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Publications

Listed below are ftp downloadable pdf publications by AM Richard and coauthors pertaining specifically to the DSSTox project or, more generally, to the status of public toxicity databases for use in structure-activity relationship modeling and the challenges of structure-based toxicity prediction. Permissions were kindly provided by a number of publishers, and are gratefully acknowledged allowing us to post published articles.

You will need Adobe Acrobat Reader, available as a free download, to view the Adobe PDF files on this page. See EPA's PDF page to learn more about PDF, and for a link to the free Acrobat Reader.

CODDD Invited Review Publication - 2006
Richard AM, Gold LS, and Nicklaus MC (2006) Chemical structure indexing of toxicity data on the Internet: Moving toward a flat world, Current Opinion in Drug Discovery & Development (CODDD), 9(3):314-325.
Reprinted in modified pdf format with kind permission of Thomson Scientific. Standard personal use copyright restrictions apply.
Download PDF (PDF, 12 pp, 672 KB)

QSAR Modelling Society Newsletter: DSSTox Update & future plans - 2004
Richard AM (2004) DSSTox update & future plans, QSAR and Modelling Society Newsletter, Issue 15, October 2004:34-36.
Download PDF (PDF, 2 pp, 87 KB)
Download PDF of full QSAR Modelling Society Newsletter Issue 15 (PDF, 56 pp, 2.2 MB)

Biotechniques:Preclinica Commentary - 2004
Richard AM (2004) DSSTox web site launch: Improving public access to databases for building structure-toxicity prediction models, Preclinica, March/April, 2(2):103-108.
Article can be accessed by signing up for a free on-line subscription to Preclinica at http://www.preclinica.com/ exit EPA

In: QSARs of Mutagens and Carcinogens, CRC Press, Ed. R. Benigni - 2003
Richard AM and Williams CR (2003) Public sources of mutagenicity and carcinogenicity data: Use in structure-activity relationship model, in QSARs of Mutagens and Carcinogens, Ed. R. Benigni, CRC Press, NY.
Reprinted in modified pdf format with kind permission of CRC Press. Standard personal use copyright restrictions apply.
Download PDF
(PDF, 29 pp, 277 KB)

CODDD Invited Review Publication - 2002
Richard AM, Williams CR, and Cariello NF (2002) Improving structure-linked access to publicly available chemical toxicity information, Current Opinion in Drug Discovery & Development (CODDD), 5(1):136-143.
Reprinted in modified pdf format with kind permission of Current Drugs, Lmt. Standard personal use copyright restrictions apply.
Download PDF
(PDF, 8 pp, 70 KB)

Original DSSTox Publication in Mutation Research - 2002
Richard AM and Williams CR (2002) Distributed Structure-Searchable Toxicity (DSSTox) Public Database Network: A Proposal, Mutation Research: New Frontiers, 499:27-52.
Reprinted in modified pdf format with kind permission of Elsevier Science. Standard personal use copyright restrictions apply.
Download PDF (PDF, 28 pp, 390 KB)


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