Centers for Disease Control and Prevention Centers for Disease Control and Prevention CDC Home Search CDC CDC Health Topics A-Z site search
National Office of Public Health Genomics
Centers for Disease Control and Prevention
Office of Genomics and Disease Prevention
Site Search
 

HugeNet™

Genomics and Health Weekly Update

Human Genome Epidemiology (HuGE) Articles
October 5, 2006
Volume 17, No. 14

Return to Weekly Update

Many of the news links published in our Weekly Update are temporary, and we cannot guarantee access to stories longer than one or two weeks after the Update is published. We suggest you contact the news source directly for reprints.

These articles report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests.



Gene Variant Frequency

Prevalence of factor V R2 (H1299R) polymorphism in the Lebanese population
Zaatari GS, et al.
Pathology 2006 Oct;38(5):442-4

Frequency of the hemochromatosis gene (HFE) 282C-->Y, 63H-->D, and 65S-->C mutations in a general Mediterranean population from Tarragona, Spain
Aranda N, et al.
Ann Hematol 2006 Sep

 

Infectious and Parasitic Diseases

Interleukin-1 gene cluster polymorphism in chagas disease in a colombian case-control study
Florez O, et al.
Hum Immunol 2006 Sep;67(9):741-8

Association of promoter polymorphism of the CD14 C (-159) T endotoxin receptor gene with chronic hepatitis B
Mohammad Alizadeh AH, et al.
World J Gastroenterol 2006 Sep;12(35):5717-20

Eradication rate of Helicobacter pylori according to genotypes of CYP2C19, IL-1B, and TNF-A
Ishida Y, et al.
Int J Med Sci 2006;3(4):135-40

Short mucin 6 alleles are associated with H pylori infection
Nguyen TV, et al.
World J Gastroenterol 2006 Oct;12(37):6021-5

Sarcoidosis and a MIF gene polymorphism: a case-control study in an Irish Population
Plant BJ, et al.
Eur Respir J 2006 Sep

           

 

Neoplasms

Case-control, kin-cohort and meta-analyses provide no support for STK15 F31I as a low penetrance colorectal cancer allele
Webb EL, et al.
Br J Cancer 2006 Sep

Androgen receptor and vitamin D receptor gene polymorphisms and prostate cancer risk
Andersson P, et al.
Eur J Cancer 2006 Sep

The 3' untranslated region C > T polymorphism of prohibitin is a breast cancer risk modifier in Polish women carrying a BRCA1 mutation
Jakubowska A, et al.
Breast Cancer Res Treat 2006 Sep

A comprehensive examination of CYP19 variation and risk of breast cancer using two haplotype-tagging approaches
Olson JE, et al.
Breast Cancer Res Treat 2006 Sep

SULT1A1 genotype and susceptibility to colorectal cancer
Lilla C, et al.
Int J Cancer 2006 Sep

Combined effects of p73 and MDM2 polymorphisms on the risk of lung cancer
Jun HJ, et al.
Mol Carcinog 2006 Sep

Effects of cyclin D1 (CCND1) polymorphism on susceptibility to lung cancer in a North Indian population
Sobti RC, et al.
Cancer Genet Cytogenet 2006 Oct;170(2):108-14

HLA-class II haplotype associations with ovarian cancer
Kubler K, et al.
Int J Cancer 2006 Oct

Variations in exon 7 of the MSH2 gene and susceptibility to gastrointestinal cancer in a Chinese population
Fan Y, et al.
Cancer Genet Cytogenet 2006 Oct;170(2):121-8

Which Gene is a Dominant Predictor of Response During FOLFOX Chemotherapy for the Treatment of Metastatic Colorectal Cancer, the MTHFR or XRCC1 Gene?
Suh KW, et al.
Ann Surg Oncol 2006 Sep

Interactive effect of genetic polymorphism of glutathione S-transferase M1 and smoking on squamous cell lung cancer risk in Korea
Lee KM, et al.
Oncol Rep 2006 Nov;16(5):1035-9

A polymorphism of C-to-T substitution at -31 IL1B is associated with the risk of advanced gastric adenocarcinoma in a Japanese population
Ikehara SK, et al.
J Hum Genet 2006 Sep

Genetic polymorphisms in anti-inflammatory cytokine signaling and the prevalence of gastric precancerous lesions in Venezuela
Kato I, et al.
Cancer Causes Control 2006 Nov;17(9):1183-91

-765G > C COX-2 polymorphism may be a susceptibility marker for gastric adenocarcinoma in patients with atrophy or intestinal metaplasia
Pereira C, et al.
World J Gastroenterol 2006 Sep;12(34):5473-8

