Premenopausal, ER-positive or PR-positive |
Chemotherapy plus tamoxifen, chemotherapy plus ovarian ablation/GnRH analog, chemotherapy plus tamoxifen plus ovarian ablation/GnRH analog*, ovarian ablation alone or with tamoxifen or GnRH alone or with tamoxifen |
Premenopausal, ER-negative or PR-negative |
Chemotherapy |
Postmenopausal, ER-positive or PR-positive |
Tamoxifen plus chemotherapy, tamoxifen alone |
Postmenopausal, ER-negative or PR-negative |
Chemotherapy |
Older than 70 years |
Tamoxifen alone; consider chemotherapy if receptor-negative |