young AL, Cecil PF Sr, Guilmartin JF Jr.
Assessing possible exposures of ground troops to Agent Orange during the Vietnam War: the use of contemporary military records.
Environ Sci Pollut Res Int. 2004;11(6):349-58.
PMID: 15603523 [PubMed - indexed for MEDLINE]
Michalek JE, Wolfe WH, Miner JC, Papa TM, Pirkle JL.
Indices of TCDD exposure and TCDD body burden in veterans of Operation Ranch Hand.
J Expo Anal Environ Epidemiol. 1995 Apr-Jun;5(2):209-23.
PMID: 7492907 [PubMed - indexed for MEDLINE]
Mills JJ, Andersen ME.
Dioxin hepatic carcinogenesis: biologically motivated modeling and risk assessment.
Toxicol Lett. 1993 May;68(1-2):177-89.
PMID: 8516763 [PubMed - indexed for MEDLINE]
Heinzl H, Mittlböck M, Edler L.
On the translation of uncertainty from toxicokinetic to toxicodynamic models--the TCDD example.
Chemosphere. 2007 Apr;67(9):S365-74. Epub 2007 Jan 16.
PMID: 17224175 [PubMed - indexed for MEDLINE]
Leung HW, Poland A, Paustenbach DJ, Murray FJ, Andersen ME.
Pharmacokinetics of [125I]-2-iodo-3,7,8-trichlorodibenzo-p-dioxin in mice: analysis with a physiological modeling approach.
Toxicol Appl Pharmacol. 1990 May;103(3):411-9.
PMID: 2339414 [PubMed - indexed for MEDLINE]
Kreuzer PE, Csanády GA, Baur C, Kessler W, Päpke O, Greim H, Filser JG.
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and congeners in infants. A toxicokinetic model of human lifetime body burden by TCDD with special emphasis on its uptake by nutrition.
Arch Toxicol. 1997;71(6):383-400.
PMID: 9195020 [PubMed - indexed for MEDLINE]
Items 1 - 20 of 217
of 11Next