Polymorphisms in the FAS and FASL genes and risk of lung cancer in a Korean population
Park SH, et al.
Lung Cancer 2006 Sep

Promoter SNPs in G1/S checkpoint regulators and their impact on the susceptibility to childhood leukemia
Healy J, et al.
Blood 2006 Sep

Xeroderma pigmentosum group D 751 polymorphism as a predictive factor in resected gastric cancer treated with chemo-radiotherapy
Zarate R RN, et al.
World J Gastroenterol 2006 Oct;12(37):6032-6

 

Endocrine, Nutritional and Metabolic Diseases

Transcription Factor TCF7L2 Genetic Study in the French Population: Expression in Human {beta}-Cells and Adipose Tissue and Strong Association With Type 2 Diabetes
Cauchi S, et al.
Diabetes 2006 Oct;55(10):2903-8

Association between cord blood IgE and genetic polymorphisms of interleukin-4, the beta-subunit of the high-affinity receptor for IgE, lymphotoxin-alpha, and tumor Necrosis factor-alpha
Wen HJ, et al.
Pediatr Allergy Immunol 2006 Nov;17(7):489-94

Polymorphisms of the CD14 gene and atopic phenotypes in Czech patients with IgE-mediated allergy
Buckova D, et al.
J Hum Genet 2006 Sep

The {alpha}-Adducin Gene Is Associated With Macrovascular Complications and Mortality in Patients With Type 2 Diabetes
Yazdanpanah M, et al.
Diabetes 2006 Oct;55(10):2922-7

Exon 3-deleted/full-length growth hormone receptor polymorphism (d3/fl-GHR) genotype frequencies in Spanish short small-for-gestational-age (SGA) children and adolescents (n = 247) and in an adult control population (n = 289) show increased fl/fl in short SGA
Audi L, et al.
J Clin Endocrinol Metab 2006 Sep

Common Single Nucleotide Polymorphisms in TCF7L2 Are Reproducibly Associated With Type 2 Diabetes and Reduce the Insulin Response to Glucose in Nondiabetic Individuals
Saxena R, et al.
Diabetes 2006 Oct;55(10):2890-5

A Haplotype-Based Analysis of the PTPN22 Locus in Type 1 Diabetes
Onengut-Gumuscu S, et al.
Diabetes 2006 Oct;55(10):2883-9

Common Haplotypes at the Adiponectin Receptor 1 (ADIPOR1) Locus Are Associated With Increased Risk of Coronary Artery Disease in Type 2 Diabetes
Soccio T, et al.
Diabetes 2006 Oct;55(10):2763-70

Genetic factors for obesity
Yamada Y, et al.
Int J Mol Med 2006 Nov;18(5):843-51

Increased prevalence of VNTR III of the insulin gene in women with gestational diabetes mellitus (GDM)
Litou H, et al.
Diabetes Res Clin Pract 2006 Sep

Human Leukocyte Antigen Non-Class II Determinants for Type 1 Diabetes in the Finnish Population
Gombos Z, et al.
Hum Immunol 2006 Sep;67(9):714-21

IL6 Gene Promoter Polymorphisms and Type 2 Diabetes: Joint Analysis of Individual Participants' Data From 21 Studies
Huth C, et al.
Diabetes 2006 Oct;55(10):2915-21

The association between HTR2C polymorphisms and obesity in psychiatric patients using antipsychotics: a cross-sectional study
Mulder H, et al.
Pharmacogenomics J 2006 Oct

Arg753Gln TLR-2 Polymorphism in Familial Mediterranean Fever: Linking the Environment to the Phenotype in a Monogenic Inflammatory Disease
Ozen S, et al.
J Rheumatol 2006 Oct

The mtDNA 15497 G/A polymorphism in cytochrome b in severe obese subjects from Southern Italy
Liguori R, et al.
Nutr Metab Cardiovasc Dis 2006 Oct;16(7):466-70

Role of a Proline Insertion in the Insulin Promoter Factor 1 (IPF1) Gene in African Americans With Type 2 Diabetes
Elbein SC, et al.
Diabetes 2006 Oct;55(10):2909-14

 

Diseases of the Blood & Blood-Forming Organ Disorders

Screening for inherited thrombophilia might be warranted among Eastern Mediterranean sickle-sseta-0 thalassemia patients
Isma'eel H, et al.
J Thromb Thrombolysis 2006 Oct;22(2):121-3

Red blood cell disorders in Rwandese neonates: screening for sickle cell disease and glucose-6-phosphate dehydrogenase deficiency
Munyanganizi R, et al.
J Med Screen 2006;13(3):129-31

 

Mental Disorders

Determinants of the rate of nicotine metabolism and effects on smoking behavior
Johnstone E, et al.
Clin Pharmacol Ther 2006 Oct;80(4):319-30

Effect of 5-HT1A Receptor Gene Polymorphism on Negative and Depressive Symptom Response to Antipsychotic Treatment of Drug-Naive Psychotic Patients
Reynolds GP, et al.
Am J Psychiatry 2006 Oct;163(10):1826-9

Phosphodiesterase genes are associated with susceptibility to major depression and antidepressant treatment response
Wong ML, et al.
Proc Natl Acad Sci U S A 2006 Sep

Childhood maltreatment, subsequent antisocial behavior, and the role of monoamine oxidase a genotype
Huizinga D, et al.
Biol Psychiatry 2006 Oct;60(7):677-83

Identification of the Slynar Gene (AY070435) and Related Brain Expressed Sequences as a Candidate Gene for Susceptibility to Affective Disorders Through Allelic and Haplotypic Association With Bipolar Disorder on Chromosome 12q24
Kalsi G, et al.
Am J Psychiatry 2006 Oct;163(10):1767-76

Evidence for statistical epistasis between catechol-O-methyltransferase (COMT) and polymorphisms in RGS4, G72 (DAOA), GRM3, and DISC1: influence on risk of schizophrenia
Nicodemus KK, et al.
Hum Genet 2006 Sep

Brain-derived neurotrophic factor (BDNF) gene and rapid-cycling bipolar disorder: Family-based association study
Muller DJ, et al.
Br J Psychiatry 2006 Oct;189:317-23

Association Between Gene Polymorphisms of SLC22A3 and Methamphetamine Use Disorder
Aoyama N, et al.
Alcohol Clin Exp Res 2006 Oct;30(10):1644-9

           

 

Diseases of the Nervous System and Sense Organs

Association of HLA-DR and -DQ Genes with Narcolepsy in Koreans Comparison with Two Control Groups, Randomly Selected Subjects and DRB1*1501-DQB1*0602-Positive Subjects
Roh EY, et al.
Hum Immunol 2006 Sep;67(9):749-55

Genes related to iron metabolism and susceptibility to Alzheimer's disease in Basque population
Blazquez L, et al.
Neurobiol Aging 2006 Sep

Association of hsp70 polymorphisms with risk of noise-induced hearing loss in Chinese automobile workers
Yang M, et al.
Cell Stress Chaperones 2006 Autumn;11(3):233-9

KCNQ4: a gene for age-related hearing impairment?
Van Eyken E, et al.
Hum Mutat 2006 Oct;27(10):1007-16

 

Diseases of the Circulatory System

Candidate Gene Polymorphisms Do Not Differ Between Newborns With Stroke and Normal Controls
Miller SP, et al.
Stroke 2006 Sep

Does Pregnancy Increase Cardiac Risk for LQT1 Patients With the KCNQ1-A341V Mutation?
Heradien MJ, et al.
J Am Coll Cardiol 2006 Oct;48(7):1410-5

Hyperhomocysteinemia is a risk factor of recurrent coronary event in young patients irrespective to the MTHFR C677T polymorphism
Gonzalez-Porras JR, et al.
Thromb Res 2006 Sep

Genetic risk for atherothrombotic cerebral infarction in individuals stratified by sex or conventional risk factors for atherosclerosis
Yamaguchi S, et al.
Int J Mol Med 2006 Nov;18(5):871-83

Subsets of SNPs define rare genotype classes that predict ischemic heart disease
Frikke-Schmidt R, et al.
Hum Genet 2006 Sep

Gene polymorphisms implicated in influencing susceptibility to venous and arterial thromboembolism: Frequency distribution in a healthy German population
Hoppe B, et al.
Thromb Haemost 2006 Oct;96(4):465-70

Genetic variations of the endothelial nitric oxide synthase gene are related to increased levels of C-reactive protein and macrophage-colony stimulating-factor in patients with coronary artery disease
Lekakis JP, et al.
Thromb Haemost 2006 Oct;96(4):520-8

 

Diseases of the Respiratory System

Association of phosphodiesterase 4D gene polymorphisms with chronic obstructive pulmonary disease: Relationship to interleukin 13 gene polymorphism
Homma S, et al.
Int J Mol Med 2006 Nov;18(5):933-9

ACE gene polymorphism might disclose why some Taiwanese children with allergic rhinitis develop asthma symptoms but others do not
Lue KH, et al.
Pediatr Allergy Immunol 2006 Nov;17(7):508-13

Genetic association study between mbl2 and asthma phenotypes in Chinese children
Leung TF, et al.
Pediatr Allergy Immunol 2006 Nov;17(7):501-7

Surfactant protein C mutations in sporadic forms of idiopathic interstitial pneumonias
Markart P, et al.
Eur Respir J 2006 Sep

Estimation of the numbers and prevalences of the PI*S and PI*Z deficiency alleles of AAT Deficiency in Asia
de Serres FJ, et al.
Eur Respir J 2006 Sep

Gene-gene interaction between IL-13 and IL-13Ralpha1 is associated with total IgE in Korean children with atopic asthma
Kim HB, et al.
J Hum Genet 2006 Sep

Asp92Asn Polymorphism in the Myeloid IgA Fc Receptor Is Associated With Myocardial Infarction in Two Disparate Populations. CARE and WOSCOPS
Iakoubova OA, et al.
Arterioscler Thromb Vasc Biol 2006 Sep

Tissue Factor and Coagulation Factor VII Levels During Acute Myocardial Infarction. Association With Genotype and Adverse Events
Campo G, et al.
Arterioscler Thromb Vasc Biol 2006 Sep

 

Diseases of the Digestive System

New variations of the EDNRB gene and its association with sporadic Hirschsprung's disease in Korea
Kim JH, et al.
J Pediatr Surg 2006 Oct;41(10):1708-12

Prevalence of SLC22A4, SLC22A5 and CARD15 gene mutations in Hungarian pediatric patients with Crohn's disease
Bene J, et al.
World J Gastroenterol 2006 Sep;12(34):5550-3

Complex Insertion/Deletion Polymorphism in NOD1 (CARD4) is Not Associated with Inflammatory Bowel Disease Susceptibility in East Anglia Panel
Tremelling M, et al.
Inflamm Bowel Dis 2006 Oct;12(10):967-71

 

Diseases of the Genitourinary System

Effect of MTHFR C677T genotype on survival in type 2 diabetes patients with end-stage diabetic nephropathy
Boger CA, et al.
Nephrol Dial Transplant 2006 Sep

The Xylosyltransferase I Gene Polymorphism c.343G>T (p.A125S) Is a Risk Factor for Diabetic Nephropathy in Type 1 Diabetes
Schon S, et al.
Diabetes Care 2006 Oct;29(10):2295-9

 

Complications of Pregnancy, Childbirth, and the Puerperium

The CX3CL1-CX3CR1 system and psoriasis
Plant D, et al.
Exp Dermatol 2006 Nov;15(11):900-3

 

Complications of Pregnancy, Childbirth, and the Puerperium

p53 tumour suppressor gene polymorphism is associated with recurrent implantation failure
Kay C, et al.
Reprod Biomed Online 2006 Oct;13(4):492-6

 

Diseases of the Musculoskeletal System and Connective Tissue

Contribution of MHC class I region to genetic susceptibility for giant cell arteritis
Gonzalez-Gay MA, et al.
Rheumatology (Oxford) 2006 Sep

MHC class I chain-related gene B (MICB) is associated with rheumatoid arthritis susceptibility
Lopez-Arbesu R, et al.
Rheumatology (Oxford) 2006 Sep

Role of the MHC2TA gene in autoimmune diseases
Martinez A, et al.
Ann Rheum Dis 2006 Sep

Pharmacogenomic and metabolic biomarkers in the folate pathway and their association with methotrexate effects during dosage escalation in rheumatoid arthritis
Dervieux T, et al.
Arthritis Rheum 2006 Sep;54(10):3095-103

 

Congenital Anomalies

Mutation screening of BMP4, BMP7, HOXA4 and HOXB6 genes in Chinese patients with hypospadias
Chen T, et al.
Eur J Hum Genet 2006 Sep

 

 

For more information on HuGE, please visit the HuGENet™ home page

To receive notification of this update by e-mail, please send the following message:
To: listserv@listserv.cdc.gov
Subject: (leave blank)
Message: subscribe genetics

The CDC National Office of Public Health Genomics makes available the above information as a public service only.
Providing this information does not constitute endorsement by the CDC.  Note that some links may become invalid over time.

Page last reviewed: June 8, 2007 (archived document)
Page last updated: November 2, 2007
Content Source: National Office of Public Health Genomics